Low bone mineral density among HIV-infected patients in Brazil

• Autor(a) principal: Chaba, Daniela Cardeal da Silva
• Data de Publicação: 2017
• Outros Autores: Soares, Lisméia R., Pereira, Rosa M. R., Rutherford, George W., Assone, Tatiane, Takayama, Liliam, Fonseca, Luiz A. M., Duarte, Alberto J. S., Casseb, Jorge
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
• Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/143758
• topic: HIV; Bone mineral; Osteoporosis; Risk factors

Decrease in bone mineral density (BMD) has been a complication among people living with HIV/AIDS. To investigate the prevalence of osteopenia/osteoporosis among HIV-infected people living in São Paulo city, we studied 108 HIV-infected patients (79 men and 29 women). We extracted data from patients’ medical records and BMD was measured by dual-energy X-ray absorptiometry (DXA). Median age of participants was 42 years (interquartile range [IQR] 36-48 years), and the median time since HIV diagnosis was 4.01 years (IQR 2-11 years). Patients had acquired HIV primarily by the sexual route (men who have sex with men 44%, heterosexual 49%). Median age, duration of HIV infection, duration of ART and CD4 nadir were similar for men and women. Plasma viral load was undetectable for 53 patients (49%). Median CD4 T cell count was 399 cells/µL (IQR 247 - 568). Twenty five patients (23%) had LBMD, and there was no statistically significant difference between men and women (