First case report of atypical disseminated cutaneous leishmaniasis in an opium abuser in Iran
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista do Instituto de Medicina Tropical de São Paulo |
Texto Completo: | https://www.revistas.usp.br/rimtsp/article/view/143482 |
Resumo: | Leishmaniasis is a worldwide tropical infectious disease caused by different species of intracellular protozoa parasites of the genus Leishmania . Herein, we report a 78-year-old man with unusual diffuse cutaneous leishmaniasis (DCL) who had a history of opium abuse and chronic obstructive pulmonary disease (COPD). He had multiple papular, crusted and severely ulcerated lesions extended to his arm and chest. Direct smears and skin punch biopsy of the lesions were suggestive of leishmaniasis. Parasite DNA was amplified from ulcers, and identified as Leishmania major by PCR-RFLP, confirmed by sequencing analyses. The aim of the current study was to bring to attention this atypical form of disease in CL endemic countries. Thus, this is the first case of DCL in an opium abuser with COPD due to L. major in Northeastern Iran indicating that atypical and extensive forms of CL (DCL) owing to L. major are increasing in Iran. |
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First case report of atypical disseminated cutaneous leishmaniasis in an opium abuser in IranDCLOpiumL. majorLeishmaniasisCOPDPCR-RFLPIran Leishmaniasis is a worldwide tropical infectious disease caused by different species of intracellular protozoa parasites of the genus Leishmania . Herein, we report a 78-year-old man with unusual diffuse cutaneous leishmaniasis (DCL) who had a history of opium abuse and chronic obstructive pulmonary disease (COPD). He had multiple papular, crusted and severely ulcerated lesions extended to his arm and chest. Direct smears and skin punch biopsy of the lesions were suggestive of leishmaniasis. Parasite DNA was amplified from ulcers, and identified as Leishmania major by PCR-RFLP, confirmed by sequencing analyses. The aim of the current study was to bring to attention this atypical form of disease in CL endemic countries. Thus, this is the first case of DCL in an opium abuser with COPD due to L. major in Northeastern Iran indicating that atypical and extensive forms of CL (DCL) owing to L. major are increasing in Iran.Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo2018-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/xmlhttps://www.revistas.usp.br/rimtsp/article/view/143482Revista do Instituto de Medicina Tropical de São Paulo; Vol. 60 (2018); e5Revista do Instituto de Medicina Tropical de São Paulo; Vol. 60 (2018); e5Revista do Instituto de Medicina Tropical de São Paulo; v. 60 (2018); e51678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/143482/138161https://www.revistas.usp.br/rimtsp/article/view/143482/148508Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessHashemi, Seyed AhmadBadirzadeh, AlirezaSabzevari, SadafNouri, AliSeyyedin, Mohammad2018-07-12T16:41:33Zoai:revistas.usp.br:article/143482Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:52:42.327107Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true |
dc.title.none.fl_str_mv |
First case report of atypical disseminated cutaneous leishmaniasis in an opium abuser in Iran |
title |
First case report of atypical disseminated cutaneous leishmaniasis in an opium abuser in Iran |
spellingShingle |
First case report of atypical disseminated cutaneous leishmaniasis in an opium abuser in Iran Hashemi, Seyed Ahmad DCL Opium L. major Leishmaniasis COPD PCR-RFLP Iran |
title_short |
First case report of atypical disseminated cutaneous leishmaniasis in an opium abuser in Iran |
title_full |
First case report of atypical disseminated cutaneous leishmaniasis in an opium abuser in Iran |
title_fullStr |
First case report of atypical disseminated cutaneous leishmaniasis in an opium abuser in Iran |
title_full_unstemmed |
First case report of atypical disseminated cutaneous leishmaniasis in an opium abuser in Iran |
title_sort |
First case report of atypical disseminated cutaneous leishmaniasis in an opium abuser in Iran |
author |
Hashemi, Seyed Ahmad |
author_facet |
Hashemi, Seyed Ahmad Badirzadeh, Alireza Sabzevari, Sadaf Nouri, Ali Seyyedin, Mohammad |
author_role |
author |
author2 |
Badirzadeh, Alireza Sabzevari, Sadaf Nouri, Ali Seyyedin, Mohammad |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Hashemi, Seyed Ahmad Badirzadeh, Alireza Sabzevari, Sadaf Nouri, Ali Seyyedin, Mohammad |
dc.subject.por.fl_str_mv |
DCL Opium L. major Leishmaniasis COPD PCR-RFLP Iran |
topic |
DCL Opium L. major Leishmaniasis COPD PCR-RFLP Iran |
description |
Leishmaniasis is a worldwide tropical infectious disease caused by different species of intracellular protozoa parasites of the genus Leishmania . Herein, we report a 78-year-old man with unusual diffuse cutaneous leishmaniasis (DCL) who had a history of opium abuse and chronic obstructive pulmonary disease (COPD). He had multiple papular, crusted and severely ulcerated lesions extended to his arm and chest. Direct smears and skin punch biopsy of the lesions were suggestive of leishmaniasis. Parasite DNA was amplified from ulcers, and identified as Leishmania major by PCR-RFLP, confirmed by sequencing analyses. The aim of the current study was to bring to attention this atypical form of disease in CL endemic countries. Thus, this is the first case of DCL in an opium abuser with COPD due to L. major in Northeastern Iran indicating that atypical and extensive forms of CL (DCL) owing to L. major are increasing in Iran. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/143482 |
url |
https://www.revistas.usp.br/rimtsp/article/view/143482 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/143482/138161 https://www.revistas.usp.br/rimtsp/article/view/143482/148508 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/xml |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
dc.source.none.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 60 (2018); e5 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 60 (2018); e5 Revista do Instituto de Medicina Tropical de São Paulo; v. 60 (2018); e5 1678-9946 0036-4665 reponame:Revista do Instituto de Medicina Tropical de São Paulo instname:Instituto de Medicina Tropical (IMT) instacron:IMT |
instname_str |
Instituto de Medicina Tropical (IMT) |
instacron_str |
IMT |
institution |
IMT |
reponame_str |
Revista do Instituto de Medicina Tropical de São Paulo |
collection |
Revista do Instituto de Medicina Tropical de São Paulo |
repository.name.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT) |
repository.mail.fl_str_mv |
||revimtsp@usp.br |
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1798951651770368000 |