Tumores Malignos do Intestino Delgado

Detalhes bibliográficos
Autor(a) principal: Ziliotto Júnior, Antonio
Data de Publicação: 2023
Outros Autores: Mendes, José Antonio Mansur, Kunzle, Johann Eugen, Delphini Júnior, Ovídio
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/3214
Resumo: Primary malignant tumours of the small intestine are uncommon and are often diagnosed at na advanced stage. Seventeen cases of malignant tumours of the small intestine were encountered over a 27-year period in the Serviço de Cirurgia from Ribeirão Preto. The ileum was the most common location, with a decreasing frequency proximally. Synchronous tumours were found in 35.29% of the patients. Presenting signs and symptoms were vague and related mainly to abdominal pain (94.12%), nausea and vomiting (52.94%), weight loss (52.94%), and anorexia (35.29%). An abdominal tumour was evident in 35.29910 of patients. Three patients presented with perforation of the tumour, one of them af ter radiotherapy. Barium contrast examination was the primary complementary diagnostic modality. The treatment was wide resection of bowel and mesentery, whenever possible, for jejunal and ileal tumours, together with resection of other involved organs. In one case only biopsy could be perforrned. Lymphoma was the most common malignancy, followed by leiomyosarcoma and adenocarcinoma. The operative mortality was 23.53% (4 patients), 3 from sepsis (two opera ted on with peritonitis) and one from anesthetic problem. Adjuvant radiotherapy and/or chemotherapy was used in the patients who survived surgery except in one. AlI leiomyosarcoma recurred and the patients were opera ted on again with a new resection. Four patients are alive from 2 to 15 years af ter surgery The 5-year survival rate for the lymphomas is 25% (38% if the operative deaths are excluded), and for the adenocarcinoma is 100% (only 2 cases). Whereas the symptoms are vague, the diagnostic of small bowel tumour must be cogitated if the prognosis is to be improved.
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spelling Tumores Malignos do Intestino DelgadoTumores do DelgadoCâncer do Intestino DelgadoIntestinal TumoursCancer of the Small BowelPrimary malignant tumours of the small intestine are uncommon and are often diagnosed at na advanced stage. Seventeen cases of malignant tumours of the small intestine were encountered over a 27-year period in the Serviço de Cirurgia from Ribeirão Preto. The ileum was the most common location, with a decreasing frequency proximally. Synchronous tumours were found in 35.29% of the patients. Presenting signs and symptoms were vague and related mainly to abdominal pain (94.12%), nausea and vomiting (52.94%), weight loss (52.94%), and anorexia (35.29%). An abdominal tumour was evident in 35.29910 of patients. Three patients presented with perforation of the tumour, one of them af ter radiotherapy. Barium contrast examination was the primary complementary diagnostic modality. The treatment was wide resection of bowel and mesentery, whenever possible, for jejunal and ileal tumours, together with resection of other involved organs. In one case only biopsy could be perforrned. Lymphoma was the most common malignancy, followed by leiomyosarcoma and adenocarcinoma. The operative mortality was 23.53% (4 patients), 3 from sepsis (two opera ted on with peritonitis) and one from anesthetic problem. Adjuvant radiotherapy and/or chemotherapy was used in the patients who survived surgery except in one. AlI leiomyosarcoma recurred and the patients were opera ted on again with a new resection. Four patients are alive from 2 to 15 years af ter surgery The 5-year survival rate for the lymphomas is 25% (38% if the operative deaths are excluded), and for the adenocarcinoma is 100% (only 2 cases). Whereas the symptoms are vague, the diagnostic of small bowel tumour must be cogitated if the prognosis is to be improved.Os tumores malignos primários do intestino delgado são raros e freqüentemente diagnosticados em estádios avançados. Num período de 27 anos (1960-1987) foram atendidos no Serviço de Cirurgia de Ribeirão Preto, 17 pacientes com neoplasia maligna de delgado. A maior parte das lesões se assestavam no ileo, com freqüência decrescente a montante. Havia tumores sincrônicos em 35,29% dos casos. Os sinais e sintomas clínicos mais freqüentes foram: dor abdominal (94,12%), náuseas e vômitos (52,94%), perda de peso (52,94%) e anorexia (35,29%). Por ocasião do primeiro atendimento, 3 pacientes tinham peritonite por perfuração do tumor, uma delas subseqüente à radioterapia. Dos exames complementares, o de maior valor foi o estudo radiológico contrastado do delgado. O tratamento consistiu na ressecção do segmento comprometido e do mesentério, incluindo outros órgãos eventualmente envolvidos. Em um caso, apenas a biópsia pôde ser realizada. O tipo histológico mais freqüente foi o linfoma, seguido pelo leiomiossarcoma eadenocarcinoma. Tivemos a lamentar 4 óbitos operatórios (23,53%), 3 por choque séptico (2 operados na vigência de peritonite e 1 por deiscência de anastomose) e 1 por