Unusual presentation of a disseminated oral HPV infection after combined antiretroviral therapy initiation

• Autor(a) principal: Vale, Daniela Assis do
• Data de Publicação: 2019
• Outros Autores: Ferracini, Lais Magda Araújo, Bueno, Marcus Vinícius da Silva Rodrigues, Souza, Ana Carolina Mamana Fernandes, Braz-Silva, Paulo Henrique, Ortega, Karem López
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
• Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/163050
• topic: HIV; HPV; Condyloma acuminate; Focal epithelial hyperplasia

HIVHPV clinical manifestations have their characteristics modified by the use of combined antiretroviral therapy (cART), although its incidence is unaffected by cART. We report an unusual presentation of oral HPV infection and discuss an effective treatment for disseminated HPV lesions. A 52-year-old male of Asian-origin, HIV-seropositive, presented with extensive nodular lesions throughout the oral mucosa extending to the oropharyngeal region. Biopsy followed by histopathological examination and HPV genotyping were performed. The treatment was initiated with topical application of podophyllin and trichloroacetic acid. HPV lesions in oral mucosa are generally easy to handle. Extensive lesions can make it difficult to choose an effective treatment that meets the patient’s particularities and medication availability.