Molluscicidal effect of Euphorbia umbellata (Pax) Bruyns latex on Biomphalaria glabrata, Schistosoma mansoni host snail

Detalhes bibliográficos
Autor(a) principal: Pereira, Luciana Patrícia Lima Alves
Data de Publicação: 2017
Outros Autores: Dias, Clarice Noleto, Miranda, Milena Valadar, Firmo, Wellyson da Cunha Araújo, Rosa, Carliane dos Santos, Santos, Priscila Freitas, Brito, Maria Cristiane Aranha, Araruna, Fernanda Oliveira Sousa, Araruna, Felipe Bastos, Silva-Souza, Nêuton, Coutinho, Denise Fernandes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/143765
Resumo: Euphorbia umbellata (Pax) Bruyns is an easily cultivated shrub, with occurrence in the tropical regions of the American and African continents. Chemical studies have revealed that the latex of this plant is rich in terpene compounds, which are highly toxic to snails Biomphalaria glabrata (Basommatophora: Planorbidae). The aim of this study was to evaluate the chemical composition and molluscicidal activity of the latex produced by E. umbellata, as well as the safety of its application in aquatic environments. The concentration of latex that killed 90% of the exposed snails after 24 h exposure (LC90) was 3.69 mg/L. Toxicity bioassays using Danio rerio (zebrafish) revealed that these animals were less susceptible to latex than planorbids. However, it is important to perform other toxicity tests to ensure the feasibility of using latex to control populations of mollusks that contribute to schistosomiasis transmission. A phytochemical screening performed with the E. umbellata latex identified the triterpenoid and coumarin class. Further studies are warranted to isolate, identify, and test the active compounds of E. umbellata latex in B. glabrata.
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spelling Molluscicidal effect of Euphorbia umbellata (Pax) Bruyns latex on Biomphalaria glabrata, Schistosoma mansoni host snailPlant productToxicityBiomphalaria glabrataSchistosomiasisSchistosoma mansoniMolluscicidal effectEuphorbia umbellata (Pax) Bruyns is an easily cultivated shrub, with occurrence in the tropical regions of the American and African continents. Chemical studies have revealed that the latex of this plant is rich in terpene compounds, which are highly toxic to snails Biomphalaria glabrata (Basommatophora: Planorbidae). The aim of this study was to evaluate the chemical composition and molluscicidal activity of the latex produced by E. umbellata, as well as the safety of its application in aquatic environments. The concentration of latex that killed 90% of the exposed snails after 24 h exposure (LC90) was 3.69 mg/L. Toxicity bioassays using Danio rerio (zebrafish) revealed that these animals were less susceptible to latex than planorbids. However, it is important to perform other toxicity tests to ensure the feasibility of using latex to control populations of mollusks that contribute to schistosomiasis transmission. A phytochemical screening performed with the E. umbellata latex identified the triterpenoid and coumarin class. Further studies are warranted to isolate, identify, and test the active compounds of E. umbellata latex in B. glabrata.Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo2017-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/143765Revista do Instituto de Medicina Tropical de São Paulo; Vol. 59 (2017); e85Revista do Instituto de Medicina Tropical de São Paulo; Vol. 59 (2017); e85Revista do Instituto de Medicina Tropical de São Paulo; v. 59 (2017); e851678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/143765/138412Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessPereira, Luciana Patrícia Lima AlvesDias, Clarice NoletoMiranda, Milena ValadarFirmo, Wellyson da Cunha AraújoRosa, Carliane dos SantosSantos, Priscila FreitasBrito, Maria Cristiane AranhaAraruna, Fernanda Oliveira SousaAraruna, Felipe BastosSilva-Souza, NêutonCoutinho, Denise Fernandes2018-12-04T13:33:43Zoai:revistas.usp.br:article/143765Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:52:43.512774Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true
dc.title.none.fl_str_mv Molluscicidal effect of Euphorbia umbellata (Pax) Bruyns latex on Biomphalaria glabrata, Schistosoma mansoni host snail
title Molluscicidal effect of Euphorbia umbellata (Pax) Bruyns latex on Biomphalaria glabrata, Schistosoma mansoni host snail
