Detecção de lesões periapicais incipientes por subtração radiográfica com imagens panorâmicas digitais e digitalizadas

Detalhes bibliográficos
Autor(a) principal: Miguens Júnior, Sergio Augusto Quevedo
Data de Publicação: 2008
Tipo de documento: Tese
Idioma: por
Título da fonte: Repositório Institucional PUCRS
Texto Completo: http://hdl.handle.net/10923/398
Resumo: This thesis comprises two articles. In the first article, we assessed in vitro the ability of digital subtraction radiography (DSR) in the detection of incipient periapical lesions using panoramic digital and digitized radiographs. Periapical defects were created in dried human mandibles through application of 70% perchloric acid at times 2, 4, and 6 hours. Conventional and digital radiographs were obtained twice at time zero, with the aim of evaluating reproducibility of this technique, and sequentially before each application of the acid solution. Conventional radiographs were digitized using a scanner with the same attributes than direct digital radiographs: 150-dpi resolution, 8-bit mode and stored as non-compressed TIFF format. The software Adobe Photoshop® was used for DSR of the images in the following sequence: T0x0 repeated; T0xT2; T0xT4; and T0xT6. The variable under analysis was the difference between pixel intensity in control and test areas. Using ANOVA to compare the size of the areas marked to obtain pixel intensity values in different experimental times, no differences were observed between times both for the test (F= 0. 44; P = 0. 726) and for the control area (F= 1. 20; P = 0. 310). Comparing experimental times, there were significant differences, time 6 having the highest mean of mineral loss. Times 2 and 4 had no differences, but were significantly higher than time 0, both for digitized (F= 45. 01; P< 0. 001) and for digital images (F= 30. 80; P < 0. 001). We concluded that DSR of panoramic radiographic images, whether digital or digitized, allows for detection of incipient periapical defects. In the second article, we compared in vitro specificity, sensitivity, and diagnostic accuracy of digital subtraction radiography (DSR) in digital and digitized panoramic images in the detection of incipient periapical lesions. The images were assessed by an experienced and blinded observer, who attributed scores 0 (absence of image representing mineral loss) or 1 (presence of dark image representing mineral loss) to each image. Results were evaluated using analysis of variance (ANOVA), complemented by Dunnett’s T3 multiple comparison test; the level of significance was set at 5%. The observer showed Kappa values = 0. 640 for DSR of digital images; and 0. 574 for DSR of digitized images. There was 100% intrarater agreement at time 0. Sensitivity of both modalities was statistically different in relation to experimental times. Time 6 had the highest values (digital: 1. 000; digitized: 0. 961), while time 2 showed the lowest values (0. 688 and 0. 714). Irrespective of the imaging method, the proportion of correct responses significantly increased regarding experimental times. Specificity was high for DSR of both digitized (0. 896) and digital (0,844) images. Accuracy in time 6 was higher than that of other times, both for the digitized (0. 929) and digital (0. 922) modalities. DSR of panoramic images, both digitized and digital, allows for detection of incipient periapical lesions, with satisfactory sensitivity and specificity values.
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spelling Miguens Júnior, Sergio Augusto QuevedoVeeck, Elaine Bauer2011-12-27T14:14:08Z2011-12-27T14:14:08Z2008http://hdl.handle.net/10923/398This thesis comprises two articles. In the first article, we assessed in vitro the ability of digital subtraction radiography (DSR) in the detection of incipient periapical lesions using panoramic digital and digitized radiographs. Periapical defects were created in dried human mandibles through application of 70% perchloric acid at times 2, 4, and 6 hours. Conventional and digital radiographs were obtained twice at time zero, with the aim of evaluating reproducibility of this technique, and sequentially before each application of the acid solution. Conventional radiographs were digitized using a scanner with the same attributes than direct digital radiographs: 150-dpi resolution, 8-bit mode and stored as non-compressed TIFF format. The software Adobe Photoshop® was used for DSR of the images in the following sequence: T0x0 repeated; T0xT2; T0xT4; and T0xT6. The variable under analysis was the difference between pixel intensity in control and test areas. Using ANOVA to compare the size of the areas marked to obtain pixel intensity values in different experimental times, no differences were observed between times both for the test (F= 0. 44; P = 0. 726) and for the control area (F= 1. 20; P = 0. 310). Comparing experimental times, there were significant differences, time 6 having the highest mean of mineral loss. Times 2 and 4 had no differences, but were significantly higher than time 0, both for digitized (F= 45. 