Churg-Strauss Syndrome: case report [Abstract in English]
Autor(a) principal: | |
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Data de Publicação: | 2008 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | por eng |
Título da fonte: | Scientia Medica (Porto Alegre. Online) |
Texto Completo: | https://revistaseletronicas.pucrs.br/scientiamedica/article/view/3736 |
Resumo: | Aims: To describe a case of Churg-Strauss syndrome that was innitially diagnosed as difficult to treat asthma. Case description: The patient was a 46 years-old female, with a history of difficult to treat asthma since childhood (4 years-old), with frequent emergency room visits and hospitalizations due to asthma attack related to sinusitis and severe atopic disease. She presented with allergy to several medications, pulmonary function test with a moderate obstructive ventilatory disturbance and significant blood eosinophilia. Clinical and laboratory findings were suggestive of Churg-Strauss syndrome. Maxillary sinus mucosa biopsy with important eosinophilic infiltration corroborated the diagnosis. Conclusion: In spite of its low frequency, Churg-Strauss syndrome should be considered in the differential diagnosis of difficult to treat asthma, due to its poor prognosis and good response to treatment. KEY WORDS: CHURG-STRAUSS SYNDROME/diagnosis; ASTHMA/diagnosis; DIAGNOSIS, DIFFERENTIAL; CASE REPORTS. |
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Scientia Medica (Porto Alegre. Online) |
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Churg-Strauss Syndrome: case report [Abstract in English]Síndrome de Churg-Strauss: relato de casoSÍNDROME DE CHURG-STRAUSS/diagnósticoASMA/diagnósticoDIAGNÓSTICO DIFERENCIALRELATOS DE CASOS.Aims: To describe a case of Churg-Strauss syndrome that was innitially diagnosed as difficult to treat asthma. Case description: The patient was a 46 years-old female, with a history of difficult to treat asthma since childhood (4 years-old), with frequent emergency room visits and hospitalizations due to asthma attack related to sinusitis and severe atopic disease. She presented with allergy to several medications, pulmonary function test with a moderate obstructive ventilatory disturbance and significant blood eosinophilia. Clinical and laboratory findings were suggestive of Churg-Strauss syndrome. Maxillary sinus mucosa biopsy with important eosinophilic infiltration corroborated the diagnosis. Conclusion: In spite of its low frequency, Churg-Strauss syndrome should be considered in the differential diagnosis of difficult to treat asthma, due to its poor prognosis and good response to treatment. KEY WORDS: CHURG-STRAUSS SYNDROME/diagnosis; ASTHMA/diagnosis; DIAGNOSIS, DIFFERENTIAL; CASE REPORTS.Objetivos: descrever um caso de síndrome de Churg-Strauss em uma paciente que recebeu o diagnóstico inicial de asma de difícil controle. Descrição do caso: paciente feminina, 46 anos, apresentava história de asma de difícil controle iniciada ainda na infância, com quatro anos de idade, necessitando seguidamente recorrer às emergências hospitalares, com várias internações pelas crises asmáticas desencadeadas por sinusite e atopia grave. A paciente apresentava também história de alergia a várias medicações, teste de função pulmonar com distúrbio ventilatório obstrutivo moderado com resposta ao broncodilatador e eosinofilia periférica importante. Com base no quadro clínico e nos exames laboratoriais, levantou-se a suspeita de síndrome de Churg-Strauss. Foi então realizada biópsia da mucosa do seio maxilar, que evidenciou intenso infiltrado eosinofílico, corroborando o diagnóstico. Conclusão: apesar de infreqüente, a síndrome de Churg-Strauss deve sempre fazer parte do diagnóstico diferencial da asma de difícil controle, em razão do seu prognóstico desfavorável e da boa resposta ao tratamento. DESCRITORES: SÍNDROME DE CHURG-STRAUSS/diagnóstico; ASMA/diagnóstico; DIAGNÓSTICO DIFERENCIAL; RELATOS DE CASOS.Editora da PUCRS - ediPUCRS2008-12-15info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionRelato de caso raro ou de especial interesseapplication/pdfapplication/pdfhttps://revistaseletronicas.pucrs.br/scientiamedica/article/view/3736Scientia Medica; Vol. 18 No. 4 (2008); 172-176Scientia Medica; v. 18 n. 4 (2008); 172-1761980-61081806-5562reponame:Scientia Medica (Porto Alegre. Online)instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)instacron:PUC_RSporenghttps://revistaseletronicas.pucrs.br/scientiamedica/article/view/3736/3520https://revistaseletronicas.pucrs.br/scientiamedica/article/view/3736/7826Haggstram, Fabio MaraschinZettler, Eduardo WalkerBraun, Cristianoinfo:eu-repo/semantics/openAccess2013-07-17T13:15:54Zoai:ojs.revistaseletronicas.pucrs.br:article/3736Revistahttps://revistaseletronicas.pucrs.br/scientiamedica/PUBhttps://revistaseletronicas.pucrs.br/scientiamedica/oaiscientiamedica@pucrs.br || editora.periodicos@pucrs.br1980-61081806-5562opendoar:2013-07-17T13:15:54Scientia Medica (Porto Alegre. Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)false |
