Hypolipidemic effect of diet supplementation with cocona (solanum sessiliforum dunal) four in hypercholesterolemic rats.
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional do INPA |
Texto Completo: | https://repositorio.inpa.gov.br/handle/1/15933 |
Resumo: | Studies with fruit and vegetables rich in dietary fber have shown lowering effects on the blood concentrations of total cholesterol (TC), acting preventively against hypercholesterolemia. The aim of this study was to analyze the chemical composition of cocona and evaluate the effect of the consumption of cocona four on lipemia of Wistar rats with hypercholesterolemia. Eight animals were used for each treatment, in 7 groups: control; 3 experimental groups with 5%, 25% and 50% of the recommended fber (AIN-93) from cocona four; 3 groups per feeding with pectin and cellulose as source of dietary fber, in the same proportions of the experimental groups. At the end of the assay, we verifed that there were not signifcant variations in the consumption of the animals and the body weight during the experiment. Treatments with cocna four were responsible for reducing the concentrations of total cholesterol (-21.6%), LDL-c (-56.8%), increasing the excretion of fecal cholesterol (+116%) and lowering the liver cholesterol (-32.1%). None of the treatments signifcantly altered the triglyceride concentrations. Treatments using pectin and cellulose show results similar to cocona. The observed results can be used in further studies aimed at the biotechnological exploitation of this fruit. © 2015, Instituto de Biociencias. All rights reserved. |
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Maia, Jeniffer Resende PatrocínioSchwertz, Maíra CássiaSousa, R. F SAguiar, Jaime Paiva LopesLima, Emerson Silva2020-05-20T19:08:46Z2020-05-20T19:08:46Z2015https://repositorio.inpa.gov.br/handle/1/1593310.1590/1983-084X/11_163Studies with fruit and vegetables rich in dietary fber have shown lowering effects on the blood concentrations of total cholesterol (TC), acting preventively against hypercholesterolemia. The aim of this study was to analyze the chemical composition of cocona and evaluate the effect of the consumption of cocona four on lipemia of Wistar rats with hypercholesterolemia. Eight animals were used for each treatment, in 7 groups: control; 3 experimental groups with 5%, 25% and 50% of the recommended fber (AIN-93) from cocona four; 3 groups per feeding with pectin and cellulose as source of dietary fber, in the same proportions of the experimental groups. At the end of the assay, we verifed that there were not signifcant variations in the consumption of the animals and the body weight during the experiment. Treatments with cocna four were responsible for reducing the concentrations of total cholesterol (-21.6%), LDL-c (-56.8%), increasing the excretion of fecal cholesterol (+116%) and lowering the liver cholesterol (-32.1%). None of the treatments signifcantly altered the triglyceride concentrations. Treatments using pectin and cellulose show results similar to cocona. The observed results can be used in further studies aimed at the biotechnological exploitation of this fruit. © 2015, Instituto de Biociencias. All rights reserved.Volume 17, Número 1, Pags. 112-119Attribution-NonCommercial-NoDerivs 3.0 Brazilhttp://creativecommons.org/licenses/by-nc-nd/3.0/br/info:eu-repo/semantics/openAccessAntilipemic AgentCelluloseCholesterolLow Density Lipoprotein CholesterolPectinAnimals ModelChemical CompositionControlled StudyDiet SupplementationDietary FiberFlourFruitHypercholesterolemiaNonhumanRatSolanumSolanum SessiliflorumAnimalsiaRattusRattus NorvegicusSolanumHypolipidemic effect of diet supplementation with cocona (solanum sessiliforum dunal) four in hypercholesterolemic rats.Efeito hipolipemiante da suplementação dietética com a farinha do cubiu (solanum sessiliforum dunal) em ratos hipercolesterolêmicosinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleRevista Brasileira de Plantas Medicinaisporreponame:Repositório Institucional do INPAinstname:Instituto Nacional de Pesquisas da Amazônia (INPA)instacron:INPAORIGINALartigo-inpa.pdfartigo-inpa.pdfapplication/pdf327339https://repositorio.inpa.gov.br/bitstream/1/15933/1/artigo-inpa.pdf3bbe635d35975beee2246ec187ec8923MD511/159332020-05-20 15:54:46.484oai:repositorio:1/15933Repositório de PublicaçõesPUBhttps://repositorio.inpa.gov.br/oai/requestopendoar:2020-05-20T19:54:46Repositório Institucional do INPA - Instituto Nacional de Pesquisas da Amazônia (INPA)false |
dc.title.en.fl_str_mv |
Hypolipidemic effect of diet supplementation with cocona (solanum sessiliforum dunal) four in hypercholesterolemic rats. |
dc.title.alternative.pt_BR.fl_str_mv |
Efeito hipolipemiante da suplementação dietética com a farinha do cubiu (solanum sessiliforum dunal) em ratos hipercolesterolêmicos |
title |
Hypolipidemic effect of diet supplementation with cocona (solanum sessiliforum dunal) four in hypercholesterolemic rats. |
spellingShingle |
