Evidences against a significant role of Mus musculus as natural host for Angiostrongylus costaricensis

Detalhes bibliográficos
Autor(a) principal: Santos, Fernanda Teixeira dos
Data de Publicação: 1996
Outros Autores: Pinto, Viviane M., Graeff-Teixeira, Carlos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/29357
Resumo: Wild rodents have been described as the most important hosts for Angiostrongylus costaricensis in Central America and southern Brazil. Sinantropic rodents apparently do not play a significant role as natural hosts. A search for natural infection failed to document worms in 14 mice captured in the house of a patient with diagnosis of abdominal angiostrongylosis and experimental infection of a "wild" Mus musculus strain and groups of albino Swiss mice were carried out. Mortality was not significantly different and varied from 42% to 80% for Swiss mice and from 26% to 80% for "wild" mice. The high mortality of a "wild" M. musculus infected with A. costaricensis was very similar to what is observed with most laboratory mice strains. These data may be taken as indications that M. musculus is not a well adapted host for A. costaricensis, although susceptibility was apparently higher with "wild" populations of M. musculus as compared to Swiss strain.
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spelling Evidences against a significant role of Mus musculus as natural host for Angiostrongylus costaricensis Evidências contrárias a um papel significativo de Mus musculus como hospedeiro natural do Angiostrongylus costaricensis Angiostrongylus costaricensisMus musculusAngiostrongylosis Wild rodents have been described as the most important hosts for Angiostrongylus costaricensis in Central America and southern Brazil. Sinantropic rodents apparently do not play a significant role as natural hosts. A search for natural infection failed to document worms in 14 mice captured in the house of a patient with diagnosis of abdominal angiostrongylosis and experimental infection of a "wild" Mus musculus strain and groups of albino Swiss mice were carried out. Mortality was not significantly different and varied from 42% to 80% for Swiss mice and from 26% to 80% for "wild" mice. The high mortality of a "wild" M. musculus infected with A. costaricensis was very similar to what is observed with most laboratory mice strains. These data may be taken as indications that M. musculus is not a well adapted host for A. costaricensis, although susceptibility was apparently higher with "wild" populations of M. musculus as compared to Swiss strain. Roedores silvestres tem sido descritos como os hospedeiros mais importantes do Angiostrongylus costaricensis na América Central e no Brasil. Roedores sinantrópicos aparentemente não desempenham um papel significativo como hospedeiros naturais. Relata-se a pesquisa negativa para infecção em 14 camundongos capturados na casa de um doente com diagnóstico de angiostrongilose abdominal e dados da infecção experimental de animais de uma cepa "natural" de Mus musculus e de camundongos albinos Swiss. Não houve diferença significativa de mortalidade, que variou entre 42% e 80% para a cepa Swiss e 26% e 80% para a cepa " natural" (RGS). A alta mortalidade dos camundongos RGS infectados com A. costaricensis foi semelhante ao que é observado com várias cepas de laboratório. Estes dados podem ser tornados como indicações de que Mus musculus não é hospedeiro bem adaptado ao A. costaricensis, embora a susceptibilidade de camundongos "naturais" pareça ser maior, quando comparados com a cepa Swiss. Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo1996-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rimtsp/article/view/29357Revista do Instituto de Medicina Tropical de São Paulo; Vol. 38 No. 3 (1996); 171-175 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 38 Núm. 3 (1996); 171-175 Revista do Instituto de Medicina Tropical de São Paulo; v. 38 n. 3 (1996); 171-175 1678-99460036-4665reponame:Revista do Instituto de Medicina Tropical de São Pauloinstname:Instituto de Medicina Tropical (IMT)instacron:IMTenghttps://www.revistas.usp.br/rimtsp/article/view/29357/31214Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessSantos, Fernanda Teixeira dosPinto, Viviane M.Graeff-Teixeira, Carlos2012-07-02T01:43:26Zoai:revistas.usp.br:article/29357Revistahttp://www.revistas.usp.br/rimtsp/indexPUBhttps://www.revistas.usp.br/rimtsp/oai||revimtsp@usp.br1678-99460036-4665opendoar:2022-12-13T16:51:06.339341Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)true
