Demographic and Clinical Profile of Cases of Hematological Neoplasms in Children and Adolescents
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | por eng |
Título da fonte: | Revista Brasileira de Cancerologia (Online) |
Texto Completo: | https://rbc.inca.gov.br/index.php/revista/article/view/2356 |
Resumo: | Introduction: Hematological cancers are important causes of death in childhood and adolescence. Objective: To design the demographic and clinical profile of cases of hematological cancer reported for children and adolescents in a referral hospital in the city of São Luís, Maranhão, Brazil. Method: A retrospective observational study with secondary data collected from medical records of bone marrow tumor cases in patients aged up to 19 years registered in a public referral hospital for cancer treatment from 2005 to 2015. Patient’s profile was collected in addition to follow-up data. The chi-square and Fisher’s exact test were used in the statistical analysis. The significance level was 5% (p<0.05). Results: Cases of death were higher in patients diagnosed with non-Hodgkin’s lymphoma. Most patients with lymphoid leukemia were males aged up to 5 years, and the frequency of death in patients with lymphoid leukemia was lower in confirmed cases of type B lymphoblastic precursor cell leukemia when compared to the other categories. Conclusion: The findings suggest that most patients aged up to 19 years diagnosed with lymphoid leukemia were males and aged up to 5 years old. |
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Demographic and Clinical Profile of Cases of Hematological Neoplasms in Children and AdolescentsPerfil Demográfico y Clínico de Casos de Neoplasias Hematológicas en Niños y AdolescentesPerfil Demográfico e Clínico de Casos de Neoplasias Hematológicas em Crianças e Adolescentesneoplasias hematológicasdemografiamortalidadecriançaadolescentehematologic neoplasmsdemographymortalitychildadolescentneoplasias hematológicasdemografíamortalidadniñoadolescenteIntroduction: Hematological cancers are important causes of death in childhood and adolescence. Objective: To design the demographic and clinical profile of cases of hematological cancer reported for children and adolescents in a referral hospital in the city of São Luís, Maranhão, Brazil. Method: A retrospective observational study with secondary data collected from medical records of bone marrow tumor cases in patients aged up to 19 years registered in a public referral hospital for cancer treatment from 2005 to 2015. Patient’s profile was collected in addition to follow-up data. The chi-square and Fisher’s exact test were used in the statistical analysis. The significance level was 5% (p<0.05). Results: Cases of death were higher in patients diagnosed with non-Hodgkin’s lymphoma. Most patients with lymphoid leukemia were males aged up to 5 years, and the frequency of death in patients with lymphoid leukemia was lower in confirmed cases of type B lymphoblastic precursor cell leukemia when compared to the other categories. Conclusion: The findings suggest that most patients aged up to 19 years diagnosed with lymphoid leukemia were males and aged up to 5 years old.Introducción: Las neoplasias hematológicas son causas importantes de muerte en la niñez y la adolescencia. Objetivo: Caracterizar el perfil demográfico y clínico de los casos notificados de neoplasias hematológicas en niños y adolescentes en un hospital de referencia de la ciudad de São Luís, Maranhão, Brasil. Método: estudio observacional retrospectivo con datos secundarios recolectados de registros médicos de casos de tumores de médula ósea en pacientes de hasta 19 años registrados en un hospital público de referencia para tratamiento de cáncer de 2005 a 2015. Se recolectaron datos de caracterización. Datos generales de pacientes y seguimiento -up datos. En el análisis estadístico se utilizaron las pruebas de chi-cuadrado y exacta de Fisher. El nivel de significancia adoptado fue del 5% (p<0,05). Resultados: Los casos de muerte fueron mayores en pacientes con diagnóstico de linfoma no Hodgkin. La mayoría de los pacientes con leucemia linfoide eran varones de hasta 5 años, y la frecuencia de muerte en