Phospholipids Retard and Cholesterol and Its Derivatives Promote the Formation of Tumors Induced by Carcinogenic Hidrocarbons

Detalhes bibliográficos
Autor(a) principal: Altman, Reinout F. A.
Data de Publicação: 2023
Outros Autores: Pugachiov, Olga, Ballini-Kerr, Itália, Silva, Delcácio J. da, Pinto-Leon, Leonor L. S., Lopes , Carlos R. N., Freire, Ivan B.
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/4009
Resumo: It could be experimentally proved that phospholipids retard and cholesterol and its derivatives promote the formation of tumors induced by carcinogenic hydrocarbons. No sufficient stress can be laid upon the important phenomenon that two very common groups of lipids, i. e. natural components of whatever animal cell, positively influence the mechanism of carcinogenesis. The fact that phospholipids and cholesterol, besides proteins, constitute quantitatively speaking the most important components of cell membranes, led to the logic reasoning that cell surfaces actually do represent a key position in cancer etiology. A series of thusfar ununderstood phenomena can thus be explained satisfactorily.
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spelling Phospholipids Retard and Cholesterol and Its Derivatives Promote the Formation of Tumors Induced by Carcinogenic HidrocarbonsFosfolipídios Retardam e Colesterol e seus Derivados Aceleram a Formação de Tumores Induzidos por Hidrocarbonetos CancerígenosNeoplasias/induzido quimicamenteNeoplasias/etiologiaHidrocarbonetos/toxicidadeFosfolipídeosColesterolNeoplasms/chemically inducedNeoplasms/etiologyHydrocarbons/toxicityPhospholipidsCholesterolNeoplasias/inducido químicamenteNeoplasias/etiologíaHidrocarburos/toxicidadFosfolípidosColesterolIt could be experimentally proved that phospholipids retard and cholesterol and its derivatives promote the formation of tumors induced by carcinogenic hydrocarbons. No sufficient stress can be laid upon the important phenomenon that two very common groups of lipids, i. e. natural components of whatever animal cell, positively influence the mechanism of carcinogenesis. The fact that phospholipids and cholesterol, besides proteins, constitute quantitatively speaking the most important components of cell membranes, led to the logic reasoning that cell surfaces actually do represent a key position in cancer etiology. A series of thusfar ununderstood phenomena can thus be explained satisfactorily.Ficou experimentalmente comprovado que os fosfolipideos retardam e o colesterol e seus derivados aceleram a formação de tumores induzidos por hidrocarbonetos cancerígenos. Acentua-se a suma importância deste fenômeno, pois trata-se de dois grupos de lipídeos comuns, aliás componentes naturais de qualquer célula animal, capazes de influenciar, positivamente, o mecanismo da carcinogênese. O fato de que os fosfolipideos e o colesterol, ao lado das proteínas, constituem quantitativamente os componentes principais da membrana celular, conduziu ao raciocínio lógico que as membranas devem representar uma posição chave na etiologia do câncer.INCA2023-08-18info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/400910.32635/2176-9745.RBC.1968v24n38.4009Revista Brasileira de Cancerologia; Vol. 24 No. 38 (1968): Oct.; 73-81Revista Brasileira de Cancerologia; Vol. 24 Núm. 38 (1968): oct.; 73-81Revista Brasileira de Cancerologia; v. 24 n. 38 (1968): out.; 73-812176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/4009/2805Copyright (c) 2023 Revista Brasileira de Cancerologiahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessAltman, Reinout F. A.Pugachiov, OlgaBallini-Kerr, ItáliaSilva, Delcácio J. daPinto-Leon, Leonor L. S.Lopes , Carlos R. N.Freire, Ivan B.2023-08-18T19:50:53Zoai:rbc.inca.gov.br:article/4009Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2023-08-18T19:50:53Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Phospholipids Retard and Cholesterol and Its Derivatives Promote the Formation of Tumors Induced by Carcinogenic Hidrocarbons
Fosfolipídios Retardam e Colesterol e seus Derivados Aceleram a Formação de Tumores Induzidos por Hidrocarbonetos Cancerígenos
title Phospholipids Retard and Cholesterol and Its Derivatives Promote the Formation of Tumors Induced by Carcinogenic Hidrocarbons
spellingShingle Phospholipids Retard and Cholesterol and Its Derivatives Promote the Formation of Tumors Induced by Carcinogenic Hidrocarbons
Altman, Reinout F. A.
