Bifidogenic effect of fructooligosaccharides in the intestinal flora of patients with hematological neoplasia

Detalhes bibliográficos
Autor(a) principal: BÚRIGO, Telma
Data de Publicação: 2023
Outros Autores: Martins FAGUNDES, Regina Lúcia, Santos de Moraes TRINDADE, Erasmo Benicio, Ferreira Franz VASCONCELOS, Helena Cristina
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista de Nutrição
Texto Completo: https://periodicos.puc-campinas.edu.br/nutricao/article/view/9706
Resumo: ObjectiveTo verify the bifidogenic effect of fructooligosaccharides in patients with hematological neoplasia submitted to chemotherapy. MethodsThis is a clinical, randomized, double-blind study done in the Bone Marrow Transplant Unit of the Oncology Research Center of Florianopolis. It involved 25 patients divided into 2 groups who received 12g of fructooligosaccharides (n=14) for 15 days or placebo (maltodextrin) (n=11). The amount of bifidobacteria and the values of fecal pH before and after supplementation were investigated. ResultsMost of the studied population was male (72%) and the mean age was 34 years. The group that received supplementation presented a significant increase in the amount of bifidobacteria (p<0.05) and fecal pH remained unchanged in both groups. ConclusionSupplementation increased the amount of bifidobacteria, interfering in the composition of the intestinal flora, but fecal pH was not affected.
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spelling Bifidogenic effect of fructooligosaccharides in the intestinal flora of patients with hematological neoplasiaEfeito bifidogênico do frutooligossacarídeo na microbiota intestinal de pacientes com neoplasia hematológicabifidogenic microbiotafructooligosaccharidehematologic neoplasmsbifidobactériamicrobiotafrutooligossacarídeosneoplasias hematológicasObjectiveTo verify the bifidogenic effect of fructooligosaccharides in patients with hematological neoplasia submitted to chemotherapy. MethodsThis is a clinical, randomized, double-blind study done in the Bone Marrow Transplant Unit of the Oncology Research Center of Florianopolis. It involved 25 patients divided into 2 groups who received 12g of fructooligosaccharides (n=14) for 15 days or placebo (maltodextrin) (n=11). The amount of bifidobacteria and the values of fecal pH before and after supplementation were investigated. ResultsMost of the studied population was male (72%) and the mean age was 34 years. The group that received supplementation presented a significant increase in the amount of bifidobacteria (p<0.05) and fecal pH remained unchanged in both groups. ConclusionSupplementation increased the amount of bifidobacteria, interfering in the composition of the intestinal flora, but fecal pH was not affected.ObjetivoVerificar o efeito bifidogênico do frutooligossacarídeo nos pacientes com neoplasias hematológicas submetidos a quimioterapia. MétodosTrata-se de um estudo clínico randomizado duplo cego, desenvolvido na Unidade de Transplante de Medula Óssea do Centro de Pesquisas Oncológicas de Florianópolis, o qual envolve 25 pacientes divididos em 2 grupos que receberam, por 15 dias, 12g de frutooligossacarídeo (n=14) ou placebo (maltodextrina) (n=11). Foram avaliados a quantidade de bifidobactérias e os valores de pH fecal antes e após a suplementação. ResultadosObservou-se na população estudada o predomínio do sexo masculino (72%) e a idade média de 34 anos. O grupo suplementado apresentou um aumento significante na quantidade de bifidobactérias (p<0,05) e o pH fecal não foi alterado em nenhum dos grupos. ConclusãoVerificou-se que a suplementação aumentou a quantidade de bifidobactérias, interferindo na composição da microbiota intestinal, e que não houve alteração do pH fecal. Núcleo de Editoração – PUC-Campinas2023-09-15info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://periodicos.puc-campinas.edu.br/nutricao/article/view/9706Brazilian Journal of Nutrition; Vol. 20 No. 5 (2007): Revista de NutriçãoRevista de Nutrição; Vol. 20 Núm. 5 (2007): Revista de NutriçãoRevista de Nutrição; v. 20 n. 5 (2007): Revista de Nutrição1678-9865reponame:Revista de Nutriçãoinstname:Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS)instacron:PUC_CAMPporhttps://periodicos.puc-campinas.edu.br/nutricao/article/view/9706/7053Copyright (c) 2023 Telma BÚRIGO, Regina Lúcia Martins FAGUNDES, Erasmo Benicio Santos de Moraes TRINDADE, Helena Cristina Ferreira Franz VASCONCELOShttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessBÚRIGO, TelmaMartins FAGUNDES, Regina Lúcia Santos de Moraes TRINDADE, Erasmo BenicioFerreira Franz VASCONCELOS, Helena Cristina 2023-10-05T18:45:02Zoai:ojs.periodicos.puc-campinas.edu.br:article/9706Revistahttp://www.scielo.br/rnPRIhttps://periodicos.puc-campinas.edu.br/nutricao/oai||sbi.submissionrn@puc-campinas.edu.br1678-98651415-5273opendoar:2023-10-05T18:45:02Revista de Nutrição - Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS)false
