Nutritional Profile of Children with Brain Tumor with Diencephalic Syndrome or Russell Syndrome receiving Enteral Diet

Detalhes bibliográficos
Autor(a) principal: Garófolo, Adriana
Data de Publicação: 2018
Outros Autores: Silva, Nasjla Saba, Cavalheiro, Sérgio
Tipo de documento: Artigo
Idioma: por
eng
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/36
Resumo: Introduction: Diencephalic syndrome is a rare disorder of infancy characterized by profound emaciation with failure to thrive. The majority of cases of the syndrome are due to low grade gliomas of the anterior hypothalamus or optic nerve. Objective: To report the nutritional status and efficacy of nutritional support in patients with brain tumors that developed the Russell’s Syndrome. Method: Seven patients were retrospectively evaluated by means of z-score of the weight for age (W/A), weight for height (W/H) and Height for age (H/A) nutritional status index, for protein-energy malnutrition diagnosis. They were evaluated by means of triceps skinfold thickness (TSFT), arm circumferences (AC) and muscle arm circumferences (MAC) and received enteral nutrition, by nasoenteral tube or gastrostomy at cancer diagnostic. Results: The ages ranged from 2 months to 13 years, five children were males. Mean of the nutritional support was 7 months (1.1-18.5 months) after diagnostic, without statistical differences in z-scores evolution, but there are increase in averages of the W/A (-4,42 to -3,50) and W/H (-3,06 to -1,99), and body composition indicators (TSFT): 2.85 to 4.88, AC: 9.81 to 11.84 and MAC: 8.91 to 10.31). There was decreased in average of H/A, evidencing the growth arrest of these children. Conclusion: Enteral feeding has been shown to guarantee nutritional supply and to partially recover nutritional indicators of acute malnutrition; especially body fat, rather than lean mass. However, the growth deficit was not corrected, being aggravated in most cases. Nutritional support should be implanted during oncological treatment, ensuring its maintenance. 
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spelling Nutritional Profile of Children with Brain Tumor with Diencephalic Syndrome or Russell Syndrome receiving Enteral DietPerfil Nutricional de Niños Portadores de Tumores Cerebrales con Síndrome diencefálico o Síndrome de Russell recibiendo dieta EnteralPerfil Nutricional de Crianças Portadoras de Tumores Cerebrais com Síndrome Diencefálica ou Síndrome de Russell recebendo Dieta EnteralSíndrome de Silver-RussellNeoplasias EncefálicasNutrição EnteralTerapia NutricionalCriançaSilver-Russell SyndromeBrain NeoplasmsEnteral NutritionNutrition TherapyChildSíndrome de Silver-RussellNeoplasias EncefálicasNutrición EnteralTerapia NutricionalNiñoIntroduction: Diencephalic syndrome is a rare disorder of infancy characterized by profound emaciation with failure to thrive. The majority of cases of the syndrome are due to low grade gliomas of the anterior hypothalamus or optic nerve. Objective: To report the nutritional status and efficacy of nutritional support in patients with brain tumors that developed the Russell’s Syndrome. Method: Seven patients were retrospectively evaluated by means of z-score of the weight for age (W/A), weight for height (W/H) and Height for age (H/A) nutritional status index, for protein-energy malnutrition diagnosis. They were evaluated by means of triceps skinfold thickness (TSFT), arm circumferences (AC) and muscle arm circumferences (MAC) and received enteral nutrition, by nasoenteral tube or gastrostomy at cancer diagnostic. Results: The ages ranged from 2 months to 13 years, five children were males. Mean of the nutritional support was 7 months (1.1-18.5 months) after diagnostic, without statistical differences in z-scores evolution, but there are increase in averages of the W/A (-4,42 to -3,50) and W/H (-3,06 to -1,99), and body composition indicators (TSFT): 2.85 to 4.88, AC: 9.81 to 11.84 and MAC: 8.91 to 10.31). There was decreased in average of H/A, evidencing the growth arrest of these children. Conclusion: Enteral feeding has been shown to guarantee nutritional supply and to partially recover nutritional indicators of acute malnutrition; especially body fat, rather than lean mass. However, the growth deficit was not corrected, being aggravated in most cases. Nutritional support should be implanted during oncological treatment, ensuring its maintenance. Introducción: El síndrome diencefalica es una enfermedad pediátrica rara, derivada de tumores de la región hipotalámica, caracterizada por failure to