New approach to curb the transmission of leprosy
Autor(a) principal: | |
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Data de Publicação: | 1989 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Hansenologia Internationalis (Online) |
Texto Completo: | https://periodicos.saude.sp.gov.br/hansenologia/article/view/35515 |
Resumo: | The effect of local treatment of nose of lepromatous type of patients with different formulations of rifampicin nasal rops/sprays was investigated in a large number of patients. The preparations were either sprayed or instilled into the nostrils after flushing the nostrils with normal saline at 370 C. It was observed that 10 mg/ml of rifampicin was effective in reducing the BI and MI to zero in nose in seven days in majority of the patients. No untoward effect was seen in any of the patients. It is suggested that nasal sprays/drops may be able to prevent the transmission of hanseniasis, as nose is recognised to be an important portal of exit of M. leprae. Further when rifampicin drops/sprays are used as soon as the diagnosis is made, the nasal deformity may be prevented. It is believed that local treatment along with systemic therapy would go a long way in controlling the transmission of hanseniasis. |
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New approach to curb the transmission of leprosyHanseníaseRifampicina em gotas eTratamento localHanseniasisRifampicin Nasal Drops and SpraysLocal TreatmentThe effect of local treatment of nose of lepromatous type of patients with different formulations of rifampicin nasal rops/sprays was investigated in a large number of patients. The preparations were either sprayed or instilled into the nostrils after flushing the nostrils with normal saline at 370 C. It was observed that 10 mg/ml of rifampicin was effective in reducing the BI and MI to zero in nose in seven days in majority of the patients. No untoward effect was seen in any of the patients. It is suggested that nasal sprays/drops may be able to prevent the transmission of hanseniasis, as nose is recognised to be an important portal of exit of M. leprae. Further when rifampicin drops/sprays are used as soon as the diagnosis is made, the nasal deformity may be prevented. It is believed that local treatment along with systemic therapy would go a long way in controlling the transmission of hanseniasis.O efeito do tratamento local do nariz de paciente do tipo lepromatoso com diferentes formulações de rifampicina em gotas ou "sprays" nasais, foi investigado em um grande número de pacientes. As preparações foram ou aspergidas ou instiladas dentro das narinas depois de sua limpeza por jato com solução salina normal a 37 0C. Observou-se que 10 mg/ml de rifampicina eram eficazes na redução do BI e do MI a zero no nariz em sete dias na maioria dos pacientes. Não foi visto efeito desagradável em qualquer dos pacientes. Sugere-se que "sprays"/gotas nasais possam prevenir a transmissão da hanseníase, uma vez que o nariz é reconhecido ser uma importante porta de salda de M. leprae. Além disso a deformidade nasal pode ser prevenida quando a rifampicina "sprays"/gotas é usada tão logo o diagnóstico é feito. Acredita-se que o tratamento local juntamente com a terapia sistémica contribuiriam muito no controle da transmissão da hanseníase.Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo1989-06-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado pelos paresapplication/pdfhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/3551510.47878/hi.1989.v14.35515Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 14 No. 1 (1989); 6-13Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 14 n. 1 (1989); 6-131982-5161reponame:Hansenologia Internationalis (Online)instname:Instituto Lauro de Souza Lima (ILSL)instacron:ILSLenghttps://periodicos.saude.sp.gov.br/hansenologia/article/view/35515/33930PRABHAKAR, M.C.RAO, A.V.N. APPAKRISHNA, D.R.RAMANAKAR, T.V.RAO, P.G.REDDY, K. NARSIMHAinfo:eu-repo/semantics/openAccess2021-06-03T00:28:02Zoai:ojs.periodicos.saude.sp.gov.br:article/35515Revistahttps://periodicos.saude.sp.gov.br/hansenologiaPRIhttps://periodicos.saude.sp.gov.br/hansenologia/oaihansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br1982-51610100-3283opendoar:2021-06-03T00:28:02Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)false |
dc.title.none.fl_str_mv |
New approach to curb the transmission of leprosy |
title |
New approach to curb the transmission of leprosy |
spellingShingle |
New approach to curb the transmission of leprosy PRABHAKAR, M.C. Hanseníase Rifampicina em gotas e Tratamento local Hanseniasis Rifampicin Nasal Drops and Sprays Local Treatment |
title_short |
New approach to curb the transmission of leprosy |
title_full |
New approach to curb the transmission of leprosy |
title_fullStr |
New approach to curb the transmission of leprosy |
title_full_unstemmed |
New approach to curb the transmission of leprosy |
title_sort |
New approach to curb the transmission of leprosy |
author |
PRABHAKAR, M.C. |
author_facet |
PRABHAKAR, M.C. RAO, A.V.N. APPA KRISHNA, D.R. RAMANAKAR, T.V. RAO, P.G. REDDY, K. NARSIMHA |
author_role |
author |
author2 |
RAO, A.V.N. APPA KRISHNA, D.R. RAMANAKAR, T.V. RAO, P.G. REDDY, K. NARSIMHA |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
PRABHAKAR, M.C. RAO, A.V.N. APPA KRISHNA, D.R. RAMANAKAR, T.V. RAO, P.G. REDDY, K. NARSIMHA |
dc.subject.por.fl_str_mv |
Hanseníase Rifampicina em gotas e Tratamento local Hanseniasis Rifampicin Nasal Drops and Sprays Local Treatment |
topic |
Hanseníase Rifampicina em gotas e Tratamento local Hanseniasis Rifampicin Nasal Drops and Sprays Local Treatment |
description |
The effect of local treatment of nose of lepromatous type of patients with different formulations of rifampicin nasal rops/sprays was investigated in a large number of patients. The preparations were either sprayed or instilled into the nostrils after flushing the nostrils with normal saline at 370 C. It was observed that 10 mg/ml of rifampicin was effective in reducing the BI and MI to zero in nose in seven days in majority of the patients. No untoward effect was seen in any of the patients. It is suggested that nasal sprays/drops may be able to prevent the transmission of hanseniasis, as nose is recognised to be an important portal of exit of M. leprae. Further when rifampicin drops/sprays are used as soon as the diagnosis is made, the nasal deformity may be prevented. It is believed that local treatment along with systemic therapy would go a long way in controlling the transmission of hanseniasis. |
publishDate |
1989 |
dc.date.none.fl_str_mv |
1989-06-30 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Avaliado pelos pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.saude.sp.gov.br/hansenologia/article/view/35515 10.47878/hi.1989.v14.35515 |
url |
https://periodicos.saude.sp.gov.br/hansenologia/article/view/35515 |
identifier_str_mv |
10.47878/hi.1989.v14.35515 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://periodicos.saude.sp.gov.br/hansenologia/article/view/35515/33930 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo |
publisher.none.fl_str_mv |
Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo |
dc.source.none.fl_str_mv |
Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 14 No. 1 (1989); 6-13 Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 14 n. 1 (1989); 6-13 1982-5161 reponame:Hansenologia Internationalis (Online) instname:Instituto Lauro de Souza Lima (ILSL) instacron:ILSL |
instname_str |
Instituto Lauro de Souza Lima (ILSL) |
instacron_str |
ILSL |
institution |
ILSL |
reponame_str |
Hansenologia Internationalis (Online) |
collection |
Hansenologia Internationalis (Online) |
repository.name.fl_str_mv |
Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL) |
repository.mail.fl_str_mv |
hansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br |
_version_ |
1796797579723276288 |