Changes in the suprachiasmatic nucleus during aging: implications for biological rhythms
Autor(a) principal: | |
---|---|
Data de Publicação: | 2013 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Psychology & Neuroscience (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1983-32882013000300007 |
Resumo: | Animals have neural structures that allow them to anticipate environmental changes and then regulate physiological and behavioral functions in response to these alterations. The suprachiasmatic nucleus of the hypothalamus (SCN) is the main circadian pacemaker in many mammalian species. This structure synchronizes the biological rhythm based on photic information that is transmitted to the SCN through the retinohypothalamic tract. The aging process changes the structural complexity of the nervous system, from individual nerve cells to global changes, including the atrophy of total gray matter. Aged animals show internal time disruptions caused by morphological and neurochemical changes in SCN components. The effects of aging on circadian rhythm range from effects on simple physiological functions to effects on complex cognitive performance, including many psychiatric disorders that influence the well-being of the elderly. In this review, we summarize the effects of aging on morphological, neurochemical, and circadian rhythmic functions coordinated by the main circadian pacemaker, the SCN. |
id |
PUCRJ-1_f456a3199e63a5a4b5c411519a89e538 |
---|---|
oai_identifier_str |
oai:scielo:S1983-32882013000300007 |
network_acronym_str |
PUCRJ-1 |
network_name_str |
Psychology & Neuroscience (Online) |
repository_id_str |
|
spelling |
Changes in the suprachiasmatic nucleus during aging: implications for biological rhythmssuprachiasmatic nucleusagingmorphological and neurochemical changescircadian rhythmsAnimals have neural structures that allow them to anticipate environmental changes and then regulate physiological and behavioral functions in response to these alterations. The suprachiasmatic nucleus of the hypothalamus (SCN) is the main circadian pacemaker in many mammalian species. This structure synchronizes the biological rhythm based on photic information that is transmitted to the SCN through the retinohypothalamic tract. The aging process changes the structural complexity of the nervous system, from individual nerve cells to global changes, including the atrophy of total gray matter. Aged animals show internal time disruptions caused by morphological and neurochemical changes in SCN components. The effects of aging on circadian rhythm range from effects on simple physiological functions to effects on complex cognitive performance, including many psychiatric disorders that influence the well-being of the elderly. In this review, we summarize the effects of aging on morphological, neurochemical, and circadian rhythmic functions coordinated by the main circadian pacemaker, the SCN.Pontificia Universidade Católica do Rio de JaneiroUniversidade de BrasíliaUniversidade de São Paulo2013-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1983-32882013000300007Psychology & Neuroscience v.6 n.3 2013reponame:Psychology & Neuroscience (Online)instname:Instituto Brasileiro de Neuropsicologia e Comportamento (IBNeC)instacron:PUCRJ10.3922/j.psns.2013.3.07info:eu-repo/semantics/openAccessEngelberth,Rovena C. G. J.Pontes,André L. Bezerra deFiuza,Felipe PortoSilva,Kayo D. de AzevedoResende,Nayra da S.Azevedo,Carolina Virgínia de M.Costa,Miriam S. M. O.Cavalcante,Judney C.Nascimento Jr.,Expedito S.Gavioli,Elaine CristinaCavalcante,Jeferson S.eng2014-02-28T00:00:00Zoai:scielo:S1983-32882013000300007Revistahttps://www.apa.org/pubs/journals/pnePRIhttps://old.scielo.br/oai/scielo-oai.phppsycneuro@psycneuro.org1983-32881984-3054opendoar:2014-02-28T00:00Psychology & Neuroscience (Online) - Instituto Brasileiro de Neuropsicologia e Comportamento (IBNeC)false |
dc.title.none.fl_str_mv |
Changes in the suprachiasmatic nucleus during aging: implications for biological rhythms |
title |
Changes in the suprachiasmatic nucleus during aging: implications for biological rhythms |
spellingShingle |
