Chemical constituents from stems of simaba guianensis subesp. ecaudata (cronquist)

Detalhes bibliográficos
Autor(a) principal: Nunomura, Rita de Cássia Saraiva
Data de Publicação: 2012
Outros Autores: Pinto, Ângelo da Cunha, Nunomura, Sergio Massayoshi, Pohlit, Adrian Martin, Amaral, Aná Cláudia Fernandes
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional do INPA
Texto Completo: https://repositorio.inpa.gov.br/handle/1/16092
Resumo: Simaba guianensis subesp. ecaudata (Simaroubaceae) is a tree found in the Brazilian Amazon. This work describes for the first time the fractionation of stems of this species that resulted in the isolation of the cytotoxic triterpene piscidinol A, the alkaloid 9-methoxycanthin-6-one, caryophyllene oxide, also isolated for the first time from this species and a new alkaloid (6-methoxy-(9H-β-carbolin-1-il)-(Z)-2-propenoic acid). Quantification of 9-methoxycanthin-6-one in different extracts and fractions of stems of S. guianensis by high performance liquid chromatography was also performed. The concentration of 9-methoxycanthin-6-one in methanolic and aqueous extracts were inferior to the known cytotoxic concentration of this compound.
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spelling Nunomura, Rita de Cássia SaraivaPinto, Ângelo da CunhaNunomura, Sergio MassayoshiPohlit, Adrian MartinAmaral, Aná Cláudia Fernandes2020-05-24T21:19:36Z2020-05-24T21:19:36Z2012https://repositorio.inpa.gov.br/handle/1/1609210.1590/S0100-40422012001100009Simaba guianensis subesp. ecaudata (Simaroubaceae) is a tree found in the Brazilian Amazon. This work describes for the first time the fractionation of stems of this species that resulted in the isolation of the cytotoxic triterpene piscidinol A, the alkaloid 9-methoxycanthin-6-one, caryophyllene oxide, also isolated for the first time from this species and a new alkaloid (6-methoxy-(9H-β-carbolin-1-il)-(Z)-2-propenoic acid). Quantification of 9-methoxycanthin-6-one in different extracts and fractions of stems of S. guianensis by high performance liquid chromatography was also performed. The concentration of 9-methoxycanthin-6-one in methanolic and aqueous extracts were inferior to the known cytotoxic concentration of this compound.Volume 35, Número 11, Pags. 2153-2158Attribution-NonCommercial-NoDerivs 3.0 Brazilhttp://creativecommons.org/licenses/by-nc-nd/3.0/br/info:eu-repo/semantics/openAccessChemical constituents from stems of simaba guianensis subesp. ecaudata (cronquist)Constituintes químicos dos galhos de simaba guianensis subesp. ecaudata (cronquist)info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleQuímica Novaporreponame:Repositório Institucional do INPAinstname:Instituto Nacional de Pesquisas da Amazônia (INPA)instacron:INPAORIGINALartigo-inpa.pdfartigo-inpa.pdfapplication/pdf545221https://repositorio.inpa.gov.br/bitstream/1/16092/1/artigo-inpa.pdf53bc348e7db7ee692c1ca78558883d09MD511/160922020-06-30 15:12:21.113oai:repositorio:1/16092Repositório de PublicaçõesPUBhttps://repositorio.inpa.gov.br/oai/requestopendoar:2020-06-30T19:12:21Repositório Institucional do INPA - Instituto Nacional de Pesquisas da Amazônia (INPA)false
dc.title.en.fl_str_mv Chemical constituents from stems of simaba guianensis subesp. ecaudata (cronquist)
dc.title.alternative.pt_BR.fl_str_mv Constituintes químicos dos galhos de simaba guianensis subesp. ecaudata (cronquist)
title Chemical constituents from stems of simaba guianensis subesp. ecaudata (cronquist)
spellingShingle Chemical constituents from stems of simaba guianensis subesp. ecaudata (cronquist)
Nunomura, Rita de Cássia Saraiva
title_short Chemical constituents from stems of simaba guianensis subesp. ecaudata (cronquist)
title_full Chemical constituents from stems of simaba guianensis subesp. ecaudata (cronquist)
title_fullStr Chemical constituents from stems of simaba guianensis subesp. ecaudata (cronquist)
title_full_unstemmed Chemical constituents from stems of simaba guianensis subesp. ecaudata (cronquist)
title_sort Chemical constituents from stems of simaba guianensis subesp. ecaudata (cronquist)
author Nunomura, Rita de Cássia Saraiva
author_facet Nunomura, Rita de Cássia Saraiva
Pinto, Ângelo da Cunha
Nunomura, Sergio Massayoshi
Pohlit, Adrian Martin
Amaral, Aná Cláudia Fernandes
author_role author
author2 Pinto, Ângelo da Cunha
Nunomura, Sergio Massayoshi
Pohlit, Adrian Martin
Amaral, Aná Cláudia Fernandes
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Nunomura, Rita de Cássia Saraiva
Pinto, Ângelo da Cunha
Nunomura, Sergio Massayoshi
Pohlit, Adrian Martin
Amaral, Aná Cláudia Fernandes
description Simaba guianensis subesp. ecaudata (Simaroubaceae) is a tree found in the Brazilian Amazon. This work describes for the first time the fractionation of stems of this species that resulted in the isolation of the cytotoxic triterpene piscidinol A, the alkaloid 9-methoxycanthin-6-one, caryophyllene oxide, also isolated for the first time from this species and a new alkaloid (6-methoxy-(9H-β-carbolin-1-il)-(Z)-2-propenoic acid). Quantification of 9-methoxycanthin-6-one in different extracts and fractions of stems of S. guianensis by high performance liquid chromatography was also performed. The concentration of 9-methoxycanthin-6-one in methanolic and aqueous extracts were inferior to the known cytotoxic concentration of this compound.
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2020-05-24T21:19:36Z
dc.date.available.fl_str_mv 2020-05-24T21:19:36Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://repositorio.inpa.gov.br/handle/1/16092
dc.identifier.doi.none.fl_str_mv 10.1590/S0100-40422012001100009
url https://repositorio.inpa.gov.br/handle/1/16092
identifier_str_mv 10.1590/S0100-40422012001100009
dc.language.iso.fl_str_mv por
language por
dc.relation.ispartof.pt_BR.fl_str_mv Volume 35, Número 11, Pags. 2153-2158
dc.rights.driver.fl_str_mv Attribution-NonCommercial-NoDerivs 3.0 Brazil
http://creativecommons.org/licenses/by-nc-nd/3.0/br/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution-NonCommercial-NoDerivs 3.0 Brazil
http://creativecommons.org/licenses/by-nc-nd/3.0/br/
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Química Nova
publisher.none.fl_str_mv Química Nova
dc.source.none.fl_str_mv reponame:Repositório Institucional do INPA
instname:Instituto Nacional de Pesquisas da Amazônia (INPA)
instacron:INPA
instname_str Instituto Nacional de Pesquisas da Amazônia (INPA)
instacron_str INPA
institution INPA
reponame_str Repositório Institucional do INPA
collection Repositório Institucional do INPA
bitstream.url.fl_str_mv https://repositorio.inpa.gov.br/bitstream/1/16092/1/artigo-inpa.pdf
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repository.name.fl_str_mv Repositório Institucional do INPA - Instituto Nacional de Pesquisas da Amazônia (INPA)
repository.mail.fl_str_mv
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