The relationship between nasopharyngeal tonsil size and laboratory markers in children infected with HIV

Detalhes bibliográficos
Autor(a) principal: Zastrow, Michella Dinah
Data de Publicação: 2010
Outros Autores: Grando, Liliane Janete, de Carvalho, Aroldo Prohmann, da Silva Rath, Inês Beatriz, Calvo, Maria Cristina
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista odonto ciência (Online)
Texto Completo: https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/6532
Resumo: Purpose: The enlargement of nasopharyngeal tonsils, which leads to nasal obstruction and subsequent mouth breathing, can be caused by the presence of HIV. The aim of this research was to study nasopharyngeal tonsil sizes in HIV-infected children ranging from 6 to 13 years and to relate these findings to CD4+ T-cell counts and viral loads. Methods: Sixty children with HIV (mean age: 9 years and 8 months), infected by vertical transmission, had the sizes of their nasopharynx measured using lateral cephalometric radiographs, specifically focusing on the anatomical areas occupied by the nasopharyngeal tonsils. The children’s medical records were analyzed to assess information about TCD4+ lymphocyte count (%) and viral loads (log10). Results: The mean value for the nasopharyngeal tonsil size percentage was 70.37%±14.07%. All of the children showed moderate or accentuated hypertrophy of nasopharyngeal tonsils. The average percentage of CD4+ T-cells among the 60 HIV-infected children was 35.01%±10.76%, whereas the mean value for the viral load was 3.35±1.08 log10. Conclusion: There was no association between the size percentages of the nasopharyngeal tonsils (calculated against overall nasopharynx sizes) and CD4+ T-cell percentage (r=-0.0136; P=0.298) or the viral load log10 (r=-0.033; P=0.805).
id PUC_RS-22_2e7a9bc5938a8549f5b08aea4c777812
oai_identifier_str oai:ojs.revistaseletronicas.pucrs.br:article/6532
network_acronym_str PUC_RS-22
network_name_str Revista odonto ciência (Online)
repository_id_str
spelling The relationship between nasopharyngeal tonsil size and laboratory markers in children infected with HIVRelação entre tamanho da tonsila faríngea e marcadores laboratoriais em crianças infectadas por HIVHIVpediatric AIDSadenoidslateral cephalometric radiographOral MedicineHIVAIDS pediátricaadenóideradiografia cefalométrica lateralEstomatologiaradiologiaPurpose: The enlargement of nasopharyngeal tonsils, which leads to nasal obstruction and subsequent mouth breathing, can be caused by the presence of HIV. The aim of this research was to study nasopharyngeal tonsil sizes in HIV-infected children ranging from 6 to 13 years and to relate these findings to CD4+ T-cell counts and viral loads. Methods: Sixty children with HIV (mean age: 9 years and 8 months), infected by vertical transmission, had the sizes of their nasopharynx measured using lateral cephalometric radiographs, specifically focusing on the anatomical areas occupied by the nasopharyngeal tonsils. The children’s medical records were analyzed to assess information about TCD4+ lymphocyte count (%) and viral loads (log10). Results: The mean value for the nasopharyngeal tonsil size percentage was 70.37%±14.07%. All of the children showed moderate or accentuated hypertrophy of nasopharyngeal tonsils. The average percentage of CD4+ T-cells among the 60 HIV-infected children was 35.01%±10.76%, whereas the mean value for the viral load was 3.35±1.08 log10. Conclusion: There was no association between the size percentages of the nasopharyngeal tonsils (calculated against overall nasopharynx sizes) and CD4+ T-cell percentage (r=-0.0136; P=0.298) or the viral load log10 (r=-0.033; P=0.805).Objetivo: A presença do HIV na tonsila faríngea pode causar seu aumento de volume, ocasionando obstrução nasal e, consequentemente, respiração bucal. O objetivo deste trabalho foi avaliar o tamanho da tonsila faríngea em crianças infectadas pelo HIV por transmissão vertical, de 6 a 13 anos de idade, relacionando-a com a contagem de células T-CD4+ e carga viral (log10). Metodologia: Sessenta crianças HIV positivo (idade média: 9 anos e 8 meses), infectadas por transmissão vertical, tiveram o tamanho da tonsila faríngea mensurado na radiografia cefalométrica lateral da face. Os prontuários das crianças foram analisados para buscar os dados de contagem de linfócitos T-CD4+ (%) e carga viral (log10). Resultados: A média do tamanho da tonsila faríngea foi de 70,37%±14,07%. As crianças apresentaram hipertrofia da tonsila faríngea considerada moderada ou acentuada. A porcentagem média de linfócitos T-CD4+ nas 60 crianças foi de 35,01%±10,76% e a média da carga viral foi de 3,35±1,08 log10. Conclusão: Não foi comprovada relação entre o tamanho da tonsila faríngea com a porcentagem de linfócitos T-CD4+ (r=-0,0136; P=0,298) e com a carga viral (r=-0,033; P=0,805).EDIPUCRS - Editora Universitária da PUCRS2010-06-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed Articlecross-sectionaltransversalapplication/pdfhttps://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/6532Revista Odonto Ciência; Vol. 25 No. 3 (2010); 230 - 233Revista Odonto Ciência; v. 25 n. 3 (2010); 230 - 2331980-65230102-9460reponame:Revista odonto ciência (Online)instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)instacron:PUC_RSenghttps://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/6532/5612Zastrow, Michella DinahGrando, Liliane Janetede Carvalho, Aroldo Prohmannda Silva Rath, Inês BeatrizCalvo, Maria Cristinainfo:eu-repo/semantics/openAccess2013-11-11T12:30:18Zoai:ojs.revistaseletronicas.pucrs.br:article/6532Revistahttps://revistaseletronicas.pucrs.br/ojs/index.php/foPRIhttps://revistaseletronicas.pucrs.br/ojs/index.php/fo/oai||odontociencia@pucrs.br1980-65230102-9460opendoar:2013-11-11T12:30:18Revista odonto ciência (Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)false
