Immunoglobulin deposits in Erythema Nodosum Leprosum (ENL) JOSEPHINE ANTHON

Detalhes bibliográficos
Autor(a) principal: ANTHONY, JOSEPHINE
Data de Publicação: 1978
Outros Autores: VAIDYA, M. C., DASGUPTA, A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Hansenologia Internationalis (Online)
DOI: 10.47878/hi.1978.v3.35637
Texto Completo: https://periodicos.saude.sp.gov.br/hansenologia/article/view/35637
Resumo: Erythema Nodosum Leprosum (ENL) skin lesions observed by fluorescence microscopy were found to contain immune complexes. While biopsies taken from at least seven ENL lesions contained deposits of immunoglobulin in their vessel walls, twelve of the lesions contained such deposits in the perivascular cell infiltrate. However, immunoglobulin deposits were observed in the dermis of all 25 ENL lesions studied. On the basis of localization of these fluorescent deposits the 25 skin lesions were classified under groups I to III and were correlated with the onset of the reaction. Control biopsies taken from the lepromatous leprosy patients without ENL were uniformly negative for immunoglobulin deposits.
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spelling Immunoglobulin deposits in Erythema Nodosum Leprosum (ENL) JOSEPHINE ANTHONHanseniasisENL reactionImmunologyImmunofluorescenceErythema Nodosum Leprosum (ENL) skin lesions observed by fluorescence microscopy were found to contain immune complexes. While biopsies taken from at least seven ENL lesions contained deposits of immunoglobulin in their vessel walls, twelve of the lesions contained such deposits in the perivascular cell infiltrate. However, immunoglobulin deposits were observed in the dermis of all 25 ENL lesions studied. On the basis of localization of these fluorescent deposits the 25 skin lesions were classified under groups I to III and were correlated with the onset of the reaction. Control biopsies taken from the lepromatous leprosy patients without ENL were uniformly negative for immunoglobulin deposits.Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo1978-06-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado pelos paresapplication/pdfhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/3563710.47878/hi.1978.v3.35637Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 3 No. 1 (1978); 12-17Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 3 n. 1 (1978); 12-171982-5161reponame:Hansenologia Internationalis (Online)instname:Instituto Lauro de Souza Lima (ILSL)instacron:ILSLenghttps://periodicos.saude.sp.gov.br/hansenologia/article/view/35637/34043ANTHONY, JOSEPHINEVAIDYA, M. C.DASGUPTA, A.info:eu-repo/semantics/openAccess2021-05-20T21:13:22Zoai:ojs.periodicos.saude.sp.gov.br:article/35637Revistahttps://periodicos.saude.sp.gov.br/hansenologiaPRIhttps://periodicos.saude.sp.gov.br/hansenologia/oaihansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br1982-51610100-3283opendoar:2021-05-20T21:13:22Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)false
dc.title.none.fl_str_mv Immunoglobulin deposits in Erythema Nodosum Leprosum (ENL) JOSEPHINE ANTHON
title Immunoglobulin deposits in Erythema Nodosum Leprosum (ENL) JOSEPHINE ANTHON
spellingShingle Immunoglobulin deposits in Erythema Nodosum Leprosum (ENL) JOSEPHINE ANTHON
Immunoglobulin deposits in Erythema Nodosum Leprosum (ENL) JOSEPHINE ANTHON
ANTHONY, JOSEPHINE
Hanseniasis
ENL reaction
Immunology
Immunofluorescence
ANTHONY, JOSEPHINE
Hanseniasis
ENL reaction
Immunology
Immunofluorescence
title_short Immunoglobulin deposits in Erythema Nodosum Leprosum (ENL) JOSEPHINE ANTHON
title_full Immunoglobulin deposits in Erythema Nodosum Leprosum (ENL) JOSEPHINE ANTHON
title_fullStr Immunoglobulin deposits in Erythema Nodosum Leprosum (ENL) JOSEPHINE ANTHON
Immunoglobulin deposits in Erythema Nodosum Leprosum (ENL) JOSEPHINE ANTHON
title_full_unstemmed Immunoglobulin deposits in Erythema Nodosum Leprosum (ENL) JOSEPHINE ANTHON
Immunoglobulin deposits in Erythema Nodosum Leprosum (ENL) JOSEPHINE ANTHON
title_sort Immunoglobulin deposits in Erythema Nodosum Leprosum (ENL) JOSEPHINE ANTHON
author ANTHONY, JOSEPHINE
author_facet ANTHONY, JOSEPHINE
ANTHONY, JOSEPHINE
VAIDYA, M. C.
DASGUPTA, A.
VAIDYA, M. C.
DASGUPTA, A.
author_role author
author2 VAIDYA, M. C.
DASGUPTA, A.
author2_role author
author
dc.contributor.author.fl_str_mv ANTHONY, JOSEPHINE
VAIDYA, M. C.
DASGUPTA, A.
dc.subject.por.fl_str_mv Hanseniasis
ENL reaction
Immunology
Immunofluorescence
topic Hanseniasis
ENL reaction
Immunology
Immunofluorescence
description Erythema Nodosum Leprosum (ENL) skin lesions observed by fluorescence microscopy were found to contain immune complexes. While biopsies taken from at least seven ENL lesions contained deposits of immunoglobulin in their vessel walls, twelve of the lesions contained such deposits in the perivascular cell infiltrate. However, immunoglobulin deposits were observed in the dermis of all 25 ENL lesions studied. On the basis of localization of these fluorescent deposits the 25 skin lesions were classified under groups I to III and were correlated with the onset of the reaction. Control biopsies taken from the lepromatous leprosy patients without ENL were uniformly negative for immunoglobulin deposits.
publishDate 1978
dc.date.none.fl_str_mv 1978-06-30
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.saude.sp.gov.br/hansenologia/article/view/35637
10.47878/hi.1978.v3.35637
url https://periodicos.saude.sp.gov.br/hansenologia/article/view/35637
identifier_str_mv 10.47878/hi.1978.v3.35637
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://periodicos.saude.sp.gov.br/hansenologia/article/view/35637/34043
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo
publisher.none.fl_str_mv Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo
dc.source.none.fl_str_mv Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 3 No. 1 (1978); 12-17
Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 3 n. 1 (1978); 12-17
1982-5161
reponame:Hansenologia Internationalis (Online)
instname:Instituto Lauro de Souza Lima (ILSL)
instacron:ILSL
instname_str Instituto Lauro de Souza Lima (ILSL)
instacron_str ILSL
institution ILSL
reponame_str Hansenologia Internationalis (Online)
collection Hansenologia Internationalis (Online)
repository.name.fl_str_mv Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)
repository.mail.fl_str_mv hansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br
_version_ 1822182094319648768
dc.identifier.doi.none.fl_str_mv 10.47878/hi.1978.v3.35637

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