An??lise da variabilidade da frequ??ncia card??aca em pacientes bronquiect??sicos est??veis
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Biblioteca Digital de Teses e Dissertações da Uninove |
Texto Completo: | http://bibliotecatede.uninove.br/tede/handle/tede/887 |
Resumo: | Introduction: Bronchiectasis (BCQ) is a chronic and debilitating respiratory disease with extrapulmonary factors that suggest the presence of cardiovascular autonomic dysfunction, however, based in our knowledge, there are no studies assessing autonomic function of these patients. Objectives: To assess the autonomic function in patients with clinically stable BCQ and correlate them with pulmonary function indices, functional and aerobic capacity. Method: Parameters of cardiac autonomic regulation were studied, by heart rate variability (HRV) in 26 patients with BCQ, being compared with healthy individuals and contrasted with rates of lung, functional and physical capacity rates, respectively by spirometry, incremental shuttle walking test (ISWT) and maximal cardiopulmonary exercise test (CPET). Results: The patients showed significant reduction in the high frequency component (HF, n.u.) (38 ?? 14 vs 53 ?? 15, p= 0.02) and increased in low frequency (LF, n.u.) (61 ?? 13 vs 47 ?? 15, p= 0.02) and in the relationship between the two components (LF/HF) (p=0.02) compared to healthy. There was no correlation between HRV indices with functional and physical capacity. The component of HF was positively correlated with forced expiratory volume in first second (FEV1) and the ratio FEV1 / forced vital capacity (FVC) (r = 0.4 for both). While there was a negative and significant correlation between LF and LF / HF with FEV1 (r = 0.4 and 0.3 respectively) and the FEV1/FVC (r = 0.5 and 0.4 respectively). Conclusion: BCQ patients have worse cardiac autonomic regulation in relation to healthy subjects, and the reduction in lung function is correlated to autonomic dysfunction in these patients with increased activation of the sympathetic nervous system. |
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Dal Corso, SimoneCPF:00000000000http://lattes.cnpq.br/9690847988531306Chiavegato, Luciana Diashttp://lattes.cnpq.br/6275262557452273Sampaio, Luciana Maria Malos??http://lattes.cnpq.br/2970138065407046CPF:36566947884http://lattes.cnpq.br/1970898295337775Amaral, Tatiane Soares2015-04-22T17:20:41Z2014-11-282013-12-17AMARAL, Tatiane Soares. An??lise da variabilidade da frequ??ncia card??aca em pacientes bronquiect??sicos est??veis. 2013. 55 f. Disserta????o (Mestrado em Sa??de) - Universidade Nove de Julho, S??o Paulo, 2013.http://bibliotecatede.uninove.br/tede/handle/tede/887Introduction: Bronchiectasis (BCQ) is a chronic and debilitating respiratory disease with extrapulmonary factors that suggest the presence of cardiovascular autonomic dysfunction, however, based in our knowledge, there are no studies assessing autonomic function of these patients. Objectives: To assess the autonomic function in patients with clinically stable BCQ and correlate them with pulmonary function indices, functional and aerobic capacity. Method: Parameters of cardiac autonomic regulation were studied, by heart rate variability (HRV) in 26 patients with BCQ, being compared with healthy individuals and contrasted with rates of lung, functional and physical capacity rates, respectively by spirometry, incremental shuttle walking test (ISWT) and maximal cardiopulmonary exercise test (CPET). Results: The patients showed significant reduction in the high frequency component (HF, n.u.) (38 ?? 14 vs 53 ?? 15, p= 0.02) and increased in low frequency (LF, n.u.) (61 ?? 13 vs 47 ?? 15, p= 0.02) and in the relationship between the two components (LF/HF) (p=0.02) compared to healthy. There was no correlation between HRV indices with functional and physical capacity. The component of HF was positively correlated with forced expiratory volume in first second (FEV1) and the ratio FEV1 / forced vital capacity (FVC) (r = 0.4 for both). While there was a negative and significant correlation between LF and LF / HF with FEV1 (r = 0.4 and 0.3 respectively) and the FEV1/FVC (r = 0.5 and 0.4 respectively). Conclusion: BCQ patients have worse cardiac autonomic regulation in relation to healthy subjects, and the reduction in lung function is correlated to autonomic dysfunction in these patients with increased activation of the sympathetic nervous system.Introdu????o: A bronquiectasia (BCQ) ?? uma doen??a respirat??ria cr??nica e debilitante com fatores extrapulmonares que sugerem presen??a de disfun????o auton??mica cardiovascular, no entanto, que seja de nosso conhecimento, n??o h?? estudos que avaliaram a fun????o auton??mica desses indiv??duos. Objetivo: Avaliar a fun????o auton??mica de pacientes com BCQ clinicamente est??veis e correlacion??