Constituintes químicos dos galhos de Simaba guianensis subesp. ecaudata (Cronquist)

Detalhes bibliográficos
Autor(a) principal: Nunomura,Rita de Cássia Saraiva
Data de Publicação: 2012
Outros Autores: Pinto,Angelo C., Nunomura,Sergio Massayoshi, Pohlit,Adrian Martin, Amaral,Ana Cláudia Fernandes
Tipo de documento: Artigo
Idioma: por
Título da fonte: Química Nova (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422012001100009
Resumo: Simaba guianensis subesp. ecaudata (Simaroubaceae) is a tree found in the Brazilian Amazon. This work describes for the first time the fractionation of stems of this species that resulted in the isolation of the cytotoxic triterpene piscidinol A, the alkaloid 9-methoxycanthin-6-one, caryophyllene oxide, also isolated for the first time from this species and a new alkaloid (6-methoxy-(9H-β-carbolin-1-il)-(Z)-2-propenoic acid). Quantification of 9-methoxycanthin-6-one in different extracts and fractions of stems of S. guianensis by high performance liquid chromatography was also performed. The concentration of 9-methoxycanthin-6-one in methanolic and aqueous extracts were inferior to the known cytotoxic concentration of this compound.
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spelling Constituintes químicos dos galhos de Simaba guianensis subesp. ecaudata (Cronquist)piscidinol A9-methoxycanthin-6-oneHPLCSimaba guianensis subesp. ecaudata (Simaroubaceae) is a tree found in the Brazilian Amazon. This work describes for the first time the fractionation of stems of this species that resulted in the isolation of the cytotoxic triterpene piscidinol A, the alkaloid 9-methoxycanthin-6-one, caryophyllene oxide, also isolated for the first time from this species and a new alkaloid (6-methoxy-(9H-β-carbolin-1-il)-(Z)-2-propenoic acid). Quantification of 9-methoxycanthin-6-one in different extracts and fractions of stems of S. guianensis by high performance liquid chromatography was also performed. The concentration of 9-methoxycanthin-6-one in methanolic and aqueous extracts were inferior to the known cytotoxic concentration of this compound.Sociedade Brasileira de Química2012-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422012001100009Química Nova v.35 n.11 2012reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0100-40422012001100009info:eu-repo/semantics/openAccessNunomura,Rita de Cássia SaraivaPinto,Angelo C.Nunomura,Sergio MassayoshiPohlit,Adrian MartinAmaral,Ana Cláudia Fernandespor2012-11-30T00:00:00Zoai:scielo:S0100-40422012001100009Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2012-11-30T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Constituintes químicos dos galhos de Simaba guianensis subesp. ecaudata (Cronquist)
title Constituintes químicos dos galhos de Simaba guianensis subesp. ecaudata (Cronquist)
spellingShingle Constituintes químicos dos galhos de Simaba guianensis subesp. ecaudata (Cronquist)
Nunomura,Rita de Cássia Saraiva
piscidinol A
9-methoxycanthin-6-one
HPLC
title_short Constituintes químicos dos galhos de Simaba guianensis subesp. ecaudata (Cronquist)
title_full Constituintes químicos dos galhos de Simaba guianensis subesp. ecaudata (Cronquist)
title_fullStr Constituintes químicos dos galhos de Simaba guianensis subesp. ecaudata (Cronquist)
title_full_unstemmed Constituintes químicos dos galhos de Simaba guianensis subesp. ecaudata (Cronquist)
title_sort Constituintes químicos dos galhos de Simaba guianensis subesp. ecaudata (Cronquist)
author Nunomura,Rita de Cássia Saraiva
author_facet Nunomura,Rita de Cássia Saraiva
Pinto,Angelo C.
Nunomura,Sergio Massayoshi
Pohlit,Adrian Martin
Amaral,Ana Cláudia Fernandes
author_role author
author2 Pinto,Angelo C.
Nunomura,Sergio Massayoshi
Pohlit,Adrian Martin
Amaral,Ana Cláudia Fernandes
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Nunomura,Rita de Cássia Saraiva
Pinto,Angelo C.
Nunomura,Sergio Massayoshi
Pohlit,Adrian Martin
Amaral,Ana Cláudia Fernandes
dc.subject.por.fl_str_mv piscidinol A
9-methoxycanthin-6-one
HPLC
topic piscidinol A
9-methoxycanthin-6-one
HPLC
description Simaba guianensis subesp. ecaudata (Simaroubaceae) is a tree found in the Brazilian Amazon. This work describes for the first time the fractionation of stems of this species that resulted in the isolation of the cytotoxic triterpene piscidinol A, the alkaloid 9-methoxycanthin-6-one, caryophyllene oxide, also isolated for the first time from this species and a new alkaloid (6-methoxy-(9H-β-carbolin-1-il)-(Z)-2-propenoic acid). Quantification of 9-methoxycanthin-6-one in different extracts and fractions of stems of S. guianensis by high performance liquid chromatography was also performed. The concentration of 9-methoxycanthin-6-one in methanolic and aqueous extracts were inferior to the known cytotoxic concentration of this compound.
publishDate 2012
dc.date.none.fl_str_mv 2012-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422012001100009
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422012001100009
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv 10.1590/S0100-40422012001100009
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Química Nova v.35 n.11 2012
reponame:Química Nova (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Química Nova (Online)
collection Química Nova (Online)
repository.name.fl_str_mv Química Nova (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv quimicanova@sbq.org.br
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