Hypolipidemic effect of diet supplementation with cocona (solanum sessiliforum dunal) four in hypercholesterolemic rats. Maia, Jeniffer Resende Patrocínio Antilipemic Agent Cellulose Cholesterol Low Density Lipoprotein Cholesterol Pectin Animals Model Chemical Composition Controlled Study Diet Supplementation Dietary Fiber Flour Fruit Hypercholesterolemia Nonhuman Rat Solanum Solanum Sessiliflorum Animalsia Rattus Rattus Norvegicus Solanum |
title_short |
Hypolipidemic effect of diet supplementation with cocona (solanum sessiliforum dunal) four in hypercholesterolemic rats. |
title_full |
Hypolipidemic effect of diet supplementation with cocona (solanum sessiliforum dunal) four in hypercholesterolemic rats. |
title_fullStr |
Hypolipidemic effect of diet supplementation with cocona (solanum sessiliforum dunal) four in hypercholesterolemic rats. |
title_full_unstemmed |
Hypolipidemic effect of diet supplementation with cocona (solanum sessiliforum dunal) four in hypercholesterolemic rats. |
title_sort |
Hypolipidemic effect of diet supplementation with cocona (solanum sessiliforum dunal) four in hypercholesterolemic rats. |
author |
Maia, Jeniffer Resende Patrocínio |
author_facet |
Maia, Jeniffer Resende Patrocínio Schwertz, Maíra Cássia Sousa, R. F S Aguiar, Jaime Paiva Lopes Lima, Emerson Silva |
author_role |
author |
author2 |
Schwertz, Maíra Cássia Sousa, R. F S Aguiar, Jaime Paiva Lopes Lima, Emerson Silva |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Maia, Jeniffer Resende Patrocínio Schwertz, Maíra Cássia Sousa, R. F S Aguiar, Jaime Paiva Lopes Lima, Emerson Silva |
dc.subject.eng.fl_str_mv |
Antilipemic Agent Cellulose Cholesterol Low Density Lipoprotein Cholesterol Pectin Animals Model Chemical Composition Controlled Study Diet Supplementation Dietary Fiber Flour Fruit Hypercholesterolemia Nonhuman Rat Solanum Solanum Sessiliflorum Animalsia Rattus Rattus Norvegicus Solanum |
topic |
Antilipemic Agent Cellulose Cholesterol Low Density Lipoprotein Cholesterol Pectin Animals Model Chemical Composition Controlled Study Diet Supplementation Dietary Fiber Flour Fruit Hypercholesterolemia Nonhuman Rat Solanum Solanum Sessiliflorum Animalsia Rattus Rattus Norvegicus Solanum |
description |
Studies with fruit and vegetables rich in dietary fber have shown lowering effects on the blood concentrations of total cholesterol (TC), acting preventively against hypercholesterolemia. The aim of this study was to analyze the chemical composition of cocona and evaluate the effect of the consumption of cocona four on lipemia of Wistar rats with hypercholesterolemia. Eight animals were used for each treatment, in 7 groups: control; 3 experimental groups with 5%, 25% and 50% of the recommended fber (AIN-93) from cocona four; 3 groups per feeding with pectin and cellulose as source of dietary fber, in the same proportions of the experimental groups. At the end of the assay, we verifed that there were not signifcant variations in the consumption of the animals and the body weight during the experiment. Treatments with cocna four were responsible for reducing the concentrations of total cholesterol (-21.6%), LDL-c (-56.8%), increasing the excretion of fecal cholesterol (+116%) and lowering the liver cholesterol (-32.1%). None of the treatments signifcantly altered the triglyceride concentrations. Treatments using pectin and cellulose show results similar to cocona. The observed results can be used in further studies aimed at the biotechnological exploitation of this fruit. © 2015, Instituto de Biociencias. All rights reserved. |
publishDate |
2015 |
dc.date.issued.fl_str_mv |
2015 |
dc.date.accessioned.fl_str_mv |
2020-05-20T19:08:46Z |
dc.date.available.fl_str_mv |
2020-05-20T19:08:46Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://repositorio.inpa.gov.br/handle/1/15933 |
dc.identifier.doi.none.fl_str_mv |
10.1590/1983-084X/11_163 |
url |
https://repositorio.inpa.gov.br/handle/1/15933 |
identifier_str_mv |
10.1590/1983-084X/11_163 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.ispartof.pt_BR.fl_str_mv |
Volume 17, Número 1, Pags. 112-119 |
dc.rights.driver.fl_str_mv |
Attribution-NonCommercial-NoDerivs 3.0 Brazil http://creativecommons.org/licenses/by-nc-nd/3.0/br/ info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Attribution-NonCommercial-NoDerivs 3.0 Brazil http://creativecommons.org/licenses/by-nc-nd/3.0/br/ |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Revista Brasileira de Plantas Medicinais |
publisher.none.fl_str_mv |
Revista Brasileira de Plantas Medicinais |
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reponame:Repositório Institucional do INPA instname:Instituto Nacional de Pesquisas da Amazônia (INPA) instacron:INPA |
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Instituto Nacional de Pesquisas da Amazônia (INPA) |
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INPA |
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INPA |
reponame_str |
Repositório Institucional do INPA |
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Repositório Institucional do INPA |
bitstream.url.fl_str_mv |
https://repositorio.inpa.gov.br/bitstream/1/15933/1/artigo-inpa.pdf |
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