Carcinosarcoma of the Uterus: Report of a Case with Invasion of the Urinary Bladder, Resembling Mullerianosis with Malignant Transformation
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Revista Brasileira de Cancerologia (Online) |
Texto Completo: | https://rbc.inca.gov.br/index.php/revista/article/view/638 |
Resumo: | Introduction: Uterine carcinosarcoma are infrequent neoplasms, corresponding to 3-9% of all gynecologic neoplasms only. They represent 48% of all sarcomas, with an incidence of 8.2 per 1 million women/year. The main clinical manifestations are postmenopausal vaginal bleeding and abdominal pain. Tumors are morphologically characterized by epithelial and stromal elements. They can eventually invade adjacent structures, including the urinary bladder. Case Report: We present a case of uterine carcinosarcoma with invasion of the urinary bladder resembling mullerianosis with malignant transformation. A 69 year-old female patient had macroscopic hematuria as the single complaint. During diagnostic investigations, after cystoscopy with anatomical and pathological exam was performed, the hypothesis of mullerianosis with benign transformation was suggested. The patient was thus submitted to surgical resection of this lesion. During the surgical procedure, we noticed the existence of a uterine tumor mass that was invading the urinary bladder, and after anatomical and pathological analysis, it was identified as a carcinosarcoma of the uterus with invasion of the urinary bladder. Conclusion: Unusual manifestation of diseases with great malignant potential, in addition to delay the process of diagnosis, directly interferes with the patient’s prognosis. |
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Carcinosarcoma of the Uterus: Report of a Case with Invasion of the Urinary Bladder, Resembling Mullerianosis with Malignant TransformationCarcinosarcoma Uterino: Reporte de un Caso de Invasión de la Vejiga, Mimetismo Mülleriano con Transformación MalignaCarcinossarcoma Uterino: Relato de um Caso com Invasão da Bexiga, Mimetizando Mullerianose com Transformação MalignaNeoplasias UterinasCarcinossarcomaÚteroBexiga UrináriaUterine NeoplasmsCarcinosarcomaUterusUrinary BladderNeoplasias UterinasCarcinosarcomaÚteroVejiga UrinariaIntroduction: Uterine carcinosarcoma are infrequent neoplasms, corresponding to 3-9% of all gynecologic neoplasms only. They represent 48% of all sarcomas, with an incidence of 8.2 per 1 million women/year. The main clinical manifestations are postmenopausal vaginal bleeding and abdominal pain. Tumors are morphologically characterized by epithelial and stromal elements. They can eventually invade adjacent structures, including the urinary bladder. Case Report: We present a case of uterine carcinosarcoma with invasion of the urinary bladder resembling mullerianosis with malignant transformation. A 69 year-old female patient had macroscopic hematuria as the single complaint. During diagnostic investigations, after cystoscopy with anatomical and pathological exam was performed, the hypothesis of mullerianosis with benign transformation was suggested. The patient was thus submitted to surgical resection of this lesion. During the surgical procedure, we noticed the existence of a uterine tumor mass that was invading the urinary bladder, and after anatomical and pathological analysis, it was identified as a carcinosarcoma of the uterus with invasion of the urinary bladder. Conclusion: Unusual manifestation of diseases with great malignant potential, in addition to delay the process of diagnosis, directly interferes with the patient’s prognosis. Introducción: Los carcinosarcomas uterinos son neoplasias poco frecuentes, correspondiente a solo 3-9% de todos los cánceres ginecológicos, lo que representa 48% do todos los sarcomas, e incidencia de 8,2 por 1 millón de mujeres/ año. Las principales manifestaciones clínicas son la sangría vaginal anormal en edad post-menopausa y dolor abdominal. Se caracterizan morfológicamente por elementos epiteliales y estromales. Pueden casualmente invadir estructuras adyacentes, incluso la vejiga urinaria. Informe de caso: Presentamos un caso de carcinosarcoma uterino con invasión de la vejiga, mimetismo mülleriano con transformación maligna. La