Effect of adjuvant antineoplastic treatment on body weight change in women with breast cancer

Detalhes bibliográficos
Autor(a) principal: Ambrosi, Claudia
Data de Publicação: 2012
Outros Autores: Di Pietro, Patricia Faria, Vieira, Francilene Graciele Kunradi, Rockenbach, Gabriele, Boaventura, Brunna Cristina Bremer, Galvan, Daisy, Crippa, Carlos Gilberto, Fausto, Maria Arlene
Tipo de documento: Artigo
Idioma: por
eng
Título da fonte: Scientia Medica (Porto Alegre. Online)
Texto Completo: https://revistaseletronicas.pucrs.br/scientiamedica/article/view/10738
Resumo: AIMS: To identify the effect of adjuvant antineoplastic treatment on body weight change of women with breast cancer. METHODS: A non-randomized clinical study included women with a recent surgical diagnosis of breast cancer, admitted to the Maternidade Carmela Dutra hospital in Florianópolis, Santa Catarina, southern Brazil, between October 2006 and July 2008. Food intake, weight, body mass index, hip circumference, waist circumference and other variables were measured before (baseline) and after the adjuvant antineoplastic treatment (pos-treatment). A mixed effects linear regression model was used to estimate the longitudinal changes occurring in weight. RESULTS: The sample comprised 53 patients. A significant increase (P less than 0.05) was observed in body weight (2.81 kg), body mass index (1.08 kg/m2), hip circumference (3.62 cm) and waist circumference (1.93 cm). In relation to diet, there was a significant increase (P less than 0.05) in the intake of energy (272.7 kcal), total fat (11.2 g) and polyunsaturated fatty acids (5.4 g). The final regression model for the change in body weight demonstrated that the women who were exposed to chemotherapy treatment, and to chemotherapy associated with radiotherapy, had the largest mean increase in body weight (2.47 kg and 5.21 kg, respectively). Socio-economic, demographic and nutritional factors were not associated with the increase in body weight. CONCLUSIONS: Weight gain was associated with chemotherapy treatment either alone or in combination with radiotherapy.
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spelling Effect of adjuvant antineoplastic treatment on body weight change in women with breast cancerEfeito do tratamento antineoplásico adjuvante na mudança de peso corporal em mulheres com câncer de mama [Resumo em Português]BODY MASS INDEXWAIST CIRCUMFERENCEANTINEOPLASTIC THERAPY PROTOCOLSBREASTÍNDICE DE MASSA CORPORALCIRCUNFERÊNCIA DA CINTURAPROTOCOLOS DE QUIMIOTERAPIA ANTINEOPLÁSICACÂNCER DE MAMAENSAIO CLÍNICO.AIMS: To identify the effect of adjuvant antineoplastic treatment on body weight change of women with breast cancer. METHODS: A non-randomized clinical study included women with a recent surgical diagnosis of breast cancer, admitted to the Maternidade Carmela Dutra hospital in Florianópolis, Santa Catarina, southern Brazil, between October 2006 and July 2008. Food intake, weight, body mass index, hip circumference, waist circumference and other variables were measured before (baseline) and after the adjuvant antineoplastic treatment (pos-treatment). A mixed effects linear regression model was used to estimate the longitudinal changes occurring in weight. RESULTS: The sample comprised 53 patients. A significant increase (P less than 0.05) was observed in body weight (2.81 kg), body mass index (1.08 kg/m2), hip circumference (3.62 cm) and waist circumference (1.93 cm). In relation to diet, there was a significant increase (P less than 0.05) in the intake of energy (272.7 kcal), total fat (11.2 g) and polyunsaturated fatty acids (5.4 g). The final regression model for the change in body weight demonstrated that the women who were exposed to chemotherapy treatment, and to chemotherapy associated with radiotherapy, had the largest