Colorectal Carcinoma in Young Patients

Detalhes bibliográficos
Autor(a) principal: Rêgo, Ana Graziela Soares
Data de Publicação: 2012
Outros Autores: Borges, Isabel Cristina Vieira, Valença, Rodrigo José de Vasconcelos, Teles, João Batista Mendes, Pinto, Lucielma Salmito Soares
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Brasileira de Cancerologia (Online)
Texto Completo: https://rbc.inca.gov.br/index.php/revista/article/view/616
Resumo: Introduction: Colorectal carcinoma is hardly found in individuals below 50 years of age, and there are still controversies regarding its behavior and prognosis. Objective: To evaluate the epidemiological, clinical, histopathological and treatment of patients with colorectal carcinoma, comparing the age groups up to 50 years and older than 50 years. Method: This is a descriptive study, which examined records of 505 patients with colorectal carcinoma, treated from January 1998 to December 2008. Clinical and pathological parameters were collected. Results: Individuals aged 50 years or less accounted for 26.53% of the sample and there was no gender predilection. Change in bowel habits such as initial complaint to the physical examination and anemia were significantly more common in the younger group. Patients aged 50 years or younger also showed more advanced lymph nodes staging, higher incidence of squamous cell or neuroendocrine carcinoma and worse histopathological differentiation, as well as increased local recurrence, despite a higher rate of surgical treatment and chemotherapy. Conclusion: The colorectal carcinomas in younger patients were more aggressive and undifferentiated. The complaints, even from young patients, should be promptly investigated to enable early diagnosis and a higher chance of cure for patients with colorectal carcinoma.  
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spelling Colorectal Carcinoma in Young PatientsEl Cáncer Colorrectal en Pacientes JóvenesCâncer Colorretal em Pacientes JovensNeoplasias Colorretais/epidemiologiaEpidemiologia DescritivaEstadiamento de NeoplasiasAdultoMeia-IdadeEstudo ComparativoColorectal Neoplasms/epidemiologyEpidemiology, DescriptiveNeoplasm StagingAdultMiddle AgedComparative StudyNeoplasias Colorrectales/epidemiologíaEpidemiología DescriptivaEstadificación de NeoplasiasAdultoMediana EdadEstudio ComparativoIntroduction: Colorectal carcinoma is hardly found in individuals below 50 years of age, and there are still controversies regarding its behavior and prognosis. Objective: To evaluate the epidemiological, clinical, histopathological and treatment of patients with colorectal carcinoma, comparing the age groups up to 50 years and older than 50 years. Method: This is a descriptive study, which examined records of 505 patients with colorectal carcinoma, treated from January 1998 to December 2008. Clinical and pathological parameters were collected. Results: Individuals aged 50 years or less accounted for 26.53% of the sample and there was no gender predilection. Change in bowel habits such as initial complaint to the physical examination and anemia were significantly more common in the younger group. Patients aged 50 years or younger also showed more advanced lymph nodes staging, higher incidence of squamous cell or neuroendocrine carcinoma and worse histopathological differentiation, as well as increased local recurrence, despite a higher rate of surgical treatment and chemotherapy. Conclusion: The colorectal carcinomas in younger patients were more aggressive and undifferentiated. The complaints, even from young patients, should be promptly investigated to enable early diagnosis and a higher chance of cure for patients with colorectal carcinoma.  