Prevalence of Hepatitis B and C virus infection among alcoholic individuals: importance of screening and vaccination
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista do Instituto de Medicina Tropical de São Paulo |
Texto Completo: | https://www.revistas.usp.br/rimtsp/article/view/140667 |
Resumo: | Drug users have been reported to have an increased risk for acquisition of viral hepatitis. This study aims to evaluate the prevalence of HBV and HCV infection and usefulness of saliva for HBsAg and anti-HCV detection in alcoholic patients.A total of 90 alcoholic patients were recruited in 2013. HBsAg and anti-HCV were tested in serum and saliva, anti-HBc and anti-HBs were tested in serum using commercial enzyme immunoassays (EIA).Using serum samples, anti-HCV, HBsAg, anti-HBc and anti-HBs prevalences were 5.6%, 0%, 15.7%, and 29.2%. HBsAg detection in saliva showed 100% of specificity and anti-HCV detection demonstrated 100% of sensitivity and 94.7% of specificity. Low prevalence of HBV and high prevalence of anti-HCV were found and reinforced the recommendation of HBV vaccination to avoid the acute and chronic cases and HCV screening in this group to identify cases for antiviral therapy. Saliva samples could be used for anti-HCV detection in this population, what could increase the diagnosis access. |
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Prevalence of Hepatitis B and C virus infection among alcoholic individuals: importance of screening and vaccinationHepatitis C virus Hepatitis B virusPrevalenceSalivaAlcoholic patients Drug users have been reported to have an increased risk for acquisition of viral hepatitis. This study aims to evaluate the prevalence of HBV and HCV infection and usefulness of saliva for HBsAg and anti-HCV detection in alcoholic patients.A total of 90 alcoholic patients were recruited in 2013. HBsAg and anti-HCV were tested in serum and saliva, anti-HBc and anti-HBs were tested in serum using commercial enzyme immunoassays (EIA).Using serum samples, anti-HCV, HBsAg, anti-HBc and anti-HBs prevalences were 5.6%, 0%, 15.7%, and 29.2%. HBsAg detection in saliva showed 100% of specificity and anti-HCV detection demonstrated 100% of sensitivity and 94.7% of specificity. Low prevalence of HBV and high prevalence of anti-HCV were found and reinforced the recommendation of HBV vaccination to avoid the acute and chronic cases and HCV screening in this group to identify cases for antiviral therapy. Saliva samples could be used for anti-HCV detection in this population, what could increase the diagnosis access.Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo2017-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/xmlhttps://www.revistas.usp.br/rimtsp/article/view/140667Revista do Instituto de Medicina Tropical de São Paulo; Vol. 59 (2017); e47Revista do Instituto de Medicina Tropical de São Paulo; Vol. 59 (2017); e47Revista do Instituto de Medicina Tropical de São Paulo; v. 59 (2017); e471678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/140667/135630https://www.revistas.usp.br/rimtsp/article/view/140667/147938Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessCortes, Vanessa FariaTaveira, AngelaCruz, Helena MedinaReis, Amanda AlvesCezar, Jéssica SilvaSilva, Brener SantosD’Assunção, Cintia FelicianoLampe, ElisabethVillar, Livia Melo2018-02-23T18:46:01Zoai:revistas.usp.br:article/140667Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:52:40.230423Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true |
dc.title.none.fl_str_mv |
Prevalence of Hepatitis B and C virus infection among alcoholic individuals: importance of screening and vaccination |
title |
Prevalence of Hepatitis B and C virus infection among alcoholic individuals: importance of screening and vaccination |
spellingShingle |
Prevalence of Hepatitis B and C virus infection among alcoholic individuals: importance of screening and vaccination Cortes, Vanessa Faria Hepatitis C virus Hepatitis B virus Prevalence Saliva Alcoholic patients |
title_short |
Prevalence of Hepatitis B and C virus infection among alcoholic individuals: importance of screening and vaccination |
title_full |
Prevalence of Hepatitis B and C virus infection among alcoholic individuals: importance of screening and vaccination |
title_fullStr |
Prevalence of Hepatitis B and C virus infection among alcoholic individuals: importance of screening and vaccination |
title_full_unstemmed |
Prevalence of Hepatitis B and C virus infection among alcoholic individuals: importance of screening and vaccination |
title_sort |
Prevalence of Hepatitis B and C virus infection among alcoholic individuals: importance of screening and vaccination |
author |
Cortes, Vanessa Faria |
author_facet |
Cortes, Vanessa Faria Taveira, Angela Cruz, Helena Medina Reis, Amanda Alves Cezar, Jéssica Silva Silva, Brener Santos D’Assunção, Cintia Feliciano Lampe, Elisabeth Villar, Livia Melo |
author_role |
author |
author2 |
Taveira, Angela Cruz, Helena Medina Reis, Amanda Alves Cezar, Jéssica Silva Silva, Brener Santos D’Assunção, Cintia Feliciano Lampe, Elisabeth Villar, Livia Melo |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Cortes, Vanessa Faria Taveira, Angela Cruz, Helena Medina Reis, Amanda Alves Cezar, Jéssica Silva Silva, Brener Santos D’Assunção, Cintia Feliciano Lampe, Elisabeth Villar, Livia Melo |
dc.subject.por.fl_str_mv |
Hepatitis C virus Hepatitis B virus Prevalence Saliva Alcoholic patients |
topic |
Hepatitis C virus Hepatitis B virus Prevalence Saliva Alcoholic patients |
description |
Drug users have been reported to have an increased risk for acquisition of viral hepatitis. This study aims to evaluate the prevalence of HBV and HCV infection and usefulness of saliva for HBsAg and anti-HCV detection in alcoholic patients.A total of 90 alcoholic patients were recruited in 2013. HBsAg and anti-HCV were tested in serum and saliva, anti-HBc and anti-HBs were tested in serum using commercial enzyme immunoassays (EIA).Using serum samples, anti-HCV, HBsAg, anti-HBc and anti-HBs prevalences were 5.6%, 0%, 15.7%, and 29.2%. HBsAg detection in saliva showed 100% of specificity and anti-HCV detection demonstrated 100% of sensitivity and 94.7% of specificity. Low prevalence of HBV and high prevalence of anti-HCV were found and reinforced the recommendation of HBV vaccination to avoid the acute and chronic cases and HCV screening in this group to identify cases for antiviral therapy. Saliva samples could be used for anti-HCV detection in this population, what could increase the diagnosis access. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/140667 |
url |
https://www.revistas.usp.br/rimtsp/article/view/140667 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/rimtsp/article/view/140667/135630 https://www.revistas.usp.br/rimtsp/article/view/140667/147938 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/xml |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
publisher.none.fl_str_mv |
Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo |
dc.source.none.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 59 (2017); e47 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 59 (2017); e47 Revista do Instituto de Medicina Tropical de São Paulo; v. 59 (2017); e47 1678-9946 0036-4665 reponame:Revista do Instituto de Medicina Tropical de São Paulo instname:Instituto de Medicina Tropical (IMT) instacron:IMT |
instname_str |
Instituto de Medicina Tropical (IMT) |
instacron_str |
IMT |
institution |
IMT |
reponame_str |
Revista do Instituto de Medicina Tropical de São Paulo |
collection |
Revista do Instituto de Medicina Tropical de São Paulo |
repository.name.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT) |
repository.mail.fl_str_mv |
||revimtsp@usp.br |
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1798951651705356288 |