The relationship between nasopharyngeal tonsil size and laboratory markers in children infected with HIV
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista odonto ciência (Online) |
Texto Completo: | https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/6532 |
Resumo: | Purpose: The enlargement of nasopharyngeal tonsils, which leads to nasal obstruction and subsequent mouth breathing, can be caused by the presence of HIV. The aim of this research was to study nasopharyngeal tonsil sizes in HIV-infected children ranging from 6 to 13 years and to relate these findings to CD4+ T-cell counts and viral loads. Methods: Sixty children with HIV (mean age: 9 years and 8 months), infected by vertical transmission, had the sizes of their nasopharynx measured using lateral cephalometric radiographs, specifically focusing on the anatomical areas occupied by the nasopharyngeal tonsils. The children’s medical records were analyzed to assess information about TCD4+ lymphocyte count (%) and viral loads (log10). Results: The mean value for the nasopharyngeal tonsil size percentage was 70.37%±14.07%. All of the children showed moderate or accentuated hypertrophy of nasopharyngeal tonsils. The average percentage of CD4+ T-cells among the 60 HIV-infected children was 35.01%±10.76%, whereas the mean value for the viral load was 3.35±1.08 log10. Conclusion: There was no association between the size percentages of the nasopharyngeal tonsils (calculated against overall nasopharynx sizes) and CD4+ T-cell percentage (r=-0.0136; P=0.298) or the viral load log10 (r=-0.033; P=0.805). |
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The relationship between nasopharyngeal tonsil size and laboratory markers in children infected with HIVRelação entre tamanho da tonsila faríngea e marcadores laboratoriais em crianças infectadas por HIVHIVpediatric AIDSadenoidslateral cephalometric radiographOral MedicineHIVAIDS pediátricaadenóideradiografia cefalométrica lateralEstomatologiaradiologiaPurpose: The enlargement of nasopharyngeal tonsils, which leads to nasal obstruction and subsequent mouth breathing, can be caused by the presence of HIV. The aim of this research was to study nasopharyngeal tonsil sizes in HIV-infected children ranging from 6 to 13 years and to relate these findings to CD4+ T-cell counts and viral loads. Methods: Sixty children with HIV (mean age: 9 years and 8 months), infected by vertical transmission, had the sizes of their nasopharynx measured using lateral cephalometric radiographs, specifically focusing on the anatomical areas occupied by the nasopharyngeal tonsils. The children’s medical records were analyzed to assess information about TCD4+ lymphocyte count (%) and viral loads (log10). Results: The mean value for the nasopharyngeal tonsil size percentage was 70.37%±14.07%. All of the children showed moderate or accentuated hypertrophy of nasopharyngeal tonsils. The average percentage of CD4+ T-cells among the 60 HIV-infected children was 35.01%±10.76%, whereas the mean value for the viral load was 3.35±1.08 log10. Conclusion: There was no association between the size percentages of the nasopharyngeal tonsils (calculated against overall nasopharynx sizes) and CD4+ T-cell percentage (r=-0.0136; P=0.298) or the viral load log10 (r=-0.033; P=0.805).Objetivo: A presença do HIV na tonsila faríngea pode causar seu aumento de volume, ocasionando obstrução nasal e, consequentemente, respiração bucal. O objetivo deste trabalho foi avaliar o tamanho da tonsila faríngea em crianças infectadas pelo HIV por transmissão vertical, de 6 a 13 anos de idade, relacionando-a com a contagem de células T-CD4+ e carga viral (log10). Metodologia: Sessenta crianças HIV positivo (idade média: 9 anos e 8 meses), infectadas por transmissão vertical, tiveram o tamanho da tonsila faríngea mensurado na radiografia cefalométrica lateral da face. Os prontuários das crianças foram analisados para buscar os dados de contagem de linfócitos T-CD4+ (%) e carga viral (log10). Resultados: A média do tamanho da tonsila faríngea foi de 70,37%±14,07%. As crianças apresentaram hipertrofia da tonsila faríngea considerada moderada ou acentuada. A porcentagem média de linfócitos T-CD4+ nas 60 crianças foi de 35,01%±10,76% e a média da carga viral foi de 3,35±1,08 log10. Conclusão: Não foi comprovada relação entre o tamanho da tonsila faríngea com a porcentagem de linfócitos T-CD4+ (r=-0,0136; P=0,298) e com a carga viral (r=-0,033; P=0,805).EDIPUCRS - Editora Universitária da PUCRS2010-06-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed Articlecross-sectionaltransversalapplication/pdfhttps://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/6532Revista Odonto Ciência; Vol. 25 No. 3 (2010); 230 - 233Revista Odonto Ciência; v. 25 n. 3 (2010); 230 - 2331980-65230102-9460reponame:Revista odonto ciência (Online)instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)instacron:PUC_RSenghttps://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/6532/5612Zastrow, Michella DinahGrando, Liliane Janetede Carvalho, Aroldo Prohmannda Silva Rath, Inês BeatrizCalvo, Maria Cristinainfo:eu-repo/semantics/openAccess2013-11-11T12:30:18Zoai:ojs.revistaseletronicas.pucrs.br:article/6532Revistahttps://revistaseletronicas.pucrs.br/ojs/index.php/foPRIhttps://revistaseletronicas.pucrs.br/ojs/index.php/fo/oai||odontociencia@pucrs.br1980-65230102-9460opendoar:2013-11-11T12:30:18Revista odonto ciência (Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)false |
