Vitamin D concentrations and their relationship with iron parameters in patients with chronic kidney disease

Detalhes bibliográficos
Autor(a) principal: VIANA, Letícya Thaís Mendes
Data de Publicação: 2023
Outros Autores: FREITAS, Betânia de Jesus e Silva de Almendra
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista de Nutrição
Texto Completo: https://periodicos.puc-campinas.edu.br/nutricao/article/view/7562
Resumo: ObjectiveTo investigate the relationship between calcidiol (25(OH)D3) concentrations and iron parameters in patients with chronic kidney disease.MethodsThis is a cross-sectional, descriptive, and quantitative study. The sample consisted of 86 adult patients of both sexes undergoing dialysis. 25(OH)D3 concentrations were determined by chemiluminescence; food consumption was assessed using 24-hour recalls, and the serum levels of hemoglobin, iron, ferritin, and transferrin saturation were assessed. Data analysis was performed using the program Stata, with a significance level of p<0.05.ResultsThe results pointed to 25(OH)D3 concentrations compatible with sufficiency, iron levels consistent with normality, and ferritin and transferrin saturation above the reference values. The consumption of carbohydrates and lipids was higher in females. There was no relationship between the adequacy of 25(OH)D3 and the presence of anemia and iron parameters.ConclusionConsidering that the mean serum levels of iron and 25(OH)D3 were adequate, it is suggested that resistance to erythropoietin and the inflammatory process may have contributed to the percentage of anemic individuals found in the study.
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spelling Vitamin D concentrations and their relationship with iron parameters in patients with chronic kidney diseaseConcentrações de vitamina D e sua relação com parâmetros de ferro em pacientes com doença renal crônicaAnemiaCholecalciferolChronic kidney disease-mineral and bone disorderIronRenal dialysisAnemiaColecalciferolDistúrbio mineral e ósseo na doença renal crônicaFerroDiálise renalObjectiveTo investigate the relationship between calcidiol (25(OH)D3) concentrations and iron parameters in patients with chronic kidney disease.MethodsThis is a cross-sectional, descriptive, and quantitative study. The sample consisted of 86 adult patients of both sexes undergoing dialysis. 25(OH)D3 concentrations were determined by chemiluminescence; food consumption was assessed using 24-hour recalls, and the serum levels of hemoglobin, iron, ferritin, and transferrin saturation were assessed. Data analysis was performed using the program Stata, with a significance level of p<0.05.ResultsThe results pointed to 25(OH)D3 concentrations compatible with sufficiency, iron levels consistent with normality, and ferritin and transferrin saturation above the reference values. The consumption of carbohydrates and lipids was higher in females. There was no relationship between the adequacy of 25(OH)D3 and the presence of anemia and iron parameters.ConclusionConsidering that the mean serum levels of iron and 25(OH)D3 were adequate, it is suggested that resistance to erythropoietin and the inflammatory process may have contributed to the percentage of anemic individuals found in the study.ObjetivoInvestigar a relação entre as concentrações de calcidiol (25(OH)D3) e os parâmetros de ferro em pacientes com doença renal crônica.MétodosÉ um estudo transversal, descritivo e quantitativo. A amostra foi composta por 86 pacientes, adultos, de ambos os sexos, em terapia dialítica. As concentrações de 25(OH)D3 foram determinadas pelo método de quimioluminescência; o consumo alimentar foi avaliado pela aplicação de Recordatórios de 24 horas e foram avaliados os níveis séricos de hemoglobina, ferro, ferritina e saturação de transferrina. A análise dos dados foi realizada no programa Stata, com nível de significância p<0.05.ResultadosOs resultados apontaram para concentrações de 25(OH)D3 compatíveis com suficiência, níveis de ferro compatíveis com a normalidade e ferritina e saturação de transferrina superiores à referência. O consumo de carboidratos e lipídios foi superior no sexo feminino. Não foi verificada relação entre a adequação de 25(OH)D3 e a presença de anemia e parâmetros de ferro.ConclusãoTendo em vista que os níveis médios séricos de ferro e 25(OH)D3 estavam adequados, sugere-se que a resistência à eritropoietina e o processo inflamatório podem ter contribuído para o percentual de anêmicos constatado no estudo. Núcleo de Editoração – PUC-Campinas2023-03-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://periodicos.puc-campinas.edu.br/nutricao/article/view/7562Brazilian Journal of Nutrition; Vol. 35 (2022): Revista de Nutrição; 1-10Revista de Nutrição; Vol. 35 (2022): Revista de Nutrição; 1-10Revista de Nutrição; v. 35 (2022): Revista de Nutrição; 1-101678-9865reponame:Revista de Nutriçãoinstname:Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS)instacron:PUC_CAMPenghttps://periodicos.puc-campinas.edu.br/nutricao/article/view/7562/5104https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessVIANA, Letícya Thaís MendesFREITAS, Betânia de Jesus e Silva de Almendra2023-10-06T18:55:02Zoai:ojs.periodicos.puc-campinas.edu.br:article/7562Revistahttp://www.scielo.br/rnPRIhttps://periodicos.puc-campinas.edu.br/nutricao/oai||sbi.submissionrn@puc-campinas.edu.br1678-98651415-5273opendoar:2023-10-06T18:55:02Revista de Nutrição - Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS)false
