Churg-Strauss Syndrome: case report [Abstract in English]

Detalhes bibliográficos
Autor(a) principal: Haggstram, Fabio Maraschin
Data de Publicação: 2008
Outros Autores: Zettler, Eduardo Walker, Braun, Cristiano
Tipo de documento: Artigo
Idioma: por
eng
Título da fonte: Scientia Medica (Porto Alegre. Online)
Texto Completo: https://revistaseletronicas.pucrs.br/scientiamedica/article/view/3736
Resumo: Aims: To describe a case of Churg-Strauss syndrome that was innitially diagnosed as difficult to treat asthma. Case description: The patient was a 46 years-old female, with a history of difficult to treat asthma since childhood (4 years-old), with frequent emergency room visits and hospitalizations due to asthma attack related to sinusitis and severe atopic disease. She presented with allergy to several medications, pulmonary function test with a moderate obstructive ventilatory disturbance and significant blood eosinophilia. Clinical and laboratory findings were suggestive of Churg-Strauss syndrome. Maxillary sinus mucosa biopsy with important eosinophilic infiltration corroborated the diagnosis. Conclusion: In spite of its low frequency, Churg-Strauss syndrome should be considered in the differential diagnosis of difficult to treat asthma, due to its poor prognosis and good response to treatment. KEY WORDS: CHURG-STRAUSS SYNDROME/diagnosis; ASTHMA/diagnosis; DIAGNOSIS, DIFFERENTIAL; CASE REPORTS.
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spelling Churg-Strauss Syndrome: case report [Abstract in English]Síndrome de Churg-Strauss: relato de casoSÍNDROME DE CHURG-STRAUSS/diagnósticoASMA/diagnósticoDIAGNÓSTICO DIFERENCIALRELATOS DE CASOS.Aims: To describe a case of Churg-Strauss syndrome that was innitially diagnosed as difficult to treat asthma. Case description: The patient was a 46 years-old female, with a history of difficult to treat asthma since childhood (4 years-old), with frequent emergency room visits and hospitalizations due to asthma attack related to sinusitis and severe atopic disease. She presented with allergy to several medications, pulmonary function test with a moderate obstructive ventilatory disturbance and significant blood eosinophilia. Clinical and laboratory findings were suggestive of Churg-Strauss syndrome. Maxillary sinus mucosa biopsy with important eosinophilic infiltration corroborated the diagnosis. Conclusion: In spite of its low frequency, Churg-Strauss syndrome should be considered in the differential diagnosis of difficult to treat asthma, due to its poor prognosis and good response to treatment. KEY WORDS: CHURG-STRAUSS SYNDROME/diagnosis; ASTHMA/diagnosis; DIAGNOSIS, DIFFERENTIAL; CASE REPORTS.Objetivos: descrever um caso de síndrome de Churg-Strauss em uma paciente que recebeu o diagnóstico inicial de asma de difícil controle. Descrição do caso: paciente feminina, 46 anos, apresentava história de asma de difícil controle iniciada ainda na infância, com quatro anos de idade, necessitando seguidamente recorrer às emergências hospitalares, com várias internações pelas crises asmáticas desencadeadas por sinusite e atopia grave. A paciente apresentava também história de alergia a várias medicações, teste de função pulmonar com distúrbio ventilatório obstrutivo moderado com resposta ao broncodilatador e eosinofilia periférica importante. Com base no quadro clínico e nos exames laboratoriais, levantou-se a suspeita de síndrome de Churg-Strauss. Foi então realizada biópsia da mucosa do seio maxilar, que evidenciou intenso infiltrado eosinofílico, corroborando o diagnóstico. Conclusão: apesar de infreqüente, a síndrome de Churg-Strauss deve sempre fazer parte do diagnóstico diferencial da asma de difícil controle, em razão do seu prognóstico desfavorável e da boa resposta ao tratamento. DESCRITORES: SÍNDROME DE CHURG-STRAUSS/diagnóstico; ASMA/diagnóstico; DIAGNÓSTICO DIFERENCIAL; RELATOS DE CASOS.Editora da PUCRS - ediPUCRS2008-12-15info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionRelato de caso raro ou de especial interesseapplication/pdfapplication/pdfhttps://revistaseletronicas.pucrs.br/scientiamedica/article/view/3736Scientia Medica; Vol. 18 No. 4 (2008); 172-176Scientia Medica; v. 18 n. 4 (2008); 172-1761980-61081806-5562reponame:Scientia Medica (Porto Alegre. Online)instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)instacron:PUC_RSporenghttps://revistaseletronicas.pucrs.br/scientiamedica/article/view/3736/3520https://revistaseletronicas.pucrs.br/scientiamedica/article/view/3736/7826Haggstram, Fabio MaraschinZettler, Eduardo WalkerBraun, Cristianoinfo:eu-repo/semantics/openAccess2013-07-17T13:15:54Zoai:ojs.revistaseletronicas.pucrs.br:article/3736Revistahttps://revistaseletronicas.pucrs.br/scientiamedica/PUBhttps://revistaseletronicas.pucrs.br/scientiamedica/oaiscientiamedica@pucrs.br || editora.periodicos@pucrs.br1980-61081806-5562opendoar:2013-07-17T13:15:54Scientia Medica (Porto Alegre. Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)false
dc.title.none.fl_str_mv Churg-Strauss Syndrome: case report [Abstract in English]
Síndrome de Churg-Strauss: relato de caso
title Churg-Strauss Syndrome: case report [Abstract in English]
spellingShingle Churg-Strauss Syndrome: case report [Abstract in English]
Haggstram, Fabio Maraschin
SÍNDROME DE CHURG-STRAUSS/diagnóstico
ASMA/diagnóstico
DIAGNÓSTICO DIFERENCIAL
RELATOS DE CASOS.
