Acute petrified myocardium associated with meningococcal sepsis in childhood-onset systemic lupus erythematous: a fatal case

• Autor(a) principal: Santos, Ana Carolina Etrusco Zaroni
• Data de Publicação: 2019
• Outros Autores: Luglio, Michele, Delgado, Artur Figueiredo, Schuwartz, Constance Dell Santo Vieira, Marques, Heloísa Helena Sousa, Valões, Clarissa Carvalho de Miranda, Dominguez, Maria Andreina Cabrera, Carvalho, Werther Brunow de, Silva, Clovis Artur, Duarte-Neto, Amaro Nunes
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
• Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/162389
• topic: Myocardial calcification; Sepsis; Neisseria meningitides; Lupus; Intensive care

Acute petrified myocardium associated with septic shock, diagnosed by autopsy has rarely been described. A 15-year-old adolescent male was diagnosed with childhood-onset systemic lupus erythematosus. One year later, he was hospitalized with fever, myalgia, headache, arthritis, vomiting, dyspnea and was diagnosed with sepsis secondary to bronchopneumonia and meningitis. Blood culture identified Neisseria meningitidis serogroup Y. Despite antibiotics and intensive therapeutic measures, he died after 29 days of hospitalization. The autopsy revealed necrotic cardiomyocytes with dystrophic calcification and interstitial fibrosis.