Effects of oregano (Origanum vulgare) tea on the biochemical profile of Wistar rats [Abstract in English]
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por eng |
Título da fonte: | Scientia Medica (Porto Alegre. Online) |
Texto Completo: | https://revistaseletronicas.pucrs.br/scientiamedica/article/view/11494 |
Resumo: | AIMS: To evaluate the effects of oregano tea (infusion) on biochemical profile and body weight of Wistar rats. METHODS: Twenty male Wistar rats were divided into two groups of 10 animals each: a treated group, which for 30 days received an infusion of oregano (oregano tea) as the only fluid intake, and a control group, which during the same period received pure water. All animals had free access to the same kind of chow and the liquid (water or oregano tea) was offered ad libitum. The rats were weighed weekly, and their body weights were recorded at 1st, 8th, 15th, 23rd, and 30th days. On day 30, the animals were anesthetized and euthanized with sodium pentobarbital. Blood samples were collected in order to determine total cholesterol, HDL-cholesterol, triglycerides, blood glucose, C-reactive protein, creatinine, aspartate aminotransferase and alanine aminotransferase. RESULTS: The animals that received the infusion of oregano had a lower blood glucose (135.20 ± 22.09) when compared to the control group (152.00 ± 16:51) (p less than 0.05). There were no significant changes in total cholesterol, triglyceride and HDL-cholesterol or in weight gain and the rate of weight gain. CONCLUSIONS: The study of the effects of oregano tea in rats suggests that this plant might have beneficial effects on blood glucose control. It is proposed that further clinical studies are carried out with different concentrations and time periods. |
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Effects of oregano (Origanum vulgare) tea on the biochemical profile of Wistar rats [Abstract in English]Efeitos do chá de orégano (Origanum vulgare) no perfil bioquímico de ratos WistarOriganum VulgareOregano PlantBlood GlucoseRatsModelsAnimal.Origanum VulgareOréganoGlicemiaRatosModelos Animais.AIMS: To evaluate the effects of oregano tea (infusion) on biochemical profile and body weight of Wistar rats. METHODS: Twenty male Wistar rats were divided into two groups of 10 animals each: a treated group, which for 30 days received an infusion of oregano (oregano tea) as the only fluid intake, and a control group, which during the same period received pure water. All animals had free access to the same kind of chow and the liquid (water or oregano tea) was offered ad libitum. The rats were weighed weekly, and their body weights were recorded at 1st, 8th, 15th, 23rd, and 30th days. On day 30, the animals were anesthetized and euthanized with sodium pentobarbital. Blood samples were collected in order to determine total cholesterol, HDL-cholesterol, triglycerides, blood glucose, C-reactive protein, creatinine, aspartate aminotransferase and alanine aminotransferase. RESULTS: The animals that received the infusion of oregano had a lower blood glucose (135.20 ± 22.09) when compared to the control group (152.00 ± 16:51) (p less than 0.05). There were no significant changes in total cholesterol, triglyceride and HDL-cholesterol or in weight gain and the rate of weight gain. CONCLUSIONS: The study of the effects of oregano tea in rats suggests that this plant might have beneficial effects on blood glucose control. It is proposed that further clinical studies are carried out with different concentrations and time periods.OBJETIVO: Avaliar os efeitos do chá (infusão) de orégano sobre o perfil bioquímico e peso corporal de ratos Wistar. MÉTODOS: Foram utilizados para o experimento 20 ratos Wistar machos divididos em dois grupos de 10 animais em cada: um grupo tratado, que durante 30 dias recebeu como única ingesta hídrica uma infusão de folhas de orégano (chá de orégano), e um grupo controle, que durante o mesmo período recebeu água pura. Todos os animais tiveram livre acesso ao mesmo tipo de ração e o líquido (água ou chá de