-las com ??ndices de fun????o pulmonar, capacidade funcional e aer??bia. M??todo: Foram estudados par??metros de regula????o auton??mica card??aca, pela variabilidade da frequ??ncia card??aca (VFC) de 26 pacientes com diagn??stico de BCQ, sendo comparados com indiv??duos saud??veis e contrastados com ??ndices de capacidade pulmonar, funcional e f??sica, respectivamente pela espirometria, shuttle walking teste incremental (SWTI) e teste de exerc??cio cardiopulmonar m??ximo (TECP). Resultados: Os pacientes apresentaram redu????o significante do componente de alta frequ??ncia (AF, u.n.) (38 ?? 14 vs 53 ?? 15, p= 0,02) e aumento do de baixa frequ??ncia (BF, u.n.) (61 ?? 13 vs 47 ?? 15, p= 0,02) e da rela????o entre os dois componentes (BF/AF) (p=0,02) em rela????o aos saud??veis. N??o houve correla????o da VFC com ??ndices de capacidade funcional e f??sica. O componente de AF se correlacionou positivamente com o volume expirat??rio for??ado no primeiro segundo (VEF1) e com a rela????o VEF1/capacidade vital for??ada (CVF) (r = 0,4 em ambos; p = 0,02 e p=0,01, respectivamente). Enquanto que houve correla????o negativa e significante do BF e da rela????o BF/AF com o VEF1 (r= - 0,4, p= 0,01 e r= 0,3, p= 0,05 respectivamente) e com o VEF1/CVF (r= 0,5, p= 0,01 e r= 0,4, p= 0,01 respectivamente). Conclus??o: Pacientes com BCQ apresentam pior regula????o auton??mica card??aca em rela????o aos indiv??duos saud??veis, sendo que a redu????o da fun????o pulmonar est?? relacionada ?? disautonomia nestes pacientes com maior ativa????o do sistema nervoso simp??tico.Made available in DSpace on 2015-04-22T17:20:41Z (GMT). No. of bitstreams: 1 Tatiane S Amaral.pdf: 830160 bytes, checksum: 8cfbec933f5c24f3ed10d31d4037cb98 (MD5) Previous issue date: 2013-12-17application/pdfporUniversidade Nove de JulhoPrograma de P??s-Gradua????o em Ci??ncias da Reabilita????oUNINOVEBRSa??debronquiectasiaexerc??cioavalia????osistema nervoso aut??nomobronchiectasisexerciseevaluationautonomic nervous systemCIENCIAS DA SAUDEAn??lise da variabilidade da frequ??ncia card??aca em pacientes bronquiect??sicos est??veisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis8765449414823306929600info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da Uninoveinstname:Universidade Nove de Julho (UNINOVE)instacron:UNINOVEORIGINALTatiane S Amaral.pdfapplication/pdf830160http://localhost:8080/tede/bitstream/tede/887/1/Tatiane+S+Amaral.pdf8cfbec933f5c24f3ed10d31d4037cb98MD51tede/8872018-06-15 12:45:34.67oai:localhost:tede/887Biblioteca Digital de Teses e Dissertaçõeshttp://bibliotecatede.uninove.br/PRIhttp://bibliotecatede.uninove.br/oai/requestbibliotecatede@uninove.br||bibliotecatede@uninove.bropendoar:2018-06-15T15:45:34Biblioteca Digital de Teses e Dissertações da Uninove - Universidade Nove de Julho (UNINOVE)false |
dc.title.por.fl_str_mv |
An??lise da variabilidade da frequ??ncia card??aca em pacientes bronquiect??sicos est??veis |
title |
An??lise da variabilidade da frequ??ncia card??aca em pacientes bronquiect??sicos est??veis |
spellingShingle |
An??lise da variabilidade da frequ??ncia card??aca em pacientes bronquiect??sicos est??veis Amaral, Tatiane Soares bronquiectasia exerc??cio avalia????o sistema nervoso aut??nomo bronchiectasis exercise evaluation autonomic nervous system CIENCIAS DA SAUDE |
title_short |
An??lise da variabilidade da frequ??ncia card??aca em pacientes bronquiect??sicos est??veis |
title_full |
An??lise da variabilidade da frequ??ncia card??aca em pacientes bronquiect??sicos est??veis |
title_fullStr |
An??lise da variabilidade da frequ??ncia card??aca em pacientes bronquiect??sicos est??veis |
title_full_unstemmed |
