Serotype, mating type and ploidy of Cryptococcus neoformans strains isolated from patients in Brazil

Detalhes bibliográficos
Autor(a) principal: OHKUSU, Misako
Data de Publicação: 2002
Outros Autores: TANGONAN, Naomi, TAKEO, Kanji, KISHIDA, Eriko, OHKUBO, Masami, AOKI, Shigeji, NAKAMURA, Kenjiro, FUJII, Takaaki, SIQUEIRA, Isadora C. de, MACIEL, Elves A.P., SAKABE, Sumire, ALMEIDA, Gisele M.D., HEINS-VACCARI, Elisabeth M., LACAZ, Carlos da S.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/30649
Resumo: Serotype, mating type and ploidy of 84 strains of Cryptococcus neoformans isolated from 61 AIDS and 23 non-AIDS patients admitted in a tertiary teaching hospital in São Paulo, Brazil were examined. Among 61 strains isolated from AIDS patients, 60 strains were var. grubii (serotype A). Only one strain was var. gattii (serotype B). No var. neoformans (serotype D) was found. Among 23 strains isolated from non-AIDS patients, 15 were var. grubii (serotype A) and the remaining 8 were var. gattii, all of which were serotype B. Seventy-three of the 75 serotype A strains were the heterothallic alpha type (MATalpha) and the remaining 2 were untypable (asexual). Most of the MATalpha strains (69/73) were haploid and the remaining 4 strains were diploid. Similarly, both of the 2 asexual strains among the 75 serotype A strains were haploid. There were no alpha-mating type (MATalpha) strains among the 84 isolates. All of the 8 var. gattii strains were serotype B and haploid. Among a total of 84 strains tested, neither serotype AD nor serotype D were found. Neither triploid nor tetraploid were found. These results suggest that the serological, sexual and ploidy characteristics in C. neoformans strains isolated from AIDS patients in São Paulo were rather simple, whereas strains isolated from non-AIDS patients presented serotype A and B with predominance of serotype A.
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spelling Serotype, mating type and ploidy of Cryptococcus neoformans strains isolated from patients in Brazil Sorotipos, "mating type" e ploidia de amostras de C. neoformans isoladas de pacientes no Brasil AIDSCryptococcus neoformansMating typePloidySerotype Serotype, mating type and ploidy of 84 strains of Cryptococcus neoformans isolated from 61 AIDS and 23 non-AIDS patients admitted in a tertiary teaching hospital in São Paulo, Brazil were examined. Among 61 strains isolated from AIDS patients, 60 strains were var. grubii (serotype A). Only one strain was var. gattii (serotype B). No var. neoformans (serotype D) was found. Among 23 strains isolated from non-AIDS patients, 15 were var. grubii (serotype A) and the remaining 8 were var. gattii, all of which were serotype B. Seventy-three of the 75 serotype A strains were the heterothallic alpha type (MATalpha) and the remaining 2 were untypable (asexual). Most of the MATalpha strains (69/73) were haploid and the remaining 4 strains were diploid. Similarly, both of the 2 asexual strains among the 75 serotype A strains were haploid. There were no alpha-mating type (MATalpha) strains among the 84 isolates. All of the 8 var. gattii strains were serotype B and haploid. Among a total of 84 strains tested, neither serotype AD nor serotype D were found. Neither triploid nor tetraploid were found. These results suggest that the serological, sexual and ploidy characteristics in C. neoformans strains isolated from AIDS patients in São Paulo were rather simple, whereas strains isolated from non-AIDS patients presented serotype A and B with predominance of serotype A. Foram estudados os sorotipos, "mating type" e ploidia de 84 amostras de C. neoformans isoladas de 61 pacientes com AIDS e 23 não-AIDS em São Paulo. Das amostras isoladas de pacientes com AIDS, 60 foram identificadas como var. grubii (sorotipo A) e 1 como var. gattii (sorotipo B). Não houve isolamento do sorotipo D. Entre as amostras isoladas, de pacientes não-AIDS, 15 foram de var. grubii (sorotipo A) e as 8 restantes de var. gattii, todos do sorotipo B. Setenta e três dos 75 sorotipos A foram identificadas como cepas heterotálicas do fenótipo alfa (MATalfa) e as 2 remanescentes não-tipáveis (assexuada), eram haplóides. A maioria das cepas MATalfa (69/73) era haplóide sendo 4 diplóide. Não houve o isolamento de fenótipo a (MATa) entre as 84 cepas analisadas. Todas as 11 amostras de var. gattii eram do sorotipo B e haplóides. Não foram observados os sorotipos AD e C, nem células triplóides ou tetraplóides entre as 84 amostras estudadas. Os resultados sugerem, que as características sorológicas, sexuais e de ploidia de C. neoformans, isoladas de pacientes com AIDS em São Paulo, são particularmente simples, a maioria do sorotipo A, enquanto que nos pacientes não-AIDS foram observados tanto os sorotipos A quanto o B. Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo2002-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/30649Revista do Instituto de Medicina Tropical de São Paulo; Vol. 44 No. 6 (2002); 299-302 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 44 Núm. 6 (2002); 299-302 Revista do Instituto de Medicina Tropical de São Paulo; v. 44 n. 6 (2002); 299-302 1678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/30649/32533Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessOHKUSU, MisakoTANGONAN, NaomiTAKEO, KanjiKISHIDA, ErikoOHKUBO, MasamiAOKI, ShigejiNAKAMURA, KenjiroFUJII, TakaakiSIQUEIRA, Isadora C. deMACIEL, Elves A.P.SAKABE, SumireALMEIDA, Gisele M.D.HEINS-VACCARI, Elisabeth M.LACAZ, Carlos da S.2012-07-07T17:53:25Zoai:revistas.usp.br:article/30649Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:51:25.353491Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true
