New records of Histoplasma capsulatum from wild animals in the Brazilian Amazon
Autor(a) principal: | |
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Data de Publicação: | 1996 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista do Instituto de Medicina Tropical de São Paulo |
Texto Completo: | https://www.revistas.usp.br/rimtsp/article/view/29382 |
Resumo: | Twenty-eight isolates of Histoplasma capsulation were obtained from eight species of forest mammals from the States of Amazonas, Pará and Rondônia in the Amazon Region of Brazil. Primary isolates were obtained by inoculating triturated liver and spleen tissue intradermally and intraperito-neally in hamsters. Mycological diagnosis in hamsters presenting lesions was confirmed by histopathology and culture on Sabouraud dextrose-agar. Infected hamsters developed signs of disease within two to nine months; all had disseminated visceral lesions and most also had skin lesions at the sites of inoculation. None of the hamsters inoculated with skin macerates of the original hosts developed histoplasmosis, and histopathological examination of the viscera of the wild hosts failed to reveal H. capsulation. Prevalence of infection was considerably higher in females than in males both for the opossum Didelphis marsupialis and for total wild animals (479) examined. It is proposed that canopy-dwelling mammals may acquire the infection from conidia borne on convective currents in hollow trees with openings at ground-level. |
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New records of Histoplasma capsulatum from wild animals in the Brazilian Amazon Novos registros de Histoplasma capsulatum em animais silvestres na Amazônia brasileira Enzootic histoplasmosisSex-related prevalenceAmazon Basin Twenty-eight isolates of Histoplasma capsulation were obtained from eight species of forest mammals from the States of Amazonas, Pará and Rondônia in the Amazon Region of Brazil. Primary isolates were obtained by inoculating triturated liver and spleen tissue intradermally and intraperito-neally in hamsters. Mycological diagnosis in hamsters presenting lesions was confirmed by histopathology and culture on Sabouraud dextrose-agar. Infected hamsters developed signs of disease within two to nine months; all had disseminated visceral lesions and most also had skin lesions at the sites of inoculation. None of the hamsters inoculated with skin macerates of the original hosts developed histoplasmosis, and histopathological examination of the viscera of the wild hosts failed to reveal H. capsulation. Prevalence of infection was considerably higher in females than in males both for the opossum Didelphis marsupialis and for total wild animals (479) examined. It is proposed that canopy-dwelling mammals may acquire the infection from conidia borne on convective currents in hollow trees with openings at ground-level. Vinte e oito amostras de Histoplasma capsulatum foram obtidas de oito espécies de mamíferos silvestres nos Estados do Amazonas, Pará e Rondônia. Os isolamentos foram feitos mediante inoculação de amostras trituradas de fígado e baço em hamsters por via intradérmica e intraperitoneal. O diagnóstico micológico nos hamsters que apresentaram lesões foi confirmado por histopatologia e cultivo em meio dextrose-agar de Sabouraud. Os hamsters infectados desenvolveram sinais de doença após dois a nove meses; todos apresentaram lesões disseminadas nas vísceras e a maioria apresentou também lesões cutâneas nos locais da inoculação. Nenhum dos hamsters inoculados com material de pele dos hospedeiros originais desenvolveu histoplasmose, e H. capsulatum não foi detectado nos exames histopatológicos dos animais silvestres. A prevalência de infecção foi consideravelmente mais alta entre fêmeas, tanto para Didelphis marsupialis como para o total de animais silvestres examinados (479). Propõe-se que as infecções detectadas em animais arborícolas podem ser explicadas pelo transporte de esporos do fungo em correntezas convectivas dentro de árvores ocas que tenham uma abertura ao nível do solo e outra a nível proximo das copas. Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo1996-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/29382Revista do Instituto de Medicina Tropical de São Paulo; Vol. 38 No. 4 (1996); 273-278 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 38 Núm. 4 (1996); 273-278 Revista do Instituto de Medicina Tropical de São Paulo; v. 38 n. 4 (1996); 273-278 1678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/29382/31239Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessNaiff, Roberto DaibesBarrett, Toby VincentNaiff, Maricleide de FariasFerreira, Luiz Carlos de LimaRamon Arias, Jorge2012-07-02T01:43:51Zoai:revistas.usp.br:article/29382Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:51:07.784432Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true |