pacientes con leucemia linfoide fue menor en los casos confirmados de leucemia de células precursoras linfoblásticas tipo B en comparación con las otras categorías. Conclusión: Los hallazgos sugieren que la mayoría de los pacientes de hasta 19 años diagnosticados con leucemia linfoide eran hombres y tenían hasta 5 años.Introdução: As neoplasias hematológicas são importantes causas de morte na infância e adolescência. Objetivo: Caracterizar o perfil demográfico e clínico de casos notificados de neoplasias hematológicas em crianças e adolescentes em um hospital de referência do município de São Luís, Maranhão, Brasil. Método: Estudo observacional retrospectivo com dados coletados de prontuários médicos de casos de neoplasias hematológicas em pacientes com idade até 19 anos registrados em um hospital público de referência para tratamento oncológico, no período de 2005 a 2015. Foram coletados dados de caracterização geral dos pacientes e dados do seguimento do tratamento. Os testes qui-quadrado e exato de Fisher foram utilizados na análise estatística. O nível de significância adotado foi de 5% (p<0,05). Resultados: Os casos de óbito foram mais elevados nos pacientes diagnosticados com linfoma não Hodgkin. A maioria dos pacientes com leucemia linfoide era do sexo masculino com idade até 5 anos, e a frequência de óbito nos pacientes com leucemia linfoide foi mais baixa nos casos confirmados de leucemia linfoblástica de células precursoras tipo B em comparação a outras categorias. Conclusão: Os achados sugerem que a maioria dos pacientes com até 19 anos diagnosticados com leucemia linfoide era do sexo masculino e com idade até 5 anos.INCA2022-06-22info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfapplication/pdftext/htmlhttps://rbc.inca.gov.br/index.php/revista/article/view/235610.32635/2176-9745.RBC.2022v68n2.2356Revista Brasileira de Cancerologia; Vol. 68 No. 2 (2022): Apr./May/June; e-242356Revista Brasileira de Cancerologia; Vol. 68 Núm. 2 (2022): abr./mayo/jun.; e-242356Revista Brasileira de Cancerologia; v. 68 n. 2 (2022): abr./maio./jun.; e-2423562176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporenghttps://rbc.inca.gov.br/index.php/revista/article/view/2356/1735https://rbc.inca.gov.br/index.php/revista/article/view/2356/2350https://rbc.inca.gov.br/index.php/revista/article/view/2356/1789Copyright (c) 2022 Revista Brasileira de Cancerologiahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessAraújo, Lucele Gonçalves Lima Rodrigues, Vandilson Pinheiro Silva, Melaine Mont’Alverne LawallAzevedo, Gabrielle Cristinne Alves Monteiro, Pablo de MatosFerreira, João Marcelo Saraiva Sousa, Huderson Macedo de 2022-10-27T16:47:54Zoai:rbc.inca.gov.br:article/2356Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2022-10-27T16:47:54Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false |
dc.title.none.fl_str_mv |
Demographic and Clinical Profile of Cases of Hematological Neoplasms in Children and Adolescents Perfil Demográfico y Clínico de Casos de Neoplasias Hematológicas en Niños y Adolescentes Perfil Demográfico e Clínico de Casos de Neoplasias Hematológicas em Crianças e Adolescentes |
title |
Demographic and Clinical Profile of Cases of Hematological Neoplasms in Children and Adolescents |
spellingShingle |
Demographic and Clinical Profile of Cases of Hematological Neoplasms in Children and Adolescents Araújo, Lucele Gonçalves Lima neoplasias hematológicas demografia mortalidade criança adolescente hematologic neoplasms demography mortality child adolescent neoplasias hematológicas demografía mortalidad niño adolescente |
title_short |
Demographic and Clinical Profile of Cases of Hematological Neoplasms in Children and Adolescents |
title_full |
Demographic and Clinical Profile of Cases of Hematological Neoplasms in Children and Adolescents |
title_fullStr |
Demographic and Clinical Profile of Cases of Hematological Neoplasms in Children and Adolescents |
title_full_unstemmed |
Demographic and Clinical Profile of Cases of Hematological Neoplasms in Children and Adolescents |
title_sort |
Demographic and Clinical Profile of Cases of Hematological Neoplasms in Children and Adolescents |
author |
Araújo, Lucele Gonçalves Lima |
