Comparison between Oncotype DX test and standard prognostic criteria in estrogen receptor positive early-stage breast cancer

Detalhes bibliográficos
Autor(a) principal: Freitas,Marcelo Roberto Pereira
Data de Publicação: 2011
Outros Autores: Simon,Sergio Daniel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Einstein (São Paulo)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082011000300354
Resumo: ABSTRACT Objective: To compare the prognosis estimated by standard prognostic criteria versus the prognosis estimated by the Oncotype DX. Methods: A retrospective study was performed on 22 patients with positive estrogen receptor, early-stage breast cancer who had an Oncotype DX recurrence score available. Results: Kappa value between Oncotype DX and standard prognostic criteria was: Adjuvant! (K = 0.091), Adjuvant! (Transbig) (K = 0.182) and National Comprehensive Cancer Network (K = 0.091). The Fisher's exact test did not show correlation between Oncotype and standard prognostic criteria. Conclusion: Standard prognostic criteria showed no correlation with Oncotype DX.
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spelling Comparison between Oncotype DX test and standard prognostic criteria in estrogen receptor positive early-stage breast cancerBreast neoplasms/diagnosisGene expression profilingABSTRACT Objective: To compare the prognosis estimated by standard prognostic criteria versus the prognosis estimated by the Oncotype DX. Methods: A retrospective study was performed on 22 patients with positive estrogen receptor, early-stage breast cancer who had an Oncotype DX recurrence score available. Results: Kappa value between Oncotype DX and standard prognostic criteria was: Adjuvant! (K = 0.091), Adjuvant! (Transbig) (K = 0.182) and National Comprehensive Cancer Network (K = 0.091). The Fisher's exact test did not show correlation between Oncotype and standard prognostic criteria. Conclusion: Standard prognostic criteria showed no correlation with Oncotype DX.Instituto Israelita de Ensino e Pesquisa Albert Einstein2011-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082011000300354einstein (São Paulo) v.9 n.3 2011reponame:Einstein (São Paulo)instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)instacron:IIEPAE10.1590/s1679-45082011ao2039info:eu-repo/semantics/openAccessFreitas,Marcelo Roberto PereiraSimon,Sergio Danieleng2017-03-10T00:00:00Zoai:scielo:S1679-45082011000300354Revistahttps://journal.einstein.br/pt-br/ONGhttps://old.scielo.br/oai/scielo-oai.php||revista@einstein.br2317-63851679-4508opendoar:2017-03-10T00:00Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)false
dc.title.none.fl_str_mv Comparison between Oncotype DX test and standard prognostic criteria in estrogen receptor positive early-stage breast cancer
title Comparison between Oncotype DX test and standard prognostic criteria in estrogen receptor positive early-stage breast cancer
spellingShingle Comparison between Oncotype DX test and standard prognostic criteria in estrogen receptor positive early-stage breast cancer
Freitas,Marcelo Roberto Pereira
Breast neoplasms/diagnosis
Gene expression profiling
title_short Comparison between Oncotype DX test and standard prognostic criteria in estrogen receptor positive early-stage breast cancer
title_full Comparison between Oncotype DX test and standard prognostic criteria in estrogen receptor positive early-stage breast cancer
title_fullStr Comparison between Oncotype DX test and standard prognostic criteria in estrogen receptor positive early-stage breast cancer
title_full_unstemmed Comparison between Oncotype DX test and standard prognostic criteria in estrogen receptor positive early-stage breast cancer
title_sort Comparison between Oncotype DX test and standard prognostic criteria in estrogen receptor positive early-stage breast cancer
author Freitas,Marcelo Roberto Pereira
author_facet Freitas,Marcelo Roberto Pereira
Simon,Sergio Daniel
author_role author
author2 Simon,Sergio Daniel
author2_role author
dc.contributor.author.fl_str_mv Freitas,Marcelo Roberto Pereira
Simon,Sergio Daniel
dc.subject.por.fl_str_mv Breast neoplasms/diagnosis
Gene expression profiling
topic Breast neoplasms/diagnosis
Gene expression profiling
description ABSTRACT Objective: To compare the prognosis estimated by standard prognostic criteria versus the prognosis estimated by the Oncotype DX. Methods: A retrospective study was performed on 22 patients with positive estrogen receptor, early-stage breast cancer who had an Oncotype DX recurrence score available. Results: Kappa value between Oncotype DX and standard prognostic criteria was: Adjuvant! (K = 0.091), Adjuvant! (Transbig) (K = 0.182) and National Comprehensive Cancer Network (K = 0.091). The Fisher's exact test did not show correlation between Oncotype and standard prognostic criteria. Conclusion: Standard prognostic criteria showed no correlation with Oncotype DX.
publishDate 2011
dc.date.none.fl_str_mv 2011-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082011000300354
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082011000300354
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/s1679-45082011ao2039
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Israelita de Ensino e Pesquisa Albert Einstein
publisher.none.fl_str_mv Instituto Israelita de Ensino e Pesquisa Albert Einstein
dc.source.none.fl_str_mv einstein (São Paulo) v.9 n.3 2011
reponame:Einstein (São Paulo)
instname:Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
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instname_str Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
instacron_str IIEPAE
institution IIEPAE
reponame_str Einstein (São Paulo)
collection Einstein (São Paulo)
repository.name.fl_str_mv Einstein (São Paulo) - Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE)
repository.mail.fl_str_mv ||revista@einstein.br
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