acidente anestésico. Foi empregada a quimio e/ou radioterapia adjuvante em todos os pacientes que sobreviveram o pós-operatóno, à exceção de um paciente que se negou a recebê-los. Todos os 3 pacientes com leiomiossarcoma apresentaram recidiva e foram reoperados. Quatro pacientes estavam vivos por ocasião do último seguimento, com sobrevida entre 2 e 15 anos. A sobrevida de 5 anos foi de 25% para os linfomas (38% quando excluídos os óbitos operatórios) e de 100% para os adenocarcinomas, embora se trate de apenas 2 casos. Desde que os sinais e sintomas nos tumores de delgado são vagos e mal definidos, é necessário que esse diagnóstico seja cogitado para que o diagnóstico mais precoce seja estabelecido e conseqüentemente se tenha um melhor prognóstico.INCA2023-08-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/321410.32635/2176-9745.RBC.1987v33n3.3214Revista Brasileira de Cancerologia; Vol. 33 No. 3 (1987): Sept.; 235-240Revista Brasileira de Cancerologia; Vol. 33 Núm. 3 (1987): sept.; 235-240Revista Brasileira de Cancerologia; v. 33 n. 3 (1987): set.; 235-2402176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/3214/2073https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessZiliotto Júnior, AntonioMendes, José Antonio MansurKunzle, Johann EugenDelphini Júnior, Ovídio2023-08-03T20:44:22Zoai:rbc.inca.gov.br:article/3214Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2023-08-03T20:44:22Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Tumores Malignos do Intestino Delgado
title Tumores Malignos do Intestino Delgado
spellingShingle Tumores Malignos do Intestino Delgado
Ziliotto Júnior, Antonio
Tumores do Delgado
Câncer do Intestino Delgado
Intestinal Tumours
Cancer of the Small Bowel
title_short Tumores Malignos do Intestino Delgado
title_full Tumores Malignos do Intestino Delgado
title_fullStr Tumores Malignos do Intestino Delgado
title_full_unstemmed Tumores Malignos do Intestino Delgado
title_sort Tumores Malignos do Intestino Delgado
author Ziliotto Júnior, Antonio
author_facet Ziliotto Júnior, Antonio
Mendes, José Antonio Mansur
Kunzle, Johann Eugen
Delphini Júnior, Ovídio
author_role author
author2 Mendes, José Antonio Mansur
Kunzle, Johann Eugen
Delphini Júnior, Ovídio
author2_role author
author
author
dc.contributor.author.fl_str_mv Ziliotto Júnior, Antonio
Mendes, José Antonio Mansur
Kunzle, Johann Eugen
Delphini Júnior, Ovídio
dc.subject.por.fl_str_mv Tumores do Delgado
Câncer do Intestino Delgado
Intestinal Tumours
Cancer of the Small Bowel
topic Tumores do Delgado
Câncer do Intestino Delgado
Intestinal Tumours
Cancer of the Small Bowel
description Primary malignant tumours of the small intestine are uncommon and are often diagnosed at na advanced stage. Seventeen cases of malignant tumours of the small intestine were encountered over a 27-year period in the Serviço de Cirurgia from Ribeirão Preto. The ileum was the most common location, with a decreasing frequency proximally. Synchronous tumours were found in 35.29% of the patients. Presenting signs and symptoms were vague and related mainly to abdominal pain (94.12%), nausea and vomiting (52.94%), weight loss (52.94%), and anorexia (35.29%). An abdominal tumour was evident in 35.29910 of patients. Three patients presented with perforation of the tumour, one of them af ter radiotherapy. Barium contrast examination was the primary complementary diagnostic modality. The treatment was wide resection of bowel and mesentery, whenever possible, for jejunal and ileal tumours, together with resection of other involved organs. In one case only biopsy could be perforrned. Lymphoma was the most common malignancy, followed by leiomyosarcoma and adenocarcinoma. The operative mortality was 23.53% (4 patients), 3 from sepsis (two opera ted on with peritonitis) and one from anesthetic problem. Adjuvant radiotherapy and/or chemotherapy was used in the patients who survived surgery except in one. AlI leiomyosarcoma recurred and the patients were opera ted on again with a new resection. Four patients are alive from 2 to 15 years af ter surgery The 5-year survival rate for the lymphomas is 25% (38% if the operative deaths are excluded), and for the adenocarcinoma is 100% (only 2 cases). Whereas the symptoms are vague, the diagnostic of small bowel tumour must be cogitated if the prognosis is to be improved.
publishDate 2023
dc.date.none.fl_str_mv 2023-08-03
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10.32635/2176-9745.RBC.1987v33n3.3214
url https://rbc.inca.gov.br/index.php/revista/article/view/3214
identifier_str_mv 10.32635/2176-9745.RBC.1987v33n3.3214
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dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 33 No. 3 (1987): Sept.; 235-240
Revista Brasileira de Cancerologia; Vol. 33 Núm. 3 (1987): sept.; 235-240
Revista Brasileira de Cancerologia; v. 33 n. 3 (1987): set.; 235-240
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
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reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
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