paciente de 69 años presentaba hematuria macroscópica como queja única. Durante la investigación de diagnóstico, tras cistoscopia con examen anatómico e patológico, se planteó la posibilidad de mimetismo mülleriano con transformación benigna. La paciente fue luego remitida para la resección quirúrgica del tumor. Durante el procedimiento, se observó la existencia de un tumor uterino que invadía la vejiga urinaria, y después de un análisis anatómico y patológico demostró que se trataba de un carcinosarcoma uterino con invasión de la vejiga. Conclusión: Manifestaciones inusuales de enfermedades con alto potencial de malignidad, además de retrasar el proceso de diagnóstico, interfieren directamente en el pronóstico del paciente. Introdução: Os carcinossarcomas uterinos são neoplasias infrequentes, correspondendo a apenas 3-9% de todas as neoplasias ginecológicas, representam 48% de todos os sarcomas, e possuem incidência de 8,2 por 1 milhão mullheres/ano. As principais manifestações clínicas são o sangramento vaginal anormal em idade pós-menopausa e dor abdominal. Caracterizam-se morfologicamente por elementos epiteliais e estromais. Podem eventualmente invadir estruturas adjacentes, inclusive a bexiga urinária. Relato do caso: Apresentamos um caso de carcinossarcoma uterino com invasão de bexiga mimetizando mullerianose com transformação maligna. A paciente do sexo feminino de 69 anos apresentava hematuria macroscópica como queixa única. Durante a investigação diagnóstica, após cistoscopia com exame anatomopatológico, foi sugerida a hipótese de mullerianose com transformação benigna. A paciente foi então encaminhada para ressecção cirúrgica da neoplasia. Durante o procedimento cirúrgico, notou-se a existência de uma massa tumoral uterina que invadia a bexiga urinária, e, após análise anatomopatológica, mostrou tratar-se de um carcinossarcoma uterino com invasão vesical. Conclusão: Manifestações incomuns em doenças com grande potencial de malignidade, além de retardar o processo diagnóstico, interferem diretamente no prognóstico do paciente. INCA2012-03-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionRelato de Casoapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/63810.32635/2176-9745.RBC.2012v58n1.638Revista Brasileira de Cancerologia; Vol. 58 No. 1 (2012): Jan./Feb./Mar.; 79-83Revista Brasileira de Cancerologia; Vol. 58 Núm. 1 (2012): ene./feb./mar.; 79-83Revista Brasileira de Cancerologia; v. 58 n. 1 (2012): jan./fev./mar. ; 79-832176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/638/421Ogata, Daniel CuryBusato, Wilson S. F. Almeida, Gilberto LaurindoPereira Neto, Elisiário Moreira, Stefan Gerlach Braz Santos, João Vitor Quadra Vieira dos info:eu-repo/semantics/openAccess2021-11-29T20:15:05Zoai:rbc.inca.gov.br:article/638Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2021-11-29T20:15:05Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false |
dc.title.none.fl_str_mv |
Carcinosarcoma of the Uterus: Report of a Case with Invasion of the Urinary Bladder, Resembling Mullerianosis with Malignant Transformation Carcinosarcoma Uterino: Reporte de un Caso de Invasión de la Vejiga, Mimetismo Mülleriano con Transformación Maligna Carcinossarcoma Uterino: Relato de um Caso com Invasão da Bexiga, Mimetizando Mullerianose com Transformação Maligna |
title |
Carcinosarcoma of the Uterus: Report of a Case with Invasion of the Urinary Bladder, Resembling Mullerianosis with Malignant Transformation |
spellingShingle |
Carcinosarcoma of the Uterus: Report of a Case with Invasion of the Urinary Bladder, Resembling Mullerianosis with Malignant Transformation Ogata, Daniel Cury Neoplasias Uterinas Carcinossarcoma Útero Bexiga Urinária Uterine Neoplasms Carcinosarcoma Uterus Urinary Bladder Neoplasias Uterinas Carcinosarcoma Útero Vejiga Urinaria |
title_short |
Carcinosarcoma of the Uterus: Report of a Case with Invasion of the Urinary Bladder, Resembling Mullerianosis with Malignant Transformation |
title_full |
Carcinosarcoma of the Uterus: Report of a Case with Invasion of the Urinary Bladder, Resembling Mullerianosis with Malignant Transformation |
title_fullStr |
Carcinosarcoma of the Uterus: Report of a Case with Invasion of the Urinary Bladder, Resembling Mullerianosis with Malignant Transformation |
