Factors related to decreased vitamin D levels in men with spinal cord injury living in a subtropical region
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Scientia Medica (Porto Alegre. Online) |
Texto Completo: | https://revistaseletronicas.pucrs.br/scientiamedica/article/view/28381 |
Resumo: | AIMS: To evaluate the levels of vitamin D, parathyroid hormone and calcium in individuals with spinal cord injury and to identify related factors.METHODS: A cross-sectional study included men with spinal cord injury, living in the South Region of Brazil. A questionnaire was applied to evaluate socioeconomic data, life habits and health. The time elapsed since the spinal cord injury was considered. Vitamin D was evaluated in plasma via liquid chromatography; calcium and PTH were measured in serum by a colorimetric method and electrochemiluminescence respectively. For data analysis, linear regression and chi-square test were utilized. Values of p<0.05 were considered significant. RESULTS: The study included 39 paraplegic or tetraplegic men with spinal cord injury. The mean age was 35.52±9.78 years, and the mean time since injury was 6.09±5.55 years. The mean biochemical levels were: 19.0 ±6.98 ng/mL for vitamin D; 9.54±0.52 mg/dL for total calcium; and 34.81±10.84 pg/mL for parathyroid hormone. Individuals with sun exposure for more than two hours daily had higher vitamin D levels than those exposed up to one hour per day (p=0.001). Linear regression identified an inverse relationship between lesion time and vitamin D levels (regression coefficient: -0.424; p=0.029), while the other parameters did not show significant differences regarding the time elapsed since the lesion. Subjects with income above four minimum wages had higher vitamin D values (mean 25.67±5.45 ng/mL) when compared to those with income up to four minimum wages (mean 18.43±6.79 ng/mL) (p=0.021). CONCLUSIONS: Levels of vitamin D were inversely correlated to the time elapsed since the spinal cord injury, probably due to insufficient sun exposure resulting from prolonged limitation of mobility. In addition, lower levels of vitamin D were associated to lower income. These factors may aggravate bone loss associated with decreased mobility resulting from spinal cord injury. |
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Factors related to decreased vitamin D levels in men with spinal cord injury living in a subtropical regionFactors related to decreased vitamin D levels in men with spinal cord injury living in a subtropical regionVitamin Dparathyroid hormonespinal cord injuryparaplegiamonthly incomesocioeconomic status.vitamina Dhormônio paratireóideotraumatismos da medula espinhalparaplegiarenda mensalsituação socioeconômica.AIMS: To evaluate the levels of vitamin D, parathyroid hormone and calcium in individuals with spinal cord injury and to identify related factors.METHODS: A cross-sectional study included men with spinal cord injury, living in the South Region of Brazil. A questionnaire was applied to evaluate socioeconomic data, life habits and health. The time elapsed since the spinal cord injury was considered. Vitamin D was evaluated in plasma via liquid chromatography; calcium and PTH were measured in serum by a colorimetric method and electrochemiluminescence respectively. For data analysis, linear regression and chi-square test were utilized. Values of p<0.05 were considered significant. RESULTS: The study included 39 paraplegic or tetraplegic men with spinal cord injury. The mean age was 35.52±9.78 years, and the mean time since injury was 6.09±5.55 years. The mean biochemical levels were: 19.0 ±6.98 ng/mL for vitamin D; 9.54±0.52 mg/dL for total calcium; and 34.81±10.84 pg/mL for parathyroid hormone. Individuals with sun exposure for more than two hours daily had higher vitamin D levels than those exposed up to one hour per day (p=0.001). Linear regression identified an inverse relationship between lesion time and vitamin D levels (regression coefficient: -0.424; p=0.029), while the other parameters did not show significant differences regarding the time elapsed since the lesion. Subjects with income above four minimum wages had higher vitamin D values (mean 25.67±5.45 ng/mL) when compared to those with income up to four minimum wages (mean 18.43±6.79 ng/mL) (p=0.021). CONCLUSIONS: Levels of vitamin D were inversely correlated to the time elapsed since the spinal cord injury, probably due to insufficient sun exposure resulting from prolonged limitation of mobility. In addition, lower levels of vitamin D were associated to lower income. These factors may aggravate bone loss associated with decreased mobility resulting from spinal cord injury.