Bisphosphonate-Induced Osteonecrosis of the Jaw: Case Report

Detalhes bibliográficos
Autor(a) principal: Caldas, Rogério Jardim
Data de Publicação: 2009
Outros Autores: Pontes, José Roberto de Menezes, Antunes, Héliton Spíndola
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/1645
Resumo: The jaws osteonecrosis induced by bisphosphonates is the first late complication of therapy with bisphosphonates described in scientific literature. This is defined as the development of necrotic bone in the oral cavity of a patient who is receiving treatment with bisphosphonates and did not receive radiotherapy in the head or neck region. Clinically, the lesions are characterized as ulceration of the oral mucosa, which is often very painful, and exposes the underlying bone. This paper reports a case of osteonecrosis induced by bisphosphonates of spontaneous surging, difficult to respond to conservative treatment, then achieving a cure with surgery.
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spelling Bisphosphonate-Induced Osteonecrosis of the Jaw: Case ReportOsteonecrose dos Maxilares Induzida por Bisfosfonatos: Relato de Caso ClínicoOsteonecroseMaxilaresBisfosfonatosOsteonecrosisJawBisphosphonatesThe jaws osteonecrosis induced by bisphosphonates is the first late complication of therapy with bisphosphonates described in scientific literature. This is defined as the development of necrotic bone in the oral cavity of a patient who is receiving treatment with bisphosphonates and did not receive radiotherapy in the head or neck region. Clinically, the lesions are characterized as ulceration of the oral mucosa, which is often very painful, and exposes the underlying bone. This paper reports a case of osteonecrosis induced by bisphosphonates of spontaneous surging, difficult to respond to conservative treatment, then achieving a cure with surgery.A osteonecrose dos maxilares induzida por bisfosfonatos é a primeira complicação tardia da terapia com bisfosfonatos descrita na literatura científica. Essa é definida como o desenvolvimento de osso necrótico na cavidade oral de um paciente que esteja recebendo tratamento com bisfosfonatos e não tenha recebido radioterapia em região de cabeça e pescoço. Clinicamente, as lesões se caracterizam como ulcerações da mucosa oral, frequentemente muito dolorosas, que expõem o osso subjacente. O objetivo deste trabalho é relatar um caso clínico de osteonecrose induzida por bisfosfonatos de surgimento espontâneo, com difícil resposta a tratamento conservador, alcançando a cura com cirurgia.INCA2009-06-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionRelato de Casoapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/164510.32635/2176-9745.RBC.2009v55n2.1645Revista Brasileira de Cancerologia; Vol. 55 No. 2 (2009): Apr/May/June; 151-155Revista Brasileira de Cancerologia; Vol. 55 Núm. 2 (2009): abr./mayo/jun.; 151-155Revista Brasileira de Cancerologia; v. 55 n. 2 (2009): abr./maio/jun.; 151-1552176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/1645/973Caldas, Rogério JardimPontes, José Roberto de MenezesAntunes, Héliton Spíndola info:eu-repo/semantics/openAccess2021-11-29T20:21:10Zoai:rbc.inca.gov.br:article/1645Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2021-11-29T20:21:10Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Bisphosphonate-Induced Osteonecrosis of the Jaw: Case Report
Osteonecrose dos Maxilares Induzida por Bisfosfonatos: Relato de Caso Clínico
title Bisphosphonate-Induced Osteonecrosis of the Jaw: Case Report
spellingShingle Bisphosphonate-Induced Osteonecrosis of the Jaw: Case Report
Caldas, Rogério Jardim
Osteonecrose
Maxilares
Bisfosfonatos
Osteonecrosis
Jaw
Bisphosphonates
title_short Bisphosphonate-Induced Osteonecrosis of the Jaw: Case Report
title_full Bisphosphonate-Induced Osteonecrosis of the Jaw: Case Report
title_fullStr Bisphosphonate-Induced Osteonecrosis of the Jaw: Case Report
title_full_unstemmed Bisphosphonate-Induced Osteonecrosis of the Jaw: Case Report
title_sort Bisphosphonate-Induced Osteonecrosis of the Jaw: Case Report
author Caldas, Rogério Jardim
author_facet Caldas, Rogério Jardim
Pontes, José Roberto de Menezes
Antunes, Héliton Spíndola
author_role author
author2 Pontes, José Roberto de Menezes
Antunes, Héliton Spíndola
author2_role author
author
dc.contributor.author.fl_str_mv Caldas, Rogério Jardim
Pontes, José Roberto de Menezes
Antunes, Héliton Spíndola
dc.subject.por.fl_str_mv Osteonecrose
Maxilares
Bisfosfonatos
Osteonecrosis
Jaw
Bisphosphonates
topic Osteonecrose
Maxilares
Bisfosfonatos
Osteonecrosis
Jaw
Bisphosphonates
description The jaws osteonecrosis induced by bisphosphonates is the first late complication of therapy with bisphosphonates described in scientific literature. This is defined as the development of necrotic bone in the oral cavity of a patient who is receiving treatment with bisphosphonates and did not receive radiotherapy in the head or neck region. Clinically, the lesions are characterized as ulceration of the oral mucosa, which is often very painful, and exposes the underlying bone. This paper reports a case of osteonecrosis induced by bisphosphonates of spontaneous surging, difficult to respond to conservative treatment, then achieving a cure with surgery.
publishDate 2009
dc.date.none.fl_str_mv 2009-06-30
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Relato de Caso
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/1645
10.32635/2176-9745.RBC.2009v55n2.1645
url https://rbc.inca.gov.br/index.php/revista/article/view/1645
identifier_str_mv 10.32635/2176-9745.RBC.2009v55n2.1645
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/1645/973
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 55 No. 2 (2009): Apr/May/June; 151-155
Revista Brasileira de Cancerologia; Vol. 55 Núm. 2 (2009): abr./mayo/jun.; 151-155
Revista Brasileira de Cancerologia; v. 55 n. 2 (2009): abr./maio/jun.; 151-155
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron:INCA
instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron_str INCA
institution INCA
reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
repository.mail.fl_str_mv rbc@inca.gov.br
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