orégano) foi ofertado ad libitum. Foram realizadas pesagens semanais, registrando os pesos corporais dos animais no 1º, 8º, 15º, 23º e 30º dias. No 30º dia do experimento os animais foram anestesiados e sacrificados com pentobarbital sódico. Foram coletadas amostras de sangue a fim de determinar colesterol total, HDL-colesterol, triglicerídeos, glicemia, proteína C reativa, creatinina, aspartato aminotransferase e alanina aminotransferase. RESULTADOS: Os animais que receberam o chá de orégano tiveram uma glicemia menor (135,20±22,09) quando comparados ao grupo controle (152,00±16,51) (p menor do que 0,05). Não foram encontradas diferenças significativas entre os dois grupos nos níveis de colesterol total, triglicerídeos e HDL-colesterol, nem no ganho de peso médio ou no percentual de ganho de peso. CONCLUSÕES: O estudo dos efeitos do chá de orégano em ratos sugere que essa planta pode ter efeitos benéficos na manutenção da glicemia. Propõe-se que mais estudos clínicos sejam realizados com diferentes concentrações e períodos de tempo.Editora da PUCRS - ediPUCRS2012-12-21info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://revistaseletronicas.pucrs.br/scientiamedica/article/view/11494Scientia Medica; Vol. 22 No. 4 (2012); 191-196Scientia Medica; v. 22 n. 4 (2012); 191-1961980-61081806-5562reponame:Scientia Medica (Porto Alegre. Online)instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)instacron:PUC_RSporenghttps://revistaseletronicas.pucrs.br/scientiamedica/article/view/11494/8617https://revistaseletronicas.pucrs.br/scientiamedica/article/view/11494/8618Coqueiro, Daniel PereiraBueno, Patricia Cincotto dos SantosGuiguer, Elen LandragfBarbalho, Sandra MariaSouza, Maricelma da Silva SoaresAraújo, Adriano CressoniTorres, Cleber da SilveiraScacco, GustavoTiveron, Ana MariaCosta, Juliana MachadoVanzo, Layra AbibSilva, Leandro de OliveiraGil, Murilo SalaniAbib, Murilo DelboniRossi, Paulo Brito ReisOzi, Rafael FontesAbib, Thays DelboniGonçalves, Ulisses Moraesinfo:eu-repo/semantics/openAccess2013-07-15T18:01:11Zoai:ojs.revistaseletronicas.pucrs.br:article/11494Revistahttps://revistaseletronicas.pucrs.br/scientiamedica/PUBhttps://revistaseletronicas.pucrs.br/scientiamedica/oaiscientiamedica@pucrs.br || editora.periodicos@pucrs.br1980-61081806-5562opendoar:2013-07-15T18:01:11Scientia Medica (Porto Alegre. Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)false |
dc.title.none.fl_str_mv |
Effects of oregano (Origanum vulgare) tea on the biochemical profile of Wistar rats [Abstract in English] Efeitos do chá de orégano (Origanum vulgare) no perfil bioquímico de ratos Wistar |
title |
Effects of oregano (Origanum vulgare) tea on the biochemical profile of Wistar rats [Abstract in English] |
spellingShingle |
Effects of oregano (Origanum vulgare) tea on the biochemical profile of Wistar rats [Abstract in English] Coqueiro, Daniel Pereira Origanum Vulgare Oregano Plant Blood Glucose Rats Models Animal. Origanum Vulgare Orégano Glicemia Ratos Modelos Animais. |
title_short |
Effects of oregano (Origanum vulgare) tea on the biochemical profile of Wistar rats [Abstract in English] |
title_full |
Effects of oregano (Origanum vulgare) tea on the biochemical profile of Wistar rats [Abstract in English] |
title_fullStr |
Effects of oregano (Origanum vulgare) tea on the biochemical profile of Wistar rats [Abstract in English] |
title_full_unstemmed |
Effects of oregano (Origanum vulgare) tea on the biochemical profile of Wistar rats [Abstract in English] |
title_sort |
Effects of oregano (Origanum vulgare) tea on the biochemical profile of Wistar rats [Abstract in English] |
author |
Coqueiro, Daniel Pereira |
author_facet |
Coqueiro, Daniel Pereira Bueno, Patricia Cincotto dos Santos Guiguer, Elen Landragf Barbalho, Sandra Maria Souza, Maricelma da Silva Soares Araújo, Adriano Cressoni Torres, Cleber da Silveira Scacco, Gustavo Tiveron, Ana Maria Costa, Juliana Machado Vanzo, Layra Abib Silva, Leandro de Oliveira Gil, Murilo Salani Abib, Murilo Delboni Rossi, Paulo Brito Reis Ozi, Rafael Fontes Abib, Thays Delboni Gonçalves, Ulisses Moraes |