title_full_unstemmed |
Carcinosarcoma of the Uterus: Report of a Case with Invasion of the Urinary Bladder, Resembling Mullerianosis with Malignant Transformation |
title_sort |
Carcinosarcoma of the Uterus: Report of a Case with Invasion of the Urinary Bladder, Resembling Mullerianosis with Malignant Transformation |
author |
Ogata, Daniel Cury |
author_facet |
Ogata, Daniel Cury Busato, Wilson S. F. Almeida, Gilberto Laurindo Pereira Neto, Elisiário Moreira, Stefan Gerlach Braz Santos, João Vitor Quadra Vieira dos |
author_role |
author |
author2 |
Busato, Wilson S. F. Almeida, Gilberto Laurindo Pereira Neto, Elisiário Moreira, Stefan Gerlach Braz Santos, João Vitor Quadra Vieira dos |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Ogata, Daniel Cury Busato, Wilson S. F. Almeida, Gilberto Laurindo Pereira Neto, Elisiário Moreira, Stefan Gerlach Braz Santos, João Vitor Quadra Vieira dos |
dc.subject.por.fl_str_mv |
Neoplasias Uterinas Carcinossarcoma Útero Bexiga Urinária Uterine Neoplasms Carcinosarcoma Uterus Urinary Bladder Neoplasias Uterinas Carcinosarcoma Útero Vejiga Urinaria |
topic |
Neoplasias Uterinas Carcinossarcoma Útero Bexiga Urinária Uterine Neoplasms Carcinosarcoma Uterus Urinary Bladder Neoplasias Uterinas Carcinosarcoma Útero Vejiga Urinaria |
description |
Introduction: Uterine carcinosarcoma are infrequent neoplasms, corresponding to 3-9% of all gynecologic neoplasms only. They represent 48% of all sarcomas, with an incidence of 8.2 per 1 million women/year. The main clinical manifestations are postmenopausal vaginal bleeding and abdominal pain. Tumors are morphologically characterized by epithelial and stromal elements. They can eventually invade adjacent structures, including the urinary bladder. Case Report: We present a case of uterine carcinosarcoma with invasion of the urinary bladder resembling mullerianosis with malignant transformation. A 69 year-old female patient had macroscopic hematuria as the single complaint. During diagnostic investigations, after cystoscopy with anatomical and pathological exam was performed, the hypothesis of mullerianosis with benign transformation was suggested. The patient was thus submitted to surgical resection of this lesion. During the surgical procedure, we noticed the existence of a uterine tumor mass that was invading the urinary bladder, and after anatomical and pathological analysis, it was identified as a carcinosarcoma of the uterus with invasion of the urinary bladder. Conclusion: Unusual manifestation of diseases with great malignant potential, in addition to delay the process of diagnosis, directly interferes with the patient’s prognosis. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-03-30 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Relato de Caso |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rbc.inca.gov.br/index.php/revista/article/view/638 10.32635/2176-9745.RBC.2012v58n1.638 |
url |
https://rbc.inca.gov.br/index.php/revista/article/view/638 |
identifier_str_mv |
10.32635/2176-9745.RBC.2012v58n1.638 |
dc.language.iso.fl_str_mv |
por |
language |
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https://rbc.inca.gov.br/index.php/revista/article/view/638/421 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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INCA |
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INCA |
dc.source.none.fl_str_mv |
Revista Brasileira de Cancerologia; Vol. 58 No. 1 (2012): Jan./Feb./Mar.; 79-83 Revista Brasileira de Cancerologia; Vol. 58 Núm. 1 (2012): ene./feb./mar.; 79-83 Revista Brasileira de Cancerologia; v. 58 n. 1 (2012): jan./fev./mar. ; 79-83 2176-9745 reponame:Revista Brasileira de Cancerologia (Online) instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) instacron:INCA |
instname_str |
Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) |
instacron_str |
INCA |
institution |
INCA |
reponame_str |
Revista Brasileira de Cancerologia (Online) |
collection |
Revista Brasileira de Cancerologia (Online) |
repository.name.fl_str_mv |
Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) |
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rbc@inca.gov.br |
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1797042245210210304 |