dc.title.none.fl_str_mv Evidences against a significant role of Mus musculus as natural host for Angiostrongylus costaricensis
Evidências contrárias a um papel significativo de Mus musculus como hospedeiro natural do Angiostrongylus costaricensis
title Evidences against a significant role of Mus musculus as natural host for Angiostrongylus costaricensis
spellingShingle Evidences against a significant role of Mus musculus as natural host for Angiostrongylus costaricensis
Santos, Fernanda Teixeira dos
Angiostrongylus costaricensis
Mus musculus
Angiostrongylosis
title_short Evidences against a significant role of Mus musculus as natural host for Angiostrongylus costaricensis
title_full Evidences against a significant role of Mus musculus as natural host for Angiostrongylus costaricensis
title_fullStr Evidences against a significant role of Mus musculus as natural host for Angiostrongylus costaricensis
title_full_unstemmed Evidences against a significant role of Mus musculus as natural host for Angiostrongylus costaricensis
title_sort Evidences against a significant role of Mus musculus as natural host for Angiostrongylus costaricensis
author Santos, Fernanda Teixeira dos
author_facet Santos, Fernanda Teixeira dos
Pinto, Viviane M.
Graeff-Teixeira, Carlos
author_role author
author2 Pinto, Viviane M.
Graeff-Teixeira, Carlos
author2_role author
author
dc.contributor.author.fl_str_mv Santos, Fernanda Teixeira dos
Pinto, Viviane M.
Graeff-Teixeira, Carlos
dc.subject.por.fl_str_mv Angiostrongylus costaricensis
Mus musculus
Angiostrongylosis
topic Angiostrongylus costaricensis
Mus musculus
Angiostrongylosis
description Wild rodents have been described as the most important hosts for Angiostrongylus costaricensis in Central America and southern Brazil. Sinantropic rodents apparently do not play a significant role as natural hosts. A search for natural infection failed to document worms in 14 mice captured in the house of a patient with diagnosis of abdominal angiostrongylosis and experimental infection of a "wild" Mus musculus strain and groups of albino Swiss mice were carried out. Mortality was not significantly different and varied from 42% to 80% for Swiss mice and from 26% to 80% for "wild" mice. The high mortality of a "wild" M. musculus infected with A. costaricensis was very similar to what is observed with most laboratory mice strains. These data may be taken as indications that M. musculus is not a well adapted host for A. costaricensis, although susceptibility was apparently higher with "wild" populations of M. musculus as compared to Swiss strain.
publishDate 1996
dc.date.none.fl_str_mv 1996-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/29357
url https://www.revistas.usp.br/rimtsp/article/view/29357
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rimtsp/article/view/29357/31214
dc.rights.driver.fl_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Revista do Instituto de Medicina Tropical de São Paulo
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
publisher.none.fl_str_mv Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
dc.source.none.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo; Vol. 38 No. 3 (1996); 171-175
Revista do Instituto de Medicina Tropical de São Paulo; Vol. 38 Núm. 3 (1996); 171-175
Revista do Instituto de Medicina Tropical de São Paulo; v. 38 n. 3 (1996); 171-175
1678-9946
0036-4665
reponame:Revista do Instituto de Medicina Tropical de São Paulo
instname:Instituto de Medicina Tropical (IMT)
instacron:IMT
instname_str Instituto de Medicina Tropical (IMT)
instacron_str IMT
institution IMT
reponame_str Revista do Instituto de Medicina Tropical de São Paulo
collection Revista do Instituto de Medicina Tropical de São Paulo
repository.name.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo - Instituto de Medicina Tropical (IMT)
repository.mail.fl_str_mv ||revimtsp@usp.br
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