Lipschütz Ulcer and Epstein-Barr Virus Infection: A Case Report

Detalhes bibliográficos
Autor(a) principal: Silva, Íris Santos
Data de Publicação: 2021
Outros Autores: Virtuoso, João, Ribeiro, Joana Filipe, Silva, Glória, Oliveira, Rita S.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Scientia Medica (Porto Alegre. Online)
Texto Completo: https://revistaseletronicas.pucrs.br/scientiamedica/article/view/39653
Resumo: Aims: Lipschütz ulcer (LU), also known as acute vulvar ulcer, is a rare cause of vulvar ulcerations of nonvenereal origin. Our aim is to alert about this manifestation of the disease and to prevent unnecessary treatment.Case description: we present a 15 years old female, without relevant family and past history, admitted in the emergency room with a painful vulvar ulcer, preceded by five days of fever and sore throat. On physical examination, she had enlarged, and erythematous tonsils and bilateral anterior cervical lymphadenopathy and the genital examination revealed vulvar oedema and a deep ulcer with necrotic plaques in labium minus. The exclusion of transmitted sexual disease led to a diagnosis of Lipschütz ulcer. She started symptomatic treatment, oral antibiotic and corticoid therapy. She was discharged from the hospital after 6 days of admission and returned to a consult one month later when it was observed an almost complete resolution of the lesions. No recurrences occurred until 3 months.Conclusion: LU is a misdiagnosed pathology, probably because doctors, in general, are not familiarized with that, and since the diagnosis is made by exclusion. Infectious, such as Epstein-Barr Virus infections, are proposed etiologies.
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spelling Lipschütz Ulcer and Epstein-Barr Virus Infection: A Case ReportÚlcera de Lipschütz e infecção pelo vírus Epstein-Barr: Um relato de casoadolescencelipschütz ulcerepstein-barr virusadolescênciaúlcera de lipschützvírus epstein-barrAims: Lipschütz ulcer (LU), also known as acute vulvar ulcer, is a rare cause of vulvar ulcerations of nonvenereal origin. Our aim is to alert about this manifestation of the disease and to prevent unnecessary treatment.Case description: we present a 15 years old female, without relevant family and past history, admitted in the emergency room with a painful vulvar ulcer, preceded by five days of fever and sore throat. On physical examination, she had enlarged, and erythematous tonsils and bilateral anterior cervical lymphadenopathy and the genital examination revealed vulvar oedema and a deep ulcer with necrotic plaques in labium minus. The exclusion of transmitted sexual disease led to a diagnosis of Lipschütz ulcer. She started symptomatic treatment, oral antibiotic and corticoid therapy. She was discharged from the hospital after 6 days of admission and returned to a consult one month later when it was observed an almost complete resolution of the lesions. No recurrences occurred until 3 months.Conclusion: LU is a misdiagnosed pathology, probably because doctors, in general, are not familiarized with that, and since the diagnosis is made by exclusion. Infectious, such as Epstein-Barr Virus infections, are proposed etiologies.Objetivo: a úlcera de Lipschütz, ou úlcera vulvar aguda, é uma causa rara de ulceração de origem não venérea. O nosso objetivo é alertar para essa manifestação da doença e prevenir tratamentos desnecessários.Descrição: adolescente, sexo feminino, 15 anos, sem história pessoal ou antecedentes familiares de relevo. Recorreu ao Serviço de Urgência por febre e odinofagia, com cinco dias de evolução, associada a uma úlcera vulvar dolorosa, que surgiu no próprio dia. O exame clínico revelou amígdalas hipertrofiadas e eritematosas, linfadenopatia cervical anterior, e o exame ginecológico apresentou edema da vulva e uma úlcera profunda, com placas necróticas nos lábios menores. A exclusão de uma doença sexualmente transmissível levou ao diagnóstico de úlcera de Lipschütz. Ficou internada no Serviço de Pediatria e iniciou tratamento sintomático, antibioterapia por sobreinfeção da úlcera e corticoterapia tópica. Teve alta após seis dias de hospitalização e foi reavaliada em consulta um mês depois, com resolução completa do caso. Não apresentou recorrência da úlcera até aos três meses seguintes.Conclusão: a úlcera de Lipschütz é uma doença subdiagnosticada, muito provavelmente porque os médicos não estão familiarizados com ela e por ser um diagnóstico de exclusão. A infeção pelo vírus Epstein-Barr é uma das etiologias propostas.Editora da PUCRS - ediPUCRS2021-12-20info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionRelato de caso raro ou de especial interesseapplication/pdfhttps://revistaseletronicas.pucrs.br/scientiamedica/article/view/3965310.15448/1980-6108.2021.1.39653Scientia Medica; Vol. 31 No. 1 (2021): Single Volume; e39653Scientia Medica; v. 31 n. 1 (2021): Volume Único; e396531980-61081806-556210.15448/1980-6108.2021.1reponame:Scientia Medica (Porto Alegre. Online)instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)instacron:PUC_RSenghttps://revistaseletronicas.pucrs.br/scientiamedica/article/view/39653/27275Copyright (c) 2021 Scientia Medicahttp://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSilva, Íris SantosVirtuoso, JoãoRibeiro, Joana FilipeSilva, GlóriaOliveira, Rita S.2022-01-31T16:31:10Zoai:ojs.revistaseletronicas.pucrs.br:article/39653Revistahttps://revistaseletronicas.pucrs.br/scientiamedica/PUBhttps://revistaseletronicas.pucrs.br/scientiamedica/oaiscientiamedica@pucrs.br || editora.periodicos@pucrs.br1980-61081806-5562opendoar:2022-01-31T16:31:10Scientia Medica (Porto Alegre. Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)false