dc.title.none.fl_str_mv |
The relationship between nasopharyngeal tonsil size and laboratory markers in children infected with HIV Relação entre tamanho da tonsila faríngea e marcadores laboratoriais em crianças infectadas por HIV |
title |
The relationship between nasopharyngeal tonsil size and laboratory markers in children infected with HIV |
spellingShingle |
The relationship between nasopharyngeal tonsil size and laboratory markers in children infected with HIV Zastrow, Michella Dinah HIV pediatric AIDS adenoids lateral cephalometric radiograph Oral Medicine HIV AIDS pediátrica adenóide radiografia cefalométrica lateral Estomatologia radiologia |
title_short |
The relationship between nasopharyngeal tonsil size and laboratory markers in children infected with HIV |
title_full |
The relationship between nasopharyngeal tonsil size and laboratory markers in children infected with HIV |
title_fullStr |
The relationship between nasopharyngeal tonsil size and laboratory markers in children infected with HIV |
title_full_unstemmed |
The relationship between nasopharyngeal tonsil size and laboratory markers in children infected with HIV |
title_sort |
The relationship between nasopharyngeal tonsil size and laboratory markers in children infected with HIV |
author |
Zastrow, Michella Dinah |
author_facet |
Zastrow, Michella Dinah Grando, Liliane Janete de Carvalho, Aroldo Prohmann da Silva Rath, Inês Beatriz Calvo, Maria Cristina |
author_role |
author |
author2 |
Grando, Liliane Janete de Carvalho, Aroldo Prohmann da Silva Rath, Inês Beatriz Calvo, Maria Cristina |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Zastrow, Michella Dinah Grando, Liliane Janete de Carvalho, Aroldo Prohmann da Silva Rath, Inês Beatriz Calvo, Maria Cristina |
dc.subject.por.fl_str_mv |
HIV pediatric AIDS adenoids lateral cephalometric radiograph Oral Medicine HIV AIDS pediátrica adenóide radiografia cefalométrica lateral Estomatologia radiologia |
topic |
HIV pediatric AIDS adenoids lateral cephalometric radiograph Oral Medicine HIV AIDS pediátrica adenóide radiografia cefalométrica lateral Estomatologia radiologia |
description |
Purpose: The enlargement of nasopharyngeal tonsils, which leads to nasal obstruction and subsequent mouth breathing, can be caused by the presence of HIV. The aim of this research was to study nasopharyngeal tonsil sizes in HIV-infected children ranging from 6 to 13 years and to relate these findings to CD4+ T-cell counts and viral loads. Methods: Sixty children with HIV (mean age: 9 years and 8 months), infected by vertical transmission, had the sizes of their nasopharynx measured using lateral cephalometric radiographs, specifically focusing on the anatomical areas occupied by the nasopharyngeal tonsils. The children’s medical records were analyzed to assess information about TCD4+ lymphocyte count (%) and viral loads (log10). Results: The mean value for the nasopharyngeal tonsil size percentage was 70.37%±14.07%. All of the children showed moderate or accentuated hypertrophy of nasopharyngeal tonsils. The average percentage of CD4+ T-cells among the 60 HIV-infected children was 35.01%±10.76%, whereas the mean value for the viral load was 3.35±1.08 log10. Conclusion: There was no association between the size percentages of the nasopharyngeal tonsils (calculated against overall nasopharynx sizes) and CD4+ T-cell percentage (r=-0.0136; P=0.298) or the viral load log10 (r=-0.033; P=0.805). |
publishDate |
2010 |
dc.date.none.fl_str_mv |
2010-06-11 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article cross-sectional transversal |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/6532 |
url |
https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/6532 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/6532/5612 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
EDIPUCRS - Editora Universitária da PUCRS |
publisher.none.fl_str_mv |
EDIPUCRS - Editora Universitária da PUCRS |
dc.source.none.fl_str_mv |
Revista Odonto Ciência; Vol. 25 No. 3 (2010); 230 - 233 Revista Odonto Ciência; v. 25 n. 3 (2010); 230 - 233 1980-6523 0102-9460 reponame:Revista odonto ciência (Online) instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) instacron:PUC_RS |
instname_str |
Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) |
instacron_str |
PUC_RS |
institution |
PUC_RS |
reponame_str |
Revista odonto ciência (Online) |
collection |
Revista odonto ciência (Online) |
repository.name.fl_str_mv |
Revista odonto ciência (Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) |
repository.mail.fl_str_mv |
||odontociencia@pucrs.br |
_version_ |
1754820875353325568 |