Prevention and monitoring of anthracycline-induced cardiotoxicity in breast cancer patients

Detalhes bibliográficos
Autor(a) principal: Bastos, Paloma Bianca Veras
Data de Publicação: 2022
Outros Autores: Fortes, Renata Costa, Mesquita, Elciane Falcão de
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista JRG de Estudos Acadêmicos
Texto Completo: http://revistajrg.com/index.php/jrg/article/view/399
Resumo: Introduction: Anthracyclines are the most effective chemotherapy drugs for the treatment of breast cancer, but they have cardiotoxic effects. Objective: To investigate methods used to monitor and prevent cardiotoxicity caused by anthracyclines in breast cancer patients. Methods: Integrative literature review carried out through searches in the Biblioteca Virtual de Saúde (BVS). Results: It is recommended to check left ventricular ejection fraction every three months and arterial stiffness until the end of treatment. Ramipril obtained cardioprotective effects during the use of anthracyclines. Lisinopril associated with bisoprolol had good cardioprotective results. The use of statins during treatment reduced hospitalization rates for heart failure. Platycondon grandiplorum prevented cardiotoxicity. As an alternative for replacing common anthracyclines, liposomal anthracyclines are used. Conclusion: There is a need to increase the production of studies on the drugs and monitoring methods that were analyzed.
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spelling Prevention and monitoring of anthracycline-induced cardiotoxicity in breast cancer patientsPrevenção e monitoramento da cardiotoxicidade induzida por antraciclinas em pacientes com câncer de mamaantraciclinascâncer de mamacardiotoxicidadeprevençãoIntroduction: Anthracyclines are the most effective chemotherapy drugs for the treatment of breast cancer, but they have cardiotoxic effects. Objective: To investigate methods used to monitor and prevent cardiotoxicity caused by anthracyclines in breast cancer patients. Methods: Integrative literature review carried out through searches in the Biblioteca Virtual de Saúde (BVS). Results: It is recommended to check left ventricular ejection fraction every three months and arterial stiffness until the end of treatment. Ramipril obtained cardioprotective effects during the use of anthracyclines. Lisinopril associated with bisoprolol had good cardioprotective results. The use of statins during treatment reduced hospitalization rates for heart failure. Platycondon grandiplorum prevented cardiotoxicity. As an alternative for replacing common anthracyclines, liposomal anthracyclines are used. Conclusion: There is a need to increase the production of studies on the drugs and monitoring methods that were analyzed.Introdução: Os antracíclicos são os quimioterápicos mais efetivos para o tratamento do câncer de mama, mas eles possuem efeitos cardiotóxicos. Objetivo: Investigar métodos utilizados para monitorar e prevenir a cardiotoxicidade causada pelas antraciclinas em pacientes com câncer de mama. Métodos: Revisão integrativa da literatura realizada por meio de buscas na Biblioteca Virtual de Saúde (BVS). Resultados:  Recomenda-se verificar a fração de ejeção do ventrículo esquerdo a cada três meses e a rigidez arterial até o fim do tratamento. O ramipril obteve efeitos cardioprotetores durante o uso de antraciclinas. O lisinopril associado ao bisoprolol obteve bons resultados cardioprotetores. O uso de estatinas durante o tratamento reduziu taxas de internações por insuficiência cardíaca. A Platycondon grandiplorum preveniu a cardiotoxicidade. Como alternativa para substituição de antracíclicos comuns, utiliza-se antraciclinas lipossomais. Conclusão: Há necessidade do aumento da produção de estudos acerca dos medicamentos e métodos de monitorização que foram analisados. Palavras-chave: antraciclinas, câncer de mama, cardiotoxicidade, prevenção.Editora JRG2022-11-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigo avaliado pelos Paresapplication/pdfhttp://revistajrg.com/index.php/jrg/article/view/39910.5281/zenodo.7308173ark:/57118/JRG.v5i11.399JRG Journal of Academic Studies; Vol. 5 No. 11 (2022): Revista JRG de Estudos Acadêmicos; 240-250JRG Journal of Academic Studies ; Vol. 5 Núm. 11 (2022): Revista JRG de Estudos Acadêmicos; 240-250JRG Journal of Academic Studies; V. 5 N. 11 (2022): Revista JRG de Estudos Acadêmicos; 240-250Revista JRG de Estudos Acadêmicos ; v. 5 n. 11 (2022): Revista JRG de Estudos Acadêmicos; 240-2502595-1661reponame:Revista JRG de Estudos Acadêmicosinstname:Editora JRGinstacron:JRGporhttp://revistajrg.com/index.php/jrg/article/view/399/489ark:/57118/jrg.v5i11.399.g489https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccess Bastos, Paloma Bianca VerasFortes, Renata Costa Mesquita, Elciane Falcão de2022-10-11T20:17:46Zoai:ojs2.revistajrg.com:article/399Revistahttp://revistajrg.com/index.php/jrgPRIhttp://revistajrg.com/index.php/jrg/oaiprofessorjonas@gmail.com||2595-16612595-1661opendoar:2022-10-11T20:17:46Revista JRG de Estudos Acadêmicos - Editora JRGfalse