author_role |
author |
author2 |
Bueno, Patricia Cincotto dos Santos Guiguer, Elen Landragf Barbalho, Sandra Maria Souza, Maricelma da Silva Soares Araújo, Adriano Cressoni Torres, Cleber da Silveira Scacco, Gustavo Tiveron, Ana Maria Costa, Juliana Machado Vanzo, Layra Abib Silva, Leandro de Oliveira Gil, Murilo Salani Abib, Murilo Delboni Rossi, Paulo Brito Reis Ozi, Rafael Fontes Abib, Thays Delboni Gonçalves, Ulisses Moraes |
author2_role |
author author author author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Coqueiro, Daniel Pereira Bueno, Patricia Cincotto dos Santos Guiguer, Elen Landragf Barbalho, Sandra Maria Souza, Maricelma da Silva Soares Araújo, Adriano Cressoni Torres, Cleber da Silveira Scacco, Gustavo Tiveron, Ana Maria Costa, Juliana Machado Vanzo, Layra Abib Silva, Leandro de Oliveira Gil, Murilo Salani Abib, Murilo Delboni Rossi, Paulo Brito Reis Ozi, Rafael Fontes Abib, Thays Delboni Gonçalves, Ulisses Moraes |
dc.subject.por.fl_str_mv |
Origanum Vulgare Oregano Plant Blood Glucose Rats Models Animal. Origanum Vulgare Orégano Glicemia Ratos Modelos Animais. |
topic |
Origanum Vulgare Oregano Plant Blood Glucose Rats Models Animal. Origanum Vulgare Orégano Glicemia Ratos Modelos Animais. |
description |
AIMS: To evaluate the effects of oregano tea (infusion) on biochemical profile and body weight of Wistar rats. METHODS: Twenty male Wistar rats were divided into two groups of 10 animals each: a treated group, which for 30 days received an infusion of oregano (oregano tea) as the only fluid intake, and a control group, which during the same period received pure water. All animals had free access to the same kind of chow and the liquid (water or oregano tea) was offered ad libitum. The rats were weighed weekly, and their body weights were recorded at 1st, 8th, 15th, 23rd, and 30th days. On day 30, the animals were anesthetized and euthanized with sodium pentobarbital. Blood samples were collected in order to determine total cholesterol, HDL-cholesterol, triglycerides, blood glucose, C-reactive protein, creatinine, aspartate aminotransferase and alanine aminotransferase. RESULTS: The animals that received the infusion of oregano had a lower blood glucose (135.20 ± 22.09) when compared to the control group (152.00 ± 16:51) (p less than 0.05). There were no significant changes in total cholesterol, triglyceride and HDL-cholesterol or in weight gain and the rate of weight gain. CONCLUSIONS: The study of the effects of oregano tea in rats suggests that this plant might have beneficial effects on blood glucose control. It is proposed that further clinical studies are carried out with different concentrations and time periods. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-12-21 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://revistaseletronicas.pucrs.br/scientiamedica/article/view/11494 |
url |
https://revistaseletronicas.pucrs.br/scientiamedica/article/view/11494 |
dc.language.iso.fl_str_mv |
por eng |
language |
por eng |
dc.relation.none.fl_str_mv |
https://revistaseletronicas.pucrs.br/scientiamedica/article/view/11494/8617 https://revistaseletronicas.pucrs.br/scientiamedica/article/view/11494/8618 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Editora da PUCRS - ediPUCRS |
publisher.none.fl_str_mv |
Editora da PUCRS - ediPUCRS |
dc.source.none.fl_str_mv |
Scientia Medica; Vol. 22 No. 4 (2012); 191-196 Scientia Medica; v. 22 n. 4 (2012); 191-196 1980-6108 1806-5562 reponame:Scientia Medica (Porto Alegre. Online) instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) instacron:PUC_RS |
instname_str |
Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) |
instacron_str |
PUC_RS |
institution |
PUC_RS |
reponame_str |
Scientia Medica (Porto Alegre. Online) |
collection |
Scientia Medica (Porto Alegre. Online) |
repository.name.fl_str_mv |
Scientia Medica (Porto Alegre. Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) |
repository.mail.fl_str_mv |
scientiamedica@pucrs.br || editora.periodicos@pucrs.br |
_version_ |
1809101750016147456 |