Alteración de la inminidad mediada por células frente a Mycobacterium leprae y mycobacterium marinum en pacientes hansenianos

Detalhes bibliográficos
Autor(a) principal: FLIESS, Enrique L.
Data de Publicação: 1983
Outros Autores: ORTIZ, Maria C., CORN, Juan
Tipo de documento: Artigo
Idioma: spa
Título da fonte: Hansenologia Internationalis (Online)
Texto Completo: https://periodicos.saude.sp.gov.br/hansenologia/article/view/35579
Resumo: The cell mediated immunity (CMI) to protein purified derivates of Mycobacterium leprae, Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium marinum was studied. Leukocyte Migration Inhibition (LMI) and Delayed Hypersensitivy skin reactions to these antigens were examined in 44 hanseniasis patients (20 quiescent Virchowians, 13 reactional Virchowians and 11 tuberculoid patients) and 15 healthy subjects. An impairment in LMI and Delayed Hypersensitivity tests to M. leprae and M. maximum was observed in Virchowians patients both quiescent and reactional. The CMI response to all mycobacterial antigens was increased in tuberculoid patients and was observed a poor response to M. leprae and M. marinum in healthy controls. Our results show a high correlation between the CMI response to M. leprae and to M. marinum (r = + 0,8). This close relationship between both antigens may express.cross-reactivity.
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spelling Alteración de la inminidad mediada por células frente a Mycobacterium leprae y mycobacterium marinum en pacientes hansenianosCell mediated immunityMycobacterium lepraeMycobacterium marinumInmunidad mediada por célulasMycobacterium lepraeMycobacterium marinumThe cell mediated immunity (CMI) to protein purified derivates of Mycobacterium leprae, Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium marinum was studied. Leukocyte Migration Inhibition (LMI) and Delayed Hypersensitivy skin reactions to these antigens were examined in 44 hanseniasis patients (20 quiescent Virchowians, 13 reactional Virchowians and 11 tuberculoid patients) and 15 healthy subjects. An impairment in LMI and Delayed Hypersensitivity tests to M. leprae and M. maximum was observed in Virchowians patients both quiescent and reactional. The CMI response to all mycobacterial antigens was increased in tuberculoid patients and was observed a poor response to M. leprae and M. marinum in healthy controls. Our results show a high correlation between the CMI response to M. leprae and to M. marinum (r = + 0,8). This close relationship between both antigens may express.cross-reactivity.Se estudió la inmunidad mediada por células (IMC) frente a derivados proteicos purificados de Mycobacterium leprae, Mycobacterium tuberculosis, Myco- bacterium avium y Mycobacterium marinum. Se efectuaron tests cutineos de  hipersensibilidad retardada einhibicién de la migración de leucocitos in vitro en 44 pacientes hansenianos (20 virchowianos quiescentes, 13 virchowianos reaccionales y 11 tuberculoides) y en 15 testigos sanos. Se observóuna alteración de la inhibicifin de la migración de leucocitos y de la hipersensibilidad cutinea frente a M. leprae y M. marinum en los pacientes vircho- wianos, quiescentes y reaccionales. La respuesta de la IMC frente a todos los antigenos micobacterianos se encontró aumentada en los pacientes tuberculoides, y se observó una respuesta débil frente a M. leprae y M. marinum en los controles sanos. Los  resultados obtenidos muestran una estrecha correlación entre la IMC frente a M. leprae y M. marinum en todos los casos, la cual podria expresar reactividad cruzada entre ambos antígenos.Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo1983-06-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado pelos paresapplication/pdfhttps://periodicos.saude.sp.gov.br/hansenologia/article/view/3557910.47878/hi.1983.v8.35579Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 8 No. 1 (1983); 9-17Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 8 n. 1 (1983); 9-171982-5161reponame:Hansenologia Internationalis (Online)instname:Instituto Lauro de Souza Lima (ILSL)instacron:ILSLspahttps://periodicos.saude.sp.gov.br/hansenologia/article/view/35579/33985FLIESS, Enrique L.ORTIZ, Maria C.CORN, Juaninfo:eu-repo/semantics/openAccess2021-06-06T03:56:37Zoai:ojs.periodicos.saude.sp.gov.br:article/35579Revistahttps://periodicos.saude.sp.gov.br/hansenologiaPRIhttps://periodicos.saude.sp.gov.br/hansenologia/oaihansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br1982-51610100-3283opendoar:2021-06-06T03:56:37Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)false
dc.title.none.fl_str_mv Alteración de la inminidad mediada por células frente a Mycobacterium leprae y mycobacterium marinum en pacientes hansenianos
title Alteración de la inminidad mediada por células frente a Mycobacterium leprae y mycobacterium marinum en pacientes hansenianos
spellingShingle Alteración de la inminidad mediada por células frente a Mycobacterium leprae y mycobacterium marinum en pacientes hansenianos
FLIESS, Enrique L.
