Estimate of dietary intake of chloropropanols (3-MCPD and 1,3-DCP) and health risk assessment
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Data de Publicação: | 2013 |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório do Instituto de Tecnologia de Alimentos |
Texto Completo: | http://repositorio.ital.sp.gov.br/jspui/handle/123456789/468 |
Resumo: | Chloropropanols, including 3-monochloropropane-1,2-diol (3-MCPD) and 1,3-dichloropropan-2-ol (1,3-DCP), comprise a group of chemical contaminants with carcinogenic and genotoxic properties. They have been found in a variety of processed foods and food ingredients, such as hydrolyzed vegetable protein, soy sauce, cereal-based products, malt-derived ingredients, and smoked foods. This study aimed to assess the dietary exposure to 3-MCPD and 1,3-DCP in Brazil and verify whether the presence of these substances in foods could represent health risks. The intake was calculated by combining data on food consumption, provided by the Consumer Expenditure Survey 2008-2009, with the levels of contaminant occurrence determined by gas chromatography-mass spectrometry. The exposure to 3-MCPD ranged from 0.06 to 0.51 μg.kg bw–1.day–1 considering average and high consumers, while the intake of 1,3-DCP was estimated to be 0.0036 μg.kg bw–1.day–1 in the worst case scenario evaluated. Based on these results, it was verified that the Brazilians’ exposure to chloropropanols does not present a significant health risk. However, the consumption of specific foods containing high levels of 3-MCPD could exceed the provisional maximum tolerable daily intake of 2 μg.kg bw–1 established for this compound and, therefore, represent a potential concern. |
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Estimate of dietary intake of chloropropanols (3-MCPD and 1,3-DCP) and health risk assessmentContaminantsProcessed foodsMargin of exposure (MOE)Chloropropanols, including 3-monochloropropane-1,2-diol (3-MCPD) and 1,3-dichloropropan-2-ol (1,3-DCP), comprise a group of chemical contaminants with carcinogenic and genotoxic properties. They have been found in a variety of processed foods and food ingredients, such as hydrolyzed vegetable protein, soy sauce, cereal-based products, malt-derived ingredients, and smoked foods. This study aimed to assess the dietary exposure to 3-MCPD and 1,3-DCP in Brazil and verify whether the presence of these substances in foods could represent health risks. The intake was calculated by combining data on food consumption, provided by the Consumer Expenditure Survey 2008-2009, with the levels of contaminant occurrence determined by gas chromatography-mass spectrometry. The exposure to 3-MCPD ranged from 0.06 to 0.51 μg.kg bw–1.day–1 considering average and high consumers, while the intake of 1,3-DCP was estimated to be 0.0036 μg.kg bw–1.day–1 in the worst case scenario evaluated. Based on these results, it was verified that the Brazilians’ exposure to chloropropanols does not present a significant health risk. However, the consumption of specific foods containing high levels of 3-MCPD could exceed the provisional maximum tolerable daily intake of 2 μg.kg bw–1 established for this compound and, therefore, represent a potential concern.Arisseto, Adriana Pavesi; et al.2022-09-26T19:19:59Z2022-09-26T19:19:59Z2013info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfCiência Tecnologia de Alimentos, Campinas, v. 33, (Supl.1) , p. 125-133, fev. 2013.0101-2061http://repositorio.ital.sp.gov.br/jspui/handle/123456789/468reponame:Repositório do Instituto de Tecnologia de Alimentosinstname:Instituto de Tecnologia de Alimentos (ITAL)instacron:ITALenginfo:eu-repo/semantics/openAccess2022-09-26T19:19:59Zoai:http://repositorio.ital.sp.gov.br:123456789/468Repositório InstitucionalPUBhttp://repositorio.ital.sp.gov.br/oai/requestbjftsec@ital.sp.gov.br || bjftsec@ital.sp.gov.bropendoar:2022-09-26T19:19:59Repositório do Instituto de Tecnologia de Alimentos - Instituto de Tecnologia de Alimentos (ITAL)false |
dc.title.none.fl_str_mv |
Estimate of dietary intake of chloropropanols (3-MCPD and 1,3-DCP) and health risk assessment |
title |