dc.title.none.fl_str_mv Vitamin D concentrations and their relationship with iron parameters in patients with chronic kidney disease
Concentrações de vitamina D e sua relação com parâmetros de ferro em pacientes com doença renal crônica
title Vitamin D concentrations and their relationship with iron parameters in patients with chronic kidney disease
spellingShingle Vitamin D concentrations and their relationship with iron parameters in patients with chronic kidney disease
VIANA, Letícya Thaís Mendes
Anemia
Cholecalciferol
Chronic kidney disease-mineral and bone disorder
Iron
Renal dialysis
Anemia
Colecalciferol
Distúrbio mineral e ósseo na doença renal crônica
Ferro
Diálise renal
title_short Vitamin D concentrations and their relationship with iron parameters in patients with chronic kidney disease
title_full Vitamin D concentrations and their relationship with iron parameters in patients with chronic kidney disease
title_fullStr Vitamin D concentrations and their relationship with iron parameters in patients with chronic kidney disease
title_full_unstemmed Vitamin D concentrations and their relationship with iron parameters in patients with chronic kidney disease
title_sort Vitamin D concentrations and their relationship with iron parameters in patients with chronic kidney disease
author VIANA, Letícya Thaís Mendes
author_facet VIANA, Letícya Thaís Mendes
FREITAS, Betânia de Jesus e Silva de Almendra
author_role author
author2 FREITAS, Betânia de Jesus e Silva de Almendra
author2_role author
dc.contributor.author.fl_str_mv VIANA, Letícya Thaís Mendes
FREITAS, Betânia de Jesus e Silva de Almendra
dc.subject.por.fl_str_mv Anemia
Cholecalciferol
Chronic kidney disease-mineral and bone disorder
Iron
Renal dialysis
Anemia
Colecalciferol
Distúrbio mineral e ósseo na doença renal crônica
Ferro
Diálise renal
topic Anemia
Cholecalciferol
Chronic kidney disease-mineral and bone disorder
Iron
Renal dialysis
Anemia
Colecalciferol
Distúrbio mineral e ósseo na doença renal crônica
Ferro
Diálise renal
description ObjectiveTo investigate the relationship between calcidiol (25(OH)D3) concentrations and iron parameters in patients with chronic kidney disease.MethodsThis is a cross-sectional, descriptive, and quantitative study. The sample consisted of 86 adult patients of both sexes undergoing dialysis. 25(OH)D3 concentrations were determined by chemiluminescence; food consumption was assessed using 24-hour recalls, and the serum levels of hemoglobin, iron, ferritin, and transferrin saturation were assessed. Data analysis was performed using the program Stata, with a significance level of p<0.05.ResultsThe results pointed to 25(OH)D3 concentrations compatible with sufficiency, iron levels consistent with normality, and ferritin and transferrin saturation above the reference values. The consumption of carbohydrates and lipids was higher in females. There was no relationship between the adequacy of 25(OH)D3 and the presence of anemia and iron parameters.ConclusionConsidering that the mean serum levels of iron and 25(OH)D3 were adequate, it is suggested that resistance to erythropoietin and the inflammatory process may have contributed to the percentage of anemic individuals found in the study.
publishDate 2023
dc.date.none.fl_str_mv 2023-03-06
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.puc-campinas.edu.br/nutricao/article/view/7562
url https://periodicos.puc-campinas.edu.br/nutricao/article/view/7562
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://periodicos.puc-campinas.edu.br/nutricao/article/view/7562/5104
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Núcleo de Editoração – PUC-Campinas
publisher.none.fl_str_mv Núcleo de Editoração – PUC-Campinas
dc.source.none.fl_str_mv Brazilian Journal of Nutrition; Vol. 35 (2022): Revista de Nutrição; 1-10
Revista de Nutrição; Vol. 35 (2022): Revista de Nutrição; 1-10
Revista de Nutrição; v. 35 (2022): Revista de Nutrição; 1-10
1678-9865
reponame:Revista de Nutrição
instname:Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS)
instacron:PUC_CAMP
instname_str Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS)
instacron_str PUC_CAMP
institution PUC_CAMP
reponame_str Revista de Nutrição
collection Revista de Nutrição
repository.name.fl_str_mv Revista de Nutrição - Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS)
repository.mail.fl_str_mv ||sbi.submissionrn@puc-campinas.edu.br
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