Cell mediated immunity
Mycobacterium leprae
Mycobacterium marinum
Inmunidad mediada por células
Mycobacterium leprae
Mycobacterium marinum
title_short Alteración de la inminidad mediada por células frente a Mycobacterium leprae y mycobacterium marinum en pacientes hansenianos
title_full Alteración de la inminidad mediada por células frente a Mycobacterium leprae y mycobacterium marinum en pacientes hansenianos
title_fullStr Alteración de la inminidad mediada por células frente a Mycobacterium leprae y mycobacterium marinum en pacientes hansenianos
title_full_unstemmed Alteración de la inminidad mediada por células frente a Mycobacterium leprae y mycobacterium marinum en pacientes hansenianos
title_sort Alteración de la inminidad mediada por células frente a Mycobacterium leprae y mycobacterium marinum en pacientes hansenianos
author FLIESS, Enrique L.
author_facet FLIESS, Enrique L.
ORTIZ, Maria C.
CORN, Juan
author_role author
author2 ORTIZ, Maria C.
CORN, Juan
author2_role author
author
dc.contributor.author.fl_str_mv FLIESS, Enrique L.
ORTIZ, Maria C.
CORN, Juan
dc.subject.por.fl_str_mv Cell mediated immunity
Mycobacterium leprae
Mycobacterium marinum
Inmunidad mediada por células
Mycobacterium leprae
Mycobacterium marinum
topic Cell mediated immunity
Mycobacterium leprae
Mycobacterium marinum
Inmunidad mediada por células
Mycobacterium leprae
Mycobacterium marinum
description The cell mediated immunity (CMI) to protein purified derivates of Mycobacterium leprae, Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium marinum was studied. Leukocyte Migration Inhibition (LMI) and Delayed Hypersensitivy skin reactions to these antigens were examined in 44 hanseniasis patients (20 quiescent Virchowians, 13 reactional Virchowians and 11 tuberculoid patients) and 15 healthy subjects. An impairment in LMI and Delayed Hypersensitivity tests to M. leprae and M. maximum was observed in Virchowians patients both quiescent and reactional. The CMI response to all mycobacterial antigens was increased in tuberculoid patients and was observed a poor response to M. leprae and M. marinum in healthy controls. Our results show a high correlation between the CMI response to M. leprae and to M. marinum (r = + 0,8). This close relationship between both antigens may express.cross-reactivity.
publishDate 1983
dc.date.none.fl_str_mv 1983-06-30
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.saude.sp.gov.br/hansenologia/article/view/35579
10.47878/hi.1983.v8.35579
url https://periodicos.saude.sp.gov.br/hansenologia/article/view/35579
identifier_str_mv 10.47878/hi.1983.v8.35579
dc.language.iso.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv https://periodicos.saude.sp.gov.br/hansenologia/article/view/35579/33985
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo
publisher.none.fl_str_mv Instituto Lauro de Souza Lima da Secretaria de Estado da Saúde de São Paulo
dc.source.none.fl_str_mv Hansenologia Internationalis: leprosy and other infectious diseases; Vol. 8 No. 1 (1983); 9-17
Hansenologia Internationalis: hanseníase e outras doenças infecciosas; v. 8 n. 1 (1983); 9-17
1982-5161
reponame:Hansenologia Internationalis (Online)
instname:Instituto Lauro de Souza Lima (ILSL)
instacron:ILSL
instname_str Instituto Lauro de Souza Lima (ILSL)
instacron_str ILSL
institution ILSL
reponame_str Hansenologia Internationalis (Online)
collection Hansenologia Internationalis (Online)
repository.name.fl_str_mv Hansenologia Internationalis (Online) - Instituto Lauro de Souza Lima (ILSL)
repository.mail.fl_str_mv hansen_int@ilsl.br || hansenologia.internationalis@gmail.com || periodicossp@saude.sp.gov.br
_version_ 1796797579775705088

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