***Fatores relacionados a níveis reduzidos de vitamina D em homens com lesão da medula espinhal vivendo em uma região subtropical***OBJETIVOS: Avaliar os níveis de vitamina D, hormônio paratireoide e cálcio em indivíduos com lesão medular e identificar fatores relacionados.MÉTODOS: Estudo transversal incluiu homens com lesão da medula espinhal, vivendo na Região Sul do Brasil. Foi aplicado um questionário para avaliar dados socioeconômicos, hábitos de vida e saúde. Foi investigado o tempo transcorrido após a lesão medular. A vitamina D foi avaliada no plasma por meio de cromatografia líquida; o cálcio e o hormônio paratireoideo foram dosados no soro por um método colorimétrico e eletroquimioluminescência respectivamente. Para a análise de dados, foram utilizadas regressão linear e teste do qui-quadrado. Valores de p<0,05 foram considerados significativos.RESULTADOS: O estudo incluiu 39 homens paraplégicos ou tetraplégicos com lesão da medula espinhal. A média de idade foi de 35,52±9,78 anos e o tempo médio de lesão foi de 6,09±5,55 anos. As médias dos níveis bioquímicos foram: 19,0±6,98 ng/mL para vitamina D, 9,54±0,52 mg/dL para cálcio total e 34,81±10,84 pg/mL para hormônio paratireoideo. Indivíduos com exposição ao sol por mais de duas horas por dia apresentaram maiores níveis de vitamina D do que os expostos até uma hora por dia (p=0,001). A regressão linear identificou uma relação inversa entre o tempo de lesão e os níveis de vitamina D (coeficiente de regressão: -0,424; p=0,029), enquanto os outros parâmetros não apresentaram diferença significativa em relação ao tempo decorrido desde a lesão. Os indivíduos com renda acima de quatro salários mínimos apresentaram maiores valores de vitamina D (média de 25,67±5,45 ng/mL) quando comparados com aqueles com renda até quatro salários mínimos (média 18,43±6,79 ng/mL) (p=0,021).CONCLUSÕES: Os níveis de vitamina D foram inversamente correlacionados com o tempo decorrido desde a lesão da medula espinhal, provavelmente devido à exposição insuficiente ao sol resultante da limitação prolongada da mobilidade. Níveis mais baixos de vitamina D foram associados a menor renda. Estes fatores podem agravar a perda óssea associada à diminuição da mobilidade resultante da lesão da medula espinhal.Editora da PUCRS - ediPUCRS2018-02-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revistaseletronicas.pucrs.br/scientiamedica/article/view/2838110.15448/1980-6108.2018.2.28381Scientia Medica; Vol. 28 No. 2 (2018); ID28381Scientia Medica; v. 28 n. 2 (2018); ID283811980-61081806-556210.15448/1980-6108.2018.2reponame:Scientia Medica (Porto Alegre. Online)instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)instacron:PUC_RSenghttps://revistaseletronicas.pucrs.br/scientiamedica/article/view/28381/16492Copyright (c) 2018 Scientia Medicainfo:eu-repo/semantics/openAccessBassuino, Mauricio SprengerKaminski, Elisa LettninGarcia, Laís OliveiraLinden, RafaelAntunes, Marina VenzonSchneider, Rodolfo HerbertoMachado, Denise Cantarelli2018-06-16T17:36:13Zoai:ojs.revistaseletronicas.pucrs.br:article/28381Revistahttps://revistaseletronicas.pucrs.br/scientiamedica/PUBhttps://revistaseletronicas.pucrs.br/scientiamedica/oaiscientiamedica@pucrs.br || editora.periodicos@pucrs.br1980-61081806-5562opendoar:2018-06-16T17:36:13Scientia Medica (Porto Alegre. Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)false |
dc.title.none.fl_str_mv |
Factors related to decreased vitamin D levels in men with spinal cord injury living in a subtropical region Factors related to decreased vitamin D levels in men with spinal cord injury living in a subtropical region |
title |
Factors related to decreased vitamin D levels in men with spinal cord injury living in a subtropical region |
spellingShingle |
Factors related to decreased vitamin D levels in men with spinal cord injury living in a subtropical region Bassuino, Mauricio Sprenger Vitamin D parathyroid hormone spinal cord injury paraplegia monthly income socioeconomic status. vitamina D hormônio paratireóideo traumatismos da medula espinhal paraplegia renda mensal situação socioeconômica. |
title_short |
Factors related to decreased vitamin D levels in men with spinal cord injury living in a subtropical region |
title_full |
Factors related to decreased vitamin D levels in men with spinal cord injury living in a subtropical region |
title_fullStr |
Factors related to decreased vitamin D levels in men with spinal cord injury living in a subtropical region |
title_full_unstemmed |
Factors related to decreased vitamin D levels in men with spinal cord injury living in a subtropical region |
title_sort |