dc.title.none.fl_str_mv Serotype, mating type and ploidy of Cryptococcus neoformans strains isolated from patients in Brazil
Sorotipos, "mating type" e ploidia de amostras de C. neoformans isoladas de pacientes no Brasil
title Serotype, mating type and ploidy of Cryptococcus neoformans strains isolated from patients in Brazil
spellingShingle Serotype, mating type and ploidy of Cryptococcus neoformans strains isolated from patients in Brazil
OHKUSU, Misako
AIDS
Cryptococcus neoformans
Mating type
Ploidy
Serotype
title_short Serotype, mating type and ploidy of Cryptococcus neoformans strains isolated from patients in Brazil
title_full Serotype, mating type and ploidy of Cryptococcus neoformans strains isolated from patients in Brazil
title_fullStr Serotype, mating type and ploidy of Cryptococcus neoformans strains isolated from patients in Brazil
title_full_unstemmed Serotype, mating type and ploidy of Cryptococcus neoformans strains isolated from patients in Brazil
title_sort Serotype, mating type and ploidy of Cryptococcus neoformans strains isolated from patients in Brazil
author OHKUSU, Misako
author_facet OHKUSU, Misako
TANGONAN, Naomi
TAKEO, Kanji
KISHIDA, Eriko
OHKUBO, Masami
AOKI, Shigeji
NAKAMURA, Kenjiro
FUJII, Takaaki
SIQUEIRA, Isadora C. de
MACIEL, Elves A.P.
SAKABE, Sumire
ALMEIDA, Gisele M.D.
HEINS-VACCARI, Elisabeth M.
LACAZ, Carlos da S.
author_role author
author2 TANGONAN, Naomi
TAKEO, Kanji
KISHIDA, Eriko
OHKUBO, Masami
AOKI, Shigeji
NAKAMURA, Kenjiro
FUJII, Takaaki
SIQUEIRA, Isadora C. de
MACIEL, Elves A.P.
SAKABE, Sumire
ALMEIDA, Gisele M.D.
HEINS-VACCARI, Elisabeth M.
LACAZ, Carlos da S.
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv OHKUSU, Misako
TANGONAN, Naomi
TAKEO, Kanji
KISHIDA, Eriko
OHKUBO, Masami
AOKI, Shigeji
NAKAMURA, Kenjiro
FUJII, Takaaki
SIQUEIRA, Isadora C. de
MACIEL, Elves A.P.
SAKABE, Sumire
ALMEIDA, Gisele M.D.
HEINS-VACCARI, Elisabeth M.
LACAZ, Carlos da S.
dc.subject.por.fl_str_mv AIDS
Cryptococcus neoformans
Mating type
Ploidy
Serotype
topic AIDS
Cryptococcus neoformans
Mating type
Ploidy
Serotype
description Serotype, mating type and ploidy of 84 strains of Cryptococcus neoformans isolated from 61 AIDS and 23 non-AIDS patients admitted in a tertiary teaching hospital in São Paulo, Brazil were examined. Among 61 strains isolated from AIDS patients, 60 strains were var. grubii (serotype A). Only one strain was var. gattii (serotype B). No var. neoformans (serotype D) was found. Among 23 strains isolated from non-AIDS patients, 15 were var. grubii (serotype A) and the remaining 8 were var. gattii, all of which were serotype B. Seventy-three of the 75 serotype A strains were the heterothallic alpha type (MATalpha) and the remaining 2 were untypable (asexual). Most of the MATalpha strains (69/73) were haploid and the remaining 4 strains were diploid. Similarly, both of the 2 asexual strains among the 75 serotype A strains were haploid. There were no alpha-mating type (MATalpha) strains among the 84 isolates. All of the 8 var. gattii strains were serotype B and haploid. Among a total of 84 strains tested, neither serotype AD nor serotype D were found. Neither triploid nor tetraploid were found. These results suggest that the serological, sexual and ploidy characteristics in C. neoformans strains isolated from AIDS patients in São Paulo were rather simple, whereas strains isolated from non-AIDS patients presented serotype A and B with predominance of serotype A.
publishDate 2002
dc.date.none.fl_str_mv 2002-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/30649
url https://www.revistas.usp.br/rimtsp/article/view/30649
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/30649/32533
dc.rights.driver.fl_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
dc.source.none.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo; Vol. 44 No. 6 (2002); 299-302
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 44 Núm. 6 (2002); 299-302
Revista do Instituto de Medicina Tropical de São Paulo; v. 44 n. 6 (2002); 299-302
1678-9946
0036-4665
reponame:Revista do Instituto de Medicina Tropical de São Paulo
instname:Instituto de Medicina Tropical (IMT)
instacron:IMT
instname_str Instituto de Medicina Tropical (IMT)
instacron_str IMT
institution IMT
reponame_str Revista do Instituto de Medicina Tropical de São Paulo
collection Revista do Instituto de Medicina Tropical de São Paulo
repository.name.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)
repository.mail.fl_str_mv ||revimtsp@usp.br
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