An??lise da variabilidade da frequ??ncia card??aca em pacientes bronquiect??sicos est??veis |
title_sort |
An??lise da variabilidade da frequ??ncia card??aca em pacientes bronquiect??sicos est??veis |
author |
Amaral, Tatiane Soares |
author_facet |
Amaral, Tatiane Soares |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Dal Corso, Simone |
dc.contributor.advisor1ID.fl_str_mv |
CPF:00000000000 |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/9690847988531306 |
dc.contributor.referee1.fl_str_mv |
Chiavegato, Luciana Dias |
dc.contributor.referee1Lattes.fl_str_mv |
http://lattes.cnpq.br/6275262557452273 |
dc.contributor.referee2.fl_str_mv |
Sampaio, Luciana Maria Malos?? |
dc.contributor.referee2Lattes.fl_str_mv |
http://lattes.cnpq.br/2970138065407046 |
dc.contributor.authorID.fl_str_mv |
CPF:36566947884 |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/1970898295337775 |
dc.contributor.author.fl_str_mv |
Amaral, Tatiane Soares |
contributor_str_mv |
Dal Corso, Simone Chiavegato, Luciana Dias Sampaio, Luciana Maria Malos?? |
dc.subject.por.fl_str_mv |
bronquiectasia exerc??cio avalia????o sistema nervoso aut??nomo |
topic |
bronquiectasia exerc??cio avalia????o sistema nervoso aut??nomo bronchiectasis exercise evaluation autonomic nervous system CIENCIAS DA SAUDE |
dc.subject.eng.fl_str_mv |
bronchiectasis exercise evaluation autonomic nervous system |
dc.subject.cnpq.fl_str_mv |
CIENCIAS DA SAUDE |
description |
Introduction: Bronchiectasis (BCQ) is a chronic and debilitating respiratory disease with extrapulmonary factors that suggest the presence of cardiovascular autonomic dysfunction, however, based in our knowledge, there are no studies assessing autonomic function of these patients. Objectives: To assess the autonomic function in patients with clinically stable BCQ and correlate them with pulmonary function indices, functional and aerobic capacity. Method: Parameters of cardiac autonomic regulation were studied, by heart rate variability (HRV) in 26 patients with BCQ, being compared with healthy individuals and contrasted with rates of lung, functional and physical capacity rates, respectively by spirometry, incremental shuttle walking test (ISWT) and maximal cardiopulmonary exercise test (CPET). Results: The patients showed significant reduction in the high frequency component (HF, n.u.) (38 ?? 14 vs 53 ?? 15, p= 0.02) and increased in low frequency (LF, n.u.) (61 ?? 13 vs 47 ?? 15, p= 0.02) and in the relationship between the two components (LF/HF) (p=0.02) compared to healthy. There was no correlation between HRV indices with functional and physical capacity. The component of HF was positively correlated with forced expiratory volume in first second (FEV1) and the ratio FEV1 / forced vital capacity (FVC) (r = 0.4 for both). While there was a negative and significant correlation between LF and LF / HF with FEV1 (r = 0.4 and 0.3 respectively) and the FEV1/FVC (r = 0.5 and 0.4 respectively). Conclusion: BCQ patients have worse cardiac autonomic regulation in relation to healthy subjects, and the reduction in lung function is correlated to autonomic dysfunction in these patients with increased activation of the sympathetic nervous system. |
publishDate |
2013 |
dc.date.issued.fl_str_mv |
2013-12-17 |
dc.date.available.fl_str_mv |
2014-11-28 |
dc.date.accessioned.fl_str_mv |
2015-04-22T17:20:41Z |
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info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
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masterThesis |
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publishedVersion |
dc.identifier.citation.fl_str_mv |
AMARAL, Tatiane Soares. An??lise da variabilidade da frequ??ncia card??aca em pacientes bronquiect??sicos est??veis. 2013. 55 f. Disserta????o (Mestrado em Sa??de) - Universidade Nove de Julho, S??o Paulo, 2013. |
dc.identifier.uri.fl_str_mv |
http://bibliotecatede.uninove.br/tede/handle/tede/887 |
identifier_str_mv |
AMARAL, Tatiane Soares. An??lise da variabilidade da frequ??ncia card??aca em pacientes bronquiect??sicos est??veis. 2013. 55 f. Disserta????o (Mestrado em Sa??de) - Universidade Nove de Julho, S??o Paulo, 2013. |
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UNINOVE |
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