Effect of adjuvant antineoplastic treatment on body weight change in women with breast cancer
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por eng |
Título da fonte: | Scientia Medica (Porto Alegre. Online) |
Texto Completo: | https://revistaseletronicas.pucrs.br/scientiamedica/article/view/10738 |
Resumo: | AIMS: To identify the effect of adjuvant antineoplastic treatment on body weight change of women with breast cancer. METHODS: A non-randomized clinical study included women with a recent surgical diagnosis of breast cancer, admitted to the Maternidade Carmela Dutra hospital in Florianópolis, Santa Catarina, southern Brazil, between October 2006 and July 2008. Food intake, weight, body mass index, hip circumference, waist circumference and other variables were measured before (baseline) and after the adjuvant antineoplastic treatment (pos-treatment). A mixed effects linear regression model was used to estimate the longitudinal changes occurring in weight. RESULTS: The sample comprised 53 patients. A significant increase (P less than 0.05) was observed in body weight (2.81 kg), body mass index (1.08 kg/m2), hip circumference (3.62 cm) and waist circumference (1.93 cm). In relation to diet, there was a significant increase (P less than 0.05) in the intake of energy (272.7 kcal), total fat (11.2 g) and polyunsaturated fatty acids (5.4 g). The final regression model for the change in body weight demonstrated that the women who were exposed to chemotherapy treatment, and to chemotherapy associated with radiotherapy, had the largest mean increase in body weight (2.47 kg and 5.21 kg, respectively). Socio-economic, demographic and nutritional factors were not associated with the increase in body weight. CONCLUSIONS: Weight gain was associated with chemotherapy treatment either alone or in combination with radiotherapy. |
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Effect of adjuvant antineoplastic treatment on body weight change in women with breast cancerEfeito do tratamento antineoplásico adjuvante na mudança de peso corporal em mulheres com câncer de mama [Resumo em Português]BODY MASS INDEXWAIST CIRCUMFERENCEANTINEOPLASTIC THERAPY PROTOCOLSBREASTÍNDICE DE MASSA CORPORALCIRCUNFERÊNCIA DA CINTURAPROTOCOLOS DE QUIMIOTERAPIA ANTINEOPLÁSICACÂNCER DE MAMAENSAIO CLÍNICO.AIMS: To identify the effect of adjuvant antineoplastic treatment on body weight change of women with breast cancer. METHODS: A non-randomized clinical study included women with a recent surgical diagnosis of breast cancer, admitted to the Maternidade Carmela Dutra hospital in Florianópolis, Santa Catarina, southern Brazil, between October 2006 and July 2008. Food intake, weight, body mass index, hip circumference, waist circumference and other variables were measured before (baseline) and after the adjuvant antineoplastic treatment (pos-treatment). A mixed effects linear regression model was used to estimate the longitudinal changes occurring in weight. RESULTS: The sample comprised 53 patients. A significant increase (P less than 0.05) was observed in body weight (2.81 kg), body mass index (1.08 kg/m2), hip circumference (3.62 cm) and waist circumference (1.93 cm). In relation to diet, there was a significant increase (P less than 0.05) in the intake of energy (272.7 kcal), total fat (11.2 g) and polyunsaturated fatty acids (5.4 g). The final regression model for the change in body weight demonstrated that the women who were exposed to chemotherapy treatment, and to chemotherapy associated with radiotherapy, had the largest mean increase in body weight (2.47 kg and 5.21 kg, respectively). Socio-economic, demographic and nutritional factors were not associated with the increase in body weight. CONCLUSIONS: Weight gain was associated with chemotherapy treatment either alone or in combination with radiotherapy.OBJETIVOS: Identificar o efeito do tratamento antineoplásico adjuvante sobre a mudança de peso corporal em mulheres com câncer de mama. MÉTODOS: Um estudo clínico não randomizado