Nutritional and Functional Evaluation in Oncology and Clinical Outcome in Patients in the City of Caxias do Sul/RS

Detalhes bibliográficos
Autor(a) principal: Maurina, Ana Luísa Zanella
Data de Publicação: 2020
Outros Autores: Dell'Osbel, Rafaela Santi, Zanotti, Joana
Tipo de documento: Artigo
Idioma: por
eng
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/996
Resumo: Introduction: Malnutrition is frequent in cancer patients, impairing functionality and increasing mortality. Objective: Perform nutritional and functional assessment of patients undergoing chemotherapy and, after 6 months, evaluate the clinical outcome. Method: Observational epidemiological study, with longitudinal design, derived from a cohort followed for 6 months, formed by cancer patients undergoing chemotherapy treatment. Nutritional assessment was performed using the Body Mass Index (malnutrition; eutrophy; overweight; obesity) and the Patient-Generated Subjective Global Assessment (well nourished; moderate malnutrition or suspected malnutrition; severe malnutrition). Functional assessment was performed using manual dynamometry (adequate muscle strength; muscle weakness). The chi-square test was used to compare categorical variables and Poisson regression to identify the prevalence ratios and 95% confidence intervals. Results: Of the 208 investigated, 55.3% were elderly. There was a significant difference in the results of the nutritional assessment methods (p≤0.0001). Also, most patients with muscle weakness were not malnourished (p=0.013; p≤0.001). After 6 months, 68.4% of deaths were in malnourished patients (p≤0.0001). Advanced age (p=0.018; p=0.010) and muscle weakness (p=0.039; p=0.002) were associated with malnutrition. Conclusion: Most patients were not malnourished, although most of them had reduced functional capacity. Nutritional assessment methods differed from each other. After 6 months, patients who died had 2 times more chance of malnutrition.
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spelling Nutritional and Functional Evaluation in Oncology and Clinical Outcome in Patients in the City of Caxias do Sul/RSEvaluación Nutricional y Funcional en Oncología y Resultados Clínicos en Pacientes de la Ciudad de Caxias do Sul/RSAvaliação Nutricional e Funcional em Oncologia e Desfecho Clínico em Pacientes da Cidade de Caxias do Sul/RSNeoplasias/tratamento farmacológicoEstado NutricionalDesnutriçãoDinamômetro de Força MuscularNeoplasms/drug therapyNutritional StatusMalnutritionMuscle Strength DynamometerNeoplasias/tratamiento farmacológicoEstado NutricionalDesnutriciónDinamómetro de Fuerza MuscularIntroduction: Malnutrition is frequent in cancer patients, impairing functionality and increasing mortality. Objective: Perform nutritional and functional assessment of patients undergoing chemotherapy and, after 6 months, evaluate the clinical outcome. Method: Observational epidemiological study, with longitudinal design, derived from a cohort followed for 6 months, formed by cancer patients undergoing chemotherapy treatment. Nutritional assessment was performed using the Body Mass Index (malnutrition; eutrophy; overweight; obesity) and the Patient-Generated Subjective Global Assessment (well nourished; moderate malnutrition or suspected malnutrition; severe malnutrition). Functional assessment was performed using manual dynamometry (adequate muscle strength; muscle weakness). The chi-square test was used to compare categorical variables and Poisson regression to identify the prevalence ratios and 95% confidence intervals. Results: Of the 208 investigated, 55.3% were elderly. There was a significant difference in the results of the nutritional assessment methods (p≤0.0001). Also, most patients with muscle weakness were not malnourished (p=0.013; p≤0.001). After 6 months, 68.4% of deaths were in malnourished patients (p≤0.0001). Advanced age (p=0.018; p=0.010) and muscle weakness (p=0.039; p=0.002) were associated with malnutrition. Conclusion: Most patients were not malnourished, although most of them had reduced functional capacity. Nutritional assessment methods differed from each other. After 6 months, patients who died had 2 times more chance of malnutrition.Introducción: La desnutricion es comun en pacientes con cancer, afecta la funcionalidad y aumenta la mortalidad. Objetivo: Evaluacion nutricional y funcional de los pacientes sometidos a quimioterapia y, despues de seis meses, evaluar el resultado clinico. Método: Estudio epidemiologico observacional, con diseno longitudinal, derivado de una cohorte seguida durante seis meses, compuesta por