Changes in the suprachiasmatic nucleus during aging: implications for biological rhythms Engelberth,Rovena C. G. J. suprachiasmatic nucleus aging morphological and neurochemical changes circadian rhythms |
title_short |
Changes in the suprachiasmatic nucleus during aging: implications for biological rhythms |
title_full |
Changes in the suprachiasmatic nucleus during aging: implications for biological rhythms |
title_fullStr |
Changes in the suprachiasmatic nucleus during aging: implications for biological rhythms |
title_full_unstemmed |
Changes in the suprachiasmatic nucleus during aging: implications for biological rhythms |
title_sort |
Changes in the suprachiasmatic nucleus during aging: implications for biological rhythms |
author |
Engelberth,Rovena C. G. J. |
author_facet |
Engelberth,Rovena C. G. J. Pontes,André L. Bezerra de Fiuza,Felipe Porto Silva,Kayo D. de Azevedo Resende,Nayra da S. Azevedo,Carolina Virgínia de M. Costa,Miriam S. M. O. Cavalcante,Judney C. Nascimento Jr.,Expedito S. Gavioli,Elaine Cristina Cavalcante,Jeferson S. |
author_role |
author |
author2 |
Pontes,André L. Bezerra de Fiuza,Felipe Porto Silva,Kayo D. de Azevedo Resende,Nayra da S. Azevedo,Carolina Virgínia de M. Costa,Miriam S. M. O. Cavalcante,Judney C. Nascimento Jr.,Expedito S. Gavioli,Elaine Cristina Cavalcante,Jeferson S. |
author2_role |
author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Engelberth,Rovena C. G. J. Pontes,André L. Bezerra de Fiuza,Felipe Porto Silva,Kayo D. de Azevedo Resende,Nayra da S. Azevedo,Carolina Virgínia de M. Costa,Miriam S. M. O. Cavalcante,Judney C. Nascimento Jr.,Expedito S. Gavioli,Elaine Cristina Cavalcante,Jeferson S. |
dc.subject.por.fl_str_mv |
suprachiasmatic nucleus aging morphological and neurochemical changes circadian rhythms |
topic |
suprachiasmatic nucleus aging morphological and neurochemical changes circadian rhythms |
description |
Animals have neural structures that allow them to anticipate environmental changes and then regulate physiological and behavioral functions in response to these alterations. The suprachiasmatic nucleus of the hypothalamus (SCN) is the main circadian pacemaker in many mammalian species. This structure synchronizes the biological rhythm based on photic information that is transmitted to the SCN through the retinohypothalamic tract. The aging process changes the structural complexity of the nervous system, from individual nerve cells to global changes, including the atrophy of total gray matter. Aged animals show internal time disruptions caused by morphological and neurochemical changes in SCN components. The effects of aging on circadian rhythm range from effects on simple physiological functions to effects on complex cognitive performance, including many psychiatric disorders that influence the well-being of the elderly. In this review, we summarize the effects of aging on morphological, neurochemical, and circadian rhythmic functions coordinated by the main circadian pacemaker, the SCN. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1983-32882013000300007 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1983-32882013000300007 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.3922/j.psns.2013.3.07 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Pontificia Universidade Católica do Rio de Janeiro Universidade de Brasília Universidade de São Paulo |
publisher.none.fl_str_mv |
Pontificia Universidade Católica do Rio de Janeiro Universidade de Brasília Universidade de São Paulo |
dc.source.none.fl_str_mv |
Psychology & Neuroscience v.6 n.3 2013 reponame:Psychology & Neuroscience (Online) instname:Instituto Brasileiro de Neuropsicologia e Comportamento (IBNeC) instacron:PUCRJ |
instname_str |
Instituto Brasileiro de Neuropsicologia e Comportamento (IBNeC) |
instacron_str |
PUCRJ |
institution |
PUCRJ |
reponame_str |
Psychology & Neuroscience (Online) |
collection |
Psychology & Neuroscience (Online) |
repository.name.fl_str_mv |
Psychology & Neuroscience (Online) - Instituto Brasileiro de Neuropsicologia e Comportamento (IBNeC) |
repository.mail.fl_str_mv |
psycneuro@psycneuro.org |
_version_ |
1754821072920772608 |