Transcutaneous Electrical Stimulation, Interferential Current and Photobiomodulation May Lead to the Recurrence of Breast Cancer in Rats?

Detalhes bibliográficos
Autor(a) principal: Rezende, Laura Ferreira de
Data de Publicação: 2022
Outros Autores: da Silva Costa, Eunice Cristina, Lenzi, Juliana, Carvalho, Regiane Luz, Vilas Boas, Vanessa Fonseca
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/2383
Resumo: Introduction: Transcutaneous electrical nerve stimulation (TENS), interferential current therapy (IFC) and photobiomodulation therapy (PBMT) have been used in the management of cancer-related pain in adults. However, there are still some controversy regarding the effects of this therapy on tumor cells that may remain after cancer treatment. Objective: To evaluate the risk of recurrence of breast cancer in rats when using TENS, IFC or PBMT. Method: An experimental, randomized, controlled and cross-sectional study. With 90 days of age, 7,12-dimetylbenz(a)anthracene (7,12-DMBA) was administered to rats by gastric gavage to induce mammary cancer. After 120 days the mammary glands of the rats belonging to the group with mammary cancer were removed. Results: 39 female Sprague-Dawley rats were studied: 9 rats without induction of mammary carcinoma; 9 rats with induction of mammary carcinoma and without surgery; 9 rats with induction of mammary carcinoma with surgery and placebo application of TENS, IFC, PBMT; 9 rats with induction of mammary carcinoma, surgery and the application of TENS, IFC and PBMT. Conclusion: This study demonstrated that there was local recurrence of tumors in rats that were stimulated with TENS or IFC, however no evidence of local recurrence with PBMT.
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spelling Transcutaneous Electrical Stimulation, Interferential Current and Photobiomodulation May Lead to the Recurrence of Breast Cancer in Rats?¿La Estimulación Eléctrica Transcutánea, la Corriente Interferencial y la Fotobiomodulación pueden Provocar la Recurrencia del Cáncer de Mama en Ratas?Estimulação Elétrica Transcutânea, Corrente Interferencial e Fotobiomodulação podem levar à Recorrência do Câncer de Mama em Ratas? transcutaneous electric nerve stimulationelectric stimulation therapylow-level light therapyphysical therapy modalitiesbreast neoplasmsestimulação elétrica nervosa transcutâneaterapia por estimulação elétricaterapia com luz de baixa intensidademodalidades de fisioterapianeoplasias da mamaestimulación eléctrica transcutánea del nervioterapia por estimulación eléctricaterapia por luz de baja intensidadmodalidades de fisioterapianeoplasias de la mamaIntroduction: Transcutaneous electrical nerve stimulation (TENS), interferential current therapy (IFC) and photobiomodulation therapy (PBMT) have been used in the management of cancer-related pain in adults. However, there are still some controversy regarding the effects of this therapy on tumor cells that may remain after cancer treatment. Objective: To evaluate the risk of recurrence of breast cancer in rats when using TENS, IFC or PBMT. Method: An experimental, randomized, controlled and cross-sectional study. With 90 days of age, 7,12-dimetylbenz(a)anthracene (7,12-DMBA) was administered to rats by gastric gavage to induce mammary cancer. After 120 days the mammary glands of the rats belonging to the group with mammary cancer were removed. Results: 39 female Sprague-Dawley rats were studied: 9 rats without induction of mammary carcinoma; 9 rats with induction of mammary carcinoma and without surgery; 9 rats with induction of mammary carcinoma with surgery and placebo application of TENS, IFC, PBMT; 9 rats with induction of mammary carcinoma, surgery and the application of TENS, IFC and PBMT. Conclusion: This study demonstrated that there was local recurrence of tumors in rats that were stimulated with TENS or IFC, however no evidence of local recurrence with PBMT.Introducción: Estimulación nerviosa eléctrica transcutánea (TENS), interferencial corriente (IFC) y la terapia de fotobiomodulacion (PBMT) en el tratamiento del dolor relacionado con el cáncer en adultos. Sin