pacientes con cancer sometidos a tratamiento de quimioterapia. La evaluacion nutricional se realizo utilizando el indice de masa corporal (desnutricion; eutrofia; sobrepeso; obesidad) y la evaluacion subjetiva global producida por el paciente (bien alimentada; desnutricion moderada o sospecha de desnutricion; desnutricion severa). La evaluacion funcional se realizo mediante dinamometria manual (fuerza muscular adecuada; debilidad muscular). La prueba de chi-cuadrado se utilizo para comparar las variables categoricas y la regresion de Poisson para identificar las razones de prevalencia y los intervalos de confianza del 95%. Resultados: De los 208 investigados, el 55,3% eran ancianos. Hubo una diferencia significativa en los resultados de los metodos de evaluacion nutricional (p≤0,0001). La mayoria de los pacientes con debilidad muscular no estaban desnutridos (p=0,013; p≤0,001). Despues de seis meses, el 68.4% de las muertes fueron en pacientes desnutridos (p≤0,0001). La edad avanzada (p=0,018; p=0,010) y la debilidad muscular (p=0,039; p=0,002) se asociaron con la desnutricion. Conclusión: La mayoria de los pacientes no estaban desnutridos, aunque la mayoria de ellos tenian una capacidad funcional reducida. Los metodos de evaluacion nutricional fueron diferentes. Despues de seis meses, los pacientes que murieron tenian dos veces mas posibilidades de desnutricion.Introdução: A desnutrição e frequente em pacientes oncológicos, prejudicando a funcionalidade e aumentando a mortalidade. Objetivo: Avaliação nutricional e funcional de pacientes em tratamento quimioterápico e, após seis meses, avaliar o desfecho clinico. Método: Estudo epidemiológico observacional, com delineamento longitudinal, derivado de uma coorte acompanhada por seis meses, composta por pacientes oncológicos em tratamento quimioterápico. Realizou-se a avaliação nutricional pelo índice de massa corporal (desnutrição; eutrofia; sobrepeso; obesidade) e pela avaliação subjetiva global produzida pelo paciente (bem nutrido; desnutrição moderada ou suspeita de desnutrição; desnutrido grave). A avaliação funcional foi realizada por meio da dinamometria manual (adequada forca muscular; fraqueza muscular). Utilizou-se o teste de qui-quadrado para comparação de variáveis categóricas e a regressão de Poisson para identificar as razoes de prevalência e intervalos de confiança em 95%. Resultados: Dos 208 investigados, 55,3% eram idosos e 52,4% do sexo feminino. Verificou-se diferença significativa nos resultados dos métodos de avaliação nutricional (p≤0,0001). A maioria dos pacientes com fraqueza muscular não estava com desnutrição (p=0,013; p≤0,001). Após seis meses, 68,4% dos óbitos foram em pacientes desnutridos (p≤0,0001). Idade avançada (p=0,018; p=0,010) e fraqueza muscular (p=0,039; p=0,002) foram associadas a desnutrição. Conclusão: A maioria dos pacientes não estava desnutrida, embora grande parte apresentou capacidade funcional reduzida. Os métodos de avaliação nutricional diferiram entre si. Após seis meses, pacientes que foram a óbito tinham duas vezes mais chance de desnutrição.INCA2020-06-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/99610.32635/2176-9745.RBC.2020v66n2.996Revista Brasileira de Cancerologia; Vol. 66 No. 2 (2020): Apr./May/June; e-10996Revista Brasileira de Cancerologia; Vol. 66 Núm. 2 (2020): abr./mayo/jun.; e-10996Revista Brasileira de Cancerologia; v. 66 n. 2 (2020): abr./maio/jun.; e-109962176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporenghttps://rbc.inca.gov.br/index.php/revista/article/view/996/646https://rbc.inca.gov.br/index.php/revista/article/view/996/745Copyright (c) 2020 Revista Brasileira de Cancerologiainfo:eu-repo/semantics/openAccessMaurina, Ana Luísa ZanellaDell'Osbel, Rafaela SantiZanotti, Joana2021-11-29T20:02:20Zoai:rbc.inca.gov.br:article/996Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2021-11-29T20:02:20Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Nutritional and Functional Evaluation in Oncology and Clinical Outcome in Patients in the City of Caxias do Sul/RS
Evaluación Nutricional y Funcional en Oncología y Resultados Clínicos en Pacientes de la Ciudad de Caxias do Sul/RS
Avaliação Nutricional e Funcional em Oncologia e Desfecho Clínico em Pacientes da Cidade de Caxias do Sul/RS
title Nutritional and Functional Evaluation in Oncology and Clinical Outcome in Patients in the City of Caxias do Sul/RS
spellingShingle Nutritional and Functional Evaluation in Oncology and Clinical Outcome in Patients in the City of Caxias do Sul/RS
Maurina, Ana Luísa Zanella
Neoplasias/tratamento farmacológico
