Historical evolution of the surgical treatment of pancreatic cancer

Detalhes bibliográficos
Autor(a) principal: Toneto, Marcelo Garcia
Data de Publicação: 2014
Outros Autores: Lopes, Maria Helena Itaqui
Tipo de documento: Artigo
Idioma: eng
por
Título da fonte: Scientia Medica (Porto Alegre. Online)
Texto Completo: https://revistaseletronicas.pucrs.br/scientiamedica/article/view/17647
Resumo: AIMS: To review the main historical aspects of the evolution of the treatment of pancreatic cancer. SOURCE OF DATA: Literature review through PubMed. Selected articles on the history of the treatment of pancreatic cancer were analyzed. SUMMARY OF FINDINGS: Complete surgical resection is the only therapeutic alternative that may allow cure of patients with pancreatic cancer. However, pancreaticoduodenectomy is one of the most challenging surgical procedures, requiring surgeons with a high level of training for its secure implementation. Several protagonists were involved in the evolution of the surgical technique in pancreatic surgery until the procedure reached current levels of security. CONCLUSIONS: Despite the safety with which pancreaticoduodenectomy is currently performed, postoperative survival in pancreatic cancer is still insufficient, suggesting that technical issues are just one of the steps needed to improve outcome. Better screening methods to diagnose earlier tumors, identification of high risk patients and improvement in adjuvant treatment are needed to increase the cure rate of this neoplasm.
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spelling Historical evolution of the surgical treatment of pancreatic cancerEvolução histórica do tratamento cirúrgico do câncer de pâncreasCANCER OF PANCREASPANCREATICODUODENECTOMYHISTORY OF MEDICINESURGERYCÂNCER DO PÂNCREASDUODENOPANCREATECTOMIAHISTÓRIA DA MEDICINACIRURGIAMedicinaCirurgiaHistória da MedicinaAIMS: To review the main historical aspects of the evolution of the treatment of pancreatic cancer. SOURCE OF DATA: Literature review through PubMed. Selected articles on the history of the treatment of pancreatic cancer were analyzed. SUMMARY OF FINDINGS: Complete surgical resection is the only therapeutic alternative that may allow cure of patients with pancreatic cancer. However, pancreaticoduodenectomy is one of the most challenging surgical procedures, requiring surgeons with a high level of training for its secure implementation. Several protagonists were involved in the evolution of the surgical technique in pancreatic surgery until the procedure reached current levels of security. CONCLUSIONS: Despite the safety with which pancreaticoduodenectomy is currently performed, postoperative survival in pancreatic cancer is still insufficient, suggesting that technical issues are just one of the steps needed to improve outcome. Better screening methods to diagnose earlier tumors, identification of high risk patients and improvement in adjuvant treatment are needed to increase the cure rate of this neoplasm.OBJETIVOS: Revisar os principais aspectos históricos da evolução do tratamento do câncer de pâncreas. FONTE DE DADOS: Revisão bibliográfica através do PubMed. Foram analisados artigos selecionados sobre a história do tratamento do câncer de pâncreas. SÍNTESE DOS DADOS: Ressecção cirúrgica completa é a única alternativa terapêutica que pode possibilitar a cura dos pacientes com câncer de pâncreas. Entretanto, a duodenopancreatectomia é um dos procedimentos cirúrgicos mais desafiadores, necessitando cirurgiões com alto nível de treinamento para sua execução com segurança. Diversos personagens estiveram envolvidos na evolução da técnica operatória na cirurgia pancreática até que o procedimento atingisse os níveis de segurança atuais. CONCLUSÕES: Apesar da segurança com a qual a duodenopancreatectomia é realizada atualmente, a sobrevida pós-operatória no câncer de pâncreas ainda é insuficiente, sugerindo que as questões técnicas operatórias representam apenas uma das etapas necessárias para progresso dos resultados. Melhora no sistema de rastreamento, diagnosticando tumores mais precoces, identificação de pacientes de alto risco e aperfeiçoamento no tratamento adjuvante são necessários para aumentar a taxa de cura dessa neoplasia.Editora da PUCRS - ediPUCRS2014-06-24info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://revistaseletronicas.pucrs.br/scientiamedica/article/view/1764710.15448/1980-6108.2014.2.17647Scientia Medica; Vol. 24 No. 2 (2014); 193-201Scientia Medica; v. 24 n. 2 (2014); 193-2011980-61081806-556210.15448/1980-6108.2014.2reponame:Scientia Medica (Porto Alegre. Online)instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)instacron:PUC_RSengporhttps://revistaseletronicas.pucrs.br/scientiamedica/article/view/17647/13324https://revistaseletronicas.pucrs.br/scientiamedica/article/view/17647/11508Toneto, Marcelo GarciaLopes, Maria Helena Itaquiinfo:eu-repo/semantics/openAccess2017-08-28T14:51:17Zoai:ojs.revistaseletronicas.pucrs.br:article/17647Revistahttps://revistaseletronicas.pucrs.br/scientiamedica/PUBhttps://revistaseletronicas.pucrs.br/scientiamedica/oaiscientiamedica@pucrs.br || editora.periodicos@pucrs.br1980-61081806-5562opendoar:2017-08-28T14:51:17Scientia Medica (Porto Alegre. Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)false