Factors related to decreased vitamin D levels in men with spinal cord injury living in a subtropical region |
author |
Bassuino, Mauricio Sprenger |
author_facet |
Bassuino, Mauricio Sprenger Kaminski, Elisa Lettnin Garcia, Laís Oliveira Linden, Rafael Antunes, Marina Venzon Schneider, Rodolfo Herberto Machado, Denise Cantarelli |
author_role |
author |
author2 |
Kaminski, Elisa Lettnin Garcia, Laís Oliveira Linden, Rafael Antunes, Marina Venzon Schneider, Rodolfo Herberto Machado, Denise Cantarelli |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Bassuino, Mauricio Sprenger Kaminski, Elisa Lettnin Garcia, Laís Oliveira Linden, Rafael Antunes, Marina Venzon Schneider, Rodolfo Herberto Machado, Denise Cantarelli |
dc.subject.por.fl_str_mv |
Vitamin D parathyroid hormone spinal cord injury paraplegia monthly income socioeconomic status. vitamina D hormônio paratireóideo traumatismos da medula espinhal paraplegia renda mensal situação socioeconômica. |
topic |
Vitamin D parathyroid hormone spinal cord injury paraplegia monthly income socioeconomic status. vitamina D hormônio paratireóideo traumatismos da medula espinhal paraplegia renda mensal situação socioeconômica. |
description |
AIMS: To evaluate the levels of vitamin D, parathyroid hormone and calcium in individuals with spinal cord injury and to identify related factors.METHODS: A cross-sectional study included men with spinal cord injury, living in the South Region of Brazil. A questionnaire was applied to evaluate socioeconomic data, life habits and health. The time elapsed since the spinal cord injury was considered. Vitamin D was evaluated in plasma via liquid chromatography; calcium and PTH were measured in serum by a colorimetric method and electrochemiluminescence respectively. For data analysis, linear regression and chi-square test were utilized. Values of p<0.05 were considered significant. RESULTS: The study included 39 paraplegic or tetraplegic men with spinal cord injury. The mean age was 35.52±9.78 years, and the mean time since injury was 6.09±5.55 years. The mean biochemical levels were: 19.0 ±6.98 ng/mL for vitamin D; 9.54±0.52 mg/dL for total calcium; and 34.81±10.84 pg/mL for parathyroid hormone. Individuals with sun exposure for more than two hours daily had higher vitamin D levels than those exposed up to one hour per day (p=0.001). Linear regression identified an inverse relationship between lesion time and vitamin D levels (regression coefficient: -0.424; p=0.029), while the other parameters did not show significant differences regarding the time elapsed since the lesion. Subjects with income above four minimum wages had higher vitamin D values (mean 25.67±5.45 ng/mL) when compared to those with income up to four minimum wages (mean 18.43±6.79 ng/mL) (p=0.021). CONCLUSIONS: Levels of vitamin D were inversely correlated to the time elapsed since the spinal cord injury, probably due to insufficient sun exposure resulting from prolonged limitation of mobility. In addition, lower levels of vitamin D were associated to lower income. These factors may aggravate bone loss associated with decreased mobility resulting from spinal cord injury. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-02-07 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://revistaseletronicas.pucrs.br/scientiamedica/article/view/28381 10.15448/1980-6108.2018.2.28381 |
url |
https://revistaseletronicas.pucrs.br/scientiamedica/article/view/28381 |
identifier_str_mv |
10.15448/1980-6108.2018.2.28381 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://revistaseletronicas.pucrs.br/scientiamedica/article/view/28381/16492 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2018 Scientia Medica info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2018 Scientia Medica |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Editora da PUCRS - ediPUCRS |
publisher.none.fl_str_mv |
Editora da PUCRS - ediPUCRS |
dc.source.none.fl_str_mv |
Scientia Medica; Vol. 28 No. 2 (2018); ID28381 Scientia Medica; v. 28 n. 2 (2018); ID28381 1980-6108 1806-5562 10.15448/1980-6108.2018.2 reponame:Scientia Medica (Porto Alegre. Online) instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) instacron:PUC_RS |
instname_str |
Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) |
instacron_str |
PUC_RS |
institution |
PUC_RS |
reponame_str |
Scientia Medica (Porto Alegre. Online) |
collection |
Scientia Medica (Porto Alegre. Online) |
repository.name.fl_str_mv |
Scientia Medica (Porto Alegre. Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) |
repository.mail.fl_str_mv |
scientiamedica@pucrs.br || editora.periodicos@pucrs.br |
_version_ |
1809101751449550848 |