author_facet |
Araújo, Lucele Gonçalves Lima Rodrigues, Vandilson Pinheiro Silva, Melaine Mont’Alverne Lawall Azevedo, Gabrielle Cristinne Alves Monteiro, Pablo de Matos Ferreira, João Marcelo Saraiva Sousa, Huderson Macedo de |
author_role |
author |
author2 |
Rodrigues, Vandilson Pinheiro Silva, Melaine Mont’Alverne Lawall Azevedo, Gabrielle Cristinne Alves Monteiro, Pablo de Matos Ferreira, João Marcelo Saraiva Sousa, Huderson Macedo de |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Araújo, Lucele Gonçalves Lima Rodrigues, Vandilson Pinheiro Silva, Melaine Mont’Alverne Lawall Azevedo, Gabrielle Cristinne Alves Monteiro, Pablo de Matos Ferreira, João Marcelo Saraiva Sousa, Huderson Macedo de |
dc.subject.por.fl_str_mv |
neoplasias hematológicas demografia mortalidade criança adolescente hematologic neoplasms demography mortality child adolescent neoplasias hematológicas demografía mortalidad niño adolescente |
topic |
neoplasias hematológicas demografia mortalidade criança adolescente hematologic neoplasms demography mortality child adolescent neoplasias hematológicas demografía mortalidad niño adolescente |
description |
Introduction: Hematological cancers are important causes of death in childhood and adolescence. Objective: To design the demographic and clinical profile of cases of hematological cancer reported for children and adolescents in a referral hospital in the city of São Luís, Maranhão, Brazil. Method: A retrospective observational study with secondary data collected from medical records of bone marrow tumor cases in patients aged up to 19 years registered in a public referral hospital for cancer treatment from 2005 to 2015. Patient’s profile was collected in addition to follow-up data. The chi-square and Fisher’s exact test were used in the statistical analysis. The significance level was 5% (p<0.05). Results: Cases of death were higher in patients diagnosed with non-Hodgkin’s lymphoma. Most patients with lymphoid leukemia were males aged up to 5 years, and the frequency of death in patients with lymphoid leukemia was lower in confirmed cases of type B lymphoblastic precursor cell leukemia when compared to the other categories. Conclusion: The findings suggest that most patients aged up to 19 years diagnosed with lymphoid leukemia were males and aged up to 5 years old. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-06-22 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Artigos, Avaliado pelos pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rbc.inca.gov.br/index.php/revista/article/view/2356 10.32635/2176-9745.RBC.2022v68n2.2356 |
url |
https://rbc.inca.gov.br/index.php/revista/article/view/2356 |
identifier_str_mv |
10.32635/2176-9745.RBC.2022v68n2.2356 |
dc.language.iso.fl_str_mv |
por eng |
language |
por eng |
dc.relation.none.fl_str_mv |
https://rbc.inca.gov.br/index.php/revista/article/view/2356/1735 https://rbc.inca.gov.br/index.php/revista/article/view/2356/2350 https://rbc.inca.gov.br/index.php/revista/article/view/2356/1789 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2022 Revista Brasileira de Cancerologia https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2022 Revista Brasileira de Cancerologia https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf text/html |
dc.publisher.none.fl_str_mv |
INCA |
publisher.none.fl_str_mv |
INCA |
dc.source.none.fl_str_mv |
Revista Brasileira de Cancerologia; Vol. 68 No. 2 (2022): Apr./May/June; e-242356 Revista Brasileira de Cancerologia; Vol. 68 Núm. 2 (2022): abr./mayo/jun.; e-242356 Revista Brasileira de Cancerologia; v. 68 n. 2 (2022): abr./maio./jun.; e-242356 2176-9745 reponame:Revista Brasileira de Cancerologia (Online) instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) instacron:INCA |
instname_str |
Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) |
instacron_str |
INCA |
institution |
INCA |
reponame_str |
Revista Brasileira de Cancerologia (Online) |
collection |
Revista Brasileira de Cancerologia (Online) |
repository.name.fl_str_mv |
Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) |
repository.mail.fl_str_mv |
rbc@inca.gov.br |
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1797042250146906112 |