thrive. Objetivo: Describir condiciones nutricionales y terapia nutricional de pacientes con tumor es cerebrales com síndrome diencefalica y nutrición enteral. Método: Siete pacientes fueron acompañados de julio/1999 as abril/2002 y analizados retrospectivamente, usando el score-Z de peso para edad (P/I), peso para estatura (P/E) y estatura para edad (E/I) para el diagnóstico de la desnutrición. Todos fueron evaluados por composición corporal (pliegue cutáneo triciptal y circunferencias del brazo y muscular del brazo). Los pacientes recibieron nutrición enteral por sonda o gastrostomía, luego del diagnóstico de cancer. Resultados: La edad varía de 2 meses a 13 años, cinco del sexo masculino. La duración media de la nutrición enteral fue de 7 meses (1,1-18,5) después del diagnóstico. No hubo diferencia estadística en la evolución nutricional, a pesar del aumento en P/I (-4,42 a -3,50) y P/E (-3,06 a -1,99), así como en la composición corporal (PCT: 2, 85 a 4,88, CB: 9,81 a 11,84 y CMB: 8,91 para 10.31). Hubo una reducción de E/I, caracterizando el retraso en el crecimiento. Conclusión: La nutrición enteral demostró garantizar la oferta nutricional.e la recuperación parcial de la desnutrición aguda, principalmente grasa corporal, más que masa magra, sin respuesta al déficit en el crecimiento, que se agravó en casi todos los casos. La terapia nutricional debe ser implantada durante el tratamiento oncológico, asegurando su continuidad.Introdução: A síndrome diencefálica é uma doença pediátrica rara, decorrente de tumores hipotalâmicos, caracterizada por failure to thrive. Objetivo: Descrever o estado nutricional e a terapia nutricional por meio de sonda nasoenteral de pacientes com tumores cerebrais com a síndrome diencefálica. Método: Sete pacientes foram acompanhados de julho/1999 a abril/2002 e analisados retrospectivamente, usando os escores-z de peso para idade (P/I), peso para estatura (P/E) e estatura para idade (E/I) no diagnóstico da desnutrição. Todos foram avaliados por meio de composição corporal: prega cutânea triciptal (PCT) e circunferências do braço e muscular do braço (CB e CMB) e receberam alimentação por sonda nasoenteral ou gastrostomia após o diagnóstico da neoplasia. Resultados: A idade variou de 2 meses a 13 anos, cinco do sexo masculino. A duração média da nutrição enteral foi de 7 meses (1,1-18,5) após o diagnóstico, sem diferença estatística significante na evolução dos escores-z, apesar do aumento nas médias de P/I (-4,42 para -3,50) e P/E (-3,06 para -1,99), e dos indicadores de composição corporal (PCT: 2,85 para 4,88; CB: 9,81 para 11,84 e CMB: 8,91 para 10,31). Houve redução na média da E/I, caracterizando o atraso no crescimento dessas crianças. Conclusão: A nutrição enteral demonstrou garantir a oferta nutricional e recuperar em parte os indicadores nutricionais de desnutrição aguda; principalmente a gordura corporal, mais do que massa magra. Entretanto, manteve-se o déficit de crescimento, agravado na maioria dos casos. A terapia nutricional deve ser implantada durante o tratamento oncológico, assegurando sua continuidade.INCA2018-09-28info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/3610.32635/2176-9745.RBC.2018v64n3.36Revista Brasileira de Cancerologia; Vol. 64 No. 3 (2018): July/Aug./Sept.; 357-363Revista Brasileira de Cancerologia; Vol. 64 Núm. 3 (2018): jul./agosto/sept.; 357-363Revista Brasileira de Cancerologia; v. 64 n. 3 (2018): jul./ago./set.; 357-3632176-974510.32635/2176-9745.RBC.2018v64n3reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporenghttps://rbc.inca.gov.br/index.php/revista/article/view/36/12https://rbc.inca.gov.br/index.php/revista/article/view/36/195Garófolo, AdrianaSilva, Nasjla SabaCavalheiro, Sérgioinfo:eu-repo/semantics/openAccess2021-11-29T20:06:09Zoai:rbc.inca.gov.br:article/36Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2021-11-29T20:06:09Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Nutritional Profile of Children with Brain Tumor with Diencephalic Syndrome or Russell Syndrome receiving Enteral Diet
Perfil Nutricional de Niños Portadores de Tumores Cerebrales con Síndrome diencefálico o Síndrome de Russell recibiendo dieta Enteral
Perfil Nutricional de Crianças Portadoras de Tumores Cerebrais com Síndrome Diencefálica ou Síndrome de Russell recebendo Dieta Enteral
title Nutritional Profile of Children with Brain Tumor with Diencephalic Syndrome or Russell Syndrome receiving Enteral Diet
spellingShingle Nutritional Profile of Children with Brain Tumor with Diencephalic Syndrome or Russell Syndrome receiving Enteral Diet
