Effects of oregano (Origanum vulgare) tea on the biochemical profile of Wistar rats [Abstract in English]

Detalhes bibliográficos
Autor(a) principal: Coqueiro, Daniel Pereira
Data de Publicação: 2012
Outros Autores: Bueno, Patricia Cincotto dos Santos, Guiguer, Elen Landragf, Barbalho, Sandra Maria, Souza, Maricelma da Silva Soares, Araújo, Adriano Cressoni, Torres, Cleber da Silveira, Scacco, Gustavo, Tiveron, Ana Maria, Costa, Juliana Machado, Vanzo, Layra Abib, Silva, Leandro de Oliveira, Gil, Murilo Salani, Abib, Murilo Delboni, Rossi, Paulo Brito Reis, Ozi, Rafael Fontes, Abib, Thays Delboni, Gonçalves, Ulisses Moraes
Tipo de documento: Artigo
Idioma: por
eng
Título da fonte: Scientia Medica (Porto Alegre. Online)
Texto Completo: https://revistaseletronicas.pucrs.br/scientiamedica/article/view/11494
Resumo: AIMS: To evaluate the effects of oregano tea (infusion) on biochemical profile and body weight of Wistar rats. METHODS: Twenty male Wistar rats were divided into two groups of 10 animals each: a treated group, which for 30 days received an infusion of oregano (oregano tea) as the only fluid intake, and a control group, which during the same period received pure water. All animals had free access to the same kind of chow and the liquid (water or oregano tea) was offered ad libitum. The rats were weighed weekly, and their body weights were recorded at 1st, 8th, 15th, 23rd, and 30th days. On day 30, the animals were anesthetized and euthanized with sodium pentobarbital. Blood samples were collected in order to determine total cholesterol, HDL-cholesterol, triglycerides, blood glucose, C-reactive protein, creatinine, aspartate aminotransferase and alanine aminotransferase. RESULTS: The animals that received the infusion of oregano had a lower blood glucose (135.20 ± 22.09) when compared to the control group (152.00 ± 16:51) (p less than 0.05). There were no significant changes in total cholesterol, triglyceride and HDL-cholesterol or in weight gain and the rate of weight gain. CONCLUSIONS: The study of the effects of oregano tea in rats suggests that this plant might have beneficial effects on blood glucose control. It is proposed that further clinical studies are carried out with different concentrations and time periods.
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spelling Effects of oregano (Origanum vulgare) tea on the biochemical profile of Wistar rats [Abstract in English]Efeitos do chá de orégano (Origanum vulgare) no perfil bioquímico de ratos WistarOriganum VulgareOregano PlantBlood GlucoseRatsModelsAnimal.Origanum VulgareOréganoGlicemiaRatosModelos Animais.AIMS: To evaluate the effects of oregano tea (infusion) on biochemical profile and body weight of Wistar rats. METHODS: Twenty male Wistar rats were divided into two groups of 10 animals each: a treated group, which for 30 days received an infusion of oregano (oregano tea) as the only fluid intake, and a control group, which during the same period received pure water. All animals had free access to the same kind of chow and the liquid (water or oregano tea) was offered ad libitum. The rats were weighed weekly, and their body weights were recorded at 1st, 8th, 15th, 23rd, and 30th days. On day 30, the animals were anesthetized and euthanized with sodium pentobarbital. Blood samples were collected in order to determine total cholesterol, HDL-cholesterol, triglycerides, blood glucose, C-reactive protein, creatinine, aspartate aminotransferase and alanine aminotransferase. RESULTS: The animals that received the infusion of oregano had a lower blood glucose (135.20 ± 22.09) when compared to the control group (152.00 ± 16:51) (p less than 0.05). There were no significant changes in total cholesterol, triglyceride and HDL-cholesterol or in weight gain