Conjugated linoleic acid and weight loss

Detalhes bibliográficos
Autor(a) principal: Machado Mourão, Denise
Data de Publicação: 2023
Outros Autores: Bressan Resende MONTEIRO, Josefina, Brunoro COSTA, Neuza Maria, STRINGHETA, Paulo César, Rodrigues MINIM, Valéria Paula, Ganns Chaves DIAS, Cristina Maria
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista de Nutrição
Texto Completo: https://periodicos.puc-campinas.edu.br/nutricao/article/view/9840
Resumo: The prevention and the treatment of obesity have proved to be enormous challenges for health professionals. On their turn, the food and the pharmaceutical industries have been offering an increasingly vast array of new products which are said to promote weight loss. The conjugated linoleic acid, found in greater concentrations in the fat of ruminant mammals, seems to present favorable effects on body weight maintenance. This work reviewed the available data in the literature that related conjugated linoleic acid to energy expenditure and body composition, with the objective of better understanding its real or possible actions in the body, in particular, whether I does or does not promote weight loss. The studies on humans are not conclusive yet, although some of them have suggested an increase of lipolysis, and/or decrease of lipogenesis, which are reflected only on body composition changes, especially on the abdominal adipose tissue, but not on body weight loss. Furthermore, the high doses of conjugated linoleic acid used in these studies may produce undesirable collateral effects. Thus, more studies are necessary before this fat acid can be recommended as an agent to improve body composition and/or as an anti-obesity agent.
id PUC_CAMP-2_d1777a0e548313b187f232756eeb01e0
oai_identifier_str oai:ojs.periodicos.puc-campinas.edu.br:article/9840
network_acronym_str PUC_CAMP-2
network_name_str Revista de Nutrição
repository_id_str
spelling Conjugated linoleic acid and weight lossÁcido linoléico conjugado e perda de pesolinoleic acidbody compositionobesityweight lossácido linoléicocomposição corporalobesidadeperda de pesoThe prevention and the treatment of obesity have proved to be enormous challenges for health professionals. On their turn, the food and the pharmaceutical industries have been offering an increasingly vast array of new products which are said to promote weight loss. The conjugated linoleic acid, found in greater concentrations in the fat of ruminant mammals, seems to present favorable effects on body weight maintenance. This work reviewed the available data in the literature that related conjugated linoleic acid to energy expenditure and body composition, with the objective of better understanding its real or possible actions in the body, in particular, whether I does or does not promote weight loss. The studies on humans are not conclusive yet, although some of them have suggested an increase of lipolysis, and/or decrease of lipogenesis, which are reflected only on body composition changes, especially on the abdominal adipose tissue, but not on body weight loss. Furthermore, the high doses of conjugated linoleic acid used in these studies may produce undesirable collateral effects. Thus, more studies are necessary before this fat acid can be recommended as an agent to improve body composition and/or as an anti-obesity agent.O tratamento e a prevenção da obesidade têm sido considerados uma enorme batalha para os profissionais da área de saúde. As indústrias de alimentos e de fármacos, por sua vez, têm oferecido cada vez mais uma vasta gama de novos produtos que preconizam a perda de peso. O ácido linoléico conjugado, encontrado em maiores concentrações na gordura de animais ruminantes, parece apresentar efeitos favoráveis quanto à manutenção do peso corporal. Esta revisão apresenta uma análise crítica dos dados disponíveis na literatura, que relacionam o ácido linoléico conjugado com o metabolismo energético e a composição corporal. Os estudos realizados com humanos ainda não são conclusivos, embora alguns apontem um possível aumento da lipólise e/ou redução da lipogênese, que reflete em alterações apenas na composição corporal, especialmente no tecido adiposo abdominal, mas não na perda de peso. Entretanto, as altas doses usadas nesses estudos podem implicar efeitos colaterais indesejáveis. Portanto, mais estudos são necessários para uma indicação desse ácido graxo como um agente para a melhora da composição corporal e/ou como um agente antiobesidade. Núcleo de Editoração – PUC-Campinas2023-09-22info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://periodicos.puc-campinas.edu.br/nutricao/article/view/9840Brazilian Journal of Nutrition; Vol. 18 No. 3 (2005): Revista de NutriçãoRevista de Nutrição; Vol. 18 Núm. 3 (2005): Revista de NutriçãoRevista de Nutrição; v. 18 n. 3 (2005): Revista de Nutrição1678-9865reponame:Revista