incluiu mulheres com diagnóstico cirúrgico recente de câncer de mama, admitidas no hospital Maternidade Carmela Dutra em Florianópolis, Santa Catarina, entre outubro de 2006 e julho de 2008. Os dados de consumo alimentar, peso corporal, índice de massa corporal, circunferência do quadril, circunferência da cintura e outras variáveis, foram avaliados antes (basal) e depois do tratamento antineoplásico adjuvante (pós-tratamento). Um modelo de regressão linear de efeitos mistos foi utilizado para estimar as mudanças longitudinais que ocorreram no peso corporal. RESULTADOS: A amostra foi composta por 53 pacientes. Foi observado um aumento significativo (P menor que 0,05) no peso corporal (2,81 Kg), índice de massa corporal (1,08 Kg/m2), circunferência do quadril (3,62 cm) e circunferência da cintura (1,93 cm). Em relação aos aspectos dietéticos, houve um significativo aumento (P menor que 0,05) na ingestão de energia (272,7 kcal), gorduras totais (11,2 g) e ácidos graxos poliinsaturados (5,4 g). O modelo final para a mudança no peso corporal demonstrou que as mulheres as quais foram expostas ao tratamento quimioterápico, e quimioterápico associado ao radioterápico, tiveram um maior aumento médio no peso corporal (2,47 Kg e 5,21 kg, respectivamente). Os fatores socioeconômicos, demográficos e nutricionais não foram associados com o aumento no peso corporal. CONCLUSÕES: O aumento de peso esteve associado com o tratamento quimioterápico sozinho ou em combinação com o tratamento radioterápico.Editora da PUCRS - ediPUCRS2012-07-27info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://revistaseletronicas.pucrs.br/scientiamedica/article/view/1073810.15448/1980-6108.2012.3.10738Scientia Medica; Vol. 22 No. 3 (2012); 124-130Scientia Medica; v. 22 n. 3 (2012); 124-1301980-61081806-5562reponame:Scientia Medica (Porto Alegre. Online)instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)instacron:PUC_RSporenghttps://revistaseletronicas.pucrs.br/scientiamedica/article/view/10738/8176https://revistaseletronicas.pucrs.br/scientiamedica/article/view/10738/8177Ambrosi, ClaudiaDi Pietro, Patricia FariaVieira, Francilene Graciele KunradiRockenbach, GabrieleBoaventura, Brunna Cristina BremerGalvan, DaisyCrippa, Carlos GilbertoFausto, Maria Arleneinfo:eu-repo/semantics/openAccess2022-10-14T18:22:31Zoai:ojs.revistaseletronicas.pucrs.br:article/10738Revistahttps://revistaseletronicas.pucrs.br/scientiamedica/PUBhttps://revistaseletronicas.pucrs.br/scientiamedica/oaiscientiamedica@pucrs.br || editora.periodicos@pucrs.br1980-61081806-5562opendoar:2022-10-14T18:22:31Scientia Medica (Porto Alegre. Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)false |
dc.title.none.fl_str_mv |
Effect of adjuvant antineoplastic treatment on body weight change in women with breast cancer Efeito do tratamento antineoplásico adjuvante na mudança de peso corporal em mulheres com câncer de mama [Resumo em Português] |
title |
Effect of adjuvant antineoplastic treatment on body weight change in women with breast cancer |
spellingShingle |
Effect of adjuvant antineoplastic treatment on body weight change in women with breast cancer Ambrosi, Claudia BODY MASS INDEX WAIST CIRCUMFERENCE ANTINEOPLASTIC THERAPY PROTOCOLS BREAST ÍNDICE DE MASSA CORPORAL CIRCUNFERÊNCIA DA CINTURA PROTOCOLOS DE QUIMIOTERAPIA ANTINEOPLÁSICA CÂNCER DE MAMA ENSAIO CLÍNICO. |
title_short |
Effect of adjuvant antineoplastic treatment on body weight change in women with breast cancer |
title_full |
Effect of adjuvant antineoplastic treatment on body weight change in women with breast cancer |
title_fullStr |
Effect of adjuvant antineoplastic treatment on body weight change in women with breast cancer |
title_full_unstemmed |
Effect of adjuvant antineoplastic treatment on body weight change in women with breast cancer |
title_sort |
Effect of adjuvant antineoplastic treatment on body weight change in women with breast cancer |
author |
Ambrosi, Claudia |
author_facet |