mean increase in body weight (2.47 kg and 5.21 kg, respectively). Socio-economic, demographic and nutritional factors were not associated with the increase in body weight. CONCLUSIONS: Weight gain was associated with chemotherapy treatment either alone or in combination with radiotherapy.OBJETIVOS: Identificar o efeito do tratamento antineoplásico adjuvante sobre a mudança de peso corporal em mulheres com câncer de mama. MÉTODOS: Um estudo clínico não randomizado incluiu mulheres com diagnóstico cirúrgico recente de câncer de mama, admitidas no hospital Maternidade Carmela Dutra em Florianópolis, Santa Catarina, entre outubro de 2006 e julho de 2008. Os dados de consumo alimentar, peso corporal, índice de massa corporal, circunferência do quadril, circunferência da cintura e outras variáveis, foram avaliados antes (basal) e depois do tratamento antineoplásico adjuvante (pós-tratamento). Um modelo de regressão linear de efeitos mistos foi utilizado para estimar as mudanças longitudinais que ocorreram no peso corporal. RESULTADOS: A amostra foi composta por 53 pacientes. Foi observado um aumento significativo (P menor que 0,05) no peso corporal (2,81 Kg), índice de massa corporal (1,08 Kg/m2), circunferência do quadril (3,62 cm) e circunferência da cintura (1,93 cm). Em relação aos aspectos dietéticos, houve um significativo aumento (P menor que 0,05) na ingestão de energia (272,7 kcal), gorduras totais (11,2 g) e ácidos graxos poliinsaturados (5,4 g). O modelo final para a mudança no peso corporal demonstrou que as mulheres as quais foram expostas ao tratamento quimioterápico, e quimioterápico associado ao radioterápico, tiveram um maior aumento médio no peso corporal (2,47 Kg e 5,21 kg, respectivamente). Os fatores socioeconômicos, demográficos e nutricionais não foram associados com o aumento no peso corporal. CONCLUSÕES: O aumento de peso esteve associado com o tratamento quimioterápico sozinho ou em combinação com o tratamento radioterápico.Editora da PUCRS - ediPUCRS2012-07-27info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://revistaseletronicas.pucrs.br/scientiamedica/article/view/1073810.15448/1980-6108.2012.3.10738Scientia Medica; Vol. 22 No. 3 (2012); 124-130Scientia Medica; v. 22 n. 3 (2012); 124-1301980-61081806-5562reponame:Scientia Medica (Porto Alegre. Online)instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)instacron:PUC_RSporenghttps://revistaseletronicas.pucrs.br/scientiamedica/article/view/10738/8176https://revistaseletronicas.pucrs.br/scientiamedica/article/view/10738/8177Ambrosi, ClaudiaDi Pietro, Patricia FariaVieira, Francilene Graciele KunradiRockenbach, GabrieleBoaventura, Brunna Cristina BremerGalvan, DaisyCrippa, Carlos GilbertoFausto, Maria Arleneinfo:eu-repo/semantics/openAccess2022-10-14T18:22:31Zoai:ojs.revistaseletronicas.pucrs.br:article/10738Revistahttps://revistaseletronicas.pucrs.br/scientiamedica/PUBhttps://revistaseletronicas.pucrs.br/scientiamedica/oaiscientiamedica@pucrs.br || editora.periodicos@pucrs.br1980-61081806-5562opendoar:2022-10-14T18:22:31Scientia Medica (Porto Alegre. Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)false
dc.title.none.fl_str_mv Effect of adjuvant antineoplastic treatment on body weight change in women with breast cancer
Efeito do tratamento antineoplásico adjuvante na mudança de peso corporal em mulheres com câncer de mama [Resumo em Português]
title Effect of adjuvant antineoplastic treatment on body weight change in women with breast cancer
spellingShingle Effect of adjuvant antineoplastic treatment on body weight change in women with breast cancer
Ambrosi, Claudia
BODY MASS INDEX
WAIST CIRCUMFERENCE
ANTINEOPLASTIC THERAPY PROTOCOLS
BREAST
ÍNDICE DE MASSA CORPORAL
CIRCUNFERÊNCIA DA CINTURA
PROTOCOLOS DE QUIMIOTERAPIA ANTINEOPLÁSICA
CÂNCER DE MAMA
ENSAIO CLÍNICO.