Estado Nutricional
Desnutrição
Dinamômetro de Força Muscular
Neoplasms/drug therapy
Nutritional Status
Malnutrition
Muscle Strength Dynamometer
Neoplasias/tratamiento farmacológico
Estado Nutricional
Desnutrición
Dinamómetro de Fuerza Muscular
title_short Nutritional and Functional Evaluation in Oncology and Clinical Outcome in Patients in the City of Caxias do Sul/RS
title_full Nutritional and Functional Evaluation in Oncology and Clinical Outcome in Patients in the City of Caxias do Sul/RS
title_fullStr Nutritional and Functional Evaluation in Oncology and Clinical Outcome in Patients in the City of Caxias do Sul/RS
title_full_unstemmed Nutritional and Functional Evaluation in Oncology and Clinical Outcome in Patients in the City of Caxias do Sul/RS
title_sort Nutritional and Functional Evaluation in Oncology and Clinical Outcome in Patients in the City of Caxias do Sul/RS
author Maurina, Ana Luísa Zanella
author_facet Maurina, Ana Luísa Zanella
Dell'Osbel, Rafaela Santi
Zanotti, Joana
author_role author
author2 Dell'Osbel, Rafaela Santi
Zanotti, Joana
author2_role author
author
dc.contributor.author.fl_str_mv Maurina, Ana Luísa Zanella
Dell'Osbel, Rafaela Santi
Zanotti, Joana
dc.subject.por.fl_str_mv Neoplasias/tratamento farmacológico
Estado Nutricional
Desnutrição
Dinamômetro de Força Muscular
Neoplasms/drug therapy
Nutritional Status
Malnutrition
Muscle Strength Dynamometer
Neoplasias/tratamiento farmacológico
Estado Nutricional
Desnutrición
Dinamómetro de Fuerza Muscular
topic Neoplasias/tratamento farmacológico
Estado Nutricional
Desnutrição
Dinamômetro de Força Muscular
Neoplasms/drug therapy
Nutritional Status
Malnutrition
Muscle Strength Dynamometer
Neoplasias/tratamiento farmacológico
Estado Nutricional
Desnutrición
Dinamómetro de Fuerza Muscular
description Introduction: Malnutrition is frequent in cancer patients, impairing functionality and increasing mortality. Objective: Perform nutritional and functional assessment of patients undergoing chemotherapy and, after 6 months, evaluate the clinical outcome. Method: Observational epidemiological study, with longitudinal design, derived from a cohort followed for 6 months, formed by cancer patients undergoing chemotherapy treatment. Nutritional assessment was performed using the Body Mass Index (malnutrition; eutrophy; overweight; obesity) and the Patient-Generated Subjective Global Assessment (well nourished; moderate malnutrition or suspected malnutrition; severe malnutrition). Functional assessment was performed using manual dynamometry (adequate muscle strength; muscle weakness). The chi-square test was used to compare categorical variables and Poisson regression to identify the prevalence ratios and 95% confidence intervals. Results: Of the 208 investigated, 55.3% were elderly. There was a significant difference in the results of the nutritional assessment methods (p≤0.0001). Also, most patients with muscle weakness were not malnourished (p=0.013; p≤0.001). After 6 months, 68.4% of deaths were in malnourished patients (p≤0.0001). Advanced age (p=0.018; p=0.010) and muscle weakness (p=0.039; p=0.002) were associated with malnutrition. Conclusion: Most patients were not malnourished, although most of them had reduced functional capacity. Nutritional assessment methods differed from each other. After 6 months, patients who died had 2 times more chance of malnutrition.
publishDate 2020
dc.date.none.fl_str_mv 2020-06-12
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Artigos, Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/996
10.32635/2176-9745.RBC.2020v66n2.996
url https://rbc.inca.gov.br/index.php/revista/article/view/996
identifier_str_mv 10.32635/2176-9745.RBC.2020v66n2.996
dc.language.iso.fl_str_mv por
eng
language por
eng
dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/996/646
https://rbc.inca.gov.br/index.php/revista/article/view/996/745
dc.rights.driver.fl_str_mv Copyright (c) 2020 Revista Brasileira de Cancerologia
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2020 Revista Brasileira de Cancerologia
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 66 No. 2 (2020): Apr./May/June; e-10996
Revista Brasileira de Cancerologia; Vol. 66 Núm. 2 (2020): abr./mayo/jun.; e-10996
Revista Brasileira de Cancerologia; v. 66 n. 2 (2020): abr./maio/jun.; e-10996
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron:INCA
instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron_str INCA
institution INCA
reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
repository.mail.fl_str_mv rbc@inca.gov.br
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