dc.title.none.fl_str_mv |
Churg-Strauss Syndrome: case report [Abstract in English] Síndrome de Churg-Strauss: relato de caso |
title |
Churg-Strauss Syndrome: case report [Abstract in English] |
spellingShingle |
Churg-Strauss Syndrome: case report [Abstract in English] Haggstram, Fabio Maraschin SÍNDROME DE CHURG-STRAUSS/diagnóstico ASMA/diagnóstico DIAGNÓSTICO DIFERENCIAL RELATOS DE CASOS. |
title_short |
Churg-Strauss Syndrome: case report [Abstract in English] |
title_full |
Churg-Strauss Syndrome: case report [Abstract in English] |
title_fullStr |
Churg-Strauss Syndrome: case report [Abstract in English] |
title_full_unstemmed |
Churg-Strauss Syndrome: case report [Abstract in English] |
title_sort |
Churg-Strauss Syndrome: case report [Abstract in English] |
author |
Haggstram, Fabio Maraschin |
author_facet |
Haggstram, Fabio Maraschin Zettler, Eduardo Walker Braun, Cristiano |
author_role |
author |
author2 |
Zettler, Eduardo Walker Braun, Cristiano |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Haggstram, Fabio Maraschin Zettler, Eduardo Walker Braun, Cristiano |
dc.subject.por.fl_str_mv |
SÍNDROME DE CHURG-STRAUSS/diagnóstico ASMA/diagnóstico DIAGNÓSTICO DIFERENCIAL RELATOS DE CASOS. |
topic |
SÍNDROME DE CHURG-STRAUSS/diagnóstico ASMA/diagnóstico DIAGNÓSTICO DIFERENCIAL RELATOS DE CASOS. |
description |
Aims: To describe a case of Churg-Strauss syndrome that was innitially diagnosed as difficult to treat asthma. Case description: The patient was a 46 years-old female, with a history of difficult to treat asthma since childhood (4 years-old), with frequent emergency room visits and hospitalizations due to asthma attack related to sinusitis and severe atopic disease. She presented with allergy to several medications, pulmonary function test with a moderate obstructive ventilatory disturbance and significant blood eosinophilia. Clinical and laboratory findings were suggestive of Churg-Strauss syndrome. Maxillary sinus mucosa biopsy with important eosinophilic infiltration corroborated the diagnosis. Conclusion: In spite of its low frequency, Churg-Strauss syndrome should be considered in the differential diagnosis of difficult to treat asthma, due to its poor prognosis and good response to treatment. KEY WORDS: CHURG-STRAUSS SYNDROME/diagnosis; ASTHMA/diagnosis; DIAGNOSIS, DIFFERENTIAL; CASE REPORTS. |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008-12-15 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Relato de caso raro ou de especial interesse |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://revistaseletronicas.pucrs.br/scientiamedica/article/view/3736 |
url |
https://revistaseletronicas.pucrs.br/scientiamedica/article/view/3736 |
dc.language.iso.fl_str_mv |
por eng |
language |
por eng |
dc.relation.none.fl_str_mv |
https://revistaseletronicas.pucrs.br/scientiamedica/article/view/3736/3520 https://revistaseletronicas.pucrs.br/scientiamedica/article/view/3736/7826 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Editora da PUCRS - ediPUCRS |
publisher.none.fl_str_mv |
Editora da PUCRS - ediPUCRS |
dc.source.none.fl_str_mv |
Scientia Medica; Vol. 18 No. 4 (2008); 172-176 Scientia Medica; v. 18 n. 4 (2008); 172-176 1980-6108 1806-5562 reponame:Scientia Medica (Porto Alegre. Online) instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) instacron:PUC_RS |
instname_str |
Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) |
instacron_str |
PUC_RS |
institution |
PUC_RS |
reponame_str |
Scientia Medica (Porto Alegre. Online) |
collection |
Scientia Medica (Porto Alegre. Online) |
repository.name.fl_str_mv |
Scientia Medica (Porto Alegre. Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) |
repository.mail.fl_str_mv |
scientiamedica@pucrs.br || editora.periodicos@pucrs.br |
_version_ |
1809101748914094080 |