Response of human Plasmodium to antimalarial Drugs in S. Luis, Maranhão State, Brazil

Detalhes bibliográficos
Autor(a) principal: Silva, A. Rafael Da
Data de Publicação: 1984
Outros Autores: Carneiro, Ernane Wilson Bezerra, Santos, Henrique Jorge Dos
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/87273
Resumo: The Authors studied the response of human PLASMODIUM "in vivo" to antimalarial drugs in São Luís, Maranhão State, Brazil, during the years of 1981 and 1982. In the treatment of Plasmodium falciparum malaria was shown that 25.9% presented resistance to chloroquine and 16% to the association sulfonamide and pyrimethamine. With Plasmodium vivax it was found that effectiveness was 94.4% and 96% for both regimens of treatment. Finally the Authors suggest the use of the association chloroquine, primaquine and pyrimetamine in a three days scheme for better and low cost treatment. Also the associations sulfonamide, pyrimetamine and quinine as an alternative treatment for Plasmodium falciparum resistant to 4-amino-quinolines.
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spelling Response of human Plasmodium to antimalarial Drugs in S. Luis, Maranhão State, Brazil Resposta dos plasmódios humanos aos antimaláricos na ilha de São Luís, estado do Maranhão, Brasil The Authors studied the response of human PLASMODIUM "in vivo" to antimalarial drugs in São Luís, Maranhão State, Brazil, during the years of 1981 and 1982. In the treatment of Plasmodium falciparum malaria was shown that 25.9% presented resistance to chloroquine and 16% to the association sulfonamide and pyrimethamine. With Plasmodium vivax it was found that effectiveness was 94.4% and 96% for both regimens of treatment. Finally the Authors suggest the use of the association chloroquine, primaquine and pyrimetamine in a three days scheme for better and low cost treatment. Also the associations sulfonamide, pyrimetamine and quinine as an alternative treatment for Plasmodium falciparum resistant to 4-amino-quinolines. Os Autores estudaram a resposta dos plasmódios humanos "in vivo" aos antimaláricos na Ilha de São Luís, Estado do Maranhão, Brasil, durante os anos de 1981 e 1982. No tratamento de malária por P. falciparum definem o atual estado da resistência à cloroquina (25,9%) e a associação sulfamídicos e pirimetamina (16%). Quanto ao tratamento da malária por P. vivax, obtém índices de cura de 94,4% e 96% respectivamente, para dois esquemas testados. Finalmente, proclamam a utilização da associação cloroquina, primaquina e pirimetamina, em três dias, como o tratamento mais eficaz e de menor custo. Também a associação sulfamídicos e pirimetamina e a quinina ainda como drogas alternativas para tratamento do P. falciparum resistente dos 4-amino-quinoleínicos. Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo1984-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/87273Revista do Instituto de Medicina Tropical de São Paulo; Vol. 26 No. 3 (1984); 139-146Revista do Instituto de Medicina Tropical de São Paulo; Vol. 26 Núm. 3 (1984); 139-146Revista do Instituto de Medicina Tropical de São Paulo; v. 26 n. 3 (1984); 139-1461678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTporhttps://www.revistas.usp.br/rimtsp/article/view/87273/90235Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessSilva, A. Rafael DaCarneiro, Ernane Wilson BezerraSantos, Henrique Jorge Dos2014-11-07T12:02:00Zoai:revistas.usp.br:article/87273Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:52:20.560343Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true
dc.title.none.fl_str_mv Response of human Plasmodium to antimalarial Drugs in S. Luis, Maranhão State, Brazil
Resposta dos plasmódios humanos aos antimaláricos na ilha de São Luís, estado do Maranhão, Brasil
title Response of human Plasmodium to antimalarial Drugs in S. Luis, Maranhão State, Brazil
spellingShingle Response of human Plasmodium to antimalarial Drugs in S. Luis, Maranhão State, Brazil
Silva, A. Rafael Da
title_short Response of human Plasmodium to antimalarial Drugs in S. Luis, Maranhão State, Brazil
title_full Response of human Plasmodium to antimalarial Drugs in S. Luis, Maranhão State, Brazil
title_fullStr Response of human Plasmodium to antimalarial Drugs in S. Luis, Maranhão State, Brazil
title_full_unstemmed Response of human Plasmodium to antimalarial Drugs in S. Luis, Maranhão State, Brazil
title_sort Response of human Plasmodium to antimalarial Drugs in S. Luis, Maranhão State, Brazil
author Silva, A. Rafael Da
author_facet Silva, A. Rafael Da
Carneiro, Ernane Wilson Bezerra
Santos, Henrique Jorge Dos
author_role author
author2 Carneiro, Ernane Wilson Bezerra
Santos, Henrique Jorge Dos
author2_role author
author
dc.contributor.author.fl_str_mv Silva, A. Rafael Da
Carneiro, Ernane Wilson Bezerra
Santos, Henrique Jorge Dos
description The Authors studied the response of human PLASMODIUM "in vivo" to antimalarial drugs in São Luís, Maranhão State, Brazil, during the years of 1981 and 1982. In the treatment of Plasmodium falciparum malaria was shown that 25.9% presented resistance to chloroquine and 16% to the association sulfonamide and pyrimethamine. With Plasmodium vivax it was found that effectiveness was 94.4% and 96% for both regimens of treatment. Finally the Authors suggest the use of the association chloroquine, primaquine and pyrimetamine in a three days scheme for better and low cost treatment. Also the associations sulfonamide, pyrimetamine and quinine as an alternative treatment for Plasmodium falciparum resistant to 4-amino-quinolines.
publishDate 1984
dc.date.none.fl_str_mv 1984-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/87273
url https://www.revistas.usp.br/rimtsp/article/view/87273
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/87273/90235
dc.rights.driver.fl_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
dc.source.none.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo; Vol. 26 No. 3 (1984); 139-146
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 26 Núm. 3 (1984); 139-146
Revista do Instituto de Medicina Tropical de São Paulo; v. 26 n. 3 (1984); 139-146
1678-9946
0036-4665
reponame:Revista do Instituto de Medicina Tropical de São Paulo
instname:Instituto de Medicina Tropical (IMT)
instacron:IMT
instname_str Instituto de Medicina Tropical (IMT)
instacron_str IMT
institution IMT
reponame_str Revista do Instituto de Medicina Tropical de São Paulo
collection Revista do Instituto de Medicina Tropical de São Paulo
repository.name.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)
repository.mail.fl_str_mv ||revimtsp@usp.br
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