dc.title.none.fl_str_mv Lipschütz Ulcer and Epstein-Barr Virus Infection: A Case Report
Úlcera de Lipschütz e infecção pelo vírus Epstein-Barr: Um relato de caso
title Lipschütz Ulcer and Epstein-Barr Virus Infection: A Case Report
spellingShingle Lipschütz Ulcer and Epstein-Barr Virus Infection: A Case Report
Silva, Íris Santos
adolescence
lipschütz ulcer
epstein-barr virus
adolescência
úlcera de lipschütz
vírus epstein-barr
title_short Lipschütz Ulcer and Epstein-Barr Virus Infection: A Case Report
title_full Lipschütz Ulcer and Epstein-Barr Virus Infection: A Case Report
title_fullStr Lipschütz Ulcer and Epstein-Barr Virus Infection: A Case Report
title_full_unstemmed Lipschütz Ulcer and Epstein-Barr Virus Infection: A Case Report
title_sort Lipschütz Ulcer and Epstein-Barr Virus Infection: A Case Report
author Silva, Íris Santos
author_facet Silva, Íris Santos
Virtuoso, João
Ribeiro, Joana Filipe
Silva, Glória
Oliveira, Rita S.
author_role author
author2 Virtuoso, João
Ribeiro, Joana Filipe
Silva, Glória
Oliveira, Rita S.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Silva, Íris Santos
Virtuoso, João
Ribeiro, Joana Filipe
Silva, Glória
Oliveira, Rita S.
dc.subject.por.fl_str_mv adolescence
lipschütz ulcer
epstein-barr virus
adolescência
úlcera de lipschütz
vírus epstein-barr
topic adolescence
lipschütz ulcer
epstein-barr virus
adolescência
úlcera de lipschütz
vírus epstein-barr
description Aims: Lipschütz ulcer (LU), also known as acute vulvar ulcer, is a rare cause of vulvar ulcerations of nonvenereal origin. Our aim is to alert about this manifestation of the disease and to prevent unnecessary treatment.Case description: we present a 15 years old female, without relevant family and past history, admitted in the emergency room with a painful vulvar ulcer, preceded by five days of fever and sore throat. On physical examination, she had enlarged, and erythematous tonsils and bilateral anterior cervical lymphadenopathy and the genital examination revealed vulvar oedema and a deep ulcer with necrotic plaques in labium minus. The exclusion of transmitted sexual disease led to a diagnosis of Lipschütz ulcer. She started symptomatic treatment, oral antibiotic and corticoid therapy. She was discharged from the hospital after 6 days of admission and returned to a consult one month later when it was observed an almost complete resolution of the lesions. No recurrences occurred until 3 months.Conclusion: LU is a misdiagnosed pathology, probably because doctors, in general, are not familiarized with that, and since the diagnosis is made by exclusion. Infectious, such as Epstein-Barr Virus infections, are proposed etiologies.
publishDate 2021
dc.date.none.fl_str_mv 2021-12-20
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Relato de caso raro ou de especial interesse
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://revistaseletronicas.pucrs.br/scientiamedica/article/view/39653
10.15448/1980-6108.2021.1.39653
url https://revistaseletronicas.pucrs.br/scientiamedica/article/view/39653
identifier_str_mv 10.15448/1980-6108.2021.1.39653
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://revistaseletronicas.pucrs.br/scientiamedica/article/view/39653/27275
dc.rights.driver.fl_str_mv Copyright (c) 2021 Scientia Medica
http://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2021 Scientia Medica
http://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Editora da PUCRS - ediPUCRS
publisher.none.fl_str_mv Editora da PUCRS - ediPUCRS
dc.source.none.fl_str_mv Scientia Medica; Vol. 31 No. 1 (2021): Single Volume; e39653
Scientia Medica; v. 31 n. 1 (2021): Volume Único; e39653
1980-6108
1806-5562
10.15448/1980-6108.2021.1
reponame:Scientia Medica (Porto Alegre. Online)
instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron:PUC_RS
instname_str Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron_str PUC_RS
institution PUC_RS
reponame_str Scientia Medica (Porto Alegre. Online)
collection Scientia Medica (Porto Alegre. Online)
repository.name.fl_str_mv Scientia Medica (Porto Alegre. Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
repository.mail.fl_str_mv scientiamedica@pucrs.br || editora.periodicos@pucrs.br
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