A Review of Current Concepts In Cancer Chemotherapy

Detalhes bibliográficos
Autor(a) principal: Smaldone, Laurie F.
Data de Publicação: 2023
Outros Autores: Carter, Stehen K.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/3235
Resumo: Chemotherapy today is a modality predominantly used to treat metastatic or disseminated malignant neoplastic disease. Depending upon the primary site and stage (extent) of disease, chemotherapy can be geared to be curative or palliative in its intent. Chemotherapy can lead to prolonged disease-free survival in a percentage of patients with certain stages of eieven different malignancies (Table 1). For some of these, chemotherapy can eradicate all malignancy by itself in advanced stages when macroscopic metastatic disease is present. For the three pediatric solid tumors on the list, chemotherapy is used as an adjuvant to surgery and/or irradiation to eradicate microscopic metastatic disease after the local modalities have removed or abiated the primary local and residual disease.
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spelling A Review of Current Concepts In Cancer ChemotherapyTratamento FarmacológicoNeoplasias/terapiaNeoplasias/prevenção & controleAntineoplásicosDrug TherapyNeoplasms/therapyNeoplasms/prevention & controlAntineoplastic AgentsQuimioterapiaNeoplasias/terapiaNeoplasias/prevención & controlAntineoplásicosChemotherapy today is a modality predominantly used to treat metastatic or disseminated malignant neoplastic disease. Depending upon the primary site and stage (extent) of disease, chemotherapy can be geared to be curative or palliative in its intent. Chemotherapy can lead to prolonged disease-free survival in a percentage of patients with certain stages of eieven different malignancies (Table 1). For some of these, chemotherapy can eradicate all malignancy by itself in advanced stages when macroscopic metastatic disease is present. For the three pediatric solid tumors on the list, chemotherapy is used as an adjuvant to surgery and/or irradiation to eradicate microscopic metastatic disease after the local modalities have removed or abiated the primary local and residual disease.INCA2023-08-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionRevisão de literaturaapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/323510.32635/2176-9745.RBC.1986v32n1.3235Revista Brasileira de Cancerologia; Vol. 32 No. 1 (1986): Mar.; 49-62Revista Brasileira de Cancerologia; Vol. 32 Núm. 1 (1986): mar.; 49-62Revista Brasileira de Cancerologia; v. 32 n. 1 (1986): mar.; 49-622176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAenghttps://rbc.inca.gov.br/index.php/revista/article/view/3235/2092https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSmaldone, Laurie F.Carter, Stehen K.2023-08-07T18:56:00Zoai:rbc.inca.gov.br:article/3235Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2023-08-07T18:56Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv A Review of Current Concepts In Cancer Chemotherapy
title A Review of Current Concepts In Cancer Chemotherapy
spellingShingle A Review of Current Concepts In Cancer Chemotherapy
Smaldone, Laurie F.
Tratamento Farmacológico
Neoplasias/terapia
Neoplasias/prevenção & controle
Antineoplásicos
Drug Therapy
Neoplasms/therapy
Neoplasms/prevention & control
Antineoplastic Agents
Quimioterapia
Neoplasias/terapia
Neoplasias/prevención & control
Antineoplásicos
title_short A Review of Current Concepts In Cancer Chemotherapy
title_full A Review of Current Concepts In Cancer Chemotherapy
title_fullStr A Review of Current Concepts In Cancer Chemotherapy
title_full_unstemmed A Review of Current Concepts In Cancer Chemotherapy
title_sort A Review of Current Concepts In Cancer Chemotherapy
author Smaldone, Laurie F.
author_facet Smaldone, Laurie F.
Carter, Stehen K.
author_role author
author2 Carter, Stehen K.
author2_role author
dc.contributor.author.fl_str_mv Smaldone, Laurie F.
Carter, Stehen K.
dc.subject.por.fl_str_mv Tratamento Farmacológico
Neoplasias/terapia
Neoplasias/prevenção & controle
Antineoplásicos
Drug Therapy
Neoplasms/therapy
Neoplasms/prevention & control
Antineoplastic Agents
Quimioterapia
Neoplasias/terapia
Neoplasias/prevención & control
Antineoplásicos
topic Tratamento Farmacológico
Neoplasias/terapia
Neoplasias/prevenção & controle
Antineoplásicos
Drug Therapy
Neoplasms/therapy
Neoplasms/prevention & control
Antineoplastic Agents
Quimioterapia
Neoplasias/terapia
Neoplasias/prevención & control
Antineoplásicos
description Chemotherapy today is a modality predominantly used to treat metastatic or disseminated malignant neoplastic disease. Depending upon the primary site and stage (extent) of disease, chemotherapy can be geared to be curative or palliative in its intent. Chemotherapy can lead to prolonged disease-free survival in a percentage of patients with certain stages of eieven different malignancies (Table 1). For some of these, chemotherapy can eradicate all malignancy by itself in advanced stages when macroscopic metastatic disease is present. For the three pediatric solid tumors on the list, chemotherapy is used as an adjuvant to surgery and/or irradiation to eradicate microscopic metastatic disease after the local modalities have removed or abiated the primary local and residual disease.
publishDate 2023
dc.date.none.fl_str_mv 2023-08-07
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Revisão de literatura
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/3235
10.32635/2176-9745.RBC.1986v32n1.3235
url https://rbc.inca.gov.br/index.php/revista/article/view/3235
identifier_str_mv 10.32635/2176-9745.RBC.1986v32n1.3235
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/3235/2092
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 32 No. 1 (1986): Mar.; 49-62
Revista Brasileira de Cancerologia; Vol. 32 Núm. 1 (1986): mar.; 49-62
Revista Brasileira de Cancerologia; v. 32 n. 1 (1986): mar.; 49-62
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron:INCA
instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron_str INCA
institution INCA
reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
repository.mail.fl_str_mv rbc@inca.gov.br
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