Neuroendocrine Neoplasm in Cecal Appendix: A Case Report
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Amadeus International Multidisciplinary Journal |
Texto Completo: | https://amadeusjournal.emnuvens.com.br/amadeus/article/view/84 |
Resumo: | Although neuroendocrine neoplasms are relatively uncommon entities, the appendix is a site with relatively frequent emergence of this pathology and its precise diagnosis and clinical management have been a challenge for practitioners. This paper aims to present and discuss a case report of neuroendocrine neoplasia in the appendix of a patient with acute abdomen who underwent appendectomy. A 46-year-old man referred to the Emergency Department complaining of abdominal pain in the right iliac fossa and signs of peritoneal irritation. After diagnosis of acute appendicitis, the patient underwent appendectomy. In a macroscopic analysis, an area of 1.9 cm long, hardened, irregular and yellowish shapes was noted in the distal third of the appendix. Histopathological analysis showed neoplasia consisting of invasive islands of monotonous rounded epithelioid cells, large areas of necrosis, high mitotic activity, neural and angiolymphatic invasion and extension to adipose tissue compatible with invasion of the mesoappendix. Circumferential resection was compromised, suggesting the persistence of neoplasia in the patient even after the surgical approach, which would probably recommend the need for surgical approach. Therefore, the importance of sending collected materials for anatomopathological analysis is emphasized, since it helps in the clinical evaluation, in the etiological diagnosis, guides the medical conduct in the evolution of the case, as well as assisting in family mourning in cases of mortality.Keywords: Neuroendocrine tumor, Appendix, Histopathological analysis. |
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Neuroendocrine Neoplasm in Cecal Appendix: A Case ReportAlthough neuroendocrine neoplasms are relatively uncommon entities, the appendix is a site with relatively frequent emergence of this pathology and its precise diagnosis and clinical management have been a challenge for practitioners. This paper aims to present and discuss a case report of neuroendocrine neoplasia in the appendix of a patient with acute abdomen who underwent appendectomy. A 46-year-old man referred to the Emergency Department complaining of abdominal pain in the right iliac fossa and signs of peritoneal irritation. After diagnosis of acute appendicitis, the patient underwent appendectomy. In a macroscopic analysis, an area of 1.9 cm long, hardened, irregular and yellowish shapes was noted in the distal third of the appendix. Histopathological analysis showed neoplasia consisting of invasive islands of monotonous rounded epithelioid cells, large areas of necrosis, high mitotic activity, neural and angiolymphatic invasion and extension to adipose tissue compatible with invasion of the mesoappendix. Circumferential resection was compromised, suggesting the persistence of neoplasia in the patient even after the surgical approach, which would probably recommend the need for surgical approach. Therefore, the importance of sending collected materials for anatomopathological analysis is emphasized, since it helps in the clinical evaluation, in the etiological diagnosis, guides the medical conduct in the evolution of the case, as well as assisting in family mourning in cases of mortality.Keywords: Neuroendocrine tumor, Appendix, Histopathological analysis. Instituto Persona de Educação Superior2019-10-27info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://amadeusjournal.emnuvens.com.br/amadeus/article/view/8410.14295/aimj.v4i7.84Amadeus International Multidisciplinary Journal; Vol. 4 No. 7 (2019); 118-126Amadeus International Multidisciplinary Journal; v. 4 n. 7 (2019); 118-1262525-8281reponame:Amadeus International Multidisciplinary Journalinstname:Instituto Persona de Educação Superiorinstacron:IPESenghttps://amadeusjournal.emnuvens.com.br/amadeus/article/view/84/171Copyright (c) 2019 Amadeus International Multidisciplinary Journalinfo:eu-repo/semantics/openAccessFeitosa, Pedro Walisson GomesRodrigues, Andrezza LoboFelix, Esther Barbosa GonçalvesFreitas Neta, Maria Stella Batista deMachado, Sávio Samuel Feitosa2019-12-18T14:15:13Zoai:ojs.emnuvens.com.br:article/84Revistahttps://amadeusjournal.emnuvens.com.br/amadeus/indexPRIhttps://amadeusjournal.emnuvens.com.br/amadeus/oaiamadeusjournal@gmail.com2525-82812525-8281opendoar:2023-01-12T16:39:18.556599Amadeus International Multidisciplinary Journal - Instituto Persona de Educação Superiorfalse |