Garófolo, Adriana
Síndrome de Silver-Russell
Neoplasias Encefálicas
Nutrição Enteral
Terapia Nutricional
Criança
Silver-Russell Syndrome
Brain Neoplasms
Enteral Nutrition
Nutrition Therapy
Child
Síndrome de Silver-Russell
Neoplasias Encefálicas
Nutrición Enteral
Terapia Nutricional
Niño
title_short Nutritional Profile of Children with Brain Tumor with Diencephalic Syndrome or Russell Syndrome receiving Enteral Diet
title_full Nutritional Profile of Children with Brain Tumor with Diencephalic Syndrome or Russell Syndrome receiving Enteral Diet
title_fullStr Nutritional Profile of Children with Brain Tumor with Diencephalic Syndrome or Russell Syndrome receiving Enteral Diet
title_full_unstemmed Nutritional Profile of Children with Brain Tumor with Diencephalic Syndrome or Russell Syndrome receiving Enteral Diet
title_sort Nutritional Profile of Children with Brain Tumor with Diencephalic Syndrome or Russell Syndrome receiving Enteral Diet
author Garófolo, Adriana
author_facet Garófolo, Adriana
Silva, Nasjla Saba
Cavalheiro, Sérgio
author_role author
author2 Silva, Nasjla Saba
Cavalheiro, Sérgio
author2_role author
author
dc.contributor.author.fl_str_mv Garófolo, Adriana
Silva, Nasjla Saba
Cavalheiro, Sérgio
dc.subject.por.fl_str_mv Síndrome de Silver-Russell
Neoplasias Encefálicas
Nutrição Enteral
Terapia Nutricional
Criança
Silver-Russell Syndrome
Brain Neoplasms
Enteral Nutrition
Nutrition Therapy
Child
Síndrome de Silver-Russell
Neoplasias Encefálicas
Nutrición Enteral
Terapia Nutricional
Niño
topic Síndrome de Silver-Russell
Neoplasias Encefálicas
Nutrição Enteral
Terapia Nutricional
Criança
Silver-Russell Syndrome
Brain Neoplasms
Enteral Nutrition
Nutrition Therapy
Child
Síndrome de Silver-Russell
Neoplasias Encefálicas
Nutrición Enteral
Terapia Nutricional
Niño
description Introduction: Diencephalic syndrome is a rare disorder of infancy characterized by profound emaciation with failure to thrive. The majority of cases of the syndrome are due to low grade gliomas of the anterior hypothalamus or optic nerve. Objective: To report the nutritional status and efficacy of nutritional support in patients with brain tumors that developed the Russell’s Syndrome. Method: Seven patients were retrospectively evaluated by means of z-score of the weight for age (W/A), weight for height (W/H) and Height for age (H/A) nutritional status index, for protein-energy malnutrition diagnosis. They were evaluated by means of triceps skinfold thickness (TSFT), arm circumferences (AC) and muscle arm circumferences (MAC) and received enteral nutrition, by nasoenteral tube or gastrostomy at cancer diagnostic. Results: The ages ranged from 2 months to 13 years, five children were males. Mean of the nutritional support was 7 months (1.1-18.5 months) after diagnostic, without statistical differences in z-scores evolution, but there are increase in averages of the W/A (-4,42 to -3,50) and W/H (-3,06 to -1,99), and body composition indicators (TSFT): 2.85 to 4.88, AC: 9.81 to 11.84 and MAC: 8.91 to 10.31). There was decreased in average of H/A, evidencing the growth arrest of these children. Conclusion: Enteral feeding has been shown to guarantee nutritional supply and to partially recover nutritional indicators of acute malnutrition; especially body fat, rather than lean mass. However, the growth deficit was not corrected, being aggravated in most cases. Nutritional support should be implanted during oncological treatment, ensuring its maintenance. 
publishDate 2018
dc.date.none.fl_str_mv 2018-09-28
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Artigos, Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/36
10.32635/2176-9745.RBC.2018v64n3.36
url https://rbc.inca.gov.br/index.php/revista/article/view/36
identifier_str_mv 10.32635/2176-9745.RBC.2018v64n3.36
dc.language.iso.fl_str_mv por
eng
language por
eng
dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/36/12
https://rbc.inca.gov.br/index.php/revista/article/view/36/195
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 64 No. 3 (2018): July/Aug./Sept.; 357-363
Revista Brasileira de Cancerologia; Vol. 64 Núm. 3 (2018): jul./agosto/sept.; 357-363
Revista Brasileira de Cancerologia; v. 64 n. 3 (2018): jul./ago./set.; 357-363
2176-9745
10.32635/2176-9745.RBC.2018v64n3
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron:INCA
instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron_str INCA
institution INCA
reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
repository.mail.fl_str_mv rbc@inca.gov.br
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