Neoplasias/induzido quimicamente
Neoplasias/etiologia
Hidrocarbonetos/toxicidade
Fosfolipídeos
Colesterol
Neoplasms/chemically induced
Neoplasms/etiology
Hydrocarbons/toxicity
Phospholipids
Cholesterol
Neoplasias/inducido químicamente
Neoplasias/etiología
Hidrocarburos/toxicidad
Fosfolípidos
Colesterol
title_short Phospholipids Retard and Cholesterol and Its Derivatives Promote the Formation of Tumors Induced by Carcinogenic Hidrocarbons
title_full Phospholipids Retard and Cholesterol and Its Derivatives Promote the Formation of Tumors Induced by Carcinogenic Hidrocarbons
title_fullStr Phospholipids Retard and Cholesterol and Its Derivatives Promote the Formation of Tumors Induced by Carcinogenic Hidrocarbons
title_full_unstemmed Phospholipids Retard and Cholesterol and Its Derivatives Promote the Formation of Tumors Induced by Carcinogenic Hidrocarbons
title_sort Phospholipids Retard and Cholesterol and Its Derivatives Promote the Formation of Tumors Induced by Carcinogenic Hidrocarbons
author Altman, Reinout F. A.
author_facet Altman, Reinout F. A.
Pugachiov, Olga
Ballini-Kerr, Itália
Silva, Delcácio J. da
Pinto-Leon, Leonor L. S.
Lopes , Carlos R. N.
Freire, Ivan B.
author_role author
author2 Pugachiov, Olga
Ballini-Kerr, Itália
Silva, Delcácio J. da
Pinto-Leon, Leonor L. S.
Lopes , Carlos R. N.
Freire, Ivan B.
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Altman, Reinout F. A.
Pugachiov, Olga
Ballini-Kerr, Itália
Silva, Delcácio J. da
Pinto-Leon, Leonor L. S.
Lopes , Carlos R. N.
Freire, Ivan B.
dc.subject.por.fl_str_mv Neoplasias/induzido quimicamente
Neoplasias/etiologia
Hidrocarbonetos/toxicidade
Fosfolipídeos
Colesterol
Neoplasms/chemically induced
Neoplasms/etiology
Hydrocarbons/toxicity
Phospholipids
Cholesterol
Neoplasias/inducido químicamente
Neoplasias/etiología
Hidrocarburos/toxicidad
Fosfolípidos
Colesterol
topic Neoplasias/induzido quimicamente
Neoplasias/etiologia
Hidrocarbonetos/toxicidade
Fosfolipídeos
Colesterol
Neoplasms/chemically induced
Neoplasms/etiology
Hydrocarbons/toxicity
Phospholipids
Cholesterol
Neoplasias/inducido químicamente
Neoplasias/etiología
Hidrocarburos/toxicidad
Fosfolípidos
Colesterol
description It could be experimentally proved that phospholipids retard and cholesterol and its derivatives promote the formation of tumors induced by carcinogenic hydrocarbons. No sufficient stress can be laid upon the important phenomenon that two very common groups of lipids, i. e. natural components of whatever animal cell, positively influence the mechanism of carcinogenesis. The fact that phospholipids and cholesterol, besides proteins, constitute quantitatively speaking the most important components of cell membranes, led to the logic reasoning that cell surfaces actually do represent a key position in cancer etiology. A series of thusfar ununderstood phenomena can thus be explained satisfactorily.
publishDate 2023
dc.date.none.fl_str_mv 2023-08-18
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Artigos, Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/4009
10.32635/2176-9745.RBC.1968v24n38.4009
url https://rbc.inca.gov.br/index.php/revista/article/view/4009
identifier_str_mv 10.32635/2176-9745.RBC.1968v24n38.4009
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/4009/2805
dc.rights.driver.fl_str_mv Copyright (c) 2023 Revista Brasileira de Cancerologia
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2023 Revista Brasileira de Cancerologia
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 24 No. 38 (1968): Oct.; 73-81
Revista Brasileira de Cancerologia; Vol. 24 Núm. 38 (1968): oct.; 73-81
Revista Brasileira de Cancerologia; v. 24 n. 38 (1968): out.; 73-81
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron:INCA
instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron_str INCA
institution INCA
reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
repository.mail.fl_str_mv rbc@inca.gov.br
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