and the rate of weight gain. CONCLUSIONS: The study of the effects of oregano tea in rats suggests that this plant might have beneficial effects on blood glucose control. It is proposed that further clinical studies are carried out with different concentrations and time periods.OBJETIVO: Avaliar os efeitos do chá (infusão) de orégano sobre o perfil bioquímico e peso corporal de ratos Wistar. MÉTODOS: Foram utilizados para o experimento 20 ratos Wistar machos divididos em dois grupos de 10 animais em cada: um grupo tratado, que durante 30 dias recebeu como única ingesta hídrica uma infusão de folhas de orégano (chá de orégano), e um grupo controle, que durante o mesmo período recebeu água pura. Todos os animais tiveram livre acesso ao mesmo tipo de ração e o líquido (água ou chá de orégano) foi ofertado ad libitum. Foram realizadas pesagens semanais, registrando os pesos corporais dos animais no 1º, 8º, 15º, 23º e 30º dias. No 30º dia do experimento os animais foram anestesiados e sacrificados com pentobarbital sódico. Foram coletadas amostras de sangue a fim de determinar colesterol total, HDL-colesterol, triglicerídeos, glicemia, proteína C reativa, creatinina, aspartato aminotransferase e alanina aminotransferase. RESULTADOS: Os animais que receberam o chá de orégano tiveram uma glicemia menor (135,20±22,09) quando comparados ao grupo controle (152,00±16,51) (p menor do que 0,05). Não foram encontradas diferenças significativas entre os dois grupos nos níveis de colesterol total, triglicerídeos e HDL-colesterol, nem no ganho de peso médio ou no percentual de ganho de peso. CONCLUSÕES: O estudo dos efeitos do chá de orégano em ratos sugere que essa planta pode ter efeitos benéficos na manutenção da glicemia. Propõe-se que mais estudos clínicos sejam realizados com diferentes concentrações e períodos de tempo.Editora da PUCRS - ediPUCRS2012-12-21info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://revistaseletronicas.pucrs.br/scientiamedica/article/view/11494Scientia Medica; Vol. 22 No. 4 (2012); 191-196Scientia Medica; v. 22 n. 4 (2012); 191-1961980-61081806-5562reponame:Scientia Medica (Porto Alegre. Online)instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)instacron:PUC_RSporenghttps://revistaseletronicas.pucrs.br/scientiamedica/article/view/11494/8617https://revistaseletronicas.pucrs.br/scientiamedica/article/view/11494/8618Coqueiro, Daniel PereiraBueno, Patricia Cincotto dos SantosGuiguer, Elen LandragfBarbalho, Sandra MariaSouza, Maricelma da Silva SoaresAraújo, Adriano CressoniTorres, Cleber da SilveiraScacco, GustavoTiveron, Ana MariaCosta, Juliana MachadoVanzo, Layra AbibSilva, Leandro de OliveiraGil, Murilo SalaniAbib, Murilo DelboniRossi, Paulo Brito ReisOzi, Rafael FontesAbib, Thays DelboniGonçalves, Ulisses Moraesinfo:eu-repo/semantics/openAccess2013-07-15T18:01:11Zoai:ojs.revistaseletronicas.pucrs.br:article/11494Revistahttps://revistaseletronicas.pucrs.br/scientiamedica/PUBhttps://revistaseletronicas.pucrs.br/scientiamedica/oaiscientiamedica@pucrs.br || editora.periodicos@pucrs.br1980-61081806-5562opendoar:2013-07-15T18:01:11Scientia Medica (Porto Alegre. Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)false
dc.title.none.fl_str_mv Effects of oregano (Origanum vulgare) tea on the biochemical profile of Wistar rats [Abstract in English]
Efeitos do chá de orégano (Origanum vulgare) no perfil bioquímico de ratos Wistar
title Effects of oregano (Origanum vulgare) tea on the biochemical profile of Wistar rats [Abstract in English]
spellingShingle Effects of oregano (Origanum vulgare) tea on the biochemical profile of Wistar rats [Abstract in English]
Coqueiro, Daniel Pereira
Origanum Vulgare
Oregano Plant
Blood Glucose
Rats
Models
Animal.
Origanum Vulgare
Orégano
Glicemia
Ratos
Modelos Animais.