Estimate of dietary intake of chloropropanols (3-MCPD and 1,3-DCP) and health risk assessment |
spellingShingle |
Estimate of dietary intake of chloropropanols (3-MCPD and 1,3-DCP) and health risk assessment Arisseto, Adriana Pavesi; et al. Contaminants Processed foods Margin of exposure (MOE) |
title_short |
Estimate of dietary intake of chloropropanols (3-MCPD and 1,3-DCP) and health risk assessment |
title_full |
Estimate of dietary intake of chloropropanols (3-MCPD and 1,3-DCP) and health risk assessment |
title_fullStr |
Estimate of dietary intake of chloropropanols (3-MCPD and 1,3-DCP) and health risk assessment |
title_full_unstemmed |
Estimate of dietary intake of chloropropanols (3-MCPD and 1,3-DCP) and health risk assessment |
title_sort |
Estimate of dietary intake of chloropropanols (3-MCPD and 1,3-DCP) and health risk assessment |
author |
Arisseto, Adriana Pavesi; et al. |
author_facet |
Arisseto, Adriana Pavesi; et al. |
author_role |
author |
dc.contributor.none.fl_str_mv |
|
dc.contributor.author.fl_str_mv |
Arisseto, Adriana Pavesi; et al. |
dc.subject.none.fl_str_mv |
|
dc.subject.por.fl_str_mv |
Contaminants Processed foods Margin of exposure (MOE) |
topic |
Contaminants Processed foods Margin of exposure (MOE) |
description |
Chloropropanols, including 3-monochloropropane-1,2-diol (3-MCPD) and 1,3-dichloropropan-2-ol (1,3-DCP), comprise a group of chemical contaminants with carcinogenic and genotoxic properties. They have been found in a variety of processed foods and food ingredients, such as hydrolyzed vegetable protein, soy sauce, cereal-based products, malt-derived ingredients, and smoked foods. This study aimed to assess the dietary exposure to 3-MCPD and 1,3-DCP in Brazil and verify whether the presence of these substances in foods could represent health risks. The intake was calculated by combining data on food consumption, provided by the Consumer Expenditure Survey 2008-2009, with the levels of contaminant occurrence determined by gas chromatography-mass spectrometry. The exposure to 3-MCPD ranged from 0.06 to 0.51 μg.kg bw–1.day–1 considering average and high consumers, while the intake of 1,3-DCP was estimated to be 0.0036 μg.kg bw–1.day–1 in the worst case scenario evaluated. Based on these results, it was verified that the Brazilians’ exposure to chloropropanols does not present a significant health risk. However, the consumption of specific foods containing high levels of 3-MCPD could exceed the provisional maximum tolerable daily intake of 2 μg.kg bw–1 established for this compound and, therefore, represent a potential concern. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013 2022-09-26T19:19:59Z 2022-09-26T19:19:59Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
|
dc.identifier.uri.fl_str_mv |
Ciência Tecnologia de Alimentos, Campinas, v. 33, (Supl.1) , p. 125-133, fev. 2013. 0101-2061 http://repositorio.ital.sp.gov.br/jspui/handle/123456789/468 |
identifier_str_mv |
Ciência Tecnologia de Alimentos, Campinas, v. 33, (Supl.1) , p. 125-133, fev. 2013. 0101-2061 |
url |
http://repositorio.ital.sp.gov.br/jspui/handle/123456789/468 |
dc.language.none.fl_str_mv |
|
dc.language.iso.fl_str_mv |
eng |
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language |
eng |
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info:eu-repo/semantics/openAccess |
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eu_rights_str_mv |
openAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
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reponame:Repositório do Instituto de Tecnologia de Alimentos instname:Instituto de Tecnologia de Alimentos (ITAL) instacron:ITAL |
instname_str |
Instituto de Tecnologia de Alimentos (ITAL) |
instacron_str |
ITAL |
institution |
ITAL |
reponame_str |
Repositório do Instituto de Tecnologia de Alimentos |
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Repositório do Instituto de Tecnologia de Alimentos |
repository.name.fl_str_mv |
Repositório do Instituto de Tecnologia de Alimentos - Instituto de Tecnologia de Alimentos (ITAL) |
repository.mail.fl_str_mv |
bjftsec@ital.sp.gov.br || bjftsec@ital.sp.gov.br |
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