Relationship between vitamin A and biochemical markers of iron status in children and adolescents

• Autor(a) principal: Ribeiro SILVA, Rita de Cássia
• Data de Publicação: 2023
• Outros Autores: Oliveira ASSIS, Ana Marlúcia, Portela de SANTANA, Mônica Leila, Lima BARRETO, Maurício, Leite BRITO, Luciara, Galvão REIS, Mitermayer, Martin PARRAGA, Isabel, BLANTON, Ronald Edward
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Revista de Nutrição
• Texto Completo: https://periodicos.puc-campinas.edu.br/nutricao/article/view/9583
• topic: Adolescent; Child; Iron deficiency; Vitamin A deficiency; Adolescente; Criança; Deficiência de ferro; Deficiência de vitamina A

ObjectiveThe objective of this study was to verify the relationship between vitamin A and the biochemical markers of iron status. MethodsA total of 178 individuals aging from 7 to 17 years participated in this study, all living in Jequié, BA. The individuals were submitted to blood tests to dose retinol and biochemical iron markers. Furthermore, anthropometric measurements and stool analyses were done and dietary information regarding iron intake, socio-environmental and home conditions of the family were collected. Multiple linear regression analysis was done to assess the association of interest. ResultsA positive and statistically significant association was found between the levels of serum retinol and hemoglobin (p=0.007), serum iron (p=0.010) and iron-saturated tranferrin (p=0.027). These findings remained unchanged after adjusting the models for demographic variables, parasitic infections (Schistosoma mansoni, Trichiura trichuris, Ascaris lumbricoides and ancylostomiasis), consumption of bioavailable dietary iron and environmental and home conditions. ConclusionVitamin A seems to contribute to the increase of organic iron of the population, especially in areas were deficiency of vitamin A and iron-deficiency anemia coexist.