embargo, todavía quedan algunas controversias sobre los efectos de esta terapia en las células tumorales que pueden permanecer después del tratamiento del cáncer. Objetivo: Evaluar el riesgo de recurrencia del cáncer de mama en ratos cuando se usa TENS, IFC o PBMT. Método: Estudio experimental, aleatorizado, controlado y transversal. Con 90 días de edad, se administro 7,12-dimetilbenz(a)antraceno (7,12-DMBA) a ratos por sonda gástrica para inducir cáncer de mama. Después de 120 días, las glándulas mamarias de las ratas pertenecientes al grupo con cáncer de mama fueron extraídas. Resultados: Se estudiaron 39 ratos-hembras Sprague-Dawley: nueve ratos sin inducción de carcinoma de mama; nueve ratos con inducción de carcinoma mamario y sin cirugía; nueve ratos con inducción de carcinoma mamario con cirugía y placebo aplicación de TENS, IFC, PBMT; nueve ratos con inducción de carcinoma mamario, cirugía y la aplicación de TENS, IFC y PBMT. Conclusión: Este estudio demostró que hubo recurrencia local de tumores en ratos que fueron estimulados con TENS o IFC, sin embargo, no hay evidencia de recurrencia local con PBMT.Introdução: Estimulação elétrica nervosa transcutânea (TENS), corrente interferencial (IFC) e fotobiomodulação (PBMT) são usadas no tratamento da dor relacionada ao câncer em adultos. No entanto, ainda existem algumas controvérsias sobre os efeitos dessa terapia nas células tumorais que podem permanecer após o tratamento do câncer. Objetivo: Avaliar o risco de recorrência de câncer de mama em ratos ao usar TENS, IFC ou PBMT. Método: Estudo experimental, randomizado, controlado e transversal. Com 90 dias de idade, 7,12-dimetilbenz(a)antraceno (7,12-DMBA) foi administrado em ratos por gavagem gástrica para induzir câncer mamário. Após 120 dias, as glândulas mamarias das ratas pertencentes ao grupo com câncer mamário foram retiradas. Resultados: Foram estudados 39 ratos-fêmeas Sprague-Dawley: nove ratos sem indução de carcinoma mamário; nove ratos com indução de carcinoma mamário e sem cirurgia; nove ratos com indução de carcinoma mamário com cirurgia e placebo, aplicação de TENS, IFC, PBMT; nove ratos com indução de carcinoma mamário, cirurgia e aplicação de TENS, IFC e PBMT. Conclusão: Este estudo demonstrou que houve recorrência local de tumores em ratos que foram estimulados com TENS ou IFC, no entanto, nenhuma evidencia de recorrência local com PBMT.INCA2022-07-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdftext/htmlhttps://rbc.inca.gov.br/index.php/revista/article/view/238310.32635/2176-9745.RBC.2022v68n3.2383Revista Brasileira de Cancerologia; Vol. 68 No. 3 (2022): July/Aug./Sept.; e-022383Revista Brasileira de Cancerologia; Vol. 68 Núm. 3 (2022): jul./ago./sept; e-022383Revista Brasileira de Cancerologia; v. 68 n. 3 (2022): jul./ago./set.; e-0223832176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAenghttps://rbc.inca.gov.br/index.php/revista/article/view/2383/1795https://rbc.inca.gov.br/index.php/revista/article/view/2383/1917Copyright (c) 2022 Revista Brasileira de Cancerologiahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessRezende, Laura Ferreira de da Silva Costa, Eunice CristinaLenzi, Juliana Carvalho, Regiane Luz Vilas Boas, Vanessa Fonseca 2022-09-13T14:41:34Zoai:rbc.inca.gov.br:article/2383Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2022-09-13T14:41:34Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Transcutaneous Electrical Stimulation, Interferential Current and Photobiomodulation May Lead to the Recurrence of Breast Cancer in Rats?
¿La Estimulación Eléctrica Transcutánea, la Corriente Interferencial y la Fotobiomodulación pueden Provocar la Recurrencia del Cáncer de Mama en Ratas?
Estimulação Elétrica Transcutânea, Corrente Interferencial e Fotobiomodulação podem levar à Recorrência do Câncer de Mama em Ratas?
title Transcutaneous Electrical Stimulation, Interferential Current and Photobiomodulation May Lead to the Recurrence of Breast Cancer in Rats?
spellingShingle Transcutaneous Electrical Stimulation, Interferential Current and Photobiomodulation May Lead to the Recurrence of Breast Cancer in Rats?
