Effect of flaxseed (Linum usitatissimum L.) prepared by different methods on the biological response of rats

Detalhes bibliográficos
Autor(a) principal: MARQUES, Anne y Castro
Data de Publicação: 2023
Outros Autores: HAUTRIVE, Tiffany Prokopp, MOURA, Guilherme Barcellos de, CALLEGARO, Maria da Graça Kolinski, HECKTHEUER, Luisa Helena Rychecki
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista de Nutrição
Texto Completo: https://periodicos.puc-campinas.edu.br/nutricao/article/view/9292
Resumo: ObjectiveThe objective of this investigation was to evaluate the effects of flaxseed (Linum usitatissimum L.) prepared by different methods on the biological response of rats.MethodsWeaned rats (n=32) were divided into 4 groups of 8 animals each: standard feed, standard feed with 16% raw flaxseed, standard feed with 16% roasted flaxseed and standard feed with 7% flaxseed oil. The animals were weighted at every 3 days and after 23 days, rats were killed by heart puncture. The organs were immediately weighed and the blood was collected and stored at -18ºC for biochemical assays (blood glucose, total cholesterol, High density lipoprotein cholesterol, triglyceride and total protein). The feces were collected for analysis of moisture, excreted lipids and absorbed lipids.ResultsThe groups did not differ with respect to weight gain, daily food intake, food efficiency ratio and organ weight. Daily excretion, feces moisture and fecal lipid content were greater in the groups fed raw and roasted flaxseed than in the groups fed standard feed and flaxseed oil. Except for high density lipoprotein-cholesterol, all other biochemical parameters presented statistical differences between treatments.ConclusionRaw or roasted flaxseed or flaxseed oil has biological activity in rats: it reduces blood glucose, triglyceride and cholesterol levels. Furthermore, rats fed raw and roasted flaxseed presented a significantly greater fecal volume and fecal lipid content
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spelling Effect of flaxseed (Linum usitatissimum L.) prepared by different methods on the biological response of ratsEfeito da linhaça (Linum usitatissimum L.) sob diferentes formas de preparo na resposta biológica em ratosAlpha-linolenic acidFlaxRatsÁcido alfa-linolênicoLinhoRatosObjectiveThe objective of this investigation was to evaluate the effects of flaxseed (Linum usitatissimum L.) prepared by different methods on the biological response of rats.MethodsWeaned rats (n=32) were divided into 4 groups of 8 animals each: standard feed, standard feed with 16% raw flaxseed, standard feed with 16% roasted flaxseed and standard feed with 7% flaxseed oil. The animals were weighted at every 3 days and after 23 days, rats were killed by heart puncture. The organs were immediately weighed and the blood was collected and stored at -18ºC for biochemical assays (blood glucose, total cholesterol, High density lipoprotein cholesterol, triglyceride and total protein). The feces were collected for analysis of moisture, excreted lipids and absorbed lipids.ResultsThe groups did not differ with respect to weight gain, daily food intake, food efficiency ratio and organ weight. Daily excretion, feces moisture and fecal lipid content were greater in the groups fed raw and roasted flaxseed than in the groups fed standard feed and flaxseed oil. Except for high density lipoprotein-cholesterol, all other biochemical parameters presented statistical differences between treatments.ConclusionRaw or roasted flaxseed or flaxseed oil has biological activity in rats: it reduces blood glucose, triglyceride and cholesterol levels. Furthermore, rats fed raw and roasted flaxseed presented a significantly greater fecal volume and fecal lipid contentObjetivoVerificar as possíveis atividades biológicas causadas pelo consumo diário de linhaça em diferentes condições de preparo, em ratos Wistar machos recém-desmamados.MétodosOs ratos recém-desmamados (n=32) foram divididos em 4 grupos de 8 animais: ração padrão; ração com 16% de grão de linhaça cru; ração com 16% de grão de linhaça assado; e ração com 7% de óleo de linhaça. Os animais foram pesados a cada três dias e, após 23 dias de período experimental, foram sacrificados por punção cardíaca, sendo os órgãos imediatamente pesados e o sangue coletado e armazenado a -18ºC para realização das análises (glicose, colesterol total, lipoproteína de alta densidade-colesterol, triglicerídios e proteínas totais). As fezes foram coletadas para a determinação de umidade, lipídeo excretado e lipídeo absorvido.ResultadosNão houve diferença entre os grupos quanto ao ganho de peso total, consumo diário, coeficiente de eficácia alimentar e peso dos órgãos. A excreção diária, o teor de umidade das fezes e a quantidade de lipídeo fecal foram maiores nos grupos linhaça cru e linhaça assada em comparação aos grupos padrão e óleo de linhaça. Com exceção do lipoproteína de alta densidade-colesterol, todos os demais parâmetros bioquímicos avaliados apresentaram diferenças estatísticas entre os tratamentos.ConclusãoO consumo de linhaça, seja como grão cru, assado ou óleo, possui atividade biológica em ratos, destacando-se por reduzir os níveis de glicose, triglicerídios e colesterol. Além disso, o consumo do grão de linhaça aumentou significativamente o volume do bolo fecal e a excreção de lipídeos nas fezes.Núcleo de Editoração – PUC-Campinas2023-08-23info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://periodicos.puc-campinas.edu.br/nutricao/article/view/9292Brazilian Journal of Nutrition; Vol. 24 No. 1 (2011): Revista de NutriçãoRevista