title_short Churg-Strauss Syndrome: case report [Abstract in English]
title_full Churg-Strauss Syndrome: case report [Abstract in English]
title_fullStr Churg-Strauss Syndrome: case report [Abstract in English]
title_full_unstemmed Churg-Strauss Syndrome: case report [Abstract in English]
title_sort Churg-Strauss Syndrome: case report [Abstract in English]
author Haggstram, Fabio Maraschin
author_facet Haggstram, Fabio Maraschin
Zettler, Eduardo Walker
Braun, Cristiano
author_role author
author2 Zettler, Eduardo Walker
Braun, Cristiano
author2_role author
author
dc.contributor.author.fl_str_mv Haggstram, Fabio Maraschin
Zettler, Eduardo Walker
Braun, Cristiano
dc.subject.por.fl_str_mv SÍNDROME DE CHURG-STRAUSS/diagnóstico
ASMA/diagnóstico
DIAGNÓSTICO DIFERENCIAL
RELATOS DE CASOS.
topic SÍNDROME DE CHURG-STRAUSS/diagnóstico
ASMA/diagnóstico
DIAGNÓSTICO DIFERENCIAL
RELATOS DE CASOS.
description Aims: To describe a case of Churg-Strauss syndrome that was innitially diagnosed as difficult to treat asthma. Case description: The patient was a 46 years-old female, with a history of difficult to treat asthma since childhood (4 years-old), with frequent emergency room visits and hospitalizations due to asthma attack related to sinusitis and severe atopic disease. She presented with allergy to several medications, pulmonary function test with a moderate obstructive ventilatory disturbance and significant blood eosinophilia. Clinical and laboratory findings were suggestive of Churg-Strauss syndrome. Maxillary sinus mucosa biopsy with important eosinophilic infiltration corroborated the diagnosis. Conclusion: In spite of its low frequency, Churg-Strauss syndrome should be considered in the differential diagnosis of difficult to treat asthma, due to its poor prognosis and good response to treatment. KEY WORDS: CHURG-STRAUSS SYNDROME/diagnosis; ASTHMA/diagnosis; DIAGNOSIS, DIFFERENTIAL; CASE REPORTS.
publishDate 2008
dc.date.none.fl_str_mv 2008-12-15
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Relato de caso raro ou de especial interesse
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://revistaseletronicas.pucrs.br/scientiamedica/article/view/3736
url https://revistaseletronicas.pucrs.br/scientiamedica/article/view/3736
dc.language.iso.fl_str_mv por
eng
language por
eng
dc.relation.none.fl_str_mv https://revistaseletronicas.pucrs.br/scientiamedica/article/view/3736/3520
https://revistaseletronicas.pucrs.br/scientiamedica/article/view/3736/7826
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Editora da PUCRS - ediPUCRS
publisher.none.fl_str_mv Editora da PUCRS - ediPUCRS
dc.source.none.fl_str_mv Scientia Medica; Vol. 18 No. 4 (2008); 172-176
Scientia Medica; v. 18 n. 4 (2008); 172-176
1980-6108
1806-5562
reponame:Scientia Medica (Porto Alegre. Online)
instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron:PUC_RS
instname_str Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron_str PUC_RS
institution PUC_RS
reponame_str Scientia Medica (Porto Alegre. Online)
collection Scientia Medica (Porto Alegre. Online)
repository.name.fl_str_mv Scientia Medica (Porto Alegre. Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
repository.mail.fl_str_mv scientiamedica@pucrs.br || editora.periodicos@pucrs.br
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