The complete genome sequence of Chromobacterium violaceum reveals remarkable and exploitable bacterial adaptability

• Autor(a) principal: Vasconcelos, Ana Tereza
• Data de Publicação: 2003
• Outros Autores: De-Almeida, Darcy Fontoura, Hungría, Mariangela, Guimarães, Cláudia Teixeira, Antônio, Regina Vasconcellos, Almeida, Francisca Cunha, Almeida, Luiz G.P., Almeida, Rosana G. de, Alves-Gomes, José Antônio, Andrade, Elizabeth Mazoni, Araripe, Júlia Rolão, Araújo, Magnólia Fernandes Florêncio de, Astolfi-Filho, Spártaco A.T., Azevedo, Vasco Ariston Carvalho, Baptista, Alessandra Jorge, Bataus, Luiz Artur Mendes, Batista, Jacqueline da Silva, Beló, André, Van Den Berg, Cássio, Bogo, Maurício Reis, Bonatto, Sandro L., Bordignon, Juliano, Brígido, Marcelo Macedo, Brito, Cristiana Ferreira Alves de, Brocchi, Marcelo, Burity, Hélio Almeida, Camargo, Anamaria A., Cardoso, Divina das Dôres de Paula, Carneiro, Newton Portilho, Carraro, Dirce Maria, Carvalho, Cláudia Márcia Benedetto, Mattos Cascardo, Júlio Cézar de, Cavada, B. S., Chueire, Lígia Maria Oliveira, Creczynski-Pasa, Tânia Beatriz, Cunha, Nivaldo Costa da, Fagundes, Nelson Jurandi Rosa, Falcão, Clarissa Lima, Fantinatti, Fabiana, Farias, Izeni P., Felipe, Maria Sueli Soares, Ferrari, Lilian Pereira, Ferro, Jesus Aparecido, Ferro, Maria Inês Tiraboschi, Franco, Glória Regina, Freitas, Nara Suzy Aguiar de, Furlan, Luiz Roberto, Gazzinelli, Ricardo Tostes Ostes, Gomes, Eliane Aparecida, Gonçalves, Pablo Rodrigues, Grangeiro, Thalles Barbosa, Grattapaglia, Dario, Grisard, Edmundo Carlos, Hanna, Ebert Seixas, Jardim, Sílvia Neto, Laurino, Jomar Pereira, Leoi, Lélia C.T., Agnez-Lima, Lucymara Fassarella, FÁtima Loureiro, Maria de, Lyra, Maria do Carmo Catanho Pereira de, Madeira, Humberto Maciel França, Manfio, Gilson Paulo, Queiroz Maranhão, Andrea, Martins, Wellington Santos, Zingaretti, Sônia M., Batistuzzo de Medeiros, Sìlvia Regina, Vasconcellos Meissner, Rosely de, Moreira, Miguel Ångelo Martins, Nascimento, Fabrícia F., Nicolás, Marisa Fabiana, Oliveira, Jaquelline Germano, Oliveira, Sérgio Costa, Paixão, Roger Ferreira Cury, Parente, Juliana Alves, Pedrosa, Fabio O., Pena, Sergio Danilo Junho, Pereira, José Odair, Pereira, Maristela, Pinto, Luciana Santos Rodrigues Costa, Pinto, Luciano Silva da, Porto, Jorge Ivan Rebelo, Potrich, Deise Porto, Ramalho-Neto, Cícero Eduardo, Reis, Alessandra Maria Moreira, Rigo, Liu Un, Rondinelli, Edson, do Santos, Elen Bethleen Pedraça, Santos, Fabrício Rodrigues dos, Schneider, Maria Paula Cruz, Seuánez, Héctor Nicolás, Silva, Ana Maria Rodrigues, Silva, Artur, Silva, Denise Wanderlei, Silva, Rosane A., Carmo Simões, Isabella de, Simon, Daniel, Almeida Soares, Célia Maria A. de, Soares, Renata de Bastos Ascenço, Souza, Emanuel Maltempi de, Lobo de Souza, Kelly Rose, Souza, Rangel Celso, Steffens, Maria Berenice Reynaud, Steindel, Mário R., Teixeira, Santuza Ribeiro, Ürményi, Turán Péter, Vettore, Andre Luiz, Wassem, Roseli, Zaha, Arnaldo, Simpson, Andrew John George
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional do INPA
• Texto Completo: https://repositorio.inpa.gov.br/handle/1/14862
• topic: Bacterial Enzyme; Bacterial Protein; Carrier Protein; Chitinase; Heavy Metal; Paraquat; Adaptation; Genome, Bacterial; Biotechnology; Cell Motility; Chromobacterium; Chromobacterium Violaceum; Detoxification; Energy Metabolism; Gene Sequence; Membrane Transport; Nonhuman; Nucleotide Sequence; Open Reading Frame; Pathogenicity; Priority Journal; Signal Transduction; Stress; Xenobiotic Metabolism; Bacteria (microorganisms); Chromobacterium; Chromobacterium Violaceum; Chromobacterium Violaceum; Mammalia; Negibacteria; Prokaryota

Chromobacterium violaceum is one of millions of species of free-living microorganisms that populate the soil and water in the extant areas of tropical biodiversity around the world. Its complete genome sequence reveals (i) extensive alternative pathways for energy generation, (ii) ≈500 ORFs for transport-related proteins, (iii) complex and extensive systems for stress adaptation and motility, and (iv) wide-spread utilization of quorum sensing for control of inducible systems, all of which underpin the versatility and adaptability of the organism. The genome also contains extensive but incomplete arrays of ORFs coding for proteins associated with mammalian pathogenicity, possibly involved in the occasional but often fatal cases of human C. violaceum infection. There is, in addition, a series of previously unknown but important enzymes and secondary metabolites including paraquat-inducible proteins, drug and heavy-metal-resistance proteins, multiple chitinases, and proteins for the detoxification of xenobiotics that may have biotechnological applications.