dc.title.none.fl_str_mv |
Neuroendocrine Neoplasm in Cecal Appendix: A Case Report |
title |
Neuroendocrine Neoplasm in Cecal Appendix: A Case Report |
spellingShingle |
Neuroendocrine Neoplasm in Cecal Appendix: A Case Report Feitosa, Pedro Walisson Gomes |
title_short |
Neuroendocrine Neoplasm in Cecal Appendix: A Case Report |
title_full |
Neuroendocrine Neoplasm in Cecal Appendix: A Case Report |
title_fullStr |
Neuroendocrine Neoplasm in Cecal Appendix: A Case Report |
title_full_unstemmed |
Neuroendocrine Neoplasm in Cecal Appendix: A Case Report |
title_sort |
Neuroendocrine Neoplasm in Cecal Appendix: A Case Report |
author |
Feitosa, Pedro Walisson Gomes |
author_facet |
Feitosa, Pedro Walisson Gomes Rodrigues, Andrezza Lobo Felix, Esther Barbosa Gonçalves Freitas Neta, Maria Stella Batista de Machado, Sávio Samuel Feitosa |
author_role |
author |
author2 |
Rodrigues, Andrezza Lobo Felix, Esther Barbosa Gonçalves Freitas Neta, Maria Stella Batista de Machado, Sávio Samuel Feitosa |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Feitosa, Pedro Walisson Gomes Rodrigues, Andrezza Lobo Felix, Esther Barbosa Gonçalves Freitas Neta, Maria Stella Batista de Machado, Sávio Samuel Feitosa |
description |
Although neuroendocrine neoplasms are relatively uncommon entities, the appendix is a site with relatively frequent emergence of this pathology and its precise diagnosis and clinical management have been a challenge for practitioners. This paper aims to present and discuss a case report of neuroendocrine neoplasia in the appendix of a patient with acute abdomen who underwent appendectomy. A 46-year-old man referred to the Emergency Department complaining of abdominal pain in the right iliac fossa and signs of peritoneal irritation. After diagnosis of acute appendicitis, the patient underwent appendectomy. In a macroscopic analysis, an area of 1.9 cm long, hardened, irregular and yellowish shapes was noted in the distal third of the appendix. Histopathological analysis showed neoplasia consisting of invasive islands of monotonous rounded epithelioid cells, large areas of necrosis, high mitotic activity, neural and angiolymphatic invasion and extension to adipose tissue compatible with invasion of the mesoappendix. Circumferential resection was compromised, suggesting the persistence of neoplasia in the patient even after the surgical approach, which would probably recommend the need for surgical approach. Therefore, the importance of sending collected materials for anatomopathological analysis is emphasized, since it helps in the clinical evaluation, in the etiological diagnosis, guides the medical conduct in the evolution of the case, as well as assisting in family mourning in cases of mortality.Keywords: Neuroendocrine tumor, Appendix, Histopathological analysis. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-10-27 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://amadeusjournal.emnuvens.com.br/amadeus/article/view/84 10.14295/aimj.v4i7.84 |
url |
https://amadeusjournal.emnuvens.com.br/amadeus/article/view/84 |
identifier_str_mv |
10.14295/aimj.v4i7.84 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://amadeusjournal.emnuvens.com.br/amadeus/article/view/84/171 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2019 Amadeus International Multidisciplinary Journal info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2019 Amadeus International Multidisciplinary Journal |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Instituto Persona de Educação Superior |
publisher.none.fl_str_mv |
Instituto Persona de Educação Superior |
dc.source.none.fl_str_mv |
Amadeus International Multidisciplinary Journal; Vol. 4 No. 7 (2019); 118-126 Amadeus International Multidisciplinary Journal; v. 4 n. 7 (2019); 118-126 2525-8281 reponame:Amadeus International Multidisciplinary Journal instname:Instituto Persona de Educação Superior instacron:IPES |
instname_str |
Instituto Persona de Educação Superior |
instacron_str |
IPES |
institution |
IPES |
reponame_str |
Amadeus International Multidisciplinary Journal |
collection |
Amadeus International Multidisciplinary Journal |
repository.name.fl_str_mv |
Amadeus International Multidisciplinary Journal - Instituto Persona de Educação Superior |
repository.mail.fl_str_mv |
amadeusjournal@gmail.com |
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1797051333845450752 |