Ambrosi, Claudia Di Pietro, Patricia Faria Vieira, Francilene Graciele Kunradi Rockenbach, Gabriele Boaventura, Brunna Cristina Bremer Galvan, Daisy Crippa, Carlos Gilberto Fausto, Maria Arlene |
author_role |
author |
author2 |
Di Pietro, Patricia Faria Vieira, Francilene Graciele Kunradi Rockenbach, Gabriele Boaventura, Brunna Cristina Bremer Galvan, Daisy Crippa, Carlos Gilberto Fausto, Maria Arlene |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Ambrosi, Claudia Di Pietro, Patricia Faria Vieira, Francilene Graciele Kunradi Rockenbach, Gabriele Boaventura, Brunna Cristina Bremer Galvan, Daisy Crippa, Carlos Gilberto Fausto, Maria Arlene |
dc.subject.por.fl_str_mv |
BODY MASS INDEX WAIST CIRCUMFERENCE ANTINEOPLASTIC THERAPY PROTOCOLS BREAST ÍNDICE DE MASSA CORPORAL CIRCUNFERÊNCIA DA CINTURA PROTOCOLOS DE QUIMIOTERAPIA ANTINEOPLÁSICA CÂNCER DE MAMA ENSAIO CLÍNICO. |
topic |
BODY MASS INDEX WAIST CIRCUMFERENCE ANTINEOPLASTIC THERAPY PROTOCOLS BREAST ÍNDICE DE MASSA CORPORAL CIRCUNFERÊNCIA DA CINTURA PROTOCOLOS DE QUIMIOTERAPIA ANTINEOPLÁSICA CÂNCER DE MAMA ENSAIO CLÍNICO. |
description |
AIMS: To identify the effect of adjuvant antineoplastic treatment on body weight change of women with breast cancer. METHODS: A non-randomized clinical study included women with a recent surgical diagnosis of breast cancer, admitted to the Maternidade Carmela Dutra hospital in Florianópolis, Santa Catarina, southern Brazil, between October 2006 and July 2008. Food intake, weight, body mass index, hip circumference, waist circumference and other variables were measured before (baseline) and after the adjuvant antineoplastic treatment (pos-treatment). A mixed effects linear regression model was used to estimate the longitudinal changes occurring in weight. RESULTS: The sample comprised 53 patients. A significant increase (P less than 0.05) was observed in body weight (2.81 kg), body mass index (1.08 kg/m2), hip circumference (3.62 cm) and waist circumference (1.93 cm). In relation to diet, there was a significant increase (P less than 0.05) in the intake of energy (272.7 kcal), total fat (11.2 g) and polyunsaturated fatty acids (5.4 g). The final regression model for the change in body weight demonstrated that the women who were exposed to chemotherapy treatment, and to chemotherapy associated with radiotherapy, had the largest mean increase in body weight (2.47 kg and 5.21 kg, respectively). Socio-economic, demographic and nutritional factors were not associated with the increase in body weight. CONCLUSIONS: Weight gain was associated with chemotherapy treatment either alone or in combination with radiotherapy. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-07-27 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://revistaseletronicas.pucrs.br/scientiamedica/article/view/10738 10.15448/1980-6108.2012.3.10738 |
url |
https://revistaseletronicas.pucrs.br/scientiamedica/article/view/10738 |
identifier_str_mv |
10.15448/1980-6108.2012.3.10738 |
dc.language.iso.fl_str_mv |
por eng |
language |
por eng |
dc.relation.none.fl_str_mv |
https://revistaseletronicas.pucrs.br/scientiamedica/article/view/10738/8176 https://revistaseletronicas.pucrs.br/scientiamedica/article/view/10738/8177 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Editora da PUCRS - ediPUCRS |
publisher.none.fl_str_mv |
Editora da PUCRS - ediPUCRS |
dc.source.none.fl_str_mv |
Scientia Medica; Vol. 22 No. 3 (2012); 124-130 Scientia Medica; v. 22 n. 3 (2012); 124-130 1980-6108 1806-5562 reponame:Scientia Medica (Porto Alegre. Online) instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) instacron:PUC_RS |
instname_str |
Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) |
instacron_str |
PUC_RS |
institution |
PUC_RS |
reponame_str |
Scientia Medica (Porto Alegre. Online) |
collection |
Scientia Medica (Porto Alegre. Online) |
repository.name.fl_str_mv |
Scientia Medica (Porto Alegre. Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) |
repository.mail.fl_str_mv |
scientiamedica@pucrs.br || editora.periodicos@pucrs.br |
_version_ |
1809101749621882880 |