dc.title.none.fl_str_mv Prevention and monitoring of anthracycline-induced cardiotoxicity in breast cancer patients
Prevenção e monitoramento da cardiotoxicidade induzida por antraciclinas em pacientes com câncer de mama
title Prevention and monitoring of anthracycline-induced cardiotoxicity in breast cancer patients
spellingShingle Prevention and monitoring of anthracycline-induced cardiotoxicity in breast cancer patients
Bastos, Paloma Bianca Veras
antraciclinas
câncer de mama
cardiotoxicidade
prevenção
title_short Prevention and monitoring of anthracycline-induced cardiotoxicity in breast cancer patients
title_full Prevention and monitoring of anthracycline-induced cardiotoxicity in breast cancer patients
title_fullStr Prevention and monitoring of anthracycline-induced cardiotoxicity in breast cancer patients
title_full_unstemmed Prevention and monitoring of anthracycline-induced cardiotoxicity in breast cancer patients
title_sort Prevention and monitoring of anthracycline-induced cardiotoxicity in breast cancer patients
author Bastos, Paloma Bianca Veras
author_facet Bastos, Paloma Bianca Veras
Fortes, Renata Costa
Mesquita, Elciane Falcão de
author_role author
author2 Fortes, Renata Costa
Mesquita, Elciane Falcão de
author2_role author
author
dc.contributor.author.fl_str_mv Bastos, Paloma Bianca Veras
Fortes, Renata Costa
Mesquita, Elciane Falcão de
dc.subject.por.fl_str_mv antraciclinas
câncer de mama
cardiotoxicidade
prevenção
topic antraciclinas
câncer de mama
cardiotoxicidade
prevenção
description Introduction: Anthracyclines are the most effective chemotherapy drugs for the treatment of breast cancer, but they have cardiotoxic effects. Objective: To investigate methods used to monitor and prevent cardiotoxicity caused by anthracyclines in breast cancer patients. Methods: Integrative literature review carried out through searches in the Biblioteca Virtual de Saúde (BVS). Results: It is recommended to check left ventricular ejection fraction every three months and arterial stiffness until the end of treatment. Ramipril obtained cardioprotective effects during the use of anthracyclines. Lisinopril associated with bisoprolol had good cardioprotective results. The use of statins during treatment reduced hospitalization rates for heart failure. Platycondon grandiplorum prevented cardiotoxicity. As an alternative for replacing common anthracyclines, liposomal anthracyclines are used. Conclusion: There is a need to increase the production of studies on the drugs and monitoring methods that were analyzed.
publishDate 2022
dc.date.none.fl_str_mv 2022-11-09
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Artigo avaliado pelos Pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://revistajrg.com/index.php/jrg/article/view/399
10.5281/zenodo.7308173
ark:/57118/JRG.v5i11.399
url http://revistajrg.com/index.php/jrg/article/view/399
identifier_str_mv 10.5281/zenodo.7308173
ark:/57118/JRG.v5i11.399
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv http://revistajrg.com/index.php/jrg/article/view/399/489
ark:/57118/jrg.v5i11.399.g489
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info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Editora JRG
publisher.none.fl_str_mv Editora JRG
dc.source.none.fl_str_mv JRG Journal of Academic Studies; Vol. 5 No. 11 (2022): Revista JRG de Estudos Acadêmicos; 240-250
JRG Journal of Academic Studies ; Vol. 5 Núm. 11 (2022): Revista JRG de Estudos Acadêmicos; 240-250
JRG Journal of Academic Studies; V. 5 N. 11 (2022): Revista JRG de Estudos Acadêmicos; 240-250
Revista JRG de Estudos Acadêmicos ; v. 5 n. 11 (2022): Revista JRG de Estudos Acadêmicos; 240-250
2595-1661
reponame:Revista JRG de Estudos Acadêmicos
instname:Editora JRG
instacron:JRG
instname_str Editora JRG
instacron_str JRG
institution JRG
reponame_str Revista JRG de Estudos Acadêmicos
collection Revista JRG de Estudos Acadêmicos
repository.name.fl_str_mv Revista JRG de Estudos Acadêmicos - Editora JRG
repository.mail.fl_str_mv professorjonas@gmail.com||
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