title_short Effects of oregano (Origanum vulgare) tea on the biochemical profile of Wistar rats [Abstract in English]
title_full Effects of oregano (Origanum vulgare) tea on the biochemical profile of Wistar rats [Abstract in English]
title_fullStr Effects of oregano (Origanum vulgare) tea on the biochemical profile of Wistar rats [Abstract in English]
title_full_unstemmed Effects of oregano (Origanum vulgare) tea on the biochemical profile of Wistar rats [Abstract in English]
title_sort Effects of oregano (Origanum vulgare) tea on the biochemical profile of Wistar rats [Abstract in English]
author Coqueiro, Daniel Pereira
author_facet Coqueiro, Daniel Pereira
Bueno, Patricia Cincotto dos Santos
Guiguer, Elen Landragf
Barbalho, Sandra Maria
Souza, Maricelma da Silva Soares
Araújo, Adriano Cressoni
Torres, Cleber da Silveira
Scacco, Gustavo
Tiveron, Ana Maria
Costa, Juliana Machado
Vanzo, Layra Abib
Silva, Leandro de Oliveira
Gil, Murilo Salani
Abib, Murilo Delboni
Rossi, Paulo Brito Reis
Ozi, Rafael Fontes
Abib, Thays Delboni
Gonçalves, Ulisses Moraes
author_role author
author2 Bueno, Patricia Cincotto dos Santos
Guiguer, Elen Landragf
Barbalho, Sandra Maria
Souza, Maricelma da Silva Soares
Araújo, Adriano Cressoni
Torres, Cleber da Silveira
Scacco, Gustavo
Tiveron, Ana Maria
Costa, Juliana Machado
Vanzo, Layra Abib
Silva, Leandro de Oliveira
Gil, Murilo Salani
Abib, Murilo Delboni
Rossi, Paulo Brito Reis
Ozi, Rafael Fontes
Abib, Thays Delboni
Gonçalves, Ulisses Moraes
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Coqueiro, Daniel Pereira
Bueno, Patricia Cincotto dos Santos
Guiguer, Elen Landragf
Barbalho, Sandra Maria
Souza, Maricelma da Silva Soares
Araújo, Adriano Cressoni
Torres, Cleber da Silveira
Scacco, Gustavo
Tiveron, Ana Maria
Costa, Juliana Machado
Vanzo, Layra Abib
Silva, Leandro de Oliveira
Gil, Murilo Salani
Abib, Murilo Delboni
Rossi, Paulo Brito Reis
Ozi, Rafael Fontes
Abib, Thays Delboni
Gonçalves, Ulisses Moraes
dc.subject.por.fl_str_mv Origanum Vulgare
Oregano Plant
Blood Glucose
Rats
Models
Animal.
Origanum Vulgare
Orégano
Glicemia
Ratos
Modelos Animais.
topic Origanum Vulgare
Oregano Plant
Blood Glucose
Rats
Models
Animal.
Origanum Vulgare
Orégano
Glicemia
Ratos
Modelos Animais.
description AIMS: To evaluate the effects of oregano tea (infusion) on biochemical profile and body weight of Wistar rats. METHODS: Twenty male Wistar rats were divided into two groups of 10 animals each: a treated group, which for 30 days received an infusion of oregano (oregano tea) as the only fluid intake, and a control group, which during the same period received pure water. All animals had free access to the same kind of chow and the liquid (water or oregano tea) was offered ad libitum. The rats were weighed weekly, and their body weights were recorded at 1st, 8th, 15th, 23rd, and 30th days. On day 30, the animals were anesthetized and euthanized with sodium pentobarbital. Blood samples were collected in order to determine total cholesterol, HDL-cholesterol, triglycerides, blood glucose, C-reactive protein, creatinine, aspartate aminotransferase and alanine aminotransferase. RESULTS: The animals that received the infusion of oregano had a lower blood glucose (135.20 ± 22.09) when compared to the control group (152.00 ± 16:51) (p less than 0.05). There were no significant changes in total cholesterol, triglyceride and HDL-cholesterol or in weight gain and the rate of weight gain. CONCLUSIONS: The study of the effects of oregano tea in rats suggests that this plant might have beneficial effects on blood glucose control. It is proposed that further clinical studies are carried out with different concentrations and time periods.
publishDate 2012
dc.date.none.fl_str_mv 2012-12-21
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://revistaseletronicas.pucrs.br/scientiamedica/article/view/11494
url https://revistaseletronicas.pucrs.br/scientiamedica/article/view/11494
dc.language.iso.fl_str_mv por
eng
language por
eng
dc.relation.none.fl_str_mv https://revistaseletronicas.pucrs.br/scientiamedica/article/view/11494/8617
https://revistaseletronicas.pucrs.br/scientiamedica/article/view/11494/8618
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Editora da PUCRS - ediPUCRS
publisher.none.fl_str_mv Editora da PUCRS - ediPUCRS
dc.source.none.fl_str_mv Scientia Medica; Vol. 22 No. 4 (2012); 191-196
Scientia Medica; v. 22 n. 4 (2012); 191-196
1980-6108
1806-5562
reponame:Scientia Medica (Porto Alegre. Online)
instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron:PUC_RS
instname_str Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron_str PUC_RS
institution PUC_RS
reponame_str Scientia Medica (Porto Alegre. Online)
collection Scientia Medica (Porto Alegre. Online)
repository.name.fl_str_mv Scientia Medica (Porto Alegre. Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
repository.mail.fl_str_mv scientiamedica@pucrs.br || editora.periodicos@pucrs.br
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