01; P< 0. 001) and for digital images (F= 30. 80; P < 0. 001). We concluded that DSR of panoramic radiographic images, whether digital or digitized, allows for detection of incipient periapical defects. In the second article, we compared in vitro specificity, sensitivity, and diagnostic accuracy of digital subtraction radiography (DSR) in digital and digitized panoramic images in the detection of incipient periapical lesions. The images were assessed by an experienced and blinded observer, who attributed scores 0 (absence of image representing mineral loss) or 1 (presence of dark image representing mineral loss) to each image. Results were evaluated using analysis of variance (ANOVA), complemented by Dunnett’s T3 multiple comparison test; the level of significance was set at 5%. The observer showed Kappa values = 0. 640 for DSR of digital images; and 0. 574 for DSR of digitized images. There was 100% intrarater agreement at time 0. Sensitivity of both modalities was statistically different in relation to experimental times. Time 6 had the highest values (digital: 1. 000; digitized: 0. 961), while time 2 showed the lowest values (0. 688 and 0. 714). Irrespective of the imaging method, the proportion of correct responses significantly increased regarding experimental times. Specificity was high for DSR of both digitized (0. 896) and digital (0,844) images. Accuracy in time 6 was higher than that of other times, both for the digitized (0. 929) and digital (0. 922) modalities. DSR of panoramic images, both digitized and digital, allows for detection of incipient periapical lesions, with satisfactory sensitivity and specificity values.Esta tese é apresentada sob a forma de dois artigos. O artigo I avaliou, in vitro, a capacidade da subtração radiográfica digital (SRD) na detecção de lesões periapicais incipientes em radiografias panorâmicas digitais e digitalizadas. Foram criados defeitos periapicais em mandíbulas humanas secas pela aplicação de ácido perclórico a 70%, nos tempos 2, 4 e 6 horas. As radiografias convencionais e digitais foram obtidas duas vezes no tempo zero, com intenção de avaliar a reprodutibilidade da técnica, e, seqüencialmente, antes de cada aplicação da solução ácida. As radiografias convencionais foram digitalizadas em scanner com os mesmos atributos que as digitais diretas: resolução de 150 dpi, 8 bits e armazenadas em formato TIFF sem compressão. O programa Adobe Photoshop® foi utilizado para a SRD das imagens, na seguinte seqüência: T0x0 repetido; T0xT2; T0xT4 e T0xT6. A variável analisada foi a diferença entre a intensidade de pixel das áreas controle e teste. Comparando o tamanho da área delimitada para a obtenção dos valores de intensidade de pixels nos diferentes tempos experimentais observou-se, por meio da ANOVA, não haver diferença entre os tempos tanto para a área-teste (F= 0,44; p=0,726) quanto para a área-controle (F=1,20; p=0,310). Comparando os tempos experimentais observou-se que existiu diferença significativa entre eles, sendo o tempo 6 o que apresentou maior média de expressão de perda mineral. Os tempos 2 e 4 não diferiram entre si, porém foram significativamente maiores que o tempo 0, tanto nas imagens digitalizadas (F= 45,01; p<0,001) quanto nas digitais (F= 30,80; p<0,001). Concluiu-se que a SRD de imagens radiográficas panorâmicas, tanto digitais quanto digitalizadas, permite a detecção de defeitos periapicais incipientes.O artigo II comparou, in vitro, a especificidade, sensibilidade e acurácia diagnóstica das radiografias panorâmicas digitais e digitalizadas na detecção por SRD de lesões periapicais incipientes. As imagens foram avaliadas por um observador experiente, cego quanto ao tipo de imagem e grupo que lhes atribuiu escore 0 (ausência de imagem representativa de perda mineral) ou 1 (presença de imagem escura de perda mineral). Os resultados foram avaliados por meio da ANOVA, complementada pelo Teste de Comparações Múltiplas de Dunnett T3, com α=5%. O observador apresentou coeficiente de Kappa = 0,640 para a SRD em imagens digitais e 0,574 para as digitalizadas. No tempo 0 houve 100% de concordância intra-examinador. A sensibilidade de ambas as modalidades foi estatisticamente diferente em relação aos tempos experimentais. O tempo 6 apresentou o maior valor (digitais: 1,000; digitalizadas: 0,961), enquanto o tempo 2 apresentou os menores valores (0,688 e 0,714). Independente do método de imagem, a proporção de acertos aumentou significativamente em relação aos tempos experimentais. A especificidade foi alta tanto para a SRD em imagens digitalizadas (0,896) quanto para as digitais (0,844). A acurácia no tempo 6, tanto na modalidade digitalizada (0,929) como na digital (0,922), foi superior aos demais tempos. A SRD em radiografias panorâmicas, tanto digitalizadas como digitais, permite detectar lesões periapicais incipientes, com valores de sensibilidade e especificidade satisfatórios.Made available in DSpace on 2011-12-27T14:14:08Z (GMT). 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dc.title.pt_BR.fl_str_mv Detecção de lesões periapicais incipientes por subtração radiográfica com imagens panorâmicas digitais e digitalizadas
