Doença de Hodgkin: Resultados de Tratamentos de 61 Pacientes

Detalhes bibliográficos
Autor(a) principal: Faria, Sérgio Luis
Data de Publicação: 2023
Outros Autores: Murtinho, Regina Maciel
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/3241
Resumo: Hodgkin's disease (HD) represents 1/3 of malignant lymphomas. It's one of the most curable cancers today, after appropriate use of radio and chemotherapy. However, these treatments may cause important complications like sterility or new cancer. Thus, it is not easy to obtain. good control of the disease with little complications. This report shows the results of 61 adult patients with HD treated at Centro de Oncologia Campinas between january/1978 and july/1985. Sixteen patients were stage I, 21 stage II, 20 stage III and 4 stage IV. Overall survival was of 92% and disease free survival was of 75% in five years, with mean follow up time of 36 months. Some difficulties were found during staging procedures due to our still limited system of social medicine. Of 32/61 (52%) patients where gonadal dysfunction was investigated, 21 (66%) did not show abnormalities. Only one patient had a secondary cancer (of the cervix), probably not related to the treatments, but further follow up is necessary, in order to obtain a better evaluation.
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spelling Doença de Hodgkin: Resultados de Tratamentos de 61 PacientesDoença de HodgkinRadioterapiaQuimioterapiaComplicaçõesHodgkin's DiseaseRadiotherapyChemotherapyComplicationsHodgkin's disease (HD) represents 1/3 of malignant lymphomas. It's one of the most curable cancers today, after appropriate use of radio and chemotherapy. However, these treatments may cause important complications like sterility or new cancer. Thus, it is not easy to obtain. good control of the disease with little complications. This report shows the results of 61 adult patients with HD treated at Centro de Oncologia Campinas between january/1978 and july/1985. Sixteen patients were stage I, 21 stage II, 20 stage III and 4 stage IV. Overall survival was of 92% and disease free survival was of 75% in five years, with mean follow up time of 36 months. Some difficulties were found during staging procedures due to our still limited system of social medicine. Of 32/61 (52%) patients where gonadal dysfunction was investigated, 21 (66%) did not show abnormalities. Only one patient had a secondary cancer (of the cervix), probably not related to the treatments, but further follow up is necessary, in order to obtain a better evaluation.A Doença de Hodgkin representa um terço dos linfomas malignos. É um dos cânceres mais curáveis hoje, com a utilização da radioterapia e quimioterapia adequadas Estes tratamentos, apesar de oferecerem alto índice de cura, podem causar complicações importantes como esterilidade ou nova neoplasia. É responsabilidade de quem trata pacientes com Linfoma de Hodgkin obter ótimo índice de controle tumoral com baixo índice de complicações, e este objetivo n50 é fácil. No presente trabalho analisamos 61 casos de pacientes adultos com Doença de Hodgkin, tratados no Centro de Oncologia Campinas, de janeiro de 1978 a julho de 1985. Em relação ao estadiamento 16 eram estádio 1, 21 eram 11, 20 eram III e 4 eram IV. A sobrevida global foi de 9210 9 e a sobrevida livre de doença foi de 75%, em cinco anos O tempo médio de seguimento foi de 36 meses. Na fase 9 de avaliação de extensão de doença, houve algumas dificuldades ligadas à nossa deficitária medicina social ainda em desenvolvimento, mas que não repercutiu no controle da neoplasia. Em dois terços dos casos, que puderam ter uma avaliação da função gonadal, não houve alteração menstrual ou azoospermia a longo prazo devidos aos tratamentos. Houve apenas um caso de segunda neoplasia, provavelmente não relacionada com os tratamentos previamente recebidos pela paciente, mas como estas complicações tumorais aparecem tardiamente é necessário maior seguimento.INCA2023-08-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/324110.32635/2176-9745.RBC.1986v32n2.3241Revista Brasileira de Cancerologia; Vol. 32 No. 2 (1986): June; 95-100Revista Brasileira de Cancerologia; Vol. 32 Núm. 2 (1986): jun.; 95-100Revista Brasileira de Cancerologia; v. 32 n. 2 (1986): jun.; 95-1002176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/3241/2097https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessFaria, Sérgio LuisMurtinho, Regina Maciel2023-08-07T18:18:13Zoai:rbc.inca.gov.br:article/3241Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2023-08-07T18:18:13Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Doença de Hodgkin: Resultados de Tratamentos de 61 Pacientes
title Doença de Hodgkin: Resultados de Tratamentos de 61 Pacientes
spellingShingle Doença de Hodgkin: Resultados de Tratamentos de 61 Pacientes
Faria, Sérgio Luis
Doença de Hodgkin
Radioterapia
Quimioterapia
Complicações
Hodgkin's Disease
Radiotherapy
Chemotherapy
Complications
title_short Doença de Hodgkin: Resultados de Tratamentos de 61 Pacientes
title_full Doença de Hodgkin: Resultados de Tratamentos de 61 Pacientes
title_fullStr Doença de Hodgkin: Resultados de Tratamentos de 61 Pacientes
title_full_unstemmed Doença de Hodgkin: Resultados de Tratamentos de 61 Pacientes
title_sort Doença de Hodgkin: Resultados de Tratamentos de 61 Pacientes
author Faria, Sérgio Luis
author_facet Faria, Sérgio Luis
Murtinho, Regina Maciel
author_role author
author2 Murtinho, Regina Maciel
author2_role author
dc.contributor.author.fl_str_mv Faria, Sérgio Luis
Murtinho, Regina Maciel
dc.subject.por.fl_str_mv Doença de Hodgkin
Radioterapia
Quimioterapia
Complicações
Hodgkin's Disease
Radiotherapy
Chemotherapy
Complications
topic Doença de Hodgkin
Radioterapia
Quimioterapia
Complicações
Hodgkin's Disease
Radiotherapy
Chemotherapy
Complications
description Hodgkin's disease (HD) represents 1/3 of malignant lymphomas. It's one of the most curable cancers today, after appropriate use of radio and chemotherapy. However, these treatments may cause important complications like sterility or new cancer. Thus, it is not easy to obtain. good control of the disease with little complications. This report shows the results of 61 adult patients with HD treated at Centro de Oncologia Campinas between january/1978 and july/1985. Sixteen patients were stage I, 21 stage II, 20 stage III and 4 stage IV. Overall survival was of 92% and disease free survival was of 75% in five years, with mean follow up time of 36 months. Some difficulties were found during staging procedures due to our still limited system of social medicine. Of 32/61 (52%) patients where gonadal dysfunction was investigated, 21 (66%) did not show abnormalities. Only one patient had a secondary cancer (of the cervix), probably not related to the treatments, but further follow up is necessary, in order to obtain a better evaluation.
publishDate 2023
dc.date.none.fl_str_mv 2023-08-07
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Artigos, Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/3241
10.32635/2176-9745.RBC.1986v32n2.3241
url https://rbc.inca.gov.br/index.php/revista/article/view/3241
identifier_str_mv 10.32635/2176-9745.RBC.1986v32n2.3241
dc.language.iso.fl_str_mv por
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dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/3241/2097
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
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rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 32 No. 2 (1986): June; 95-100
Revista Brasileira de Cancerologia; Vol. 32 Núm. 2 (1986): jun.; 95-100
Revista Brasileira de Cancerologia; v. 32 n. 2 (1986): jun.; 95-100
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron:INCA
instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron_str INCA
institution INCA
reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
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