Introducción: El cáncer colorrectal suele ser poco frecuente en personas menores de 50 años, aún existen controversias em cuanto a su comportamiento y el pronóstico. Objetivo: Evaluar los aspectos epidemiológicos, clínicos, histopatológicos y tratamiento de pacientes con cáncer colorrectal, en la comparación de los grupos de edad hasta 50 años y mayores de 50 años. Método: Se realizó un estudio descriptivo, que han sido examinados los registros hospitalarios de 505 pacientes con cáncer colorrectal, tratados entre enero de 1998 a diciembre 2008. Parámetros clínicos y histopatológicos han sido recogidos. Resultados: Las personas con edad hasta 50 años representaban el 26,53% de la muestra y no hubo predilección por el género. Cambio en los hábitos intestinales, como queja inicial de la exploración física y la anemia han sido significativamente más frecuentes en el grupo más joven. Los pacientes de hasta 50 años también han exhibido estadiamiento linfonodo más avanzado, mayor incidencia de carcinoma de espinocelular o neuroendrocino y peor diferenciación histopatológica, así como la mayor recurrencia local, a pesar de una mayor tasa de tratamiento quirúrgico y quimioterapia. Conclusión: El cáncer colorrectal en pacientes con edad hasta 50 años se ha mostrado más agresivo y no diferenciado. Las quejas, incluso de los pacientes jóvenes, deben ser investigadas con prontitud a fin de posibilitar un diagnóstico precoz y una mayor posibilidad de curación para los pacientes con cáncer colorrectal.    Introdução: O câncer colorretal costuma ser pouco frequente em indivíduos abaixo dos 50 anos, persistindo ainda controvérsias quanto ao seu comportamento e prognóstico. Objetivo: Avaliar as características epidemiológicas, clínicas, histopatológicas e terapêuticas de pacientes com câncer colorretal, comparando os grupos de faixa etária até 50 anos e idade superior a 50 anos. Método: Trata-se de um estudo descritivo, em que foram analisados prontuários de 505 pacientes com câncer colorretal, atendidos de janeiro de 1998 a dezembro de 2008. Parâmetros clínicos e histopatológicos foram coletados. Resultados: Os indivíduos com idade ate 50 anos corresponderam a 26,53% da amostra e não houve predileção por gênero. Alteração no hábito intestinal como queixa inicial e anemia ao exame físico foram significativamente mais comuns no grupo mais jovem. Os pacientes ate 50 anos exibiram também estadiamento linfonodal mais avançado, maior ocorrência de carcinoma espinocelular ou neuroendócrino e pior diferenciação histopatologia, bem como maior recorrencial local, apesar de maior índice de tratamento cirúrgico e quimioterápico. Conclusão: O câncer colorretal em pacientes com idade ate 50 anos mostrou-se mais agressivo e indiferenciado. As queixas, mesmo dos pacientes jovens, devem ser prontamente investigadas, a fim de possibilitar o diagnóstico precoce e maior chance de cura ao paciente com câncer colorretal.    INCA2012-06-29info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigos, Avaliado pelos paresapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/61610.32635/2176-9745.RBC.2012v58n2.616Revista Brasileira de Cancerologia; Vol. 58 No. 2 (2012): Apr./May/June; 173-180Revista Brasileira de Cancerologia; Vol. 58 Núm. 2 (2012): abr./mayo/jun.; 173-180Revista Brasileira de Cancerologia; v. 58 n. 2 (2012): abr./maio/jun. ; 173-1802176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/616/385Rêgo, Ana Graziela Soares Borges, Isabel Cristina Vieira Valença, Rodrigo José de VasconcelosTeles, João Batista Mendes Pinto, Lucielma Salmito Soares info:eu-repo/semantics/openAccess2021-11-29T20:14:44Zoai:rbc.inca.gov.br:article/616Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2021-11-29T20:14:44Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
dc.title.none.fl_str_mv Colorectal Carcinoma in Young Patients
El Cáncer Colorrectal en Pacientes Jóvenes
Câncer Colorretal em Pacientes Jovens
title Colorectal Carcinoma in Young Patients
spellingShingle Colorectal Carcinoma in Young Patients
Rêgo, Ana Graziela Soares
Neoplasias Colorretais/epidemiologia
Epidemiologia Descritiva
Estadiamento de Neoplasias
Adulto
Meia-Idade
Estudo Comparativo
Colorectal Neoplasms/epidemiology
Epidemiology, Descriptive
Neoplasm Staging
Adult
Middle Aged
Comparative Study
Neoplasias Colorrectales/epidemiología
Epidemiología Descriptiva
Estadificación de Neoplasias
Adulto