dc.title.none.fl_str_mv |
New records of Histoplasma capsulatum from wild animals in the Brazilian Amazon Novos registros de Histoplasma capsulatum em animais silvestres na Amazônia brasileira |
title |
New records of Histoplasma capsulatum from wild animals in the Brazilian Amazon |
spellingShingle |
New records of Histoplasma capsulatum from wild animals in the Brazilian Amazon Naiff, Roberto Daibes Enzootic histoplasmosis Sex-related prevalence Amazon Basin |
title_short |
New records of Histoplasma capsulatum from wild animals in the Brazilian Amazon |
title_full |
New records of Histoplasma capsulatum from wild animals in the Brazilian Amazon |
title_fullStr |
New records of Histoplasma capsulatum from wild animals in the Brazilian Amazon |
title_full_unstemmed |
New records of Histoplasma capsulatum from wild animals in the Brazilian Amazon |
title_sort |
New records of Histoplasma capsulatum from wild animals in the Brazilian Amazon |
author |
Naiff, Roberto Daibes |
author_facet |
Naiff, Roberto Daibes Barrett, Toby Vincent Naiff, Maricleide de Farias Ferreira, Luiz Carlos de Lima Ramon Arias, Jorge |
author_role |
author |
author2 |
Barrett, Toby Vincent Naiff, Maricleide de Farias Ferreira, Luiz Carlos de Lima Ramon Arias, Jorge |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Naiff, Roberto Daibes Barrett, Toby Vincent Naiff, Maricleide de Farias Ferreira, Luiz Carlos de Lima Ramon Arias, Jorge |
dc.subject.por.fl_str_mv |
Enzootic histoplasmosis Sex-related prevalence Amazon Basin |
topic |
Enzootic histoplasmosis Sex-related prevalence Amazon Basin |
description |
Twenty-eight isolates of Histoplasma capsulation were obtained from eight species of forest mammals from the States of Amazonas, Pará and Rondônia in the Amazon Region of Brazil. Primary isolates were obtained by inoculating triturated liver and spleen tissue intradermally and intraperito-neally in hamsters. Mycological diagnosis in hamsters presenting lesions was confirmed by histopathology and culture on Sabouraud dextrose-agar. Infected hamsters developed signs of disease within two to nine months; all had disseminated visceral lesions and most also had skin lesions at the sites of inoculation. None of the hamsters inoculated with skin macerates of the original hosts developed histoplasmosis, and histopathological examination of the viscera of the wild hosts failed to reveal H. capsulation. Prevalence of infection was considerably higher in females than in males both for the opossum Didelphis marsupialis and for total wild animals (479) examined. It is proposed that canopy-dwelling mammals may acquire the infection from conidia borne on convective currents in hollow trees with openings at ground-level. |
publishDate |
1996 |
dc.date.none.fl_str_mv |
1996-08-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/29382 |
url |
https://www.revistas.usp.br/rimtsp/article/view/29382 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/29382/31239 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
dc.source.none.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 38 No. 4 (1996); 273-278 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 38 Núm. 4 (1996); 273-278 Revista do Instituto de Medicina Tropical de São Paulo; v. 38 n. 4 (1996); 273-278 1678-9946 0036-4665 reponame:Revista do Instituto de Medicina Tropical de São Paulo instname:Instituto de Medicina Tropical (IMT) instacron:IMT |
instname_str |
Instituto de Medicina Tropical (IMT) |
instacron_str |
IMT |
institution |
IMT |
reponame_str |
Revista do Instituto de Medicina Tropical de São Paulo |
collection |
Revista do Instituto de Medicina Tropical de São Paulo |
repository.name.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT) |
repository.mail.fl_str_mv |
||revimtsp@usp.br |
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