Rezende, Laura Ferreira de
transcutaneous electric nerve stimulation
electric stimulation therapy
low-level light therapy
physical therapy modalities
breast neoplasms
estimulação elétrica nervosa transcutânea
terapia por estimulação elétrica
terapia com luz de baixa intensidade
modalidades de fisioterapia
neoplasias da mama
estimulación eléctrica transcutánea del nervio
terapia por estimulación eléctrica
terapia por luz de baja intensidad
modalidades de fisioterapia
neoplasias de la mama
title_short Transcutaneous Electrical Stimulation, Interferential Current and Photobiomodulation May Lead to the Recurrence of Breast Cancer in Rats?
title_full Transcutaneous Electrical Stimulation, Interferential Current and Photobiomodulation May Lead to the Recurrence of Breast Cancer in Rats?
title_fullStr Transcutaneous Electrical Stimulation, Interferential Current and Photobiomodulation May Lead to the Recurrence of Breast Cancer in Rats?
title_full_unstemmed Transcutaneous Electrical Stimulation, Interferential Current and Photobiomodulation May Lead to the Recurrence of Breast Cancer in Rats?
title_sort Transcutaneous Electrical Stimulation, Interferential Current and Photobiomodulation May Lead to the Recurrence of Breast Cancer in Rats?
author Rezende, Laura Ferreira de
author_facet Rezende, Laura Ferreira de
da Silva Costa, Eunice Cristina
Lenzi, Juliana
Carvalho, Regiane Luz
Vilas Boas, Vanessa Fonseca
author_role author
author2 da Silva Costa, Eunice Cristina
Lenzi, Juliana
Carvalho, Regiane Luz
Vilas Boas, Vanessa Fonseca
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Rezende, Laura Ferreira de
da Silva Costa, Eunice Cristina
Lenzi, Juliana
Carvalho, Regiane Luz
Vilas Boas, Vanessa Fonseca
dc.subject.por.fl_str_mv transcutaneous electric nerve stimulation
electric stimulation therapy
low-level light therapy
physical therapy modalities
breast neoplasms
estimulação elétrica nervosa transcutânea
terapia por estimulação elétrica
terapia com luz de baixa intensidade
modalidades de fisioterapia
neoplasias da mama
estimulación eléctrica transcutánea del nervio
terapia por estimulación eléctrica
terapia por luz de baja intensidad
modalidades de fisioterapia
neoplasias de la mama
topic transcutaneous electric nerve stimulation
electric stimulation therapy
low-level light therapy
physical therapy modalities
breast neoplasms
estimulação elétrica nervosa transcutânea
terapia por estimulação elétrica
terapia com luz de baixa intensidade
modalidades de fisioterapia
neoplasias da mama
estimulación eléctrica transcutánea del nervio
terapia por estimulación eléctrica
terapia por luz de baja intensidad
modalidades de fisioterapia
neoplasias de la mama
description Introduction: Transcutaneous electrical nerve stimulation (TENS), interferential current therapy (IFC) and photobiomodulation therapy (PBMT) have been used in the management of cancer-related pain in adults. However, there are still some controversy regarding the effects of this therapy on tumor cells that may remain after cancer treatment. Objective: To evaluate the risk of recurrence of breast cancer in rats when using TENS, IFC or PBMT. Method: An experimental, randomized, controlled and cross-sectional study. With 90 days of age, 7,12-dimetylbenz(a)anthracene (7,12-DMBA) was administered to rats by gastric gavage to induce mammary cancer. After 120 days the mammary glands of the rats belonging to the group with mammary cancer were removed. Results: 39 female Sprague-Dawley rats were studied: 9 rats without induction of mammary carcinoma; 9 rats with induction of mammary carcinoma and without surgery; 9 rats with induction of mammary carcinoma with surgery and placebo application of TENS, IFC, PBMT; 9 rats with induction of mammary carcinoma, surgery and the application of TENS, IFC and PBMT. Conclusion: This study demonstrated that there was local recurrence of tumors in rats that were stimulated with TENS or IFC, however no evidence of local recurrence with PBMT.
publishDate 2022
dc.date.none.fl_str_mv 2022-07-04
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Artigos, Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/2383
10.32635/2176-9745.RBC.2022v68n3.2383
url https://rbc.inca.gov.br/index.php/revista/article/view/2383
identifier_str_mv 10.32635/2176-9745.RBC.2022v68n3.2383
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/2383/1795
https://rbc.inca.gov.br/index.php/revista/article/view/2383/1917
dc.rights.driver.fl_str_mv Copyright (c) 2022 Revista Brasileira de Cancerologia
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2022 Revista Brasileira de Cancerologia
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
text/html
dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 68 No. 3 (2022): July/Aug./Sept.; e-022383
Revista Brasileira de Cancerologia; Vol. 68 Núm. 3 (2022): jul./ago./sept; e-022383
Revista Brasileira de Cancerologia; v. 68 n. 3 (2022): jul./ago./set.; e-022383
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron:INCA
instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron_str INCA
institution INCA
reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
repository.mail.fl_str_mv rbc@inca.gov.br
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