de Nutrição; Vol. 24 Núm. 1 (2011): Revista de NutriçãoRevista de Nutrição; v. 24 n. 1 (2011): Revista de Nutrição1678-9865reponame:Revista de Nutriçãoinstname:Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS)instacron:PUC_CAMPporhttps://periodicos.puc-campinas.edu.br/nutricao/article/view/9292/6669Copyright (c) 2023 Anne y Castro MARQUES, Tiffany Prokopp HAUTRIVE, Guilherme Barcellos de MOURA, Maria da Graça Kolinski CALLEGARO, Luisa Helena Rychecki HECKTHEUERhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessMARQUES, Anne y Castro HAUTRIVE, Tiffany Prokopp MOURA, Guilherme Barcellos de CALLEGARO, Maria da Graça Kolinski HECKTHEUER, Luisa Helena Rychecki 2023-12-05T17:27:49Zoai:ojs.periodicos.puc-campinas.edu.br:article/9292Revistahttp://www.scielo.br/rnPRIhttps://periodicos.puc-campinas.edu.br/nutricao/oai||sbi.submissionrn@puc-campinas.edu.br1678-98651415-5273opendoar:2023-12-05T17:27:49Revista de Nutrição - Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS)false
dc.title.none.fl_str_mv Effect of flaxseed (Linum usitatissimum L.) prepared by different methods on the biological response of rats
Efeito da linhaça (Linum usitatissimum L.) sob diferentes formas de preparo na resposta biológica em ratos
title Effect of flaxseed (Linum usitatissimum L.) prepared by different methods on the biological response of rats
spellingShingle Effect of flaxseed (Linum usitatissimum L.) prepared by different methods on the biological response of rats
MARQUES, Anne y Castro
Alpha-linolenic acid
Flax
Rats
Ácido alfa-linolênico
Linho
Ratos
title_short Effect of flaxseed (Linum usitatissimum L.) prepared by different methods on the biological response of rats
title_full Effect of flaxseed (Linum usitatissimum L.) prepared by different methods on the biological response of rats
title_fullStr Effect of flaxseed (Linum usitatissimum L.) prepared by different methods on the biological response of rats
title_full_unstemmed Effect of flaxseed (Linum usitatissimum L.) prepared by different methods on the biological response of rats
title_sort Effect of flaxseed (Linum usitatissimum L.) prepared by different methods on the biological response of rats
author MARQUES, Anne y Castro
author_facet MARQUES, Anne y Castro
HAUTRIVE, Tiffany Prokopp
MOURA, Guilherme Barcellos de
CALLEGARO, Maria da Graça Kolinski
HECKTHEUER, Luisa Helena Rychecki
author_role author
author2 HAUTRIVE, Tiffany Prokopp
MOURA, Guilherme Barcellos de
CALLEGARO, Maria da Graça Kolinski
HECKTHEUER, Luisa Helena Rychecki
author2_role author
author
author
author
dc.contributor.author.fl_str_mv MARQUES, Anne y Castro
HAUTRIVE, Tiffany Prokopp
MOURA, Guilherme Barcellos de
CALLEGARO, Maria da Graça Kolinski
HECKTHEUER, Luisa Helena Rychecki
dc.subject.por.fl_str_mv Alpha-linolenic acid
Flax
Rats
Ácido alfa-linolênico
Linho
Ratos
topic Alpha-linolenic acid
Flax
Rats
Ácido alfa-linolênico
Linho
Ratos
description ObjectiveThe objective of this investigation was to evaluate the effects of flaxseed (Linum usitatissimum L.) prepared by different methods on the biological response of rats.MethodsWeaned rats (n=32) were divided into 4 groups of 8 animals each: standard feed, standard feed with 16% raw flaxseed, standard feed with 16% roasted flaxseed and standard feed with 7% flaxseed oil. The animals were weighted at every 3 days and after 23 days, rats were killed by heart puncture. The organs were immediately weighed and the blood was collected and stored at -18ºC for biochemical assays (blood glucose, total cholesterol, High density lipoprotein cholesterol, triglyceride and total protein). The feces were collected for analysis of moisture, excreted lipids and absorbed lipids.ResultsThe groups did not differ with respect to weight gain, daily food intake, food efficiency ratio and organ weight. Daily excretion, feces moisture and fecal lipid content were greater in the groups fed raw and roasted flaxseed than in the groups fed standard feed and flaxseed oil. Except for high density lipoprotein-cholesterol, all other biochemical parameters presented statistical differences between treatments.ConclusionRaw or roasted flaxseed or flaxseed oil has biological activity in rats: it reduces blood glucose, triglyceride and cholesterol levels. Furthermore, rats fed raw and roasted flaxseed presented a significantly greater fecal volume and fecal lipid content
publishDate 2023
dc.date.none.fl_str_mv 2023-08-23
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.puc-campinas.edu.br/nutricao/article/view/9292
url https://periodicos.puc-campinas.edu.br/nutricao/article/view/9292
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://periodicos.puc-campinas.edu.br/nutricao/article/view/9292/6669
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Núcleo de Editoração – PUC-Campinas
publisher.none.fl_str_mv Núcleo de Editoração – PUC-Campinas
dc.source.none.fl_str_mv Brazilian Journal of Nutrition; Vol. 24 No. 1 (2011): Revista de Nutrição
Revista de Nutrição; Vol. 24 Núm. 1 (2011): Revista de Nutrição
Revista de Nutrição; v. 24 n. 1 (2011): Revista de Nutrição
1678-9865
reponame:Revista de Nutrição
instname:Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS)
instacron:PUC_CAMP
instname_str Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS)
instacron_str PUC_CAMP
institution PUC_CAMP
reponame_str Revista de Nutrição
collection Revista de Nutrição
repository.name.fl_str_mv Revista de Nutrição - Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS)
repository.mail.fl_str_mv ||sbi.submissionrn@puc-campinas.edu.br
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