spellingShingle Molluscicidal effect of Euphorbia umbellata (Pax) Bruyns latex on Biomphalaria glabrata, Schistosoma mansoni host snail
Pereira, Luciana Patrícia Lima Alves
Plant product
Toxicity
Biomphalaria glabrata
Schistosomiasis
Schistosoma mansoni
Molluscicidal effect
title_short Molluscicidal effect of Euphorbia umbellata (Pax) Bruyns latex on Biomphalaria glabrata, Schistosoma mansoni host snail
title_full Molluscicidal effect of Euphorbia umbellata (Pax) Bruyns latex on Biomphalaria glabrata, Schistosoma mansoni host snail
title_fullStr Molluscicidal effect of Euphorbia umbellata (Pax) Bruyns latex on Biomphalaria glabrata, Schistosoma mansoni host snail
title_full_unstemmed Molluscicidal effect of Euphorbia umbellata (Pax) Bruyns latex on Biomphalaria glabrata, Schistosoma mansoni host snail
title_sort Molluscicidal effect of Euphorbia umbellata (Pax) Bruyns latex on Biomphalaria glabrata, Schistosoma mansoni host snail
author Pereira, Luciana Patrícia Lima Alves
author_facet Pereira, Luciana Patrícia Lima Alves
Dias, Clarice Noleto
Miranda, Milena Valadar
Firmo, Wellyson da Cunha Araújo
Rosa, Carliane dos Santos
Santos, Priscila Freitas
Brito, Maria Cristiane Aranha
Araruna, Fernanda Oliveira Sousa
Araruna, Felipe Bastos
Silva-Souza, Nêuton
Coutinho, Denise Fernandes
author_role author
author2 Dias, Clarice Noleto
Miranda, Milena Valadar
Firmo, Wellyson da Cunha Araújo
Rosa, Carliane dos Santos
Santos, Priscila Freitas
Brito, Maria Cristiane Aranha
Araruna, Fernanda Oliveira Sousa
Araruna, Felipe Bastos
Silva-Souza, Nêuton
Coutinho, Denise Fernandes
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Pereira, Luciana Patrícia Lima Alves
Dias, Clarice Noleto
Miranda, Milena Valadar
Firmo, Wellyson da Cunha Araújo
Rosa, Carliane dos Santos
Santos, Priscila Freitas
Brito, Maria Cristiane Aranha
Araruna, Fernanda Oliveira Sousa
Araruna, Felipe Bastos
Silva-Souza, Nêuton
Coutinho, Denise Fernandes
dc.subject.por.fl_str_mv Plant product
Toxicity
Biomphalaria glabrata
Schistosomiasis
Schistosoma mansoni
Molluscicidal effect
topic Plant product
Toxicity
Biomphalaria glabrata
Schistosomiasis
Schistosoma mansoni
Molluscicidal effect
description Euphorbia umbellata (Pax) Bruyns is an easily cultivated shrub, with occurrence in the tropical regions of the American and African continents. Chemical studies have revealed that the latex of this plant is rich in terpene compounds, which are highly toxic to snails Biomphalaria glabrata (Basommatophora: Planorbidae). The aim of this study was to evaluate the chemical composition and molluscicidal activity of the latex produced by E. umbellata, as well as the safety of its application in aquatic environments. The concentration of latex that killed 90% of the exposed snails after 24 h exposure (LC90) was 3.69 mg/L. Toxicity bioassays using Danio rerio (zebrafish) revealed that these animals were less susceptible to latex than planorbids. However, it is important to perform other toxicity tests to ensure the feasibility of using latex to control populations of mollusks that contribute to schistosomiasis transmission. A phytochemical screening performed with the E. umbellata latex identified the triterpenoid and coumarin class. Further studies are warranted to isolate, identify, and test the active compounds of E. umbellata latex in B. glabrata.
publishDate 2017
dc.date.none.fl_str_mv 2017-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/143765
url https://www.revistas.usp.br/rimtsp/article/view/143765
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/143765/138412
dc.rights.driver.fl_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
dc.source.none.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo; Vol. 59 (2017); e85
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 59 (2017); e85
Revista do Instituto de Medicina Tropical de São Paulo; v. 59 (2017); e85
1678-9946
0036-4665
reponame:Revista do Instituto de Medicina Tropical de São Paulo
instname:Instituto de Medicina Tropical (IMT)
instacron:IMT
instname_str Instituto de Medicina Tropical (IMT)
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institution IMT
reponame_str Revista do Instituto de Medicina Tropical de São Paulo
collection Revista do Instituto de Medicina Tropical de São Paulo
repository.name.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)
repository.mail.fl_str_mv ||revimtsp@usp.br
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