dc.title.none.fl_str_mv The relationship between nasopharyngeal tonsil size and laboratory markers in children infected with HIV
Relação entre tamanho da tonsila faríngea e marcadores laboratoriais em crianças infectadas por HIV
title The relationship between nasopharyngeal tonsil size and laboratory markers in children infected with HIV
spellingShingle The relationship between nasopharyngeal tonsil size and laboratory markers in children infected with HIV
Zastrow, Michella Dinah
HIV
pediatric AIDS
adenoids
lateral cephalometric radiograph
Oral Medicine
HIV
AIDS pediátrica
adenóide
radiografia cefalométrica lateral
Estomatologia
radiologia
title_short The relationship between nasopharyngeal tonsil size and laboratory markers in children infected with HIV
title_full The relationship between nasopharyngeal tonsil size and laboratory markers in children infected with HIV
title_fullStr The relationship between nasopharyngeal tonsil size and laboratory markers in children infected with HIV
title_full_unstemmed The relationship between nasopharyngeal tonsil size and laboratory markers in children infected with HIV
title_sort The relationship between nasopharyngeal tonsil size and laboratory markers in children infected with HIV
author Zastrow, Michella Dinah
author_facet Zastrow, Michella Dinah
Grando, Liliane Janete
de Carvalho, Aroldo Prohmann
da Silva Rath, Inês Beatriz
Calvo, Maria Cristina
author_role author
author2 Grando, Liliane Janete
de Carvalho, Aroldo Prohmann
da Silva Rath, Inês Beatriz
Calvo, Maria Cristina
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Zastrow, Michella Dinah
Grando, Liliane Janete
de Carvalho, Aroldo Prohmann
da Silva Rath, Inês Beatriz
Calvo, Maria Cristina
dc.subject.por.fl_str_mv HIV
pediatric AIDS
adenoids
lateral cephalometric radiograph
Oral Medicine
HIV
AIDS pediátrica
adenóide
radiografia cefalométrica lateral
Estomatologia
radiologia
topic HIV
pediatric AIDS
adenoids
lateral cephalometric radiograph
Oral Medicine
HIV
AIDS pediátrica
adenóide
radiografia cefalométrica lateral
Estomatologia
radiologia
description Purpose: The enlargement of nasopharyngeal tonsils, which leads to nasal obstruction and subsequent mouth breathing, can be caused by the presence of HIV. The aim of this research was to study nasopharyngeal tonsil sizes in HIV-infected children ranging from 6 to 13 years and to relate these findings to CD4+ T-cell counts and viral loads. Methods: Sixty children with HIV (mean age: 9 years and 8 months), infected by vertical transmission, had the sizes of their nasopharynx measured using lateral cephalometric radiographs, specifically focusing on the anatomical areas occupied by the nasopharyngeal tonsils. The children’s medical records were analyzed to assess information about TCD4+ lymphocyte count (%) and viral loads (log10). Results: The mean value for the nasopharyngeal tonsil size percentage was 70.37%±14.07%. All of the children showed moderate or accentuated hypertrophy of nasopharyngeal tonsils. The average percentage of CD4+ T-cells among the 60 HIV-infected children was 35.01%±10.76%, whereas the mean value for the viral load was 3.35±1.08 log10. Conclusion: There was no association between the size percentages of the nasopharyngeal tonsils (calculated against overall nasopharynx sizes) and CD4+ T-cell percentage (r=-0.0136; P=0.298) or the viral load log10 (r=-0.033; P=0.805).
publishDate 2010
dc.date.none.fl_str_mv 2010-06-11
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
cross-sectional
transversal
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/6532
url https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/6532
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/6532/5612
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv EDIPUCRS - Editora Universitária da PUCRS
publisher.none.fl_str_mv EDIPUCRS - Editora Universitária da PUCRS
dc.source.none.fl_str_mv Revista Odonto Ciência; Vol. 25 No. 3 (2010); 230 - 233
Revista Odonto Ciência; v. 25 n. 3 (2010); 230 - 233
1980-6523
0102-9460
reponame:Revista odonto ciência (Online)
instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron:PUC_RS
instname_str Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron_str PUC_RS
institution PUC_RS
reponame_str Revista odonto ciência (Online)
collection Revista odonto ciência (Online)
repository.name.fl_str_mv Revista odonto ciência (Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
repository.mail.fl_str_mv ||odontociencia@pucrs.br
_version_ 1754820875353325568