de Nutriçãoinstname:Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS)instacron:PUC_CAMPporhttps://periodicos.puc-campinas.edu.br/nutricao/article/view/9840/7179Copyright (c) 2023 Denise Machado Mourão, Josefina Bressan Resende MONTEIRO, Neuza Maria Brunoro COSTA, Paulo César STRINGHETA, Valéria Paula Rodrigues MINIM, Cristina Maria Ganns Chaves DIAShttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessMachado Mourão, Denise Bressan Resende MONTEIRO, Josefina Brunoro COSTA, Neuza MariaSTRINGHETA, Paulo César Rodrigues MINIM, Valéria Paula Ganns Chaves DIAS, Cristina Maria2023-09-22T11:11:42Zoai:ojs.periodicos.puc-campinas.edu.br:article/9840Revistahttp://www.scielo.br/rnPRIhttps://periodicos.puc-campinas.edu.br/nutricao/oai||sbi.submissionrn@puc-campinas.edu.br1678-98651415-5273opendoar:2023-09-22T11:11:42Revista de Nutrição - Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS)false
dc.title.none.fl_str_mv Conjugated linoleic acid and weight loss
Ácido linoléico conjugado e perda de peso
title Conjugated linoleic acid and weight loss
spellingShingle Conjugated linoleic acid and weight loss
Machado Mourão, Denise
linoleic acid
body composition
obesity
weight loss
ácido linoléico
composição corporal
obesidade
perda de peso
title_short Conjugated linoleic acid and weight loss
title_full Conjugated linoleic acid and weight loss
title_fullStr Conjugated linoleic acid and weight loss
title_full_unstemmed Conjugated linoleic acid and weight loss
title_sort Conjugated linoleic acid and weight loss
author Machado Mourão, Denise
author_facet Machado Mourão, Denise
Bressan Resende MONTEIRO, Josefina
Brunoro COSTA, Neuza Maria
STRINGHETA, Paulo César
Rodrigues MINIM, Valéria Paula
Ganns Chaves DIAS, Cristina Maria
author_role author
author2 Bressan Resende MONTEIRO, Josefina
Brunoro COSTA, Neuza Maria
STRINGHETA, Paulo César
Rodrigues MINIM, Valéria Paula
Ganns Chaves DIAS, Cristina Maria
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Machado Mourão, Denise
Bressan Resende MONTEIRO, Josefina
Brunoro COSTA, Neuza Maria
STRINGHETA, Paulo César
Rodrigues MINIM, Valéria Paula
Ganns Chaves DIAS, Cristina Maria
dc.subject.por.fl_str_mv linoleic acid
body composition
obesity
weight loss
ácido linoléico
composição corporal
obesidade
perda de peso
topic linoleic acid
body composition
obesity
weight loss
ácido linoléico
composição corporal
obesidade
perda de peso
description The prevention and the treatment of obesity have proved to be enormous challenges for health professionals. On their turn, the food and the pharmaceutical industries have been offering an increasingly vast array of new products which are said to promote weight loss. The conjugated linoleic acid, found in greater concentrations in the fat of ruminant mammals, seems to present favorable effects on body weight maintenance. This work reviewed the available data in the literature that related conjugated linoleic acid to energy expenditure and body composition, with the objective of better understanding its real or possible actions in the body, in particular, whether I does or does not promote weight loss. The studies on humans are not conclusive yet, although some of them have suggested an increase of lipolysis, and/or decrease of lipogenesis, which are reflected only on body composition changes, especially on the abdominal adipose tissue, but not on body weight loss. Furthermore, the high doses of conjugated linoleic acid used in these studies may produce undesirable collateral effects. Thus, more studies are necessary before this fat acid can be recommended as an agent to improve body composition and/or as an anti-obesity agent.
publishDate 2023
dc.date.none.fl_str_mv 2023-09-22
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.puc-campinas.edu.br/nutricao/article/view/9840
url https://periodicos.puc-campinas.edu.br/nutricao/article/view/9840
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://periodicos.puc-campinas.edu.br/nutricao/article/view/9840/7179
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Núcleo de Editoração – PUC-Campinas
publisher.none.fl_str_mv Núcleo de Editoração – PUC-Campinas
dc.source.none.fl_str_mv Brazilian Journal of Nutrition; Vol. 18 No. 3 (2005): Revista de Nutrição
Revista de Nutrição; Vol. 18 Núm. 3 (2005): Revista de Nutrição
Revista de Nutrição; v. 18 n. 3 (2005): Revista de Nutrição
1678-9865
reponame:Revista de Nutrição
instname:Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS)
instacron:PUC_CAMP
instname_str Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS)
instacron_str PUC_CAMP
institution PUC_CAMP
reponame_str Revista de Nutrição
collection Revista de Nutrição
repository.name.fl_str_mv Revista de Nutrição - Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS)
repository.mail.fl_str_mv ||sbi.submissionrn@puc-campinas.edu.br
_version_ 1799126075704344576