Mediana Edad
Estudio Comparativo
title_short Colorectal Carcinoma in Young Patients
title_full Colorectal Carcinoma in Young Patients
title_fullStr Colorectal Carcinoma in Young Patients
title_full_unstemmed Colorectal Carcinoma in Young Patients
title_sort Colorectal Carcinoma in Young Patients
author Rêgo, Ana Graziela Soares
author_facet Rêgo, Ana Graziela Soares
Borges, Isabel Cristina Vieira
Valença, Rodrigo José de Vasconcelos
Teles, João Batista Mendes
Pinto, Lucielma Salmito Soares
author_role author
author2 Borges, Isabel Cristina Vieira
Valença, Rodrigo José de Vasconcelos
Teles, João Batista Mendes
Pinto, Lucielma Salmito Soares
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Rêgo, Ana Graziela Soares
Borges, Isabel Cristina Vieira
Valença, Rodrigo José de Vasconcelos
Teles, João Batista Mendes
Pinto, Lucielma Salmito Soares
dc.subject.por.fl_str_mv Neoplasias Colorretais/epidemiologia
Epidemiologia Descritiva
Estadiamento de Neoplasias
Adulto
Meia-Idade
Estudo Comparativo
Colorectal Neoplasms/epidemiology
Epidemiology, Descriptive
Neoplasm Staging
Adult
Middle Aged
Comparative Study
Neoplasias Colorrectales/epidemiología
Epidemiología Descriptiva
Estadificación de Neoplasias
Adulto
Mediana Edad
Estudio Comparativo
topic Neoplasias Colorretais/epidemiologia
Epidemiologia Descritiva
Estadiamento de Neoplasias
Adulto
Meia-Idade
Estudo Comparativo
Colorectal Neoplasms/epidemiology
Epidemiology, Descriptive
Neoplasm Staging
Adult
Middle Aged
Comparative Study
Neoplasias Colorrectales/epidemiología
Epidemiología Descriptiva
Estadificación de Neoplasias
Adulto
Mediana Edad
Estudio Comparativo
description Introduction: Colorectal carcinoma is hardly found in individuals below 50 years of age, and there are still controversies regarding its behavior and prognosis. Objective: To evaluate the epidemiological, clinical, histopathological and treatment of patients with colorectal carcinoma, comparing the age groups up to 50 years and older than 50 years. Method: This is a descriptive study, which examined records of 505 patients with colorectal carcinoma, treated from January 1998 to December 2008. Clinical and pathological parameters were collected. Results: Individuals aged 50 years or less accounted for 26.53% of the sample and there was no gender predilection. Change in bowel habits such as initial complaint to the physical examination and anemia were significantly more common in the younger group. Patients aged 50 years or younger also showed more advanced lymph nodes staging, higher incidence of squamous cell or neuroendocrine carcinoma and worse histopathological differentiation, as well as increased local recurrence, despite a higher rate of surgical treatment and chemotherapy. Conclusion: The colorectal carcinomas in younger patients were more aggressive and undifferentiated. The complaints, even from young patients, should be promptly investigated to enable early diagnosis and a higher chance of cure for patients with colorectal carcinoma.  
publishDate 2012
dc.date.none.fl_str_mv 2012-06-29
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Artigos, Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/616
10.32635/2176-9745.RBC.2012v58n2.616
url https://rbc.inca.gov.br/index.php/revista/article/view/616
identifier_str_mv 10.32635/2176-9745.RBC.2012v58n2.616
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dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/616/385
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dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 58 No. 2 (2012): Apr./May/June; 173-180
Revista Brasileira de Cancerologia; Vol. 58 Núm. 2 (2012): abr./mayo/jun.; 173-180
Revista Brasileira de Cancerologia; v. 58 n. 2 (2012): abr./maio/jun. ; 173-180
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron:INCA
instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron_str INCA
institution INCA
reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
repository.mail.fl_str_mv rbc@inca.gov.br
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