dc.title.none.fl_str_mv Historical evolution of the surgical treatment of pancreatic cancer
Evolução histórica do tratamento cirúrgico do câncer de pâncreas
title Historical evolution of the surgical treatment of pancreatic cancer
spellingShingle Historical evolution of the surgical treatment of pancreatic cancer
Toneto, Marcelo Garcia
CANCER OF PANCREAS
PANCREATICODUODENECTOMY
HISTORY OF MEDICINE
SURGERY
CÂNCER DO PÂNCREAS
DUODENOPANCREATECTOMIA
HISTÓRIA DA MEDICINA
CIRURGIA
Medicina
Cirurgia
História da Medicina
title_short Historical evolution of the surgical treatment of pancreatic cancer
title_full Historical evolution of the surgical treatment of pancreatic cancer
title_fullStr Historical evolution of the surgical treatment of pancreatic cancer
title_full_unstemmed Historical evolution of the surgical treatment of pancreatic cancer
title_sort Historical evolution of the surgical treatment of pancreatic cancer
author Toneto, Marcelo Garcia
author_facet Toneto, Marcelo Garcia
Lopes, Maria Helena Itaqui
author_role author
author2 Lopes, Maria Helena Itaqui
author2_role author
dc.contributor.author.fl_str_mv Toneto, Marcelo Garcia
Lopes, Maria Helena Itaqui
dc.subject.por.fl_str_mv CANCER OF PANCREAS
PANCREATICODUODENECTOMY
HISTORY OF MEDICINE
SURGERY
CÂNCER DO PÂNCREAS
DUODENOPANCREATECTOMIA
HISTÓRIA DA MEDICINA
CIRURGIA
Medicina
Cirurgia
História da Medicina
topic CANCER OF PANCREAS
PANCREATICODUODENECTOMY
HISTORY OF MEDICINE
SURGERY
CÂNCER DO PÂNCREAS
DUODENOPANCREATECTOMIA
HISTÓRIA DA MEDICINA
CIRURGIA
Medicina
Cirurgia
História da Medicina
description AIMS: To review the main historical aspects of the evolution of the treatment of pancreatic cancer. SOURCE OF DATA: Literature review through PubMed. Selected articles on the history of the treatment of pancreatic cancer were analyzed. SUMMARY OF FINDINGS: Complete surgical resection is the only therapeutic alternative that may allow cure of patients with pancreatic cancer. However, pancreaticoduodenectomy is one of the most challenging surgical procedures, requiring surgeons with a high level of training for its secure implementation. Several protagonists were involved in the evolution of the surgical technique in pancreatic surgery until the procedure reached current levels of security. CONCLUSIONS: Despite the safety with which pancreaticoduodenectomy is currently performed, postoperative survival in pancreatic cancer is still insufficient, suggesting that technical issues are just one of the steps needed to improve outcome. Better screening methods to diagnose earlier tumors, identification of high risk patients and improvement in adjuvant treatment are needed to increase the cure rate of this neoplasm.
publishDate 2014
dc.date.none.fl_str_mv 2014-06-24
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://revistaseletronicas.pucrs.br/scientiamedica/article/view/17647
10.15448/1980-6108.2014.2.17647
url https://revistaseletronicas.pucrs.br/scientiamedica/article/view/17647
identifier_str_mv 10.15448/1980-6108.2014.2.17647
dc.language.iso.fl_str_mv eng
por
language eng
por
dc.relation.none.fl_str_mv https://revistaseletronicas.pucrs.br/scientiamedica/article/view/17647/13324
https://revistaseletronicas.pucrs.br/scientiamedica/article/view/17647/11508
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Editora da PUCRS - ediPUCRS
publisher.none.fl_str_mv Editora da PUCRS - ediPUCRS
dc.source.none.fl_str_mv Scientia Medica; Vol. 24 No. 2 (2014); 193-201
Scientia Medica; v. 24 n. 2 (2014); 193-201
1980-6108
1806-5562
10.15448/1980-6108.2014.2
reponame:Scientia Medica (Porto Alegre. Online)
instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron:PUC_RS
instname_str Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron_str PUC_RS
institution PUC_RS
reponame_str Scientia Medica (Porto Alegre. Online)
collection Scientia Medica (Porto Alegre. Online)
repository.name.fl_str_mv Scientia Medica (Porto Alegre. Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
repository.mail.fl_str_mv scientiamedica@pucrs.br || editora.periodicos@pucrs.br
_version_ 1809101750580281344

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