dc.title.none.fl_str_mv Bifidogenic effect of fructooligosaccharides in the intestinal flora of patients with hematological neoplasia
Efeito bifidogênico do frutooligossacarídeo na microbiota intestinal de pacientes com neoplasia hematológica
title Bifidogenic effect of fructooligosaccharides in the intestinal flora of patients with hematological neoplasia
spellingShingle Bifidogenic effect of fructooligosaccharides in the intestinal flora of patients with hematological neoplasia
BÚRIGO, Telma
bifidogenic microbiota
fructooligosaccharide
hematologic neoplasms
bifidobactéria
microbiota
frutooligossacarídeos
neoplasias hematológicas
title_short Bifidogenic effect of fructooligosaccharides in the intestinal flora of patients with hematological neoplasia
title_full Bifidogenic effect of fructooligosaccharides in the intestinal flora of patients with hematological neoplasia
title_fullStr Bifidogenic effect of fructooligosaccharides in the intestinal flora of patients with hematological neoplasia
title_full_unstemmed Bifidogenic effect of fructooligosaccharides in the intestinal flora of patients with hematological neoplasia
title_sort Bifidogenic effect of fructooligosaccharides in the intestinal flora of patients with hematological neoplasia
author BÚRIGO, Telma
author_facet BÚRIGO, Telma
Martins FAGUNDES, Regina Lúcia
Santos de Moraes TRINDADE, Erasmo Benicio
Ferreira Franz VASCONCELOS, Helena Cristina
author_role author
author2 Martins FAGUNDES, Regina Lúcia
Santos de Moraes TRINDADE, Erasmo Benicio
Ferreira Franz VASCONCELOS, Helena Cristina
author2_role author
author
author
dc.contributor.author.fl_str_mv BÚRIGO, Telma
Martins FAGUNDES, Regina Lúcia
Santos de Moraes TRINDADE, Erasmo Benicio
Ferreira Franz VASCONCELOS, Helena Cristina
dc.subject.por.fl_str_mv bifidogenic microbiota
fructooligosaccharide
hematologic neoplasms
bifidobactéria
microbiota
frutooligossacarídeos
neoplasias hematológicas
topic bifidogenic microbiota
fructooligosaccharide
hematologic neoplasms
bifidobactéria
microbiota
frutooligossacarídeos
neoplasias hematológicas
description ObjectiveTo verify the bifidogenic effect of fructooligosaccharides in patients with hematological neoplasia submitted to chemotherapy. MethodsThis is a clinical, randomized, double-blind study done in the Bone Marrow Transplant Unit of the Oncology Research Center of Florianopolis. It involved 25 patients divided into 2 groups who received 12g of fructooligosaccharides (n=14) for 15 days or placebo (maltodextrin) (n=11). The amount of bifidobacteria and the values of fecal pH before and after supplementation were investigated. ResultsMost of the studied population was male (72%) and the mean age was 34 years. The group that received supplementation presented a significant increase in the amount of bifidobacteria (p<0.05) and fecal pH remained unchanged in both groups. ConclusionSupplementation increased the amount of bifidobacteria, interfering in the composition of the intestinal flora, but fecal pH was not affected.
publishDate 2023
dc.date.none.fl_str_mv 2023-09-15
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
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dc.identifier.uri.fl_str_mv https://periodicos.puc-campinas.edu.br/nutricao/article/view/9706
url https://periodicos.puc-campinas.edu.br/nutricao/article/view/9706
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://periodicos.puc-campinas.edu.br/nutricao/article/view/9706/7053
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Núcleo de Editoração – PUC-Campinas
publisher.none.fl_str_mv Núcleo de Editoração – PUC-Campinas
dc.source.none.fl_str_mv Brazilian Journal of Nutrition; Vol. 20 No. 5 (2007): Revista de Nutrição
Revista de Nutrição; Vol. 20 Núm. 5 (2007): Revista de Nutrição
Revista de Nutrição; v. 20 n. 5 (2007): Revista de Nutrição
1678-9865
reponame:Revista de Nutrição
instname:Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS)
instacron:PUC_CAMP
instname_str Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS)
instacron_str PUC_CAMP
institution PUC_CAMP
reponame_str Revista de Nutrição
collection Revista de Nutrição
repository.name.fl_str_mv Revista de Nutrição - Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS)
repository.mail.fl_str_mv ||sbi.submissionrn@puc-campinas.edu.br
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