Sífilis congênita em Sorocaba: incidência e aspectos clínicos em mães e recém-nascidos

• Autor(a) principal: Turigoe, Gabriela Vieira
• Data de Publicação: 2023
• Outros Autores: Belmont, Thaís de Oliveira
• Tipo de documento: Trabalho de conclusão de curso
• Idioma: por
• Título da fonte: Biblioteca Digital de Teses e Dissertações da PUC_SP
• Texto Completo: https://repositorio.pucsp.br/jspui/handle/handle/40325
• topic: CNPQ::CIENCIAS DA SAUDE::ENFERMAGEM; Sífilis; Transmissão vertical; Sífilis congênita; Incidência; Perfil epidemiológico; Syphilis; Vertical transmission; Syphilis congenital; Incidence; Epidemiological profile

Objective: to verify the incidence of congenital syphilis and describe the epidemiological profile of mothers and newborns diagnosed in the municipality of Sorocaba in the period from 2018 to 2022, through sociodemographic variables and clinical aspects of the compulsory notification form. Methods: quantitative, observational, descriptive and inferential study, carried out with a compulsory notification database, of confirmed cases of congenital syphilis in the period of the last 5 years (2018-2022), in the municipality of Sorocaba, identified by the collection in the secondary database of SINAN obtained from the Municipal Center for Specialized Care – CMAE. Results: the incidence of congenital syphilis in the period was 3.66 new cases per 1,000 live births in Sorocaba. The maternal profile showed that most of the mothers were young people aged 14 to 30 years, self-declared white, with unknown schooling, who were diagnosed with syphilis during prenatal care and who had undergone inadequate treatment with an untreated partner. The profile of the newborn showed age at diagnosis between 1 and 7 days of life, white ethnicity, VDRL test collected from peripheral blood with a reactive result, VDRL test in non-reactive cerebrospinal fluid, X-ray of long bones with no alterations, asymptomatic clinical diagnosis, with the presence of jaundice in 13% of the cases, who underwent the treatment regimen with crystalline Penicillin G (100.00 to 150,000 IU/kg/day – 10 days) and survival for the evolution of the case. Statistically significant associations were observed between adequate maternal treatment in the following variables: mother's schooling, in the "higher education" category; treated partner(s) who have undergone treatment; gender of the newborn, within the "ignored" category and VDRL test in cerebrospinal fluid in the "reagent" category. Conclusion: it is concluded that the vertical transmission of syphilis in the city of Sorocaba continues, due to the lack of adherence of pregnant women and partners to the treatment regimen that should be started early.