title_short Effect of adjuvant antineoplastic treatment on body weight change in women with breast cancer
title_full Effect of adjuvant antineoplastic treatment on body weight change in women with breast cancer
title_fullStr Effect of adjuvant antineoplastic treatment on body weight change in women with breast cancer
title_full_unstemmed Effect of adjuvant antineoplastic treatment on body weight change in women with breast cancer
title_sort Effect of adjuvant antineoplastic treatment on body weight change in women with breast cancer
author Ambrosi, Claudia
author_facet Ambrosi, Claudia
Di Pietro, Patricia Faria
Vieira, Francilene Graciele Kunradi
Rockenbach, Gabriele
Boaventura, Brunna Cristina Bremer
Galvan, Daisy
Crippa, Carlos Gilberto
Fausto, Maria Arlene
author_role author
author2 Di Pietro, Patricia Faria
Vieira, Francilene Graciele Kunradi
Rockenbach, Gabriele
Boaventura, Brunna Cristina Bremer
Galvan, Daisy
Crippa, Carlos Gilberto
Fausto, Maria Arlene
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Ambrosi, Claudia
Di Pietro, Patricia Faria
Vieira, Francilene Graciele Kunradi
Rockenbach, Gabriele
Boaventura, Brunna Cristina Bremer
Galvan, Daisy
Crippa, Carlos Gilberto
Fausto, Maria Arlene
dc.subject.por.fl_str_mv BODY MASS INDEX
WAIST CIRCUMFERENCE
ANTINEOPLASTIC THERAPY PROTOCOLS
BREAST
ÍNDICE DE MASSA CORPORAL
CIRCUNFERÊNCIA DA CINTURA
PROTOCOLOS DE QUIMIOTERAPIA ANTINEOPLÁSICA
CÂNCER DE MAMA
ENSAIO CLÍNICO.
topic BODY MASS INDEX
WAIST CIRCUMFERENCE
ANTINEOPLASTIC THERAPY PROTOCOLS
BREAST
ÍNDICE DE MASSA CORPORAL
CIRCUNFERÊNCIA DA CINTURA
PROTOCOLOS DE QUIMIOTERAPIA ANTINEOPLÁSICA
CÂNCER DE MAMA
ENSAIO CLÍNICO.
description AIMS: To identify the effect of adjuvant antineoplastic treatment on body weight change of women with breast cancer. METHODS: A non-randomized clinical study included women with a recent surgical diagnosis of breast cancer, admitted to the Maternidade Carmela Dutra hospital in Florianópolis, Santa Catarina, southern Brazil, between October 2006 and July 2008. Food intake, weight, body mass index, hip circumference, waist circumference and other variables were measured before (baseline) and after the adjuvant antineoplastic treatment (pos-treatment). A mixed effects linear regression model was used to estimate the longitudinal changes occurring in weight. RESULTS: The sample comprised 53 patients. A significant increase (P less than 0.05) was observed in body weight (2.81 kg), body mass index (1.08 kg/m2), hip circumference (3.62 cm) and waist circumference (1.93 cm). In relation to diet, there was a significant increase (P less than 0.05) in the intake of energy (272.7 kcal), total fat (11.2 g) and polyunsaturated fatty acids (5.4 g). The final regression model for the change in body weight demonstrated that the women who were exposed to chemotherapy treatment, and to chemotherapy associated with radiotherapy, had the largest mean increase in body weight (2.47 kg and 5.21 kg, respectively). Socio-economic, demographic and nutritional factors were not associated with the increase in body weight. CONCLUSIONS: Weight gain was associated with chemotherapy treatment either alone or in combination with radiotherapy.
publishDate 2012
dc.date.none.fl_str_mv 2012-07-27
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://revistaseletronicas.pucrs.br/scientiamedica/article/view/10738
10.15448/1980-6108.2012.3.10738
url https://revistaseletronicas.pucrs.br/scientiamedica/article/view/10738
identifier_str_mv 10.15448/1980-6108.2012.3.10738
dc.language.iso.fl_str_mv por
eng
language por
eng
dc.relation.none.fl_str_mv https://revistaseletronicas.pucrs.br/scientiamedica/article/view/10738/8176
https://revistaseletronicas.pucrs.br/scientiamedica/article/view/10738/8177
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Editora da PUCRS - ediPUCRS
publisher.none.fl_str_mv Editora da PUCRS - ediPUCRS
dc.source.none.fl_str_mv Scientia Medica; Vol. 22 No. 3 (2012); 124-130
Scientia Medica; v. 22 n. 3 (2012); 124-130
1980-6108
1806-5562
reponame:Scientia Medica (Porto Alegre. Online)
instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron:PUC_RS
instname_str Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron_str PUC_RS
institution PUC_RS
reponame_str Scientia Medica (Porto Alegre. Online)
collection Scientia Medica (Porto Alegre. Online)
repository.name.fl_str_mv Scientia Medica (Porto Alegre. Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
repository.mail.fl_str_mv scientiamedica@pucrs.br || editora.periodicos@pucrs.br
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