The effect of chronic ingestion of ethanol on modulation of granulomatous inflammation in experimental schistosomiasis in mice

Detalhes bibliográficos
Autor(a) principal: Castro, L.P.F.
Data de Publicação: 1993
Outros Autores: Bambirra, E.A., Coelho, P.M.Z., Silva, M.E.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/29074
Resumo: We studied the role of ethanol on the modulation of liver granulomata around Schistosoma mansoni eggs in mice. Albino mice, receiving 7% ethanol as the sole drinking liquid, at 60 and 90 days post-infection, presented smaller granulomata than controls did, when sacrificed at 120 days post-infection. No differences in diameters could be observed, when ethanol was given 4 months before up to 120 days after infection. The results suggested that modulation of schistosome granulomata by ethanol ingestion varies with time and duration of drug consumption.
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spelling The effect of chronic ingestion of ethanol on modulation of granulomatous inflammation in experimental schistosomiasis in mice Efeito da ingestão crônica de etanol na modulação da resposta inflamatória granulomatosa no fígado de camundongos infectados por Schistosoma mansoni Schistosomiasis mansoniEthanolModulation of granulomatous inflammation We studied the role of ethanol on the modulation of liver granulomata around Schistosoma mansoni eggs in mice. Albino mice, receiving 7% ethanol as the sole drinking liquid, at 60 and 90 days post-infection, presented smaller granulomata than controls did, when sacrificed at 120 days post-infection. No differences in diameters could be observed, when ethanol was given 4 months before up to 120 days after infection. The results suggested that modulation of schistosome granulomata by ethanol ingestion varies with time and duration of drug consumption. Estudamos a modulação da resposta inflamatória granulomatosa em torno de ovos de S. mansoni no fígado de camundongos albinos (Mus musculus), que receberam 7% de etanol como única fonte de líquido. Os animais que receberam etanol aos 60 e 90 dias após a infecção apresentaram granulomas menores do que os controles, quando sacrificados aos 120 dias após a infecção. Não houve diferença no diâmetro dos granulomas quando a ingestão de etanol foi iniciada 4 meses antes e prolongada até 120 dias após a infecção. Nossos resultados indicam que a modulação da inflamação granulomatosa varia de acordo com o tempo e a duração da ingestão do etanol. Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo1993-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/29074Revista do Instituto de Medicina Tropical de São Paulo; Vol. 35 No. 5 (1993); 391-394 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 35 Núm. 5 (1993); 391-394 Revista do Instituto de Medicina Tropical de São Paulo; v. 35 n. 5 (1993); 391-394 1678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/29074/30931Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessCastro, L.P.F.Bambirra, E.A.Coelho, P.M.Z.Silva, M.E.2012-07-02T01:36:00Zoai:revistas.usp.br:article/29074Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:50:49.889497Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true
dc.title.none.fl_str_mv The effect of chronic ingestion of ethanol on modulation of granulomatous inflammation in experimental schistosomiasis in mice
Efeito da ingestão crônica de etanol na modulação da resposta inflamatória granulomatosa no fígado de camundongos infectados por Schistosoma mansoni
title The effect of chronic ingestion of ethanol on modulation of granulomatous inflammation in experimental schistosomiasis in mice
spellingShingle The effect of chronic ingestion of ethanol on modulation of granulomatous inflammation in experimental schistosomiasis in mice
Castro, L.P.F.
Schistosomiasis mansoni
Ethanol
Modulation of granulomatous inflammation
title_short The effect of chronic ingestion of ethanol on modulation of granulomatous inflammation in experimental schistosomiasis in mice
title_full The effect of chronic ingestion of ethanol on modulation of granulomatous inflammation in experimental schistosomiasis in mice
title_fullStr The effect of chronic ingestion of ethanol on modulation of granulomatous inflammation in experimental schistosomiasis in mice
title_full_unstemmed The effect of chronic ingestion of ethanol on modulation of granulomatous inflammation in experimental schistosomiasis in mice
title_sort The effect of chronic ingestion of ethanol on modulation of granulomatous inflammation in experimental schistosomiasis in mice
author Castro, L.P.F.
author_facet Castro, L.P.F.
Bambirra, E.A.
Coelho, P.M.Z.
Silva, M.E.
author_role author
author2 Bambirra, E.A.
Coelho, P.M.Z.
Silva, M.E.
author2_role author
author
author
dc.contributor.author.fl_str_mv Castro, L.P.F.
Bambirra, E.A.
Coelho, P.M.Z.
Silva, M.E.
dc.subject.por.fl_str_mv Schistosomiasis mansoni
Ethanol
Modulation of granulomatous inflammation
topic Schistosomiasis mansoni
Ethanol
Modulation of granulomatous inflammation
description We studied the role of ethanol on the modulation of liver granulomata around Schistosoma mansoni eggs in mice. Albino mice, receiving 7% ethanol as the sole drinking liquid, at 60 and 90 days post-infection, presented smaller granulomata than controls did, when sacrificed at 120 days post-infection. No differences in diameters could be observed, when ethanol was given 4 months before up to 120 days after infection. The results suggested that modulation of schistosome granulomata by ethanol ingestion varies with time and duration of drug consumption.
publishDate 1993
dc.date.none.fl_str_mv 1993-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/29074
url https://www.revistas.usp.br/rimtsp/article/view/29074
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/29074/30931
dc.rights.driver.fl_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
dc.source.none.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo; Vol. 35 No. 5 (1993); 391-394
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 35 Núm. 5 (1993); 391-394
Revista do Instituto de Medicina Tropical de São Paulo; v. 35 n. 5 (1993); 391-394
1678-9946
0036-4665
reponame:Revista do Instituto de Medicina Tropical de São Paulo
instname:Instituto de Medicina Tropical (IMT)
instacron:IMT
instname_str Instituto de Medicina Tropical (IMT)
instacron_str IMT
institution IMT
reponame_str Revista do Instituto de Medicina Tropical de São Paulo
collection Revista do Instituto de Medicina Tropical de São Paulo
repository.name.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)
repository.mail.fl_str_mv ||revimtsp@usp.br
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