title Detecção de lesões periapicais incipientes por subtração radiográfica com imagens panorâmicas digitais e digitalizadas
spellingShingle Detecção de lesões periapicais incipientes por subtração radiográfica com imagens panorâmicas digitais e digitalizadas
Miguens Júnior, Sergio Augusto Quevedo
LESÕES PERIAPICAIS
RADIOGRAFIA DIGITAL
RADIOGRAFIA PANORÂMICA
DIAGNÓSTICO POR IMAGEM
title_short Detecção de lesões periapicais incipientes por subtração radiográfica com imagens panorâmicas digitais e digitalizadas
title_full Detecção de lesões periapicais incipientes por subtração radiográfica com imagens panorâmicas digitais e digitalizadas
title_fullStr Detecção de lesões periapicais incipientes por subtração radiográfica com imagens panorâmicas digitais e digitalizadas
title_full_unstemmed Detecção de lesões periapicais incipientes por subtração radiográfica com imagens panorâmicas digitais e digitalizadas
title_sort Detecção de lesões periapicais incipientes por subtração radiográfica com imagens panorâmicas digitais e digitalizadas
author Miguens Júnior, Sergio Augusto Quevedo
author_facet Miguens Júnior, Sergio Augusto Quevedo
author_role author
dc.contributor.author.fl_str_mv Miguens Júnior, Sergio Augusto Quevedo
dc.contributor.advisor1.fl_str_mv Veeck, Elaine Bauer
contributor_str_mv Veeck, Elaine Bauer
dc.subject.por.fl_str_mv LESÕES PERIAPICAIS
RADIOGRAFIA DIGITAL
RADIOGRAFIA PANORÂMICA
DIAGNÓSTICO POR IMAGEM
topic LESÕES PERIAPICAIS
RADIOGRAFIA DIGITAL
RADIOGRAFIA PANORÂMICA
DIAGNÓSTICO POR IMAGEM
description This thesis comprises two articles. In the first article, we assessed in vitro the ability of digital subtraction radiography (DSR) in the detection of incipient periapical lesions using panoramic digital and digitized radiographs. Periapical defects were created in dried human mandibles through application of 70% perchloric acid at times 2, 4, and 6 hours. Conventional and digital radiographs were obtained twice at time zero, with the aim of evaluating reproducibility of this technique, and sequentially before each application of the acid solution. Conventional radiographs were digitized using a scanner with the same attributes than direct digital radiographs: 150-dpi resolution, 8-bit mode and stored as non-compressed TIFF format. The software Adobe Photoshop® was used for DSR of the images in the following sequence: T0x0 repeated; T0xT2; T0xT4; and T0xT6. The variable under analysis was the difference between pixel intensity in control and test areas. Using ANOVA to compare the size of the areas marked to obtain pixel intensity values in different experimental times, no differences were observed between times both for the test (F= 0. 44; P = 0. 726) and for the control area (F= 1. 20; P = 0. 310). Comparing experimental times, there were significant differences, time 6 having the highest mean of mineral loss. Times 2 and 4 had no differences, but were significantly higher than time 0, both for digitized (F= 45. 01; P< 0. 001) and for digital images (F= 30. 80; P < 0. 001). We concluded that DSR of panoramic radiographic images, whether digital or digitized, allows for detection of incipient periapical defects. In the second article, we compared in vitro specificity, sensitivity, and diagnostic accuracy of digital subtraction radiography (DSR) in digital and digitized panoramic images in the detection of incipient periapical lesions. The images were assessed by an experienced and blinded observer, who attributed scores 0 (absence of image representing mineral loss) or 1 (presence of dark image representing mineral loss) to each image. Results were evaluated using analysis of variance (ANOVA), complemented by Dunnett’s T3 multiple comparison test; the level of significance was set at 5%. The observer showed Kappa values = 0. 640 for DSR of digital images; and 0. 574 for DSR of digitized images. There was 100% intrarater agreement at time 0. Sensitivity of both modalities was statistically different in relation to experimental times. Time 6 had the highest values (digital: 1. 000; digitized: 0. 961), while time 2 showed the lowest values (0. 688 and 0. 714). Irrespective of the imaging method, the proportion of correct responses significantly increased regarding experimental times. Specificity was high for DSR of both digitized (0. 896) and digital (0,844) images. Accuracy in time 6 was higher than that of other times, both for the digitized (0. 929) and digital (0. 922) modalities. DSR of panoramic images, both digitized and digital, allows for detection of incipient periapical lesions, with satisfactory sensitivity and specificity values.
publishDate 2008
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Porto Alegre
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Porto Alegre
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